SISTER NIVEDITA UNIVERSITY
TOPIC: PHARMACEUTICAL DOSAGE FORMS
NAMES: AEMAN ANIS , SNEHA
SAHA
SAKLIN ISLAM ,
NASIM AKTAR
DEBAPRIYO MITRA
STREAM: [Link]
YEAR: 1ST YEAR
SEMESTER: 2ND SEMESTER
MENTOR SEMINAR~ 5170011602
(J.C BOSE GROUP~ PROFESSOR SATHI
SARKAR)
CONTENTS
1. INTRODUCTION
2. SOLID DOSAGE FORMS
3. UNIT DOSAGE FORMS
4. AND ITS TYPES
5. BULK DOSAGE FORMS- POWDER
6. LIQUID DOSAGE FORMS-
7. ADVANTAGES/ DISADVANTAGES
8. SEMI-SOLID DOSAGE FORMS-
9. ADVANTAGES/ DISAGVANTAGES
10. GASEOUS DOSAGE FORM
11. CONCLUSION
12. REFERENCES
13. THANKYOU
INTRODUCTI
ON Drug molecules/APIs
are delivered to sites
DOSAGE FORM of action within the DOSAGE FORM
OF DRUGS
body to produce
optimum desired
( MEDICINES) =
effects and minimum
API+Excipients
adverse effects.
DRUG ( ACTIVE It is the part of
DOSAGE FORM
PHARMACEUTI any drug that
Drug molecules are
CAL produces its
delivered to sites of
INGREDIENTS ) effects .
action within the
body .
NEED OF DOSAGE FORMS :
• Provide safe and convenient delivery of
accurate dosage. E.g.- Tablets ,
capsules , syrups
• Protect drug substances from DRUG ( ACTIVE
atmospheric oxygen . E.g.- Coated
capsules , sealed capsules
PHARMACEUTICAL
INGREDIENTS )
SOLID DOSAGE
FORMS
The solid dosage forms are the most used
dosage form because of the stability and ease
of mass production. These dosage forms are
mainly available in unit dosage forms but are
also available in bulk dosage forms.
POWDERS
TYPES OF SOLID DOSAGE FORMS
Unit dosage form Bulk dosage forms
1. Tablet 1. Fine powder and CAPSULES
2. Capsules granules
3. Pills 2. Dusting powders
4. Sachets 3. Insufflators TABLETS
5. Lozenges 4. Dentifrices PILLS
UNIT DOSAGE FORMS
1. TABLETS
• These are unit dosage forms consisting of
active ingredient and suitable
Pharmaceutical Excipients.
• Tablets may vary in size, shape, weight,
hardness thickness and in other aspects.
TYPES OF TABLETS:
1. Tablets for oral administration
2. Tablets for vaginal administration
3. Tablets for implantation
2. CAPSULES
• These are the unit dosage forms consisting of
gelatin shell that breaks often after the capsule
has been swallowed. These are of two types,
Hard gelatin capsule- Two pieces fit together
and hold the drug, either powder or granular
form.
Soft gelatin capsule- One piece with drug, which
is usually in liquid form inside the shell.
• Drugs are easily absorbed from these mixtures
offering two distinct advantages:
1. Quicker effect,
2. Drug absorbed more effectively, so lower doses
can be used.
3. PILLS:
Small rounded solid dosage form consisting medicament
intended for oral use. These are small spherical or ovoid
masses which are required to be made at dispensing
counters.
4. CACHETS:
Solid dosage forms. Drugs enclosed with wafer sheet of
rice.
[Link]:
Solid preparations containing sugar and gum used to
medicate mouth and throat.
BULK DOSAGE FORMS
POWDERS
These are the solid form of medicament used for internal and
external use. They are available in crystalline and
amorphous form.
1. FINE POWDER AND GRANULES-These are Finely
divided solid drugs or mixture of drugs for internal or
external use.
2. DENTRIFICES- It includes tooth powder, toothpaste,
which are used along with a toothbrush to clean and
polish natural teeth.
LIQUID DOSAGE FORMS
The liquid form dosage of a
drug is for administration or
consumption.
Route of administration may be
oral, intravenous, intramuscular,
cutaneous, subcutaneous, etc.
Liquid dosage forms are divided into
two parts according to the phase.
1. Monophasic liquid dosage form
2. Biphasic liquid dosage form.
ADVANTAGES DISADVANTAGES
Liquid dosage forms are flexible It needs a lot of special storage
to take a proper those than solid
dose. conditions.
The rate of absorption of the Less stable than other doses.
liquid dosage form is so faster
than the solid dosage form.
SEMI-SOLID DOSAGE FORMS
Semi solid dosage forms are the tropical dosage form
used for the therapeutic, protective, or cosmetic
[Link] may be applied to the skin, nasal, vaginal,
or rectal cavity.
Ointments, pastes, cream, gels are the examples of
semi solid dosage forms.
ADVANATGES DISADVANTAGES
It is used externally. It may cause staining.
More stable than liquid dosage form. They are bulky to handle.
Suitable dosage form for bitter drugs. It may cause irritation or allergy to
some patients.
GASEOUS
DOSAGE FORM
GASEOUS DOSAGE FORMS
ARE PACKED IN A
CONTAINER WHICH GETS
RELEASED UPON APPLYING
PRESSURE. THE GAS
INSIDE CONTAINS
THERAPEUTICALLY ACTIVE
MEDICAMENTS.
ADVANTAGES DISADVANTAGES
ADMINISTER EASILY AND QUICKLY. ONLY FEW DRUGS ARE USED.
ENHANCED STABILITY. NOT SUITABLE FOR IRRITANT DRUGS.
ADOSE CAN REMOVE WITHOUT
CONTAMINATION OF MATERIALS.
CONCLUSION
UNDERSTANDING THE
EFFECT OF INGREDIENTS
ON PRODUCT STABILITY .
THE POSSIBILITY OF
SIMPLIFYING COMPLEX
PROCESSES LEADING TO
NEW FORMULATION
DEVELOPMENT
CONSIDERING ALL THE
REQUIRED PARAMETERS
PROPERLY FOR THE
EQUIPMENT'S USED WITH
THEIR PROPER HANDLING .
REFERENCES
1. MEHTA. R.M; DISPENSING PHARMACY; VALLABH PRAKASHAN;
DOSAGE FORMS; ISBN-10: 8185731721.
2. AGARWAL.G; PHARMACEUTICS-1 THEORY AND PRACTICAL; CBS
PUBLISHERS & DISTRIBUTORS; PHARMACEUTICAL DOSAGE
FORMS; ISBN- 9789387964204.
3. SHIVPUJE SHIVRAJ.S, SINGH MEERA.C, VISHWE PRADNYA.S;
PHARMACEUTICS-1; TECHNICAL PUBLISHERS; DOSAGE FORMS;
ISBN- 978-93-332-1891-7
4. DR. GAUD.R.S, DR. YADAV A.V, DR. YEOLE P.G, GOKHALE S.B;
TEXTBOOK OF PHARMACEUTICS; NIRALI PRAKASHAN,
EDUCATIONAL PUBLISHERS; 20TH EDITION; ISBN-
9788185790411.