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Practical

The document discusses various aspects of pathology, including clinical features, types of lesions, and neoplasia. It covers benign and malignant tumors, their characteristics, and histological observations. Additionally, it touches on diseases such as malaria and trichomoniasis, along with diagnostic techniques and specimen analysis.

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0% found this document useful (0 votes)
40 views43 pages

Practical

The document discusses various aspects of pathology, including clinical features, types of lesions, and neoplasia. It covers benign and malignant tumors, their characteristics, and histological observations. Additionally, it touches on diseases such as malaria and trichomoniasis, along with diagnostic techniques and specimen analysis.

Uploaded by

thugsena39
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Intro

to Pathology
,
issue
processing

Pathologyelial re clicical
features (signs & symptoms)

Pillars of niflaration
Pathology :
lar
adaptation .
① ventriculas

reypectrophy
grouspecimen macoscopy- seem ein-valuulal
abnormalities
-

wortation
>
- Her wi vessels of yotime
A aorta.
Y ·
post menopausal . women

Dystrophicalitie
Dalto atropy it
the
(No Slide)

Gross .

"we vi
formalin
mounted specimen of that
pathog
sprince- a
Neural Formalin
Buffered ↓
"On observation we can see

that
recreased thickers of If Ventricle so

that it isventricular
quiel me a due

hypertrophy aspecimen"
Benign lesion
.

of origin)
>
-

>
- Smooth Muscles (cell
/
in
See mostly
Leiomyoma
.

Omg
Myometrics

sees in out section.


world
pattern

&
iseutely
Beign lesiouo smodeele a

mu
cigar shaped alls.
uposy Syphi Atomyosis Phinosporidosis
,
, ,

surrounded and
Th-crythroid
un
all mals
lymphoid cells plasmen
cesses
along
oh
langham's giant .
all

Ha
-

INTESTINES
-
(vicreased thickness).
wall
fibrosis
rically
-
s
,
↓ >
- sticture formation
examination >
- serosa-white tubrels

LUNGS

Ribcalscolesionosition
it
onas

Leprosy - granuloma
catscode
omg
Surushing The

verue

epitentoid
Nessel -
almos

alon
e
Y

ver
40X

>
-
sheet of
histiocytes
·

polygonal
clear cells
of
.
peripheral
nucleus

·
Bacilli are seen in this neive

Barilli
2n
staining reponator
-

Sephilos
Edema &
Hyperemia

A comitation of fluid in
interstitial tissue
space
and
generalised : Cardial , unal

- bealised
carity
serous .
Distribution >
- :
inflammatory
,

dema
Typesof
- >
-
pressure
-
special
effectPitting
lymphatic
pulmonarya
- pitting
Non

types of fluid

. a
ansuatemanon
inflammat

edeme
Cardiac

Renal disease

anmohan
-refer
Neoplasia-Benign
specient slide-lipoma-Benign no plasm of
adipocytes
(Black coloured)
ence
of fibrous capsule &
circumscribed "
·

-
well
encapsulated y well
Abnormal :Kapsulated region o

capsular/ outel surface glistening


I pink wavy segment Septae
· -

smooth ·
+ Fibrons

yellowBerettwhichare mature
adije
cut
surface -

Appears a

tunoue
iconyowa-brigh of smoothpe l

gross- Mistopatologically
-
:

well
capsulated y nuclei
·

cigar shaped
non ·

circumscriped outer
appearance · whoiled
pattern
is
surface homogenous a shows
· cut

whored
appearance.
vessels
magiuas -
Two
types-Benign tumour
of the Blood

- carernous-

Capitary
·
most common on the
skii
surface

llavy--eaty
endotheliale e


Fibroadenoma
-
of Breast-Benign breast tumon

·
proliferation of fibrous stroma and the drets and
glands of the breast
·

mobile-fluctuates of mens. Cycle


#
monse in breast

capsulated Histologically-
Non
groes
-

will circusised
intracaualicular Pericanabicula
dete patentdete
compressed
squamous papitone Septa
prolification of squarious all in
figer like projectio
onal
-
carity -squamou
,
at Finger
Like

Neve- Melano
cyte treon

neste of melaro
>
-
underi
cytes
se
progression
-
:
>
-
geously they
rese is size upon

going deeper.
Osces
Marian a Cystadenoma
·
filled ferous fluid-yellow ,
straw coured, watery
.
grossly - multiloculated (Hurres Histology eumar alls

& by tall
kied
· muiloculated agt
·

cyst
Y
NEVER mention Sorons/Muons avoid cell
-

ent
arface-smooth a glistening
homogenous single carity
Deid
Cyst -
:

mined turous of all


gor layers

cy "nei contanie aleal


.
cells
slides

① Lipoma
104 40X
4x-
compressed adipocytes
+
ecentrically
Nucleus

>


Licomyoma
.

4X 10 X 40X

proced appearance momma i toplasm

·
garden i

newangiomas
-
:

a)
Cappitaryangiomas
-
:

4X 10X 90X .

spiders
~ Capillary of
this endo the eve
.

·
~

! lobules
!
separated by
of capillaries
thin
clusters . septa containing
clustered this walled
of
capitaries
be hemangios
as

now
we

10X 40X

sugeaa
spaces

mig
y

use
large

!
single layer of endotheliure
roadenoma :

b)
ux- a) Intravaualicular
pericanalicular.

u
nicular

~
10 X
peri

X
p
Intro
⑤ Squamous papiloma
stratifiedsquare
stratifi
?
9X
10 X

⑤ Lerous
Cyst
adenoma :- -

Pinromuscul
sure

vid
Cystofal :

pitise
4X

Have
squamous

sch

44
se
News

4x 10 X

O
O
40X -

(.
Guests
of memoryes
differentiatingcy -Lionyona)
Best

Neoplase-Malignant
- :

netastas's bioneosarcoma
M-aupee
-

polarity
1-inatio

lear
-grown pero norphism

N
① squamous cell Carceioma

Mostcommon Skii derwin


Microscope-under the presence of
Cancer

geoes-hypespuatori poorly differentiatedRelate


pea
formed exceue
by all proliferation
① Basal all caroma ofsquacious
with mild
Rodent ulor-flower
pit appearance
a ,

promorphesne
Adeno carcinoma color ·
can have melanin
pigment
·

waso-rifitrative growth (geonly


cells (diff squacious cells Malignant melanoma
ollongated
-

Aassymetry Bre
c-variations in erou?
Diameter 76mm
E
-
guess specimens -

Malignant
.
gross specimens-Benign-
Microscopy Malignant
-
-

① squamous all carcinoma.

9X 10 X

nati
O .

ntelea
>
-
Bridges

Or

cosinophilic cytoplasm .

40X

encesrated
siny

squamous
all,I
forming the
Keratin .
pearl
② Adenocarcinoma

SX

10 X

-
2 mine propria
submucose

presence of Mun.

elongated
glands .

Malignant
Melanoma

-
igment
-Melanie
④ Basal Cell Carcinoma

-while

!
Basiloid cells
.

&et a t a r s
Malaria-Plasmodium
Female
Definitive host
mosquito
anopheles /Malaria
:

Intermediate host : Human eyele [sural a Asennal].

starred with
>
-

stains
Romanowsky's
methods blood (thick 2 Her
Diagnostic peripheral
swear
-

Fielde stain
·

Flouro out Smeal (Sure cases


stain
·
Kawanuto
technique
·

giensa
Stavi : arcideie
·
hishman's start
orange
·

stair
floroscult microscope wright's
·

Nuclear DNA-

Blood smear
>
-

peripheral

Tophate
Ring.

Trophozite larger that the


Ring form
-

o gametagh
forman
a end

-
merogies
·

p
then
Routin detection
Antigen
test
Practice post
-
-

Dot elisa
technique (IISER workshop)
Souve/Saginata-Cysticosis
Tarma

-suckers .

-sues
Trichomonas
Vaginalis

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