INTERNSHIP REPORT

Submitted to: Krupanidhi College of

Pharmacy Internship Organization: EISEN
Pharmaceuticals Co Pvt Ltd. Pune

Internship Duration: 1st December 2025 –

31st December 2025
Intern Name: SUDEEP KASHINATH
JADHAV
Course: Bachelor of Pharmacy VII sem.
The first day of my internship began with a formal orientation session. The
training supervisor introduced us to the company’s mission, vision, and
product portfolio, which includes tablets, syrups, and veterinary formulations.
A strong emphasis was placed on safety measures, which are the
foundation of pharmaceutical manufacturing.

We were taught about personal protective equipment (PPE) such as lab

coats, gloves, masks, and hairnets, which are mandatory in production areas.
Hygiene protocols were explained, including hand sanitization, restricted
access zones, and contamination control.

The session then moved to Standard Operating Procedures (SOPs).

SOPs are written documents that define how routine operations should be
performed. I learned that SOPs ensure consistency, reduce errors, and

provide a reference for training new employees. We were shown how SOPs
are maintained, updated, and approved, with signatures from supervisors to
validate compliance.

Finally, we were introduced to Good Manufacturing Practices (GMP).

GMP is a regulatory framework that ensures medicines are consistently
produced and controlled according to quality standards. The importance of
GMP was stressed, as it directly impacts patient safety.

Reflection: Day one gave me a strong foundation in understanding the

ethical and regulatory responsibilities of the industry. Before touching
machines or formulations, one must first respect safety, documentation, and
compliance

Day 2: Tablet Department – Equipment Observation and Packaging

On the second day, I was assigned to the tablet department, where I

observed the equipment used in tablet manufacturing. Machines such as
granulators, blenders, compression units, and coating machines
were explained in detail. Supervisors demonstrated how each machine is
cleaned, calibrated, and operated.

I learned that granulation is the process of forming granules to ensure

uniform distribution of the drug and excipients. Blenders mix the granules to
achieve homogeneity, while compression machines apply force through
punches and dies to form tablets. Coating machines are used to apply
protective or functional layers to tablets.
Later, I participated in the packaging of Ultrafolin MBA tablets.
Packaging is a critical step in ensuring product stability and patient
compliance. I observed blister packaging and bottle filling processes. Each
package was labeled with batch numbers, manufacturing dates, and expiry
dates. Supervisors emphasized the importance of traceability, which allows
defective batches to be recalled if necessary.

Reflection: Observing the equipment gave me a practical understanding of

how theoretical concepts like granulation and compression are applied.
Packaging taught me the importance of accuracy and attention to detail, as
even a small labeling error can have serious consequences.

Day 3: Tablet Compression and Quality Control Tests

Day three was one of the most engaging experiences. I observed the tablet
compression process using a rotary compression machine. The principle of
compression involves applying force through punches and dies to convert
granules into solid tablets. Uniform compression ensures consistent dosage
and mechanical strength.

We then performed several quality control (QC) tests:

 Weight Variation Test: Ensures each tablet contains the correct drug
amount.

 Dissolution Test: Measures how quickly the drug dissolves, ensuring

bioavailability.

 Friability Test: Assesses mechanical strength by rotating tablets and

checking for breakage.

 Thickness Measurement: Ensures uniformity for packaging and

patient compliance.

Each test was explained in detail, and I understood their significance in

maintaining pharmacopeial standards. For example, the dissolution test
ensures that the drug will release properly in the body, while friability
ensures tablets can withstand handling during transport.

Reflection: This day connected my classroom knowledge of pharmaceutics

with real industrial practice. I realized that QC tests are not just routine
checks but safeguards for patient health.

Day 4: Packaging of Ultrafolin Tablets

On the fourth day, I returned to the packaging section, focusing again on
Ultrafolin tablets. I observed the workflow of packaging lines, including bottle
filling, sealing, labeling, and final inspection. Supervisors emphasized the
importance of batch documentation and cross-checking labels to prevent
errors.

I learned that packaging is not merely a mechanical process but a critical

stage in ensuring medicine reaches patients safely. Proper packaging
protects the product from environmental factors such as moisture, light, and
contamination. It also ensures patient compliance by providing clear
instructions and dosage information.

Reflection: Packaging may seem repetitive, but it is a vital step in the

pharmaceutical supply chain. I realized that packaging is as important as
production, as it directly affects patient trust and compliance.

Day 5: Production of Cold Guard 500 mg Tablets

On the fifth day, I was assigned to the production of Cold Guard 500 mg
tablets. This involved observing the granulation process, where excipients
and active pharmaceutical ingredients (APIs) were mixed to form granules.
The granules were then dried to remove moisture, compressed into tablets,
and prepared for packaging.

I learned that each step in tablet production must be carefully monitored.

Granulation ensures uniform distribution of the drug, drying improves
stability, and compression determines tablet strength. Supervisors explained
the importance of in-process quality checks, such as monitoring granule
size and moisture content.

Reflection: This day highlighted the complexity of tablet production. I

realized that producing a single tablet involves multiple steps, each requiring
precision and compliance with SOPs.

Day 6: Packaging of Cold Guard 500 mg Tablets

On the sixth day, I was again assigned to the packaging section, this time
focusing on Cold Guard 500 mg tablets. I observed the sealing of bottles,
labeling, and inspection processes. Supervisors explained the importance of
packaging integrity, as damaged seals or incorrect labels can compromise
patient safety.
Reflection: Packaging may appear routine, but it is a critical safeguard. I
learned that packaging ensures product stability, compliance, and patient
trust.

Day 7: Production of Constac Tablets and Capsule Filling

On the seventh day, I was assigned to the production department for the
manufacturing of Constac tablets. The process began with granulation,
where the active pharmaceutical ingredient (API) and excipients were
blended to form granules. Granulation improves flow properties and ensures
uniform drug distribution.

After granulation, the material was transferred to the compression

machine, where tablets were formed using punches and dies. I observed
how compression pressure and machine speed directly affect tablet hardness
and uniformity. The tablets were then subjected to drying, which removes
residual moisture and enhances stability. Finally, the tablets were packaged
into bottles, with batch numbers and expiry dates carefully recorded.

In addition to tablet production, I was introduced to Pantoprazole DSR

capsule filling and packaging. Capsule filling involves dosing the drug
into hard gelatin shells using automated machines. The importance of
uniform fill weight and sealing was emphasized.

Reflection: This day gave me exposure to both tablet and capsule

manufacturing. I realized that while tablets and capsules are different dosage
forms, both require strict adherence to SOPs and GMP to ensure patient
safety.

Day 8: Production of Constac Plus Tablets

On the eighth day, I was assigned to the production of Constac Plus tablets.
The focus was on granulation, a critical step in tablet manufacturing. I
observed the use of wet granulation, where binding agents were added to
improve cohesion of powder particles.

The granules were dried and sieved to achieve uniform particle size.
Supervisors explained that granulation not only improves flow properties but
also ensures dose accuracy.

Reflection: I learned that granulation is the backbone of tablet

manufacturing. Without proper granulation, tablets may show weight
variation, poor dissolution, or friability issues.

Day 9: Granule Filling and Bottle Packaging

On the ninth day, I observed granule filling into laminated pouches and
tablet filling into bottles. Laminated pouches are used to protect granules
from moisture and contamination. The sealing process was demonstrated,
ensuring airtight packaging.

Tablet filling into bottles was carried out using automated lines. Each bottle
was labeled with batch details, and quality checks were performed to ensure
correct counts.

Reflection: Packaging is not just about aesthetics; it is a protective barrier

that ensures medicine reaches patients safely.

ay 10: Production of Cold Guard Pediatric Syrup

On the tenth day, I was assigned to the liquid department for the
production of Cold Guard Pediatric Syrup. The process involved dissolving
APIs in a suitable solvent, followed by mixing with excipients such as
sweeteners, flavoring agents, and preservatives.

The syrup was homogenized to ensure uniform distribution of ingredients.

Filtration was performed to remove particulate matter. The final product was
filled into bottles under hygienic conditions.

Reflection: Syrup production taught me the importance of uniform mixing

and filtration. Pediatric formulations require extra care, as they are
administered to children.

Day 11: Syrup Filling and Packaging

On the eleventh day, I participated in filling Cold Guard syrup into

bottles. Automated filling machines ensured accurate volume per bottle.
The bottles were sealed, labeled, and packaged into cartons.

Supervisors emphasized the importance of hygiene and sterility in liquid

packaging, as contamination can compromise product safety.

Reflection: I realized that packaging liquids requires more precision than

solids, as even minor contamination can affect product quality.

Day 12: Production of Sayfer Syrup

On the twelfth day, I was assigned to the production of Sayfer Syrup. The
process involved mixing APIs with excipients in large stainless-steel tanks.
The mixture was stirred continuously to achieve homogeneity.
Supervisors explained the role of stabilizers and preservatives in maintaining
syrup stability.

Reflection: I learned that excipient selection is crucial in liquid formulations.

Each excipient plays a role in taste, stability, and patient compliance.

Day 13: Bottle Filling and Packaging of Sayfer Syrup

On the thirteenth day, I participated in bottle filling and packaging of

Sayfer Syrup. The bottles were filled using automated machines, sealed
with caps, and labeled. Batch documentation was completed to ensure
traceability.

Reflection: Documentation is as important as production. Without proper

records, it is impossible to trace errors or recall defective batches.

Day 14: Production of Kesol Fovet Suspension

On the fourteenth day, I observed the production of Kesol Fovet Suspension,

a veterinary formulation. Suspensions are different from syrups, as they
contain insoluble particles dispersed in a liquid medium.

The process involved mixing APIs with suspending agents to prevent

sedimentation. Homogenization was performed to achieve uniform particle
distribution.

Reflection: Veterinary formulations require the same precision as human

medicines. I realized that GMP applies universally across all dosage forms.

Day 15: Packaging of Kesol Fovet Suspension

On the fifteenth day, I participated in packaging Kesol Fovet Suspension.

Bottles were filled, sealed, and labeled. Supervisors explained the
importance of shake-well labels on suspensions, as particles tend to settle.

Reflection: Packaging must communicate instructions clearly to patients.

Labels are not just identifiers but guides for safe medicine use.

Day 16: Production of Appelite Syrup

On the sixteenth day, I was assigned to the liquid formulation

department for the production of Appelite Syrup. The process began with
the preparation of the base solution, where excipients such as sweeteners,
flavoring agents, and stabilizers were dissolved in purified water. The active
pharmaceutical ingredient (API) was then carefully weighed and added to the
solution under continuous stirring.
Supervisors explained the importance of mixing speed and duration, as
improper mixing can lead to uneven distribution of the drug. The solution
was homogenized to ensure uniformity and filtered to remove particulate
matter. I observed how stainless-steel mixing tanks are designed to prevent
contamination and maintain sterility.

Reflection: This day taught me that liquid formulations require meticulous

control of mixing and homogenization. Unlike tablets, syrups must maintain
uniformity throughout the solution to ensure accurate dosing for patients.

Day 17: Packaging of Appelite Syrup

On the seventeenth day, I participated in the packaging of Appelite

Syrup. The syrup was filled into bottles using automated filling machines,
which ensured precise volume per bottle. Each bottle was sealed with
tamper-proof caps and labeled with batch numbers, manufacturing dates,
and expiry dates.

Supervisors emphasized the importance of packaging integrity. Any

leakage or improper sealing could compromise product quality. I also learned
about secondary packaging, where bottles are packed into cartons for
distribution.

Reflection: Packaging liquids requires strict hygiene and accuracy. I realized

that packaging is not just about enclosing the product but about protecting it
from contamination and ensuring patient safety.

Day 18: Production of Anoac-H Tablets

On the eighteenth day, I was assigned to the tablet production

department for the manufacturing of Anoac-H tablets. The process involved
granulation, where powders were blended with binding agents to form
granules. The granules were dried, sieved, and compressed into tablets using
a rotary compression machine.

Supervisors explained the importance of compression force and punch

design, which affect tablet hardness and disintegration time. I observed
in-process checks such as monitoring tablet weight and thickness.

Reflection: This day reinforced the importance of precision in tablet

manufacturing. Even small deviations in compression parameters can affect
tablet quality and therapeutic efficacy.

Day 19: Packaging of Anoac-H Tablets and Production of Acideem

Plus Tablets
On the nineteenth day, I was involved in two tasks. First, I participated in the
packaging of Anoac-H tablets, where tablets were filled into bottles,
sealed, and labeled. Supervisors emphasized the importance of batch
documentation and cross-checking labels.

Later, I observed the production of Acideem Plus tablets. The process

involved granulation, drying, and compression. I learned about the role of
excipients such as disintegrants and lubricants in tablet formulation.

Reflection: This day highlighted the multitasking nature of pharmaceutical

production. I realized that production and packaging often run
simultaneously, requiring coordination and attention to detail.

Day 20: Packaging of Acideem Plus Tablets

On the twentieth day, I was assigned to the packaging of Acideem Plus

tablets. The tablets were filled into bottles using automated lines. Each
bottle was sealed, labeled, and packed into cartons. Supervisors explained
the importance of label accuracy, as incorrect labeling can lead to serious
consequences.

Reflection: Packaging may seem repetitive, but it is a critical safeguard. I

learned that packaging ensures product stability, compliance, and patient
trust.

Day 21: Continued Packaging of Acideem Plus Tablets

On the twenty-first day, I continued with the packaging of Acideem Plus

tablets. The focus was on maintaining consistency and accuracy throughout
the process. Supervisors emphasized the importance of quality checks,
where random samples were inspected for correct labeling and sealing.

Reflection: Repetition in packaging taught me the value of consistency. I

realized that pharmaceutical manufacturing is not just about innovation but
also about maintaining high standards every single day.

Day 22: Introduction to Quality Assurance (QA)

On the twenty-second day, I was assigned to the Quality Assurance

department. This marked a shift from production and packaging to the
documentation and compliance side of pharmaceutical manufacturing.
Supervisors explained the importance of QA in medicine production,
emphasizing that QA is not about testing products but about ensuring that
every step of production follows GMP and SOPs.
I learned that QA involves monitoring processes, verifying documentation,
and ensuring that deviations are recorded and corrected. Supervisors
showed us how batch records are maintained, how SOPs are cross-checked,
and how audits are prepared.

Reflection: This day taught me that QA is the backbone of pharmaceutical

manufacturing. Without proper QA, even well-produced medicines cannot be
released to the market. Documentation is as important as the product itself.

Day 23: Error Findings in QA Documentation

On the twenty-third day, I continued in the QA department, focusing on

error findings in documents. Supervisors explained that documentation
errors can occur in batch records, SOPs, or production logs. My task was to
identify inconsistencies, missing signatures, or incorrect entries.

I observed how QA staff carefully review documents line by line. Any error,
no matter how small, must be corrected and signed off by supervisors. This
ensures traceability and accountability.

Reflection: I realized that QA requires patience, attention to detail, and

discipline. Unlike production, where the focus is on machines and
formulations, QA is about paperwork and compliance. Yet, it is equally critical
for patient safety.

Day 24: Documentation, Supervisor Signatures, and Final QA Checks

On the final day of my internship, I was again assigned to the QA

department. My tasks included error correction, obtaining supervisor
signatures, and ensuring proper documentation. I learned how
corrected documents are archived for future reference and how QA ensures
that every batch can be traced back to its origin.

Supervisors explained that documentation is not just for internal use but also
for regulatory audits. Inspectors from agencies like the FDA or local drug
authorities rely on QA records to verify compliance.

Reflection: Ending my internship in QA gave me a holistic view of

pharmaceutical manufacturing. I realized that production, packaging, and QA
are interconnected. Without QA, the entire system would collapse.

Overall Skills Acquired

 Practical knowledge of tablet and syrup production.

 Hands-on experience with packaging processes.

 Conducting quality control tests (weight variation, dissolution,
friability, thickness).

 Exposure to QA documentation and compliance.

 Improved teamwork, communication, and time management.

 Stronger attention to detail and professional ethics.

 Reflection & Analysis

 This internship bridged the gap between academic learning and industrial practice. I
gained exposure to multiple departments, from production to QA. I understood the
importance of GMP, SOPs, and documentation in ensuring patient safety. Personally, I
developed confidence, discipline, and problem-solving skills. Professionally, I gained
insights into pharmaceutical manufacturing that will guide my career.
 Conclusion
 My internship at EISEN Pharmaceuticals Co Pvt Ltd was a transformative experience.
It provided practical exposure to pharmaceutical production, packaging, and quality
assurance. The knowledge and skills acquired will serve as a strong foundation for my
career in pharmacy.