Digital Radiography: A New Concept in Imaging
Digital Radiography: A New Concept in Imaging
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Concept of Digital radiography
A Project
on
CONCEPT OF DIGITAL RADIOGRAPHY
BY:
KARUNA PALIWAL
(B. Sc. MEDICAL TECHNOLOGY)
(IMAGING SCIENCES)
(2007-2010)
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Concept of Digital radiography
CERTIFICATE
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Acknowledgement
Last but not the least I would like to express my gratitude towards
Symbiosis Institute of Health Sciences (SIHS) and my teachers for their support
during the course of my project.
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ABSTRACT
Medical imaging is undergoing revolutionary change at this time. Since Roentgen’s discovery of X-
rays, anatomic image have been obtained in basically same fashion. Now that is changing and
changing very rapidly.
A conventional static radiographic image is made like a shadow graph, using a field of x-rays
that forms an image pattern after transmission through the patient. The image receptor, a screen-
film combination is the device that records this transmitted image directly.
These conventional systems have served us well for many years. Providing increasingly
better diagnostic images. They both, however, have several limitations. The static radiographic
images require processing time that can delay the completion of the examination. This can be
particularly bothersome in angiography and when film-subtraction techniques are employed. Once
one has obtained such images, there is very little that can be done to enhance their information
content. When the examination is complete, the images are in the form of hard-copy film that must
be cataloged and stored for future review. Another and perhaps more severe limitation is the noise
inherent in these images.
Digital imaging techniques are being applied to computed tomography (CT) ultrasound,
radioisotope studies, and magnetic resonance imaging (MRI), digital fluoroscopy (DF), and digital
radiography (DR) and computed radiography (CR). Digital fluoroscopy and radiography are currently
under rapid development and clinical deployment. Digital imaging system uses CCDs, Phosphors
(IP), and flat panel detectors as image receptors. These advances in the field of radiography boosted
the diagnostic field, patient care and mainly the cost effectiveness.
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CONTENTS
1. Acknowledgement 4
2. Abstract 5
3. Introduction to digital radiography 7
4. Types of digital radiography 16
5. Digitizer & Digitizing an image 41
6. Implementation 46
7. Patient dose consideration 46
8. Hard copy versus Soft copy 47
9. Digital image processing 48
10. Image quality in digital radiography and advantages 53
11. Quality assurance concerns and Artifacts 57
12. Conclusion 61
13. References 62
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3.1 History
3.2 Image representation
3.2.1 Introduction
3.2.2 Spatial representation of digital image
3.3 Digital concept
3.3.1 Analog Vs Digital
3.3.2 Classification of digital radiography
[Link] Direct and Indirect digital radiography
3.4 Luminescence
3.4.1 Photoluminescence
a) Phosphoresces
b) Fluorescence
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3. Introduction
Digital radiographic image receptors are gradually replacing screen-film cassettes as radiology
departments converts to an all-digital environment. Computed tomography (CT) and magnetic
resonance imaging (MRI) are intrinsically digital, and ultrasound and nuclear medicine imaging
made the change to digital imaging from their analog ancestries in the [Link], reasons for this
are clear: screen-film is a tried and true detector system that produces excellent image quality
under most circumstances, and therefore the motivation for change is low. In addition, the large
field of view and high spatial resolution of radiography require digital radiographic image to contain
large amounts of digital data. For example, a typical CR and DR systems.
3.1 History
The development of digital radiologic imaging equipment was limited until sufficient computer
technology available to handle the large quantities of data generated. The microprocessors and
semiconductor memory made this development possible. Initial activity began in early 1970s,
developed along two independent lines, and became a clinical reality in 1980. At the 1981
International radiology meeting in Brussels, Fuji Photo Film Co., Ltd introduced the concept of
computed radiography employing photostimulable phosphor plate technology. In 1983 computed
radiography was first used clinically in Japan, and by 2003 more than 25,000 systems will be in
clinical use worldwide[2].
The medical physics groups at the University of Wisconsin and the University of Arizona
independently initiated studies of DF in the early 1970s. These studies were continued through the
decade by the research and development groups of most X-ray equipment manufacturers. The
approach in general was to use conventional fluoroscopy equipment and place a computer between
the television camera and the TV monitor. The video signal from the TV camera was shunted
through the computer, manipulated in various ways, and transmitted to the TV monitor in a form
ready for viewing.
Although there are several approaches to DR, the approach developed in the late 1970s to
complement computed tomography has enjoyed the widest application, invented by Godfrey
Hounsfield. Analog to digital converters and computers were also adapted to conventional
fluoroscopic image intensifier/TV systems in the 70's as well. Angiographic procedures for looking at
the blood vessels in the brain, kidneys, arms and legs, and the blood vessels of the heart all have
benefited tremendously from the adaptation of digital technology.
Over the next ten to fifteen years a large majority of conventional x-ray systems will also be
upgraded to all digital technology. Eventually, all of the film cassette/film screen systems will be
replaced by digital x-ray detectors. This technology is currently works-in-progress and is only
available at a handful of sites worldwide. An intermediate step called phosphor plate technology in
currently available at hundreds of sites around the world. These plates trap the x-ray energy and
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require an intermediate processing step to release the stored information so it can be converted
into a digital picture.
Image plates were pioneered for commercial use by Fuji in the 1980s. In modern hospitals a
photostimulable phosphor plate (PSP plate) is used in place of the photographic plate. After the
plate is X-rayed, excited electrons in the phosphor material remain "trapped" in "colour centers" in
the crystal lattice until stimulated by a laser beam passed over the plate surface. Since the 1970s,
new semiconductor detectors have been developed (silicon or germanium doped with lithium, Si (Li)
or Ge (Li)). X-ray photons are converted to electron-hole pairs in the semiconductor and are
collected to detect the X-rays. When the temperature is low enough (the detector is cooled by
Peltier effect or even cooler liquid nitrogen), it is possible to directly determine the X-ray energy
spectrum; this method is called energy dispersive X-ray spectroscopy. Practical application in
medical imaging started in the 1990s. Currently amorphous selenium is used in commercial large
area flat panel X-ray detectors for mammography and chest radiography.
3.2.1 Introduction
This chapter centers around the question of how to represent the information contained in images.
First, the information contained in images can be represented in entirely different ways. The most
important are the spatial representation (Section 2.2) and wave number representation (Section
2.3). These representations just look at spatial data from different points of view. Since the various
representations are complete and equivalent, they can be converted into each other. The
conversion between the spatial and wave number representation is the well-known Fourier
transform.
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represents not just a point in the image but rather a rectangular region, the elementary cell of the
grid.
The 3-D spaces (and even higher-dimensional spaces) are also of interest in image processing. In
three-dimensional images a pixel turns into a voxel, an abbreviation of volume element. On a
rectangular grid, each voxel represents the mean gray value of cuboids. The position of a voxel is
given by three indices(x, y, z axis).
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Fig. 3.2 – shows the differences between analog and digital image.
Digital radiography is the process of producing a digital image by the input of analog image with the
help of equipment known as analog to digital converter (ADC).
Digital radiography
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The classification is done on the basis of process of image formation. In, indirect radiography (e.g.
CR) the images are first formed on the image plate (i.e. latent image) which again digitized to get
the digital image. While in direct radiography there is no such material like image plate and no
latent image is formed. The images are formed digitally along with the exposure.
Digital Radiography (DR) is essentially filmless X-ray image capture. In place of X-ray film, a digital
image capture device is used to record the X-ray image and make it available as a digital file that can
be presented for interpretation and saved as part of the patient’s medical record. The advantages of
DR over film include immediate image preview and availability, a wider dynamic range which makes
it more forgiving for over- and under-exposure as well as the ability to apply special image
processing techniques that enhance overall display of the image. The largest motivator for
healthcare facilities to adopt DR is its potential to reduce costs associated with processing,
managing and storing films. Typically there are two variants of digital image capture devices. These
devices include Flat Panel detectors (FPDs), and High Density Line Scan Solid State detectors.
1. Amorphous Silicon (a-Si) is the most frequent type of FPD sold in the medical imaging industry
today. With a-Si detectors, a scintillator in the detector’s outer layer, which is made from Cesium
Iodide (CsI), or Gadolinium Oxysulfide (Gd2O2S), converts X-ray to light. Because the X-ray energy is
converted to light, the a-Si detector is considered an indirect image capture technology. The light is
then channeled through the a-Si photodiode layer where it is converted to a digital output signal.
The digital signal is then read out by Thin Film Transistors (TFT’s) or by fiber coupled Charged Couple
Devices (CCD’s). The image data file is sent to a computer for display where the X-ray technologist
can determine whether the image is appropriate for the intended anatomy. Once the Technologist
determines the image is appropriate it can be sent to the radiologist’s workstation or printed on
film for interpretation.
2. Amorphous Selenium (a-Se) FPD devices are known as “direct” detectors because no X-ray
energy conversion to light takes place within the detector. The outer layer of the flat panel in this
design is a high voltage bias electrode. The bias electrode accelerates the captured energy from an
X-ray exposure through the selenium layer. X-ray photons flowing through the selenium layer create
electron hole pairs. These electron holes transit through the selenium based on the potential of the
bias voltage charge. As the electron holes are replaced with electrons, the resultant charge pattern
in the selenium layer is read out by a TFT array or Electrometer Probes. The image data file is sent to
a computer for display where the X-ray technologist can review the image and check positioning
and if desired, transmit the image to the radiologist’s workstation for diagnosis.
3. The third type of DR detector is the High Density Line Scan Solid State device. It is comprised
of a Photostimulable Barium Fluoro Bromide doped with Europium (BaFBr:Eu) or Cesium Bromide
(CsBr) phosphor. The phosphor detector records the X-ray energy during exposure and is scanned
by a linear laser diode to excite the stored energy which is released and read out by a digital image
capture array of Charge Coupled Devices (CCD’s). The image data file is transmitted to the X-ray
technologist at a computer for review and then sent to the radiologist for further interpretation.
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3.4 Luminescence
Luminescence is the phenomenon of emission of light on absorption of energy. When an X-rays falls
on a certain material these material will emits the light. And the invisible spectrum is changed into
the visible spectrum. The emission of light from substance bombarded by radiation is termed as
luminescence.
Fluorescent materials- The material which converts the invisible radiation into luminous (visible)
radiation are known as fluorescent materials and they are commonly known as phosphors. Few of
such materials used in radiology. The phosphors are used in crystalline and pure form. The smallest
part of impurities 1/100,000 will diminish the efficiency of many phosphors. These are many
expensive.
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3.4.1 Photoluminescence
PHOTOLUMINESCENCE (abbreviated as PL) is a process in which a substance absorbs photons
(electromagnetic radiation) and then re-radiates photons (light photons). Quantum mechanically,
this can be described as an excitation to a higher energy state and then a return to a lower energy
state accompanied by the emission of a photon. This is one of many forms of luminescence (light
emission) and is distinguished by photo excitation (excitation by photons), hence the prefix photo-.
The period between absorption and emission is typically extremely short, in the order of 10
nanoseconds. Under special circumstances, however, this period can be extended into minutes or
hours.
Forms of photoluminescence
A) Fluorescence is the emission of visible light by a substance that has absorbed light of a
different wavelength. In most cases, absorption of light of a smaller wavelength induces
emission of light with a larger (less energetic) wavelength. A smaller wavelength emission is
sometimes observed from multiple photon absorption, but this occurs only under conditions
of intense radiation such as are available with laser light and stop upon the termination of
the exposure. The energy difference between the absorbed and emitted photons is
dissipated in the fluorescent material, via internal molecular vibrations and eventually heat.
The figure shown below shows the different stages involved in photoluminescence. A) Different energy states
in an atom. B) Radiation exposure results in the excitation of the electron to the higher energy state. C)
Electrons comes down to lower energy state and trapped in the F-band. D) Again during exposure to laser
light energy is absorbed by the electrons. E) Heat energy is utilized by the electrons it gets excited to
conduction band and comes down to valance band losing their energy in the form of light which is used to
get an image.
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A B C
D E
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4.1.1 Components of CR
Computed radiography (CR) is a one of the recent advancements in the field of radiology which
helps in the field diagnostic imaging. It is composed of following components:
Cassettes
Cassette houses the image plate. Image plate is one which holds the latent image onto till it is
scanned in digitizer. The cassette performs dual functions- firstly; it holds/protect the image plate.
The inner lining of cassette is made up of felt which protects against mechanical damage,
electrostatic charging, dust and dirt.
Secondly, it receives and holds the image identification data. There is a memory chip which contains
all image relevant data, patient demographics image quality related data etc.
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Imaging Plate
The CR imaging plate (IP) contains photostimulable storage phosphors, which store the radiation
level received at each point in local electron energies. When the plate is put through the scanner,
the scanning laser beam causes the electrons to relax to lower energy levels, emitting light that is
detected by a photo-multiplier tube, which is then converted to an electronic signal. The electronic
signal is then converted to discrete (digital) values and placed into the image processor pixel map.
Imaging plates can theoretically be re-used thousands of times if they are handled carefully. IP
handling under industrial conditions, however, may result in damage after a few hundred uses. An
image can be erased by simply exposing the plate to a room-level fluorescent light. Most laser
scanners automatically erase the image plate after laser scanning is complete. The imaging plate can
then be re-used. Image plate is the sensitive part on which latent image is stored. The structure of
image plate is like films in the conventional radiography. Image plate has mainly four layers – EBC
top coat, phosphor layer, adhesive layer, black PET support layer, laminate layer.
It is the protective layer of the image plate (IP). It ensures long life time of the IP and
provides efficient protection against mechanical wear during daily operation, static charging
and against cleaning solutions.
b. Phosphor layer
It is the sensitive layer of the IP which is similar to the emulsion layer of the conventional
film. IP is made of BaFBr and BaFI. Because of this mixture, the material is often just called
barium flurohalide activated with europium (BaFX:Eu3+). A CR plate is a flexible screen that is
enclosed in a cassette similar to a film-screen system. One imaging palate is used for each
exposure. The imaging is exposed in a procedure identical to screen-film radiography, and
the CR cassette is then brought to a CR reader unit. The cassette is placed in the reader unit,
and several processing steps then take place:
1. The cassette is moved into the reader and unit and the imaging plate is mechanically
removed from the cassette.
2. The imaging plate is translated across a moving stage and scanned by a laser beam.
3. The laser light stimulates the emission of trapped energy in the imaging plate, and visible
light is released from the plate.
4. The light released from the plate is collected by a fiber optic light guide and strikes a
photomultiplier tube (PMT), where it produces an electronic signal.
5. The electronic signal is digitized and stored.
6. The plate is then exposed to bright white light to erase any residual trapped energy.
7. The imaging plate is then returned to the cassette and is ready for reuse.
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c. Adhesive layer
It is the 3rd layer of the IP on which phosphor layer is mounted and the posterior connects to
the support layer (black PET layer)
It is the support layer which provides the base for mounting other layers of IP and ensures
rigidity of the imaging plate.
e. Laminate layer
It is also known as backing layer. It is a soft polymer layer to protect the plate during stacking
of a number of imaging plates.
2. Identification station: It is the part of the console where the primary data of the patient is
fed in the computer. Examples, patient’s name, age, sex, patient ID, examination/part of the
body going to be x-rayed etc. These data are useful to differentiate the patient.
3. Digitizers: Digitizers (e.g.: Aka CR Reader), are responsible for converting the Analog to a
Digital Image by the process of digitization which is explained separately.
4. Processing station: It is also the part of the console. Processing station provides the user
interface and makes these images available for user for further processing, like Rotating
image, zooming, contrast width and level, grey scale inversion, image orientation,
magnification, measurement etc.
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Advantages of IP –
1. Image plates can be reused of thousands of times for exposure to get an image.
2. Imaging plate has high exposure latitude, means any exposure can give the image.
3. A valuable characteristic of the IP is its extreme dynamic range.
Disadvantage of IP-
1. IP is costly.
2. Improper handling can give rise to artifacts.
3. The latent image is lost if it is nor processed in time i.e. Approx. 48 hours after exposure.
Products:-
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4.1.2 Working of CR -
The digital image that is generated by the CR reader is stored temporarily on a local hard disk. Many
CR systems are joined directly to laser printers that make film hard copies of the digital images. CR
system often serve as entry points into a PACS and in such cases the digital radiographs is sent to
the PACS system for interpretation by the radiologists and long term archiving. The common
sequence is as follows:
Photo stimulated luminescence (PSL) is the release of stored energy within a phosphor by
stimulation with visible light, to produce a luminescent signal. Commonly this is used to allow the
storage of a weak radioactive signal in a phosphor plate that takes the place of X-ray film,
potentially over a prolonged period, which PSL transforms to obtain a highly sensitive image of the
original pattern of radiation. Also known as an image plate, a photostimulable phosphor (PSP)
plate can be used record a two-dimensional image of the intensity short-wavelength (typically, X-
ray) electromagnetic radiation. The device to read such a plate is known as a phosphor imager
(occasionally abbreviated to phosphor imager, perhaps reflecting its common application in
molecular biology of detecting radiolabled phosphorylated proteins and nucleic acids).
Creating an image requires illuminating the plate twice: the first exposure, to the radiation of
interest, "writes" the image, and a later, second illumination (typically by a visible-wavelength laser)
"reads" the image.
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Fig : it show the different stages involved in the acquisition of the computed radiograph.
The imaging plate is a completely analog device, but it is read out by analog and digital electronic
techniques as shown in Fig. The imaging plate is translated along the readout stage in the vertical
direction and a scanning laser beam interrogates the plate horizontally. The laser is scanned with
the use of rotating multifaceted mirror. As the red laser light from helium-neon laser strikes the
imaging phosphor at a location, the trapped energy from the x-ray exposure at the location is
released from the imaging plate. A fraction of the emitted light travels through the fiber optic light
guide and reaches the PMT. The electronic signal that is produced by the PMT is digitized and stored
in the memory. Therefore for every spatial location (x, y), a corresponding gray scale value is
determined, and this is how the digital image is produced in a CR reader.
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The light that is released from the imaging plate is of a different color than the stimulating laser
light (fig). To eliminate detection by the PMT of the scattered laser light, an optical filter that
transmits the blue-green light that is emitted from the imaging plate, but attenuates the red laser
light, is mounted in the front of PMT.
Fig describes how stimulated phosphor work. A small mass of screen material is shown being
exposed to the X-rays. Typically imaging plates are composed of about 85% BaFBr and 15% BaFI,
activated with small amount of europium. The activation procedure, also called doping, creates
defects in the BaFBr crystals that allow electrons to get trapped more efficiently.
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When the X-ray energy is absorbed by the BaFBr phosphor, the absorbed energy excites
electrons associated with the europium atom, causing divalent europium atoms (Eu2+) to be
oxidized and changed to the trivalent state (Eu3+). The excited electrons become mobile, and some
fraction of them interacts with a so called F-center. The F-center traps these electrons in a higher
energy, metastable state where they can remain for days to weeks, with some fading over time. The
latent image that exists on the imaging plate after X-ray exposure, but before reading out, exists as
billions of electrons trapped in F-centers. The number of trapped electrons per unit area of the
imaging plate is proportional to the intensity of X-rays incident at each location during exposure.
When the red laser light scans the exposed imaging plate, the red light is absorbed at F-center
where the energy of the red light is transferred to the electron. The photon energy of the red laser
light is less than that of the blue-green emission (ΔEred < ΔEblue green). However, the electron gains
enough energy to reach to the conduction band, enabling it to become mobile again. Many of these
electrons then become de-excited by releasing blue-green light as they become reabsorbed by the
trivalent europium atoms, converting them back to the divalent state. This is how the red laser light
stimulates emission of the blue and green light photons from the imaging plate.
The first readout of the imaging plate does not release all of the trapped electrons that form the
latent image; indeed a plate can be read a second time and a third time with only slight
degradation. To erase the latent image so that the imaging plate can be reused for another
exposure without ghosting, the plate is exposed to very bright light source, which flushes almost all
of the metastable electrons to their ground state, emptying most of the F-centers.
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CR systems operate with a workflow pattern very similar to the screen-film radiography, CR
cassettes is exposed just like screen-film cassette, and they then brought to a reader unit, just as a
film-screen cassettes are brought to the film processors. The similarity in handling of the CR and
screen-film cassettes contributed to the initial success of CR. One of the disadvantages that CR over
screen-film radiography is its much larger dynamic range; in other words, the exposure latitude with
CR is much wider than with screen-film radiography system. Consequently, retakes due to
overexposure or underexposure are rare with CR. Although CR is capable of producing images with
proper grey scale at low and high exposure levels, quality assurance efforts should still be in place to
ensure proper exposure levels. CR images exposed to low exposure levels, while maintaining proper
grey scale in the image, have higher level of x-ray quantum noise. CR images produced at high
exposure have low quantum noise but result in higher x-ray dose to the patients
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4.1.3 Applications
CR and DR should not be confused with fluoroscopy, where there is a continuous beam of radiation,
and the images appear on the screen like on a TV. This is the system many people are familiar with,
where the image of the article being x-rayed is viewed in real time on a monitor or display. Many
people think airports use Fluoroscopes for baggage inspection, when in fact LDA's (Linear Diode
Arrays) are universally used to generate static images of luggage content. LDA's are also used in a
wide variety of other screening and imaging applications, and are also presented in a digital format.
Modern fluoroscopes use a device called an image intensifier to enhance the analog output of the
real time x-ray image, where it is picked up by either a video or CCD camera and digitally enhanced
to reduce the noise inherent in the system.
Industrial applications
Medical applications
Computed Radiography systems are the most common in medical applications because they have
proven reliability over more than two decades, flexibility to address a variety of clinical applications
and lower costs to take multiple exam rooms digital. DR systems are generally sold as full x-ray
room replacements and tied to a single x-ray generator. CR IPs can be retrofitted to existing exam
rooms and used in multiple x-ray sites since IPs are processed through a CR reader (scanner) that
can be shared between multiple exam rooms.
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Advantages
Disadvantages
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CCDs form images from visible light. CCD detectors are used in most modern vediocameras and in
digital cameras. The principal feature of the CCD detectors is that the CCD chip is itself is an
integrated circuit made of crystalline silicon, similar to the central processing unit of the computers.
A CCD chip has discrete pixel electronic etched into its surface; for example, a 2.5 x 2.5 cm CCD chip
may have 1024 x 1024 or 2048 x 2048 pixels on its surface. Large chip spanning 8 x 8 cm have been
produced. The silicon surface of the CCD is photosensitive – as visible light falls on each pixel,
electrons are liberated and build up in the pixel. More electrons are produced in a pixel that
receives greater light intensity. The electrons are kept in each pixel because there are electronic
barriers (voltage) on each side of pixel during exposure.
Once CCD chip has been exposed, the electronic charge that resides in each pixel is readout.
The readout process is akin to a bucket brigade (Fig.). Along one column of the CCD chip, the
electronic charge is shifted pixel by pixel by appropriate control of voltage levels at the boundaries
of each pixel. The charge from each pixel in the entire column is shifted simultaneously, in parallel.
For linear CCD detector, the entire line of pixels is thus read out one by one, in a shift and read, shift
and read process. For a two dimensional CCD detectors, the change on each column are shifted
onto the bottom row of pixels, that entire row is read out horizontally, and then the next charges
from all columns are shifted down one pixel, and so on.
CCD cameras produce high-quality images from visible light exposure and are commonly
used in medical imaging for fluoroscopy and digital cineradiography. In these devices, the amplified
light generated by the image intensifier is focused with the lenses or fiber optics on to the CCD chip
(Fig.). For a small field of view applications such as dental radiography (e.g., 25 x 50 detectors), an
intensifying screen is placed in front of the CCD chip and the system is exposed. The light emitted
from the screen is collected by the CCD chip, and because of the excellent coupling between the
screen and the CCD chip only a relatively small amount of the light generated in the screen is
wasted ( i.e., does not reaches to the CCD). For application in which the field of view is only slightly
larger than the area of CCD chip, such as digital biopsy system in mammography, a fiber optic taper
is placed in between the fiber optic and CCD (Fig.). The fiber optic taper serves as an efficient lens
that focuses the light produced in the screen onto the surface of CCD chip. Typically fiber optic taper
used in digital biopsy system have front surface that measures 50 x 50 mm (abutted to the screen)
and output surface that are 25 x 25 mm (abutted to the CCD). In these systems, the amount of light
lost in fiber optic taper is not trivial, but a substantial fraction of the light reaches the CCD chip.
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When there is a need to image a large field of view, such as in chest radiography, it is impossible to
focus the light emitted from the large screen (approximately 35 x 43 cm) onto the surface of CCD
chip without losing a large fraction of the light photons. The amount of light lost is proportional to
the demagnification factor required to couple the input area to the output area. As an example, the
area ratio (demagnification factor) for 35 x 43 cm chest radiography using a 30 x 30 mm CCD chip is
167:1. Even with perfect lenses in such system, the light loss is approximately 99.7%. Because an
insufficient number of quanta are used to conduct an image through an imaging chain after the
initial x-ray detection stage, a secondary quantum sink will occur. Although an image can be
produced if a sufficient number of x-ray photons are used, any x-ray system with a secondary
quantum sink will have image quality that is not commensurate with the x-ray dose used to make
the image.
Fig:- CCD are pixilated light detectors in which electronic charge builds up in each detectors
elements as a response to light exposure. After exposure, by toggling voltages between
adjacent detector elements, the charge packets are made to move in simultaneously down
each column of the array. After the charge packets have been shifted down one detector
element in each column, the bottom row of pixels is refreshed. This bottom row is readout
horizontally, in a bucket brigade fashion, so that the charged packet from each detector
element reaches the readout electronics of the CCD.
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Fig:- A: the top frame show the CCD chip coupled through tandem lenses to the output of an
image intensifier. Because of the huge light amplification of the image intensifier, many
thousands of light photons are produced by the absorption of an X-Ray photon. A small
fraction of these light photon pass through the lenses and are focused on to the CCD chip.
Although many light photons are lost in the lens and the aperture, the huge gain of the image
intensifiers ensures that a secondary quantum sink is avoided. B: digital mammography biopsy
system makes use of fiber optic coupling between a small field of view intensifying screen and
a CCD chip. Because the demagnification factor is low and the fiber optic lens is efficient, a
secondary quantum sink is avoided. C: for large field of view(FOV) applications, the use of
lenses coupled to an intensifying screen results an substantial loss of the light photons emitted
by X-ray interaction in the screen. This type of system suffers from a secondary quantum sink.
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Fig; The figure shows the two types of Flat panel detectors image acquisition mechanism.
The first one show the Indirect flat panel and second, is the direct flat panel detector system.
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general radiography use CsI screens instead of Gd2O2S. CsI is grown in columnar crystals and the
columns act as light pipes to reduce the lateral spread of light.
A typical configuration for a flat panel detector system is shown in (Fig. 4-7). The flat panel
comprises a large number of individual detector elements, each one capable of storing charge in
response to x-ray exposure. Each detector element has a light sensitive region, and a small corner of
it contains the electronics. Just before exposure, the capacitor, which stores the accumulated x-ray
signal on each detector element, is shunted to ground, dissipating lingering charge and resetting the
device. The light sensitive region is a photoconductor, and electrons are released in the
photoconductor region on exposure to visible light. During exposure, charge is built up in each
detector element and is held thereby the capacitor. After exposure, the charge in each detector
element is readout using electronics as illustrated in (Fig. 4-8).
A transistor is a simple electronic switch that has three electrical connections- the gate, the source,
and the drain. Each detector element in a flat panel detector has a transistor associated with it; the
source is the capacitor that stores the charge accumulated during exposure, the drain is connected
to the readout line (vertical wires in fig. 4-8.), and the gate is connected to the horizontal wires
shown in (Fig. 4-8). Negative voltage applied to the gate causes the switch to be turned off (no
conduction from source to drain), whereas when a positive voltage is applied to the gate the switch
is turned on (source is connected to drain). Because each detector element has a transistor and the
device is manufactured using thin film deposition technology, these flat panel systems are called
thin-film transistor (TFT) image receptors.
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The readout procedure occurs as follows. During exposure, negative voltage is applied to all gate
lines, causing all of the transistor switches on the flat panel imager to be turned off. Therefore,
charge accumulated during exposure remains at the capacitor in each detector element. During
readout, positive voltage is sequentially applied to each gate line (e.g., R1, R2, R3, as shown in fig.
4-8), one gate line at a time. Thus, the switches for all detector elements along a row are turned on.
The multiplexer (top of fig. 4-8) is a device with a series of switches in which one switch is opened at
a time. The multiplexer sequentially connects each vertical wire (e.g. C1, C2, C3), via switches (S1,
S2, S3), to the digitizer, allowing each detector element along each row to be read out. For example,
referring to fig.4-8, when wire R2 is set to a positive gate voltage (all other horizontal wires being
negative), the switches on detector elements D, E, and F are opened. Therefore, current can in
principle flow between each of these detector elements (source) and the digitizer (drain). In the
multiplexer, if the switches S1 and S3 are turned off and S2 is on, then the electrons accumulated on
the detector element E are free to flow(under the influence of an applied voltage) from the storage
capacitor, through the charge amplifier, through the multiplexer (S2 is open) to the digitizer. Thus,
the array of detector elements is readout in a raster fashion, with the gate line selecting the row
and the multiplexer selecting the column. By this sequential readout approach, the charge from
each detector element is readout from the flat panel, digitized, and stored, forming a digital image.
Notice that in this procedure the signal from each detector element does not pass through any
other detector elements, as it does in a CCD camera. This means that the charge transfer efficiency
in a flat panel imager needs only to be good (approximately 98%), whereas for a CCD the charge
transfer efficiency needs to be excellent (greater than 99.9%). Therefore, flat panel systems are less
susceptible to imperfections that occur during fabrication.
The size of the detector element on a flat panel largely determines the spatial resolution of
the detector system. For example, for a flat panel with 125 x 125 µm pixels, the maximum spatial
frequency that can be conveyed in the image (the Nyquist frequency, FN) is (2 x 0.125 mm)-1 , or 4
cycles/mm. because it is desirable to have a high spatial resolution, small detector elements are
needed. However, the electronics (e.g.; the switch, capacitor, etc) of each detector element takes
up a certain amount of the area, so, for flat panel with smaller detector elements, a larger fraction
of the detector elements area is not sensitive to light. Therefore, the light collection efficiency
decreases as the detector elements get smaller. The ratio of the light sensitive area to the entire
area of each detector element is called the fill factor.
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It is desirable to have a high fill factor, because light photons that are not detected do not
contribute to the image. If a sufficient number of the light photons generated in the intensifying
screen are lost owing to a low fill factor, then contrast resolution (which is related to the signal to
noise ratio) will be degraded. Therefore, the choice of the detector element dimensions required a
tradeoff between spatial resolution and contrast resolution.
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With indirect systems, the light that is released in the intensifying screen diffuses as it
propagates to the TFT array, and this causes a certain amount of blurring. This blurring is identical to
that experienced in the screen film detectors. For indirect flat panel detectors, the columnar
structure of CsI is often exploited to reduce lateral spread but a significant amount of lateral
blurring does still occur. For direct detection system, in contrast, electrons are the secondary quanta
that carry the signal. Electrons are made to travel with a high degree of directionality by the
application of electric field. Therefore, virtually no blurring occurs in direct flat panel detectors.
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Selenium (Z=34) has a higher atomic number than silicon (Z=14), but it is still quite low
compared with conventional X-ray intensifying screen phosphors that contain element such as
gadolinium (Z=64) or cesium (Z=55), and therefore the attenuation coefficient is relatively low at
diagnostic X-ray energies (40 to 130 keV). Intensifying screens need to be kept thin enough to
reduce light spreading thereby preserve spatial resolution. However, because electrons do not
spread laterally in the selenium direct detectors due to the electric field, selenium detectors made
much thicker than indirect detection system, to improve X-ray detection efficiency. Making the
selenium detectors thicker compensates for the relatively low X-ray absorption of selenium. In
addition to selenium, other materials such as mercuric oxide (HgI2), cadmium telluride (CdTe), and
lead iodide (PbI2) are being studied for the use in direct detection flat panel.
Fig. : CsI phosphor detection system has better dose efficiency, whereas a-Se can provide better
spatial resolution.
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4.3 CR versus DR
Computed radiography (CR) is often distinguished from Digital Radiography (DR). CR and DR have
many similarities. Both CR and DR use a medium to capture x-ray energy and both produce a digital
image that can be enhanced for soft copy diagnosis or further review. CR generally involves the use
of a cassette that houses the imaging plate, similar to traditional film-screen systems, to record the
image whereas DR typically captures the image directly onto a flat panel detector without the use of
a cassette. Image processing or enhancement can be applied on DR images as well as CR images due
to the digital format of each. There are many different types of DR detectors.
Procedure Like film radiography, CR requires DR requires exposing the digital panel.
exposing the cassette. The cassette is then Image is then immediately available for
moved from the inspection site to the evaluation of the PC without moving the
reader location. The CR plate is digitally panel from the inspection site.
imaged, and the is evaluated on the PC.
Portability CR cassette is very portable. The CR The DR panel can be field portable,
reader/eraser is not portable and requires depending on the panel size.
an electrical power source.
Resolution The highest currently available resolution, The highest available resolution is the
with CR is 100 microns, with new 50 Envision 4x4 at 48 microns. The time to
micron versions available soon. At 100 acquire the image is typically 12 seconds.
microns, from 1 to 5 minutes is required
to digitize the image and ½ to 2 minutes to
erase depending on brand.
Speed Like film, CR requires multiple steps. DR is much faster than CR. It can provide
Typically CR takes 2-10 minutes or more image within a few seconds, mainly from 5
for taking the cassette to the reader, to 20 seconds.
reading, erasing, and returning to the
inspection site.
Production use Like film, the multi-step process for usingDR can provide continuous inspection of
CR is too slow for most production hundreds or even thousands of part per
applications. hour. Automatic detect recognition (ADR) is
also an option.
Cost CR systems require the purchase of a DR systems require the purchase of an
reader/eraser workstation with PC, display imaging panel, cable, PC, display and
and software also cassette. But it cost software.
effective than DR system.
Strengths CR excels for field operations where DR excels for production applications
access is limited or imaging plate must where speed and/or image quality are
conform to the object shape. paramount. Also, DR linear arrays can
provide X-ray views without parallax.
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5.1 Digitizer
5.2 Components
5.3 Process of digitization
5.4 Advantages of digitization
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Concept of Digital radiography
4.1 Digitizer
Digitizer is responsible for converting the analog image into digital image. In simple words it is
responsible for converting the latent image into digital image which are used by the
computers for further used for image processing.
• Input/output slot
• Cassette unit
• IP transport units
• Scan unit
• Eraser unit
• CPU assembly
• Power unit
- It has an input/output slot where the cassette is inserted for scanning or ejected by the
Digitizer after the scanning and erasing is done.
- It has cassette units, which perform the operation of opening and closing the cassettes to
facilitate access to image plate for the rest of assembly.
- It has an image plate transport unit, which do the function of transporting the image plate
to and from the cassette unit to and from the scan unit. They rely upon a suction cup
assembly for pickup of the image plate.
- It has a scan unit, which is heart of the digitizer. It performs the operation of converting
latent X-ray image into 12 bit raw digital image.
- It has an erasure unit, which removes all the residual image data, which is not required after
the scanning of the image plate is done. It is nothing; but a high intensity halogen lamp does
the function of erasing.
- It has a CPU assembly, which controls and co-ordinates the overall function of the digitizer.
It is also responsible for the networking of the same in a LAN.
- It has a power unit, to provide each and every electrical/ electronic component of the entire
system, the required power at required voltage.
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Process in DIGITIZER-
Laser light stimulates the emission of trapped energy in the form of visible light
Collected by fiber optic light guide and allows to strikes the PMT to produce electronic signal
1. Scanning
2. Sampling
3. Quantization
1. Scanning: - The first step in digitization is division of the picture into small regions, a process
known as scanning. Each small region of the picture is called a picture element, or pixel. It
results in formation of grid consists of rows and columns. The size of the grid usually
depends on the number of pixels on each side of grid. The rows and columns play a role in
identifying a particular pixel by providing an address for that pixel. The rows and columns
make up what has been referred to as a matrix.
2. Sampling: - The second step in digitizing an image is sampling, a procedure done on the
entire image in which the brightness of each pixel is measured. A small spot of light is
projected on to the transparency and a photomultiplier tube positioned behind the picture
detects the transmitted light. The output of the photomultiplier tube is an electrical signal
(analog signal).
3. Quantization: - Quantization is the final step in digitizing a picture. In quantization, the
brightness value of each pixel sampled is assigned an integer (0, or a positive or negative
number) called a gray level. This is done for all the pixels that make up the picture and the
result is a range of numbers or gray levels, each of which has a precise location on the
rectangular grid of pixels. The total number gray level is called the gray scale. In
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Concept of Digital radiography
quantization, the electrical signal is assigned an integer based on strength of the signal. In
general, the value of the integer is proportional to the signal strength. At the end of the
quantization process we have a digital image, an array of numbers representing the analog
image that we scanned, sampled and quantized. This array of numbers is sent to the
computer for further processing.
The major goal of digitization is that a computer can process digital images. Some of the
major advantages of digitization are:-
1. Image Enhancement: - The image can be made to look more pleasing to the observer.
Certain characteristics of the image, such as contours and shapes, can be enhanced to
improve the overall quality of the image.
2. Image Restoration: - Poor images can be filtered to remove unwanted Noise a technique
referred to as filtering. Filtering can also help to remove unnecessary fine detail in the
image, a technique known as smoothing.
3. Image Analysis: - This is also referred to as scene analysis, which seeks to extract the
information contained in various objects in a scene without placing any interpretation on
them.
4. Image Detection: - The advantage of detection is to allow the observer to look for
specific shapes, contours, or textures while disregarding the other features in the image.
5. Pattern Recognition: - In digital image processing, the computer can see structures and
identify patterns.
6. Geometric Transformation: - In this process, images can be rotated or scaled by
changing the position of the pixels.
7. Data Compression: - The compression of digital images reduces the amount of data that
make up the image. This is important when the data has to be stored or transmitted.
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6. IMPLEMENTATION
The choice of the digital detector system requires a careful assessment of the needs of the facility.
CR is often the first digital radiographic system that is installed in a hospital, because it can be used
for providing portable examinations, where the cost of retakes in both time and money is high. A
significant benefit of CR over TFT based digital radiographic technology is that the reader is
stationary, but because the CR plates themselves are relatively inexpensive, several dozen plates
may be used in different radiographic rooms simultaneously. The number of rooms that one CR
reader can serve depends on the types of rooms, workload, and proximity. Typically, one CR reader
can handle the workload of three radiographic rooms. The cost of an individual flat panel detector is
high, and it can only be in one place at one time. The obvious utility for flat panel detectors is for
radiographic suites that have high patient throughput, such as a dedicated chest room. Because no
cassette handling is required and the images are rapidly available for checking positioning, the
through put in a single room using flat panel detectors can be much higher than for screen-film or
CR systems.
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Concept of Digital radiography
Flat panel detectors can reduce radiation dose by about twofold to threefold for adult imaging,
compared with CR for the same image quality, owing to the better quantum absorption and
conversion efficiency associated with that technology.
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In the absence of X-rays, each detector element has a certain amount of electronic noise
associated with it (“dark noise”). Finite gray scale values result from image acquisition in the
absence of X-rays, depending on the dark noise in each individual detector element. These noise
values are different from exposure to exposure, but a large number of dark images can be acquired
and averaged together, generating an average dark image D(x, y). This dark image is subtracted
from the images produced by the detector array.
Even for properly functioning detectors, there are subtle differences in the sensitivity of each
detector element. For large detector arrays, several amplifiers are used, and each one has a slightly
different gain. In some digital detector array systems, the amplifiers are associated with different
regions (i.e., adjacent groups of columns) of the detector: without correction, an obvious banding
pattern would be visible on the image. To correct the differences in gain between the detector
elements in the array, a gain image or flat field image is acquired. Figure 11-13 shows an image,
with and without flat field correction. To acquire a flat field image, the array is exposed to a
homogenous signal(a uniform X-ray beam with perhaps a copper filter placed near the X-ray tube to
approximate patient attenuation), and a series of images are acquired and averaged. This produces
the initial gain image G’(x, y). The dark image, D(x, y), is subtracted from the initial gain image to
obtain the gain image: G(x, y) = G’(x, y) - D(x, y). The average gray scale value on the gain image is
computed, and this may be designated Ĝ.
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Fig 9.1 : a) image before digital correction b) image after digital image correction.
When an initial (raw) medical X-ray image, Intw(x, y), is acquired, it is corrected to yield the final
image I(x, y) with the following equation:
Virtually all digital X-ray detector systems with discrete detector elements make use of digital image
correction techniques. CR systems do not have discrete detectors, and so these techniques are not
applied in CR. However, corrections are applied to each row in a CR image to compensate for
differences in light conduction efficiency of the light guide. This correction process is conceptually
identical to the flat field correction described earlier for discrete detector array systems; however,
they are applied in only one dimension.
2. GLOBAL PROCESSING
One of the most common methods of image processing in radiology is performed by altering the
relation between digital numbers in the image and displayed brightness. Windowing and leveling of
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Concept of Digital radiography
a digital image are common examples of this type of global image processing. Windowing and
leveling are simple procedures formed routinely; however, the consequences on the displayed
image are profound (fig11-14).14). Reversing the contrast of an image (changing an image with white
bones to one with black bones) is also a global processing technique. Global processing is often
performed by the display hardware instead of through manipulation of the image data directly.
Mathematically, global processing (including windowing and leveling) is performed by multiplying
and adding the gray scale value of each pixel in the image by (the same) constants and then
applying thresholding techniques. For example, image I(x I(x, y)) can be windowed and leveled to
produce image I ’(x, y),
), as following:
I ’(x, y) = b x [I(x, y) - a]
Then, limits are placed on image I’(x,y) to constrain the possible gray scale values to within the
dynamic range of the display system (usually 256 gray scale units
units- 8 bits). This is done
d by defining
upper (Thigh) and lower (Tlow) threshold limits:
Notice that the image is inverted in contrast when the constant b is negative.
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Where I(x) is the input, g(x) is the result, b(x) is called the convolution kernel. When applied to
digital images, this integral equation results in essentially just shifting and adding gray scale values.
The functional form of the convolution kernel b(x) (i.e., its shape when plotted) can have a profound
influence on the appearance of the processed image. Let us take the example of simple 3x3
convolution kernel, and examine how the nine values that result can be manipulated to achieve
different effects. The following kernel is called a delta function, and convolving with it does not
change an image in anyway:
0 0 0
0 1 0
0 0 0
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Concept of Digital radiography
An entire image can be shifted one pixel to the left by the following kernel:
0 0 0
1 0 0
0 0 0
When all the values in the kernel are positive and non-zero, the kernel blur an image. For example,
the following kernel smoothes some of the noise in an image but also reduces its resolution
somewhat:
1 1 1
1 1 1
1 1 1
Smoothing with a 3 x 3 kernel produces a subtle blurring effect. However the convolution can be
performed using a larger kernel (for e.g., 11 x 11) to achieve substantial blurring effects that are
easy to see (fig.)
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Cinical application
The process begins at the reception desk, where demographic information (patient name, birth date,
sex, identification [ID] number, examination ordered) is entered in the reception terminal transfer of
this information to the computed radiography processor may be accomplished directly via a radiology
information system (RIS) or health information system (HIS) interface, bar code, magnetic card, or
optical scanner. The
radiographer exposes the IP in the same manner as a convention film-screen system. The exposure
may be made using tabletop, mobile, or table/wall Bucky technique. The exposed imaging plate
cassette is taken to the control terminal of the CR reader unit. There, the patient demographic and
examination information is entered, and the cassette is scanned with the e bar code reader. In this
way, each specific exposed IP is linked to the correct patient and image data. This step replaces the
typical ID cameras stem in the film radiography.
The radiographer inserts the exposed cassette into the computed radiography reader. Once inside,
the cassette is automatically opened, the image plate is scanned, erased and returned to the cassette
or an internal stacker for use on another patient.
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Energy substraction is a recently developed type of processing. It requires the use of two image
plate with a 1mm copper filter sandwiched between them. The first plate records the full energy
spectrum of the radiation beam. Radiation that passes through the first plate undergoes low energy
filtration (bean hardening) by the copper filter before it enters the second plate. The image recorded
by the second plate consists primarily of the high energy component of the beam: therefore the
bone/calcium contrast is markedly reduced over that in the image recorded on the first plate. The
substraction process, aided by the computer, takes place twice. This provides one image of the soft
tissue and a second image of the bone and calcium.
Pitfalls
Correctly produced computed radiography images have few undesirable characteristics, and these
will not cause diagnostic problems, even with a relatively inexperienced operator. Edge-
enhancements artifacts are the primary problems in this type of imaging. In certain circumstances,
edge enhancement creates an appearance that may be confused with the pathologic disorder. On the
edge enhanced image a dark band may appear at the interface between the structures that differ
widely in density. This effect is primarily seen in CR images involving metal prosthesis and barium
contrast study. The dark line of the edge enhancement artifact is always perfectly symmetric around
the dense object, which makes it relatively easy to distinguish from a lesion causing lucency.
Benefits
When CR/DR system is used, several benefits are readily apparent. These benefits are discussed in the
following sections:
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Concept of Digital radiography
Teleradiographic transmission
Image plate reader devices can be linked via dedicated phone lines, microwave transmission, or
other teleradiographic means to centralize the review of the image. This sharing is an obvious benefit
to affiliated hospitals or clinics that are separated by large geographic distance but shares
professional staffs.
Advantages of PACS:-
1 Near complete elimination of last films.
2 Quicker access to prior examinations.
3 Ability to compare multi modality images on same patient.
4 4 Availability of full digital data when interpreting exams.
5 Ability for a single exam to be viewed in multiple locations at the same time.
6 Potential improvements in workflow.
Disadvantages of PACS:-
1 High initial cost.
2Lower reliability than film based systems.
3 Learning a new paradigm for radiologist interpretations of examinations.
4 Potential decreases in diagnostic ability.
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Artifacts
Computed radiography system based on photostimulable phosphor technology is now being more
widely used in radiology departments in our country. This warrants radiologists to be familiar with
its technical principles and image quality and therefore artifacts that degrade image quality.
Although most artifacts that occur in conventional radiography have become familiar, computed
radiography (CR) systems produce artifacts that differ from those found in conventional
radiography.
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Concept of Digital radiography
- Backscatter – shows the general foggy appearance on the image (fig11.1b). The solution is to
apply lead foils to the back of the cassette.
Fig 11.1 : A) image artifact due to crack IP; B) image artifact due to backscatter
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Concept of Digital radiography
Absence of malfunctioning
bucky, loading IP into with grid
lines parallel to the reader scan
lines.
-
3. Printer Artifacts
- Fine white lines from debris on mirror in printer (fig 11.3). This is due to inadequate erasure,
increase exposure cycle times.
4. Operator ARTIFACTS
- Insufficient collimation = incorrect exposure range (S) reading
- Backward cassette- when the cassette is loaded upside down (fig11.4). To avoid this load the
cassette properly
- Underexposure = quantum mottle
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DR Processing Artifacts
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12. Conclusion
The CR/DR systems completely eliminated all dark room process and ultimately increase
department efficiency. Computed radiography will improve both the operational and diagnostic
efficiency of radiography departments. With the placement of conventional projection
radiography in digital format, computed radiography forms the keystone for PACS. CR improves
the efficiency of conventional projection radiography by providing consistent image quality,
decreasing repeat exposure, and minimizing patient radiation exposure, and decreasing lost
images. By realizing such benefits, many departments have already found that CR/DR is
justifiable long term investment.
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Reference –
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