Overview of the Nervous System Functions
Overview of the Nervous System Functions
Function
- The nervous system coordinates and controls body functions. It
receives sensory input, makes decisions, and then orders body
responses.
Organs
- Spinal Cord, brain, nerves
Word Roots
alges sense of pain
astr star
centr center
cerebell cerebellum
cerebr cerebrum
encephal brain
mening meninges
meningi meninges
ment mind
neur nerve
pont pons
thalam thalamus
tom to cut
ton tone
ventricul ventricle
hydro water
angi vessel
arteri artery
cephal head
crani skull
cutane skin
cyt cell
electr electricity
gli glue
hal to breathe
hemat blood
later side
my muscle
scler hard
spin spine
topic a specific area
ven vein
vertebr vertebra
Suffixes
-paresis weakness
-phasia speech
-oid resembling
-asthenia weakness
-cele protrusion
-algia pain
-gram record
-ion action
-itis inflammation
-logy study of
-pathy disease
-plegia paralysis
-rrhaphy suture
-al pertaining to
-ar
-ary
-eal
-ic
-ical
-ine
-ous
-tic
Prefixes
a- without
an- without
anti- against
bi- two
de- without
endo- within
epi- above
hemi- half
hyper- excessive
in- inward
intra- within
mono- one
poly- many
quadri- four
semi- partial
sub- under
trans- across
tri- three
un- not
Functions
Brain
- Coordinates body functions
Spinal Cord
- Transmits messages to and from the brain
Nerves
- Transmit messages to and from the central nervous system
To coordinate all activity of the body, it must first receive information from
the internal and external sensory receptors and then use that information to
adjust the activity of muscles and glands to match the needs of the body.
The nervous system can be divided into the;
- central nervous system (CNS)
- peripheral nervous system (PNS)
Nervous Tissue
Nervous tissue is made of:
- Neurons
- Neuroglial cells
Neurons
- Individual nerve cells.
- Capable of conducting electrical impulse in response to a stimulus
Dendrites
- Highly branched projections that receive impulses
Axon
- Projection from the nerve cell body that conducts the electrical impulse
toward its destination
● The point at which the axon of one neuron meets the dendrite of the
next neuron is called a synapse (comes from the Greek word meaning
connection)
● Electrical impulses cannot pass directly across the gap between two
neurons, this is called the synaptic cleft
- They require the help of a chemical messenger, called a
neurotransmitter
● Many different neuroglial cells are found in the nervous tissue. Each of
them have a different function
- Some neuroglial cells produce myelin (a fatty substance that
acts as insulation for many axons so they can conduct electrical impulses
faster)
Gray matter
- Comprised of unsheathed or uncovered cell bodies and dendrites
White matter
- Myelinated nerve fibers
- The myelin sheath makes the nervous tissue appear white
*Myelin is a lipid and a very white molecule which is why myelinated
neurons are called white matter
Tracts
- Bundles of nerve fibers interconnecting different parts of the central
nervous system
Meninges
- Three membranes that encase and protect the central nervous system
Brain
One of the largest organs of the body and coordinates most body activities.
Center of:
- Thought
- Memory
- Judgment
- Emotion
Each part of the brain controls different body functions (temperature
regulation, blood pressure, and breathing)
The largest section of the brain is the cerebrum, located in the upper portion
The elevated portions of the cerebrum, or convolutions, are called gyri and
are separated by fissures, or valleys, called sulci.
The cerebrum is subdivided into left and right halves called cerebral
hemispheres
- Each hemisphere has four lobes.
The diencephalon, located below the cerebrum, contains two of the most
critical areas of the brain, the thalamus and the hypothalamus
Thalamus
- Composed of gray matter
- Acts as a center for relaying impulses from the eyes, ears, and skin to
the cerebrum
- Controls pain perception
Hypothalamus
- Just below the thalamus
- Controls body temp, appetite, sleep, sexual desire, and emotions
- Responsible for controlling the autonomic nervous system,
cardiovascular system, digestive system, and the release of hormones
from the pituitary gland
Cerebellum
- Second largest portion of the brain
- Located beneath the posterior part of the cerebrum
- Aids in coordinating voluntary body movements and maintaining
balance and equilibrium
- Refines the muscular movement that is initiated in the cerebrum
The brainstem has three components:
- Midbrain
- Pons
- Medulla Oblongata
Midbrain
- Pathway for impulses to be conducted between the brain and the spinal
cord
Pons
- A term that means “bridge”
- Connects the cerebellum to the rest of the brain
Medulla Oblongata
- Most inferior positioned portion of the brain
- Connects the brain to the spinal cord
- Contains the centers that control respiration, heart rate, temperature,
and blood pressure
- Nerve tracts cross from one side of the brain to control functions and
movement on the other side of the body
The left side of the brain controls the right side of the brain and vice versa
The 33 vertebrae of the backbone line up to form a continuous canal for the
spinal cord called the spinal cavity or vertebral canal
*Some disease processes attack the gry and white matter of the central
nervous system. For example, poliomyelitis is a viral infection of the gray
matter of the spinal cord.
Just like the brain, the spinal cord is also protected by cerebrospinal fluid.
- Flows down the center of the spinal cord with the central canal
- The inner cord consists of cell bodies and dendrites of peripheral nerves
and therefore is gray matter
- The outer portion of the spinal cord is myelinated white matter
- The white matter is either ascending tracts carrying sensory
information up to the brain or descending tracts carrying motor
commands down from the brain to a peripheral nerve
Meninges
The meninges are three layers of connective tissue membranes
surrounding the brain and spinal cord. From external to internal, the
meninges are:
Dura Mater
- Meaning tough mother; it forms a tough, fibrous sac around the central
nervous system
Subdural Space
- Actual space between the dura mater and arachnoid layer
Arachnoid Layer
- Meaning spiderlike; it’s a thin, delicate layer attached to the pia mater
by weblike filaments
Subarachnoid Space
- Space between the arachnoid layer and the pia mater; it contains
cerebrospinal fluid that cushions the brain from the outside
Pia mater
- Meaning soft mother; it’s the innermost membrane layer and is applied
directly to the surface of the brain and spinal cord
The PNS include both the 12 pairs of cranial nerves and the 31 pairs of spinal
nerves.
A nerve is a group of axon fibers located outside the CNS that carries
messages between the central nervous system khl7and the various parts of the
body.
Cranial Nerves
*Because nerve tracts cross from one side of the body to the other side of the
brain, damage to one side of the brain results in symptoms appearing on the
opposite side of the body.
Most nerves carry information to and from the central nervous system,
individual neurons carry information in only one direction.
Ganglion
- The nerve cell bodies of the neurons that form the nerve that are
grouped in a knot-like mass; outside the CNS
Sympathetic Nerves
- Controls fight-or-flight reaction during times of stress and crisis
- Increase heart rate, dilate airways, increase blood pressure, inhibit
digestion, and stimulate the production of adrenaline during a crisis
Parasympathetic Nerves
- Serve as a counterbalance for the sympathetic nerves, the rest-and-
digest reaction
- Slow down heart rate, lower blood pressure, and stimulate digestion
Somatic Nerves
Serve the skin and skeletal muscles and are mainly involved with the
conscious and voluntary activities of the body
The large variety of sensory receptors found in the dermis layer of the skin
use somatic nerves to:
- Send their info (to the brain)
- Touch
- Temperature
- Pressure
- Pain
- Carry motor commands to skeletal muscles
Terminology
All under word roots, suffixes, and prefixes
cephalic
Pertaining to head
cerebellar
Pertaining to cerebellum
cerebral
Pertaining to cerebrum
cerebrospinal
Pertaining to cerebrum and spine
cranial
Pertaining to skull
encephalic
Pertaining to brain
intracranial
Pertaining to within the skull
intrathecal
Pertaining to within the meninges (sheath encasing central nervous system),
specifically the subdural or subarachnoid space
medullary
Pertaining to medulla oblongata
meningeal
Pertaining to meninges
myelonic
Pertaining to spinal cord
neural
Pertaining to nerves
neuroglial
Pertaining to glial cells that surround and support neurons
pontine
Pertaining to pons
spinal
Pertaining to spine
subdural
Pertaining to under dura mater
thalamic
Pertaining to thalamus
ventricular
Pertaining to ventricles
vertebral
Pertaining to vertebrae
Pathology
Medical Specialities
anesthesiology
Branch of medicine specializing in all aspects of anesthesia, including for
surgical procedures, resuscitation measures, and management of acute and
chronic pain; physician is anesthesiologist
neurology
Branch of medicine concerned with diagnosis and treatment of diseases and
conditions of the nervous system; physician is neurologist
neurosurgery
Branch of medicine concerned with treating conditions and diseases of the
nervous system by surgical means; physician is neurosurgeon
absence seizure
Type of epileptic seizure that lasts only a few seconds to half a minute,
characterized by loss of awareness and absence of activity; also known as
petit mal seizure
analgesia
Absence of pain
anesthesia
Condition in which there is lack of feeling or sensation
aphasia
Inability to communicate verbally or in writing due to damage of speech or
language centers in the brain
ataxia
Lack of muscle coordination
aura
Sensations, such as seeing colors or smelling an unusual odor, that occur just
prior to epileptic seizure or migraine headache
cephalalgia
Headache (HA)
coma
Profound unconsciousness resulting from illness or injury
conscious
Condition of being awake and aware of surroundings
convulsion
Severe involuntary muscle contractions and relaxations; have a variety of
causes, such as epilepsy, fever, and toxic conditions
delirium
Abnormal mental state characterized by confusion, disorientation, and
agitation
dementia
Progressive impairment of intellectual function that interferes with
performing activities of daily living; patients have little awareness of their
condition; found in disorders such as Alzheimer’s
dysphasia
Difficulty communicating verbally or in writing due to damage of speech or
language centers in the brain
focal seizure
Localized seizure often affecting one limb
hemiparesis
Weakness or loss of motion on one side of the body
hemiplegia
Paralysis on only one side of the body
hyperesthesia
Condition of abnormally heightened sense of feeling, sense of pain, or
sensitivity to touch
monoparesis
Muscle weakness in one limb
monoplegia
Paralysis of one limb
neuralgia
Nerve pain
palsy
Temporary or permanent loss of ability to control movement
paralysis
Temporary or permanent loss of function or voluntary movement
paraplegia
Paralysis of lower portion of the body and both legs (the two like parts of a
pair)
paresthesia
Abnormal sensation such as burning or tingling
quadriplegia
Paralysis of all four limbs
seizure
Sudden, uncontrollable onset of symptoms, such as in epileptic seizure
semiconscious
State of being aware of surroundings and responding to stimuli only part of
the time
syncope
Fainting
tonic-clonic seizure
ton/o = toneclon/o = rapid contracting and relaxing-ic = pertaining to
Type of severe epileptic seizure characterized by loss of consciousness and
convulsions; seizure alternates between strong continuous muscle spasms
(tonic) and rhythmic muscle contraction and relaxation (clonic); also known
as grand mal seizure
tremor
Involuntary, repetitive, alternating movement of a part of the body
unconscious
State of being unaware of surroundings, with the inability to respond to
stimuli
Brain
Alzheimer’s disease (AD)
Chronic, organic mental disorder consisting of dementia, which is more
prevalent in adults after age 65; involves progressive disorientation, apathy,
speech and gait disturbances, and loss of memory; named for German
neurologist Alois Alzheimer
anencephaly
Congenital defect in which portions of the brain (usually the cerebrum) do
not develop; child born with condition is missing a portion of the brain,
cranium, and scalp; condition usually fatal within a few hours of birth
astrocytoma
Tumor of brain or spinal cord composed of astrocytes, one type of neuroglial
cells that has arms projecting off it like a star
brain tumor
Intracranial mass, either benign or malignant; benign tumor of the brain can
still be fatal since it will grow and cause pressure on normal brain tissue
cerebellitis
Inflammation of the cerebellum
cerebral aneurysm
Localized abnormal dilation of blood vessel, usually artery; result of
congenital defect or weakness in wall of vessel; ruptured aneurysm is
common cause of hemorrhagic cerebrovascular accident
cerebral contusion
cerebr/o = cerebrum-al = pertaining to
Bruising of the brain from blow or impact
concussion
Injury to the brain resulting from the brain being shaken inside the skull from
blow or impact; symptoms vary and may include headache, blurred vision,
nausea or vomiting, dizziness, and balance problems; also called mild
traumatic brain injury (TBI)
encephalitis
Inflammation of the brain
epilepsy
Recurrent disorder of the brain in which seizures and loss of consciousness
occur as result of uncontrolled electrical activity of neurons in the brain
hydrocephalus
Accumulation of cerebrospinal fluid within ventricles of the brain, causing
the head to be enlarged; treated by creating artificial shunt for fluid to leave
the brain; if left untreated, may lead to seizures and intellectual disability
migraine
Specific type of headache characterized by severe head pain, sensitivity to
light, dizziness, and nausea
Parkinson’s disease
Chronic disorder of the nervous system with fine tremors, muscular
weakness, rigidity, and shuffling gait; named for British physician James
Parkinson
Reye’s syndrome
Combination of symptoms first recognized by Australian pathologist R. D. K.
Reye that includes acute encephalopathy and damage to various organs,
especially the liver; occurs in children under age 15 who have had a viral
infection; also associated with taking aspirin; for this reason, it’s not
recommended for children to use aspirin
shaken baby syndrome (SBS)
Caused by violent shaking of infant or toddler; symptoms may include
subdural hematoma, brain swelling, and bleeding in retina of the eyes;
usually no evidence of external trauma; also called abusive head trauma
(AHT)
Spinal Cord
amyotrophic lateral sclerosis (ALS)
Condition with muscular weakness and atrophy due to degeneration of motor
neurons of the spinal cord; also called Lou Gehrig’s disease, after New York
Yankees baseball player who died from this disease
meningocele
Congenital condition in which the meninges protrude through opening in the
vertebral column ; see spina bifida
myelitis
Inflammation of the spinal cord
myelomeningocele
Congenital condition in which meninges and spinal cord protrude through
opening in the vertebral column; see spina bifida
poliomyelitis
Viral inflammation of gray matter of the spinal cord; results in varying
degrees of paralysis; may be mild and reversible or may be severe and
permanent; disease has been almost eliminated due to discovery of vaccine in
the 1950s
spina bifida
Congenital defect in walls of the spinal canal in which laminae of the
vertebra do not meet or close ; may result in meningocele or
myelomeningocele—meninges or the spinal cord being pushed through
opening
Nerves
Bell’s palsy
One-sided facial paralysis due to inflammation of facial nerve, probably viral
in nature; patient cannot control salivation, tearing of the eyes, or expression,
but most will eventually recover
Guillain-Barré syndrome
Disease of the nervous system in which nerves lose their myelin covering;
may be caused by autoimmune reaction; characterized by loss of sensation
and/or muscle control starting in the legs; symptoms then move toward trunk
and may even result in paralysis of the diaphragm
myasthenia gravis
Disease with severe muscular weakness and fatigue due to insufficient
neurotransmitter at a synapse
neuroma
Nerve tumor or tumor of connective tissue sheath around a nerve
neuropathy General term for disease or damage to a nerve
polyneuritis
Inflammation of two or more nerves
radiculitis
Inflammation of a nerve root; may be caused by herniated nucleus pulposus
radiculopathy
Refers to condition that occurs when a herniated nucleus pulposus puts
pressure on a nerve root; symptoms include pain and numbness along path of
affected nerve
shingles
Eruption of painful blisters on body along a nerve path caused by Herpes
zoster virus infection of nerve root; virus initially introduced into body during
chickenpox infection but becomes dormant in nerve cells; reactivation of
virus later in life results in shingles
trigeminal neuralgia
Chronic disorder characterized by sudden, sharp pain on one side of face in
area served by the trigeminal cranial nerve; usually caused by pressure on
and irritation of nerve or may be sign of multiple sclerosis; also called tic
douloureux
Meninges
epidural hematoma
Mass of blood in space outside the dura mater of the brain and spinal cord
meningioma
Tumor in the meninges
meningitis
Inflammation of the meninges around brain or spinal cord caused by bacterial
or viral infection; symptoms include fever, headache, neck stiffness, lethargy,
vomiting, irritability, and photophobia
subdural hematoma
Mass of blood forming beneath the dura mater if the meninges are torn by
trauma; may exert fatal pressure on the brain if hematoma not drained by
surgery
Diagnostic Procedures
Clinical Laboratory Tests
cerebrospinal fluid analysis
Laboratory examination of clear, watery, colorless fluid from within brain
and spinal cord; infections and abnormal presence of blood can be detected in
this test
Diagnostic Imaging
brain scan
Image of the brain taken after injection of radioactive isotopes into
circulation
cerebral angiography
X-ray of blood vessels of the brain after injection of radiopaque dye
echoencephalography
Recording of ultrasonic echoes of the brain; useful in determining abnormal
patterns of shifting in the brain
myelogram
X-ray record of the spinal cord
myelography
Injection of radiopaque dye into the spinal canal; X-ray is then taken to
examine normal and abnormal outlines made by dye
lumbar puncture (LP) Puncture with needle into lumbar area (usually fourth
(LUM-bar / PUNK-chur) intervertebral space) to withdraw fluid for examination
and for injection of anesthesia; also called spinal
puncture or spinal tap
Therapeutic Procedures
Anesthesia
anesthesia
Administering medication to produce loss of feeling or sensation
inhalation anesthesia
Route for administering general anesthesia by breathing it in
local anesthesia
Produces loss of sensation in one localized part of body; patient remains
conscious
regional anesthesia
Interrupts patient’s pain sensation in region of body, such as the arm;
anesthetic is injected near nerve that will be blocked from sensation; also
called nerve block
subcutaneous anesthesia
Method of applying local anesthesia involving injecting anesthetic under the
skin; for example, used to deaden skin prior to suturing a laceration
topical anesthesia
Method of applying local anesthesia involving placing liquid or gel directly
onto specific area of skin; for example, used on the skin, cornea, or gums
Medical Procedures
nerve block
Injection of regional anesthetic to stop passage of sensory or pain impulses
along a nerve path
Surgical Procedures
carotid endarterectomy
Surgical procedure for removing obstruction within carotid artery, a major
artery in the neck that carries oxygenated blood to the brain; developed to
prevent strokes, but is found to be useful only in severe stenosis with
transient ischemic attack
laminectomy
Removal of a portion of a vertebra, called the lamina, in order to relieve
pressure on spinal nerve
neurectomy
Surgical removal of a nerve
neuroplasty
Surgical repair of a nerve
neurorrhaphy
To suture a nerve back together; actually refers to suturing connective tissue
sheath around the nerve
tractotomy
Precision cutting of a nerve tract in the spinal cord; used to treat intractable
pain or muscle spasms
Pharmacology
analgesic
Treats minor to moderate pain without loss of consciousness
aspirin, Bayer, Ecotrin; acetaminophen, Tylenol; ibuprofen, Motrin
anesthetic
Produces loss of sensation or loss of consciousness
lidocaine, Xylocaine; pentobarbital, Nembutal; propofol, Diprivan; procaine,
Novocain
anticonvulsant
Reduces excitability of neurons and therefore prevents uncontrolled neuron
activity associated with seizures
carbamazepine, Tegretol; phenobarbital, Nembutal
hypnotic
Promotes sleep
secobarbital, Seconal; temazepam, Restoril
narcotic analgesic
Treats severe pain; has potential to be habit forming if taken for prolonged
time; also called opiate
morphine, MS Contin; oxycodone, OxyContin; meperidine, Demerol
sedative
Has relaxing or calming effect
amobarbital, Amytal; butabarbital, Butisol
Abbreviations
AD
Alzheimer’s disease
AHT
abusive head trauma
ALS
amyotrophic lateral sclerosis
ANS
autonomic nervous system
CNS
central nervous system
CP
cerebral palsy
CSF
cerebrospinal fluid
CTE
chronic traumatic encephalopathy
CVA
cerebrovascular accident
CVD
cerebrovascular disease
EEG
electroencephalogram, electroencephalography
GA
general anesthesia
HA
headache
ICP
intracranial pressure
IV
intravenous
LP
lumbar puncture
MS
multiple sclerosis
PET
positron emission tomography
PNS
peripheral nervous system
SBS
shaken baby syndrome
SCI
spinal cord injury
TBI
traumatic brain injury
TENS
transcutaneous electrical nerve stimulation
TIA
transient ischemic attack
VS
vital signs