Name : Mr. SHRI BHAGUTI SINGH Patient UID.

: 10602745
Age/Gender : 74 Yrs/Male Visit No. : 0849225120400001
Referred Client : LDPLUP309-CPL Collected on : 04-Dec-2025 05:24AM
Referred By : WELL CARE DIAGNOSTIC Received on : 04-Dec-2025 05:24AM
Doctor Name : Dr. S G P G I Reported on : 04-Dec-2025 05:26AM
Sample Type : Whole Blood EDTA - 19742469

HAEMATOLOGY
Test Name Results Unit Bio. Ref. Interval
HBA1C -GLYCOSYLATED HEMOGLOBIN
Hb A1C, GLYCOSYLATED Hb,wb edta 8.10 % Normal <5.7%
Methodology: by HPLC Prediabetes 5.7% to 6.4%
Diabetes 6.5% or higher
Estimated Average Glucose 185.77 mg/dL 68-125
INTERPRETATION

AS PER AMERICAN DIABETES ASSOCIATION (ADA)

Non diabetic adults >=18 years < 5.7

At risk (Prediabetes) 5.7 - 6.4

Diagnosing Diabetes >= 6.5

CLINICAL NOTES
In vitro quantitative determination of HbA1c in whole blood is utilized in long term monitoring of [Link] HbA1c level correlates with the mean glucose concentration
prevailing in the course of the patient's recent history (approx - 6-8 weeks) and therefore provides much more reliable information for glycemia monitoring than do determinations
of blood glucose or urinary glucose. It is recommended that the determination of HbA1c be performed at intervals of 4-6 weeks during Diabetes Mellitus therapy. Results of HbA1c
should be assessed in conjunction with the patient's medical history, clinical examinations and other findings.

Some of the factors that influence HbA1c and its measurement [Adapted from Gallagher et al ]
1. Erythropoiesis
- Increased HbA1c: iron, vitamin B12 deficiency, decreased erythropoiesis.
- Decreased HbA1c: administration of erythropoietin, iron, vitamin B12, reticulocytosis, chronic liver disease.
2. Altered Haemoglobin-Genetic or chemical alterations in hemoglobin: hemoglobinopathies, HbF, methemoglobin, may increase or decrease HbA1c.
3. Glycation
- Increased HbA1c: alcoholism, chronic renal failure, decreased intraerythrocytic pH.
- Decreased HbA1c: certain hemoglobinopathies, increased intra-erythrocyte pH.
4. Erythrocyte destruction
- Increased HbA1c: increased erythrocyte life span: Splenectomy.
- Decreased A1c: decreased RBC life span: hemoglobinopathies, splenomegaly, rheumatoid arthritis or drugs such as antiretrovirals, ribavirin & dapsone.
5. Others
- Increased HbA1c: hyperbilirubinemia, carbamylated hemoglobin, alcoholism, large doses of aspirin, chronic opiate use,chronic renal failure
- Decreased HbA1c: hypertriglyceridemia,reticulocytosis, chronic liver disease, aspirin, vitamin C and E,splenomegaly, rheumatoid arthritis or drugs

Note:
[Link] RBC life span –HbA1c test will not be accurate when a person has a condition that affects the average lifespan of red blood cells (RBCs), such as hemolytic anemia
or blood loss. When the lifespan of RBCs in circulation is shortened, the A1c result is falsely low and is an unreliable measurement of a person's average glucose over time.
[Link] forms of hemoglobin – The presence of some hemoglobin variants, such as hemoglobin S in sickle cell anemia, may affect certain methods for measuring A1c. In
these cases, fructosamine can be used to monitor glucose control.

estimated Average Glucose (eAG) : based on value calculated according to National Glycohemoglobin Standardization Program (NGSP) criteria.

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