ASCRS PREOPERATIVE
OSD ALGORITHM
PREOPERATIVE VISIT
NONINVASIVE REFRACTIVE PREOP MEASUREMENTS
≥ 2 week CL holiday/
(e.g., keratometry, topography, optical biometry, aberrometry, etc.)
no drops within 2 hours prior
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OSD SCREEN
symptoms? signs?
ASCRS SPEED II Preop Questionnaire Osmolarity Inflammatory Marker (MMP-9) Lactoferrin
NEGATIVE SCREEN (All normal) POSITIVE SCREEN (Any abnormality)
OSD UNLIKELY OSD LIKELY
To help establish OSD subtype and visual significance
OPTIONAL NONINVASIVE OSD TESTS
(e.g., meibography, topography, NI-TBUT, OCT TMH, OSI, aberrometry, LLT)
CLINICAL EXAM (LLPP)
Stain (dye instillation):
Look: Lift: Pull: Push: Corneal Nerve
Corneal staining?
Blink, lids, lashes, Upper lid, examine Assess lid laxity Meibomian gland Sensitivity Testing
TBUT? +/–Schirmer’s)
interpalpebral surface superior surface ‘floppy eyelids,’ fornices expression
OSD RULED IN
OSD RULED OUT
Any combination of abnormal signs and/or symptoms;
No symptoms/No signs/Normal exam/No corneal staining
visual significance based on results of above
+/- Symptoms
NEUROPATHIC PAIN VS. EARLY SITUATIONAL OSD/DED NEUROTROPHIC
Symptoms/No signs/Normal Exam/ Stain No Symptoms/ Signs/ Exam/ Stain
< Signs > Signs
NON-VISUALLY SIGNIFICANT OSD (NVS-OSD) VISUALLY SIGNIFICANT OSD (VS-OSD)
(e.g., normal cornea, normal topography/ (e.g., corneal abnormality, central PEE, irregularly irregular
regular astigmatism, no corneal stain, stable vision) astigmatism, abnormal osmolarity, fluctuating vision, etc.)
SURGERY PROCEEDS SURGERY DELAYED
Counsel patient OSD may worsen postoperatively; Refractive measurements unreliable;
start prophylactic treatment identify all OSD subtypes
EXPOSURE/LID MALPOSITION DRY EYE DISEASE LUMPS & BUMPS CONJUNCTIVITIS
(e.g., lagophthalmos, floppy eyelid) EDE (MGD) > ADDE (e.g., EBMD) (e.g., allergic, infectious)
OPTIONAL INVASIVE REFRACTIVE TESTS
(e.g., immersion and/or contact A, B scans, etc.)
Finalized refractive surgical plan (e.g., IOL, LRI, LVC, etc.) TREATMENT PLAN
Based on subtype and severity of each OSD;
combined medical and procedural interventions
NEXT VISIT IS SURGERY ONCE VS-OSD IS Next office visit in 2–4 weeks;
CONVERTED TO NVS-OSD start at beginning of algorithm.
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This activity has been approved for AMA PRA Category 1 CreditTM.