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Overview of Lymphoid Tissue Functions

The document provides an overview of lymphoid tissue and its role in the immune system, highlighting the differentiation between self and foreign structures, immune responses, and long-term antigen memory. It details various lymphatic organs including lymph nodes, spleen, thymus, palatine tonsils, and Peyer's patches, describing their structure and functions in immune response and blood cell formation. Key immune cells such as lymphocytes and antigen-presenting cells are also mentioned.

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Akhil Ansary
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110 views10 pages

Overview of Lymphoid Tissue Functions

The document provides an overview of lymphoid tissue and its role in the immune system, highlighting the differentiation between self and foreign structures, immune responses, and long-term antigen memory. It details various lymphatic organs including lymph nodes, spleen, thymus, palatine tonsils, and Peyer's patches, describing their structure and functions in immune response and blood cell formation. Key immune cells such as lymphocytes and antigen-presenting cells are also mentioned.

Uploaded by

Akhil Ansary
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd

Summary of Lymphoid

tissue.
Introduction
The immune system –
- Differentiate between self (own) and
foreign structures – specificity
- Immune response - fights against
pathogens
- Remember antigens over long period of
time

Cells of the immune system:


– Lymphocytes :T, B
– Antigen presenting cells (APC):
Dendritic cells, macrophages.
LYMPHATIC ORGANS
LYMPH NODE

Bean-shaped
Hilum
Afferent &
Efferent
lymphatic
vessels
SPLEEN

• Largest lymphatic organ


• Location – Upper left quadrant of
abdomen
• Rich blood supply
• Filters blood
• Reacts to blood borne antigen
Contains Lymphocytes, special
vascular spaces, meshwork of
reticular cells and fibres and
macrophages
Functions of Spleen
Immunological Haemopoietic
• Proliferation of • Formation of
lymphocytes blood cells in
• Production of foetal life.
Antibodies • Destruction of
RBC.
• Removal of antigen
from blood • Storage of Blood.
Red pulp
White pulp
THYMUS - FEATURES  Cells of Thymus are–
 Capsule- which sends septa that divide the lobes 1. Epithelial cells,
into Thymic lobules. 2. Lymphocytes &
 Cortex – High concentration of 3. Macrophages.
lymphocytes, Basophilic, Small
lymphocytes
 Medulla- Lymphocytes are less in number and
larger, stains lightly
 Hassall’s corpuscles in medulla.
 Trabeculae does not form true lobule
s
 Cortical caps over portions of
continuous medullary tissue
PALATINE TONSIL
• Lymphoid tissue associted with oropharyngeal mucosa
• Supported internally by reticulin fibres
• Lymphoid follicles
• Mucosa are invaginated into crypts which are covered by
Stratified squamous non-keratinised epithelium(oral cavity)
PEYERS PATCHES
 Peyer's patches (or aggregated lymphoid
nodules) are organized lymphoid nodules.
 Microscopically, Peyer’s patches appear as
oval or round lymphoid follicles (similar to
lymph nodes) located in the lamina propria
layer of the mucosa and extending into the
submucosa of the ileum.
 In adults, B lymphocytes are seen to
predominate in the follicles' germinal centers. T
lymphocytes are found in the zones between
follicles.

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