Stat H-101 (Introduction to Statistics)
Problem-1
The data below show the gestational age in weeks of the 50 fetuses underwent the fetal surgery for
myelomeningocele closure (MMC).
25, 25, 26, 27, 29, 29, 29, 30, 30, 31, 32, 32, 32, 33, 33, 33, 33, 34, 34, 34, 35, 35, 35, 35, 35, 35,
35, 35, 35, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 36, 37, 37
(a) Construct a stem-and-leaf plot for these gestational ages.
(b) Based on the stem-and-leaf plot, what one word would you use to describe the nature of the
data?
(c) Why do you think the stem-and-leaf plot looks the way it does?
(d) Compute the (i) mean, median, lower quartile and upper quartile (ii) quartile deviation, mean
deviation from median, variance, and standard deviation.
(e) Construct a box-and-whisker plot and comment on it.
Problem-2
Glomerular filtration rate (GFR) in pediatric renal transplant recipients has been studied by a
researcher. GFR is an important parameter of renal function assessed in renal transplant recipients.
Cystatin C is a cationic basic protein that was investigated for its relationship to GFR levels. In
addition, creatinine levels were also investigated for the relationship. The following data are the
measurements of GFR, cystatin C levels (mg/L), and creatinine (mmol/L) from 26 subjects. (Note:
GFR measured with diethylenetriamine pentaacetic acid.)
(a) Compute mean, and the five number summary for (i) GFR, (ii) Cystatin C and (iii)
Creatinine.
(b) Compute quartile deviation, mean deviation from median, and standard deviation for (i)
GFR, (ii) Cystatin C and (iii) Creatinine.
(c) Compare the variability of the measurements for Cystatin C and Creatinine. Which
measurements show more variation?
(d) Construct box-and-whisker plots for (i) GFR, (ii) Cystatin C and (iii) Creatinine.
(e) Find approximate percentage of the measurements is within one standard deviation of the
mean? two standard deviations of the mean? three standard deviations of the mean? by using
empirical rule (if applicable) or by any relevant theorem for (i) GFR, (ii) Cystatin C and (iii)
Creatinine.
Page 1 of 2
Stat H-101 (Introduction to Statistics)
(f) Find the actual percentage of the measurements is within one standard deviation of the mean?
two standard deviations of the mean? three standard deviations of the mean? for (i) GFR, (ii)
Cystatin C and (iii) Creatinine.
GFR Cystatin C Creatinine
18 1.78 0.35
21 2.16 0.30
23 1.82 0.20
27 1.86 0.17
27 1.75 0.15
30 1.83 0.13
32 2.49 0.14
32 1.69 0.12
32 1.85 0.24
36 1.76 0.16
37 1.25 0.17
41 1.50 0.11
42 2.06 0.12
42 4.69 0.14
43 3.78 0.11
48 2.24 0.09
48 4.93 0.12
51 2.71 0.07
55 1.76 0.12
58 2.62 0.11
60 2.61 0.07
62 3.65 0.10
67 2.36 0.13
68 3.25 0.09
88 2.01 0.12
63 2.51 0.06
Page 2 of 2