VISVESVARAYA TECHNOLOGICAL UNIVERSITY
BELAGAVI - 590 018, KARNATAKA.
PROJECT REPORT
(BCG785)
ON
“AI Driven Drug Repurposing:
Unlocking new Therapeutics for existing drugs”
Submitted in the partial fulfilment of requirements for the award of
the degree
In
Department of Computer Science and Design
Submitted by
AISHWARY U P 4BD22CG002
PRAVEEN KUMAR J S 4BD22CG021
SHAHID HABEEB KHAN 4BD22CG030
SNEHA KADEMANI 4BD22CG035
Under The Guidance Of
Prof. MADHURI
DEEKSHITH B.E, [Link],
Department of CS&D.
2025-2026
Department of Computer Science and Design
Bapuji Institute of Engineering & Technology
Davanagere- 577004
VISVESVARAYA TECHNOLOGICAL UNIVERSITY
BELAGAVI - 590 018, KARNATAKA.
BAPUJI INSTITUTE OF ENGINEERING AND TECHNOLOGY
DAVANGERE – 577004, KARNATAKA, INDIA.
Department of Computer Science and Design
CERTIFICATE
This is to Certified that Ms. Aishwarya U P, USN:4BD22CG002, Mr. Praveen Kumar J S,
USN: 4BD22CG021, Mr. Shahidh Habeeb Khan, USN: 4BD22CG030, [Link]
Kademani, USN: 4BD22CG035, respectively of Computer Science and Design department
have satisfactorily submitted the Final Year Project Work report entitled “AI Driven Drug
Repurposing: Unlocking new Therapeutics for exsisting drugs” in the partial fulfilment of
the requirements for the award of Degree of Bachelor of Engineering in Computer Science
Science and Design, under the VTU during the academic year 2025-26. The project report has
been approved, as it satisfies the academic requirements for the year 2025-26.
__________________________
Prof. Madhuri Deekshith B.E, [Link],
Professor, Dept. of CS&D.
Project Guide
____________________ ____________________ ______________________
Dr. Sreenivasa B R, Ph.D. Dr. Chetana Prakash, Ph.D. Dr. H B Aravind Ph.D.
Professor, Professor and Principal
Dept. of CS&D. Program Coordinator,
Project Coordinator Dept. of CS&D.
Date:
Place: Davanagere
ACKNOWLEDGEMENT
We extend our heartfelt gratitude to Bapuji Institute of Engineering and Technology for
providing an exceptional learning environment, well-equipped laboratories, and access to highly
knowledgeable faculty. The support and resources offered by the institute have been
instrumental in the successful completion of this project.
We are deeply indebted to our guide, Prof. Madhuri Deekshith, for his/her unwavering
guidance, insightful feedback, and continuous encouragement throughout this project. His /
Her guidence has been invaluable and has significantly shaped the direction and outcome of our
project work.
Our sincere thanks go to Dr. Sreenivasa B R, the Project Coordinator, for his steadfast support
and expert advice, which consistently helped us navigate challenges confidently. His leadership
and commitment have played a pivotal role in the success of our project.
We would also like to express our profound appreciation to Dr. Chetana Prakash, Program
Coordinator of the Department of Computer Science and Design, whose assistance, valuable
suggestions, and motivating words were crucial in executing this project.
Our gratitude also extends to our beloved Principal, [Link] H B, and
Prof. Y. Vrushabhendrappa, the Director, for their inspiring leadership and moral support,
which encouraged us to strive for excellence.
We are equally thankful to all the faculty members of the Department of Computer Science
and Design for their constant support, constructive feedback, and willingness to assist us
whenever needed. Their guidance has enhanced our understanding and shaped our work in
meaningful ways.
Lastly, we are deeply grateful to our families and friends, whose encouragement, patience, and
unwavering support gave us the strength to complete this project. Their belief in our capabilities
has been a source of constant motivation.
Aishwarya U P [4BD22CG003]
Praveen Kumar J S [4BD22CG019]
ShahidhHabeeb Khan [4BD22CG020]
Sneha Kademani [4BD22CG031]
Bapuji Institute of Engineering and Technology
Davanagere-577004
Department of Computer Science and Design
VISION OF THE DEPARTMENT
“To be a global leader in Computer Science and Design Engineering education and research,
fostering innovation and societal impact through interdisciplinary collaboration and
technological excellence.”
MISSION OF THE DEPARTMENT
M1: To educate and inspire the next generation of computer engineers through rigorous in
academic programs.
M2: To conduct cutting-edge research that drives technological innovation and addresses global
challenges.
M3: To engage in interdisciplinary collaboration, bridging technology and other fields to create
holistic solutions.
M4: To contribute to society by translating research into practical, ethical, and sustainable
technological advancements.
PROGRAM SPECIFIC OUTCOMES (PSOS):
PSO1: Design and develop software and hardware solutions, meeting industry standards and
adapting to evolving technological landscapes.
PSO2: Analyse and address complex engineering problems, and to design and develop
interdisciplinary and innovative systems.
PSO3: Inculcate effective communication skills, teamwork, ethics, and leadership in preparation
for a Successful career in industry and R&D organizations.
Program Educational Objectives (PEOS):
PEO1: Capable of adapting to dynamic technology, fostering innovation, and excelling in the
computer science and design engineering industry.
PEO2: Prepare for advanced studies and research, enabling them to contribute to cutting-edge
knowledge and emerging technologies.
PEO3: Cultivate ethical professionals who communicate effectively, collaborate in diverse
teams, and address complex problems with societal impact.
PEO4: Empower with leadership skills, social responsibility, and a global perspective,
enabling them to make positive contributions to society.
Program Outcomes
PO1: Engineering Knowledge: Apply the knowledge of mathematics, science, engineering
fundamentals, and an engineering specialization to the solution of complex engineering
problems.
PO2: Problem Analysis: Identify, formulate, review research literature, and analyze complex
engineering problems reaching substantiated conclusions using first principles of
mathematics, natural sciences, and engineering sciences.
PO3: Design/Development of Solutions: Design solutions for complex engineering
problems and design system components or processes that meet the specified needs with
appropriate consideration for public health and safety, and cultural, societal, and
environmental considerations.
PO4: Conduct Investigations of Complex Problems: Use research-based knowledge and
research methods, including design of experiments, analysis and interpretation of data, and
synthesis of the information to provide valid conclusions.
PO5: Engineering Tool Usage: Create, select, apply, and adapt appropriate techniques,
resources, and modern engineering and IT tools, including prediction and modeling, to
complex engineering activities, with an understanding of the limitations.
PO6: The Engineer and The World: Apply reasoning informed by contextual knowledge to
assess societal, health, safety, legal, and cultural issues and the consequent responsibilities
relevant to professional engineering practice and demonstrate knowledge of and need for
sustainable development.
PO7: Ethics: Apply ethical principles and commit to professional ethics, responsibilities, and
norms of engineering practice, including diversity and inclusive behavior.
PO8: Individual and Collaborative Team Work: Function effectively as an individual, and
as a member or leader in diverse teams and in multidisciplinary settings.
PO9: Communication: Communicate effectively on complex engineering activities with the
engineering community and with society at large, such as being able to comprehend and write
effective reports and design documentation, make effective presentations, and give and
receive clear instructions, focusing on inclusive and effective communication.
PO10: Project Management and Finance: Demonstrate knowledge and understanding of
engineering and management principles and apply these to one’s own work, as a member and
leader in a team, to manage projects and in multidisciplinary environments.
PO11: Life-Long Learning: Recognize the need for, and have the preparation and ability to
engage in independent and life-long learning in the broadest context of technological change,
including adaptability and tech awareness.
DECLARATION
Ms. Aishwarya U P, USN:4BD22CG002, Mr. Praveen Kumar J S, USN: 4BD22CG021
Mr. Shahidh Habeeb Khan, USN: 4BD22CG030, Ms. Sneha Kademani, USN:
4BD22CG035, students of B.E in Computer Science and Design, Bapuji Institute of
Engineering and Technology, Davanagere, hereby declare that the Project Report submitted
to the Visvesvaraya Technological University during the academic year 2024-2025 is
record of an original done by me under the guidance of Prof. Madhuri Deekshith
Department of Computer Science and Design, Bapuji Institute of Engineering and
Technology Davanagere. This work is submitted in partial fulfillment of the requirements
for the award of the degree of Bachelor of Engineering in Computer Science and Design. The
results embodied in this report have not been submitted to any other university or institute
for any degree.
Aishwarya U P [4BD22CG002]
Praveen Kumar J S [4BD22CG021]
ShahidhHabeeb Khan [4BD22CG030]
Sneha Kademani [4BD22CG035]
ABSTRACT
AI-based drug repurposing is an emerging approach that uses advanced computational techniques to
discover new therapeutic uses for existing drugs. It speeds up drug discovery by rapidly analyzing large
biomedical datasets such as gene expression profiles, chemical structures, and disease pathways. Using
machine learning and deep learning models, AI uncovers hidden patterns and predicts which approved
drugs could be effective for new diseases. Since the safety and toxicity of these drugs are already known,
repurposing greatly reduces both cost and development time. AI also combines clinical, genomic, and
pharmacological data to improve prediction accuracy, enabling faster screening and better decision-
making. Overall, AI-driven drug repurposing provides a powerful, cost-effective, and efficient strategy
for modern therapeutics and rapid response to emerging diseases.
CONTENTS
[Link] Title Page No.
1 INTRODUCTION 1-3
1.1 Background of the project 1
1.2 Problem Domain 1
1.3 Motivation 2-3
1.4 Scope of the Project 3
2 LITERATURE REVIEW 4-11
2.1 Review of Existing Research 4-7
2.2 Comparative Study Table 8
2.3 Research Gap Identification 9
2.4 Summary of Literature Review 9
2.5 Existing system 10
2.6 Problem statement 10
2.7 Proposed system 10
2.8 Objectives of the Project 11
3 SYSTEM REQUIREMENT SPECIFICATION 12-14
3.1 Hardware Requirements 12
3.2 Software Requirements 12
3.3 Functional Requirements 12-13
3.4 Non-Functional Requirements 13-14
4 SYSTEM DESIGN 15-16
4.1 Block Diagram 15
4.2 Usecase Diagram 16
4.3 Class Diagram 17
4.4 Sequence Diagram 18
4.5 ER Schema Diagram 19
5 METHODOLOGY 20- 46
5.1 Pseudocode 20-23
5.2 Implementation 24-49
6 SYSTEM TESTING 50
7 RESULTS AND DISCUSSION 51-54
7.1 Screenshots 51-52
7.2 Performance Evaluation 53
7.3 Comparison Graphs 54
7.4 Limitations 54
8 CONCLUSION
9 FUTURE ENHANCEMENT
10 REFERENCE