🧠 NCLEX STUDY GUIDE (HIGH-YIELD
ONLY)
Below is what NCLEX actually tests, not textbook overload.
🫁 RESPIRATORY / CARDIAC / CRITICAL CARE
Compensated vs Uncompensated ABGs
Compensated: pH normal, PaCO₂/HCO₃ abnormal
Uncompensated: pH abnormal, only one value abnormal
Priority: Treat the cause, not the numbers
Cardiogenic Shock
↓ CO, ↑ SVR, pulmonary edema
Priority: Oxygen, diuretics, inotropes (dobutamine), vasopressors
No large fluid boluses
Sepsis
SIRS + infection
Early: fever, tachycardia
Late: hypotension, ↓ urine output
Priority: Blood cultures → antibiotics → fluids → vasopressors
Mechanically Ventilated Patient
Prevent VAP: HOB 30–45°
Sedation vacations
Watch for high-pressure alarms = secretions/kinked tube
GI & NUTRITION
Peptic Ulcer vs GERD
Ulcer: epigastric pain, bleeding risk
GERD: heartburn worse after meals/lying down
No NSAIDs for ulcers
Enteral Feeding (NGT/PEG)
Verify placement
Residuals per facility
HOB up during & after feeds
IBD
UC Crohn’s
Colon only Anywhere mouth→anus
Bloody diarrhea Non-bloody
Continuous Skip lesions
Ostomy Care
Stoma should be pink/red
No nerve endings → no pain
Measure output
Liver Dysfunction
Ascites: diuretics, paracentesis
Encephalopathy: lactulose
Cirrhosis: bleeding risk
Esophageal Varices
Risk of rupture
No NG tubes
Octreotide, beta blockers
Pancreatitis
NPO
Pain control
Watch calcium (↓)
🧠 NEURO
Neuro Assessment
LOC = most sensitive indicator
GCS < 8 = intubate
Increased ICP
HOB 30°
Avoid coughing, suction only if needed
Watch Cushing’s triad
Seizures
Protect airway
Turn patient on side
Do NOT restrain
Stroke (CVA)
CT before tPA
tPA window: ≤4.5 hrs
Swallow evaluation before oral intake
TBI / SCI
TBI: watch ICP
SCI: autonomic dysreflexia (HTN, headache)
Log roll
Neuro Diseases
MS: heat intolerance
Myasthenia gravis: improves with rest
Parkinson’s: shuffling gait, tremor
Meningitis: droplet precautions
🦴 MUSCULOSKELETAL
Fractures & Joint Replacement
Neurovascular checks (5 Ps)
Prevent DVT
No hip flexion > 90° after THR
Traction
Weights hang freely
No adjustments by nurse
Osteomyelitis
Long-term IV antibiotics
Amputation
Pain control
Prevent contractures
Phantom pain is real
🔥 BURNS / EMERGENCY / EENT
Burn Phases
1. Emergent: fluids (Parkland)
2. Acute: infection risk
3. Rehab: nutrition, mobility
Burn Depth
Superficial → Full thickness
Complications
Hypovolemia
Infection
Electrolyte shifts
Primary vs Secondary Survey
Primary: ABCDE
Secondary: head-to-toe
Eyes & Ears
Glaucoma: ↑ IOP
Cataracts: cloudy lens
Post-eye surgery: no bending/straining
🍺 ALCOHOL & DRUG WITHDRAWAL
Alcohol: benzos
Opioids: supportive care
DTs: medical emergency
🧮 MATH YOU MUST MASTER
Burn fluid (Parkland)
tPA dosing
Reconstitution
Basic dosage calculations
💊 MEDICATIONS (NCLEX PEARLS)
Medication Key Point
Methotrexate Immunosuppression
Phenytoin Gingival hyperplasia
Levetiracetam Mood changes
PPIs ↓ acid
H2 blockers Less potent than PPIs
Prokinetics ↑ GI motility
Norepinephrine Vasopressor
Levodopa Improves movement
Pyridostigmine MG treatment