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The document provides a detailed table of various caffeoylquinic and dicaffeoylquinic acids, including their abbreviations, formulas, and quantitative measurements in two different aqueous extracts (BEN-CAW-8 and CAW-R61-12). It highlights the significantly higher amounts of these compounds in the BEN-CAW-8 extract compared to CAW-R61-12. Additionally, it mentions the use of a formulated rodent diet containing CAW in a preclinical study to investigate cognitive effects.

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wongbumi
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7 views3 pages

What If

The document provides a detailed table of various caffeoylquinic and dicaffeoylquinic acids, including their abbreviations, formulas, and quantitative measurements in two different aqueous extracts (BEN-CAW-8 and CAW-R61-12). It highlights the significantly higher amounts of these compounds in the BEN-CAW-8 extract compared to CAW-R61-12. Additionally, it mentions the use of a formulated rodent diet containing CAW in a preclinical study to investigate cognitive effects.

Uploaded by

wongbumi
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

12:40 440

Compound Abbreviation Formula Q1 Q3


(m/z) (mny

5-0 5-CQA CGH1sO9 353 191

caffeoylquinic

acids

4-0 4-CQA CsHgO9 353 173

caffeoylquinic

acids

3-0 3-CQA CioH1sOg 353 191

caffeoylquinic

acids

1,3 1,3-DicQA CzsH24012 515 17S

Dicaffeoylquinic

acids

3,4 3,4-DicQA CzsH24012 515 173

Dicaffeoylquinic

acids

3,5 3,5-DiCQA C25H24012 515 191

Dicaffeoylquinic

acids

1,5 1,5-DicQA CzsH24012 515 191

Dicaffeoylquinic

acids

4,5 4,5-DiCQA CzsHz4012 515 173

Dicaffeoylquinic

acids

madecassoside MS CastH7g020 1019* 973

asiaticoside AS CasHzsO19 1003* 957


12:40 40 9 3.98
KB/S ll l (11

caffeoylquinic

acids

4-0 4-CQA CisHis09 353 173

caffeoylquinic

acids

3-0 3-CQA CisH1g09 353 191

caffeoylquinic

acids

1,3 1,3-DicQA CzsH24012 515 179

Dicaffeoylquinic

acids

3,4 3,4-DiCQA CzsH24012 515 173

Dicaffeoylquinic

acids

3,5 3,5-DicQA CzsH24012 515 191

Dicaffeoylquinic

acids

1,5 1,5-DicQA CzsH24012 515 191

Dicaffeoylquinic

acids

4,5 4,5-DiCQA CzsH24012 515 173

Dicaffeoylquinic

acids

madecassoside MS CastHzg020 1019* 973

asiaticoside AS CagtHzg019 1003* 957

madecassic acid MA CgoH48O6 549* 503

asiatic acid AA CzoH48O5 533* 48;

Digoxin-d3 NA C4jH61D,014 828* 782


12:37 A4O *. 1.36
KB/s ll 12

thetwo preparations; each CQA in BEN-CAW-8 1S

approximately 2-4 times the amount of the


corresponding CQA in CAW-R61-|2 (Table3).Of
note, BEN–CAW-8 and CAW-R61-12 were

prepared from different CA plant materials.

Table [Link] content of 12 bioactive


compounds in two different CA aqueousextracts,
BEN--CAW-8 and CAW-R61-J2.

Compound Amount in BEN Amount in CAW


CAW-8 (mglg) R61-J2 (mng/g)

5-CQA 3.40+0.19 1.81 +0.05

4-CQA 3.03 ±0.21 1.28+0.07

3-CQA 7.21 +0.42 2.74+0.08

1,3-DicQA 2.49+0.14 0.55+0.03

3,4-DicQA 2.33t0.16 0.83+0.02

3,5-DicQA 2.01+0.23 0.87+0.03

1,5-DicQA 3.86+0.30 0.94+0.02

4,5-DicQA 2.15+0.14 0.97+0.03

MS 34.46+1.32 30.23+0.84

AS 14.58+1.00 20.40+0.50

MA 1.40+0.20 2.03+0.21

AA 0.79+0.15 1.87+0.33

A formulated rodent diet containing CAW (1%


w/w) used by our group in a preclinical study to

explore the role of TT and CQA in the cognitive


effects of CAW demonstrated that COA reverces

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