Blood Disorders
PATH 26505 3(2-1)
Prof. Dr Raheela Akhtar
Blood disorders
• Anemia
• Leukemia
• Lymphomas
• Lymphoproliferative disorders,
• Thombocytopenia
• Thrombasthenia
• Enzymopathies
• Membranopathies
• Hemoglobinopathies
• Plasma cell dyscariasis
Bleeding disorders
• Vitamin K deficiency bleeding.
• Von Willebrand disease
• Hemophilia (A, B, C)
• Vitamin K deficiency
• Hereditary Hemorrhagic telangiectasia (HHT)
• Other rare types of inherited bleeding
disorders, such as factor I, II, V, V + VIII, VII, X, XI,
or XIII deficiencies,
• Fibrinolytic disorders
Bleeding disorders
• Kahler disease
• Multiple Myeloma
• Myeloproliferative disorders
• Myelodysplastic syndrome
Coagulation disorders
• DIC
• Paroxysmal nocturnal hemoglobinuria (PNH)
• ITC (idiopathic thrombocytopenic purpura)
• HUS (hemolytic uremic syndrome)
• Antiphospholipid syndrome
• Factor V Leiden
• Deep vein thrombosis
• Bernard soulier syndrome
• Glanzman Thrombasthenia
• Wiskott Aldrich Syndrome
• May-Hegglin anomaly
• Gray platelet syndrome
• Neonatal alloimmune thrombocytopenia
Learning Objectives of Blood
Disorder subject for MLT Student
Prescribed Skills
• Phlebotomy
• Blood preservation (hematology)
• Hematological procedures for common blood disorders
• Smear Making
• Staining procedures for blood and BM
• Slide identification
• Laboratory testing for Hemophilia, Thalassemia, Leukemia and anemia
• Hb Electrophoresis
• Flowcytometry
• General bleeding disorder tests (bleeding time, clotting time, Coomb’s
test)
• Specific bleeding disorder tests (Platelet count, PT, APTT)
Questions
• Which bleeding disorder causes bone pain?
• In which bleeding order nervous symptoms
appear?
• In which bleeding disorder blood becomes
chocolate colour?
• Which blood disorder can be associated by food
(eating beans)?
• Most common bleeding disorder in the world?
• Most common bleeding disorder in Pakistan?
• Mostly affect boys because defective gene on
the X-chromosome.