Cronic Renal Failure
Nuraeny, SKM, [Link]
Progressive reduction of functional renal tissue such as
that remaining kidney mass can no longger maintain the
body’s internal environment
Patology and risk factor
Cronic glomerulonephritis, ARF, polycystic kidney
disease, and nephrotoxins are some of the etiology of
CRF
Sign & symptom
Blood pressure is increased
Urea accumulates,
Potassium
Erythropoietin synthesis is decreased causing anemia.
Fluid volume overload symptoms may range from mild edema to life-
threatening pulmonary edema.
Metabolic acidosis (due to accumulation of sulfates, phosphates, uric acid etc.)
Iron deficiency anemia, which increases in prevalence as kidney function
decreases, is especially prevalent in those requiring haemodialysis