IGCSE Biology: Human Nutrition Overview
IGCSE Biology: Human Nutrition Overview
SECTION 2 LESSON 3
Content
Section 2
a) Levels of organisation
b) Cell structure
Structures c) Biological molecules
and d) Movement of substances
functions into and out of cells
in living e) Nutrition
organisms f) Respiration
g) Gas exchange
h) Transport
i) Excretion
j) Coordination and
response
Content
Flowering plants
2.15 describe the process of photosynthesis
Lesson 2 and understand its importance in the
conversion of light energy to chemical energy
2.16 write the word equation and the balanced
chemical symbol equation for photosynthesis
e) Nutrition 2.17 understand how varying carbon dioxide
concentration, light intensity and temperature
affect the rate of photosynthesis
2.18 describe the structure of a leaf and
explain how it is adapted for photosynthesis
2.19 understand that plants require mineral
ions for growth and that magnesium ions are
needed for chlorophyll and nitrate ions are
needed for amino acids
2.20 describe experiments to investigate
photosynthesis, showing the evolution of
oxygen from a water plant, the production of
starch and the requirements of light, carbon
dioxide and chlorophyll
Content
Humans
2.21 identify sources and describe functions of
Lesson 3 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
Types of nutrition
AUTOTROPHS –organisms that can
produce complex organic
compounds from simple inorganic
molecules.
They are the PRODUCERS in a food
chain.
Our diet
needs to
contain
sufficient and
balanced
quantities of
carbohydrate
s, proteins
and lipids.
Biological molecules
carbohydrates
Different foods contain Sugar gives us
different kinds of sugar.
Eg fruit contains energy, so we
Sugar fructose or glucose. call it an energy
Lactose is in milk. Table
sugar is sucrose. food.
Starch
Cellulose
Biological molecules
carbohydrates
Different foods contain Sugar gives us
different kinds of sugar.
Eg fruit contains energy, so we
Sugar fructose or glucose. call it an energy
Lactose is in milk. Table
sugar is sucrose. food.
Starch is found Starch is a storage
particularly in molecule, but it
Starch bread, potatoes does provide us
with energy.
and cereals.
Cellulose
Biological molecules
carbohydrates
Different foods contain Sugar gives us
different kinds of sugar.
Eg fruit contains energy, so we
Sugar fructose or glucose. call it an energy
Lactose is in milk. Table
sugar is sucrose. food.
Starch is found Starch is a storage
particularly in molecule, but it
Starch bread, potatoes does provide us
with energy.
and cereals.
Cellulose is It is a structural
found in plant molecule, and
Cellulose cell walls supports the
plant cell.
Biological molecules
Fats
Rickets is a softening of
bones in children due to
deficiency or impaired
metabolism of vitamin D,
magnesium, phosphorus or
calcium, potentially leading
to fractures and deformity.
Rickets is among the most
frequent childhood diseases
in many developing
countries.
Components of our diet
Minerals: contain certain elements essential
for the proper functioning of our bodies.
Anaemia is a decrease
in the number of red
blood cells in the blood,
meaning that less
oxygen can be carried
by the blood to various
organs and tissues,.
The main symptoms are
tiredness and lethargy.
Components of our diet
Vitamins: a collection of organic substances
needed in small quantities in the body. Their
overall function is to help control the
chemical reactions taking place in the body.
Components of our diet
Vitamins: a collection of organic substances
needed in small quantities in the body. Their
overall function is to help control the
chemical reactions taking place in the body.
D provided
sunlight is
present.
Components of our diet
Fibre is necessary for a healthy balanced
diet, but the body can’t absorb it. It helps
our digestive system to process food and
absorb nutrients. It helps your bowel to pass
food by making stools soft and bulky. It
helps prevent constipation.
Fibre is found in foods such as brown rice,
oats, wholegrain breads and cereals.
Components of our diet
Water makes up more
than two-thirds of the
weight of the human
body. It serves as a
lubricant, helps
regulate body
temperature,
prevents and relieves
constipation. Without
enough water we can
become dehydrated.
The human digestive system
(also known as the alimentary canal)
salivary glands
oesophagu
s
liver
stomach
pancreas
large intestine
small intestine
anus
The human digestive system
In digestion,
large insoluble
molecules are
broken down into
smaller soluble
particles that can
be absorbed into
the bloodstream.
The human digestive system
Mouth – mechanical
chewing of the food.
Salivary glands
produce the enzyme
amylase which
begins breaking
down
polysaccharides into
simpler sugars.
The human digestive system
Oesophagus (also
known as the gullet).
Passes food down
from the mouth to
the stomach by a
process known as
peristalsis.
Peristalsis
Rings of muscle
around the
oesophagus
effectively
‘squeeze’ food
towards the
stomach, as you
would with
toothpaste in a
tube.
The human digestive system
Stomach – more
mechanical
digestion happens
here. The stomach
produces the
enzyme protease,
and also
hydrochloric acid
which kills bacteria,
and this acid also
provides the ideal
conditions for
protease.
The human digestive system
Pancreas – produces
many enzymes,
including amylase,
protease and lipase.
The human digestive system
Large intestine – as
the fibre and other
undigested material
passes along the
large intestine,
water is absorbed
from it, so it
becomes more solid.
This solid matter
then passes on to
the rectum where it
is stored as faeces.
The human digestive system
Digestion
Absorption
Assimilation
Egestion
Definitions
This is the process of taking in food
Ingestion substances through the mouth.
Digestion
Absorption
Assimilation
Egestion
Definitions
This is the process of taking in food
Ingestion substances through the mouth.
Absorption
Assimilation
Egestion
Definitions
This is the process of taking in food
Ingestion substances through the mouth.
Assimilation
Egestion
Definitions
This is the process of taking in food
Ingestion substances through the mouth.
Egestion
Definitions
This is the process of taking in food
Ingestion substances through the mouth.
This is the mechanical and chemical
Digestion breakdown of food into smaller, more
soluble, components.
This is the process of taking soluble
food through the wall of the small
Absorption intestine by diffusion into the blood
stream.
This is the process whereby absorbed
food is altered chemically by the liver
Assimilation or chemical substances before being
utilised by the cells of the body.
This is the process where solid
Egestion undigested food material is removed
from the digestive system via the anus.
Mouth
• Teeth mechanically • Epiglottis is a flap-like
break down food into structure at the back of
small pieces. Tongue the throat that closes
mixes food with saliva over the trachea
(contains amylase, preventing food from
which helps break down entering it. It is located
starch). in the Pharynx.
B. Functions of the Digestive System
1. Ingestion:
2. Mastication:.
3. Propulsion
– Deglutition: swallowing
– Peristalsis:
– Mass movements
– chyme
24-53
I. Functions of Saliva
– 1. Prevents bacterial
infection
– 2. Lubrication
– 3. Contains salivary
amylase that breaks
down starch into
disaccharides
– 4. Helps to form
bolus for deglutition
– 5. Parasympathetic
input causes salivary
production
– 6. Sympathetic
stimulation leads to
thick mucoid saliva
24-54
I. Swallowing (Deglutition)-three phases
– 1. Voluntary: bolus of food moved by tongue from
oral cavity to pharynx.
– 2. Pharyngeal: reflex.
– a. Controlled by swallowing center in medulla
oblongata.
– b. Soft palate elevates, upper esophageal sphincter
relaxes,
– c. elevated pharynx opens the esophagus,
– d. food pushed into esophagus by pharyngeal
constrictors’ successive contraction from superior to
inferior.
– e. Epiglottis is tipped posteriorly due to pressure of
the bolus,
– f. larynx elevated to prevent food from passing into
larynx.
– 3. Esophageal: reflex. Stretching of esophagus causes
enteric NS to initiate peristalsis of muscles in the
esophagus. 24-55
3. Secretions of the Stomach
• Chyme: ingested food plus stomach secretions
• Mucus:
– Viscous and alkaline
– Protects from acidic chyme and enzyme pepsin
• HCl: parietal cells
– Kills bacteria
– Stops carbohydrate digestion by inactivating salivary amylase
– Denatures proteins
– Helps convert pepsinogen to pepsin
• Pepsinogen: packaged in zymogen granules released by exocytosis.
Pepsin catalyzes breaking of covalent bonds in proteins
24-56
H. Functions of the Liver
• 1. Bile production: 600-
1000 mL/day. Bile salts
(bilirubin), cholesterol,
fats, fat-soluble
hormones, lecithin
– Neutralizes and
dilutes stomach acid
– Bile salts emulsify
fats. Most are
reabsorbed in the
ileum.
– Secretin (from the
duodenum)
stimulates bile
secretions, increasing
water and
bicarbonate ion
content of the bile
• 2. Storage
– Glycogen, fat,
vitamins, copper and
iron. Hepatic portal
blood comes to liver 24-57
from small intestine.
• 3. Nutrient interconversion
– Amino acids to energy producing compounds
– Hydroxylation of vitamin D. Vitamin D then travels to
kidney where it is hydroxylated again into its active
form-promotes bone growth and absorption of calcium
• 4. Detoxification
– Hepatocytes remove ammonia and convert to urea
• 5. Phagocytosis
– Kupffer cells phagocytize worn-out and dying red and
white blood cells, some bacteria
• 6. Synthesis
– Albumins, fibrinogen, globulins, heparin, clotting
factors
24-58
X. Pancreas
• A. Pancreas both
endocrine and exocrine
• B. Endocrine: pancreatic
islets or Islets of
Langerhans.
• C. Exocrine: groups acini
(grape-like cluster) form
lobules separated by septa.
• D. Aqueous. Bicarbonate
lowers pH inhibiting pepsin
and providing proper pH
for enzymes
• E. Enzymatic portion:
– Trypsinogen
– Chymotrypsinogen
– Procarboxypeptidase
– Pancreatic amylase
– Pancreatic lipases
– Deoxyribonucleases
and ribonucleases
24-59
XI. Large Intestine
• A. Extends from
ileocecal junction to
anus
• B. Consists of cecum,
colon, rectum, anal
canal
• C. Movements sluggish
(18-24 hours); chyme
converted to feces.
• D. Absorption of water
and salts, secretion of
mucus, extensive action
of microorganisms.
• E. 1500 mL chyme
enter the cecum, 90%
of volume reabsorbed
yielding 80-150 mL of
feces
24-60
XII. Digestion and absorption
A. Carbohydrates
1. Monosaccharide vs.
disaccharide vs.
polysaccharide
2. Carbohydrate
digestion begins in the
mouth-salivary
amylase
3. Nothing occurs in the
stomach as salivary
amylase is denatured
4. Pancreatic amylase
takes the carbo to the
disaccharide level
5. Epithelium of the small
intestine produces
disaccharidases
24-61
B. Protein digestion
• 1. amino acid vs. protein
• 2. initial breakdown
begins in stomach with
pepsin
• 3. continues in intestine
with trypsin,
chymotrypsin, and
carboxypeptidase
• 4. dipeptides are broken
down by peptidases from
epithelial cells of the
mucosa
24-62
C. Lipid digestion
• 1. categories of lipids
• a. phospholipids
• b. Triglycerides
• c. Cholesterol
• 2. diverse group but all
are hydrophobic
• 3. digestion
commences in the
small intestine with
pancreatic lipase and
bile salts
24-63
4. Transport of Lipids Across Intestinal Epithelium
24-64
5. Transport of Lipids in blood stream
• All lipids carried in the blood are done so in combination
with protein to make them soluble in plasma.
• Cholesterol: 15% ingested; 85% manufactured in liver and
intestinal mucosa
• Lipids are lower density than water; proteins are higher
density than water
• Chylomicrons: 99% lipid and 1% protein (extremely low
density); enter lymph
• VLDL: 92% lipid, 8% protein
– Form in which lipids leave the liver
– Triglycerides removed from VLDL and stored in
adipose cells. VLDL has been converted to LDL.
• LDL: 75% lipid, 25% protein
– Transports cholesterol to cells
– Cells have LDL receptors
– # of LDL receptors become less once cell’s
lipid/cholesterol needs are met.
• HDL: 55% lipid, 45% protein
– Transports excess cholesterol from cells to liver
24-65
Water and Ions
24-66
Biological molecules
Substrate Product
Enzyme
Sucrase
Enzyme summary
Salivary Gland -
produces amylase
which breaks down
carbohydrates (such
as starch) into simple
sugars (eg. glucose)
Enzyme summary
Stomach – produces
protease which
breaks down proteins
into amino acids
Enzyme summary
Pancreas – produces
amylase
(carbohydrates
sugars), protease
(proteins amino
acids), lipase (fats
fatty acids + glycerol)
Enzyme summary
Small intestine –
produces amylase
(carbohydrates
sugars), protease
(proteins amino acids),
lipase (fats fatty acids
+ glycerol)
Enzyme summary
One more thing
………….
Maltase, thought to
be produced by the
walls of the small
intestine, converts
the disaccharide
maltose (formed by
the action of amylase
on starch) into the
simple sugar glucose.
Content
Humans
2.21 identify sources and describe functions of
Lesson 1 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
Content
Humans
2.21 identify sources and describe functions of
Lesson 1 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
Content
Humans
2.21 identify sources and describe functions of
Lesson 1 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
Content
Humans
2.21 identify sources and describe functions of
Lesson 1 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
Content
Humans
2.21 identify sources and describe functions of
Lesson 1 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
Content
Humans
2.21 identify sources and describe functions of
Lesson 1 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
Content
Humans
2.21 identify sources and describe functions of
Lesson 1 carbohydrate, protein, lipid (fats and oils),
vitamins A, C and D, the mineral ions calcium and
iron, water and
dietary fibre as components of the diet
e) Nutrition 2.22 describe the structures of the human
alimentary canal and describe the functions of the
mouth, oesophagus, stomach, small intestine,
large intestine
and pancreas
2.23 understand the processes of ingestion,
digestion, absorption, assimilation and egestion
2.24 explain how and why food is moved through
the gut by peristalsis
2.25 understand the role of digestive enzymes, to
include the digestion of starch to glucose by
amylase and maltase, the digestion of proteins to
amino acids by proteases and the digestion of
lipids to fatty acids and glycerol by lipases
2.26 understand that bile is produced by the liver
and stored in the gall bladder, and understand the
role of bile in neutralising stomach acid and
emulsifying
lipids
End of Section 2 Lesson 3
Nutrition – human