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Organic Reaction Mechanisms Overview

The document lists various chemical reactions and their corresponding reagents used for transformations in organic chemistry. It includes reactions for converting alkyl halides, alcohols, phenols, and carbonyl compounds into different functional groups. The document serves as a reference for synthetic pathways and reaction conditions in organic synthesis.

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0% found this document useful (0 votes)
10 views9 pages

Organic Reaction Mechanisms Overview

The document lists various chemical reactions and their corresponding reagents used for transformations in organic chemistry. It includes reactions for converting alkyl halides, alcohols, phenols, and carbonyl compounds into different functional groups. The document serves as a reference for synthetic pathways and reaction conditions in organic synthesis.

Uploaded by

ketanasree
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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AgF / Hg₂F₂ / SbF₃ / CoF₂ — Alkyl halides → Alkyl

fluorides swarts reaction​


AlCl₃ / CH₃Cl — Friedel–Crafts alkylation of benzene​
AlCl₃ / CH₃COCl — Friedel–Crafts acylation of
benzene​
Alcoholic KOH — Alkyl halides → Alkenes​
Aq. KOH — Alkyl halides → Alcohols​
AIH(i-Bu)₂ / H₂O — Nitriles → Aldehydes

B
BH₃ / H₂O₂ / OH⁻ — Alkenes → Alcohols
(Anti-Markovnikov)​
Br₂ / Cs₂CO₃ — Phenol → Monobromophenol​
Br₂ / FeBr₃ — Bromination of benzene​
Br₂ / H₂O — Phenol → Tribromophenol

C
CHCl₃ / NaOH — Phenol → Salicylaldehyde
Reimer-Tiemann reaction Cl₂ / Fe
or FeCl₃ — Chlorination of benzene​
Cl₂ / red P (HVZ reagents) — Carboxylic acids →
α-Halo acids HVZ​
Cl₂ / hv — Alkyl side chain chlorination​
CO + H₂ (Zn–Cr₂O₃, 200–300 atm, 573–673 K) —
CO + H₂ → Methanol​
CO + HCl / AlCl₃ (Gattermann–Koch) — Benzene
→ BenzaldehydeGattermann–Koch​
Cu / 573 K — 1° alcohol → Aldehyde, 2° alcohol →
Ketone, 3° alcohol → Alkene​
CuCl, CuBr, CuCN, KI, H₂O, H₃PO₂ — Diazonium
salts → Halo derivatives / CN / Phenol / Benzene
sandmeyer

D
DIBAL-H / H₂O — Esters → Aldehydes​
Dil. HNO₃ — Phenol → Mononitrophenol

E
Ether + HI — Ether → Alcohol + Alkyl halide

H
H₂ / Ni or Pd — Reduction of aldehydes, ketones,
nitriles → Alcohols/amines​
HCl / ZnCl₂ (Lucas reagent) — Alcohols → Alkyl
chlorides​
HBr, HI — Alcohols → Alkyl halides​
H₂O / H₂SO₄ — Alkenes → Alcohols​
H₂SO₄ (conc, 443 K) — 1° alcohols → Alkenes​
H₂SO₄ (conc, 410 K) — Alcohols → Ethers​
H₂SO₄ / HNO₃ — Nitration of benzene​
H₂SO₄ (conc) + ROH — Carboxylic acids → Esters​
H₃PO₄ (85%, 440 K) — 2° alcohol → Alkene​
H₃PO₄ (20%, 358 K) — 3° alcohol → Alkene​
HBF₄ / NaBF₄ — Diazonium salt → Fluorobenzene​
HCN — Carbonyl compounds → Cyanohydrin​
HOCH₂–CH₂OH / HCl — Carbonyl compounds →
Ethylene glycol ketals
Halogenation of benzene

I
Invertase — Sucrose → Glucose + Fructose​
I₂ / NaOH — (not iodoform test; reagent itself gives
alpha-iodination of methyl ketones)

K
KMnO₄ / KOH — Toluene or alkyl benzene →
Benzoic acid​
KMnO₄ / acid or K₂Cr₂O₇ / H₂SO₄ — Alcohols →
Carboxylic acids (oxidation)​
KOH / RX (Gabriel phthalimide reagent) —
Phthalimide → Amine​
KOH / CaO — Decarboxylation of acids → Alkanes

L
LiAlH₄ — Carboxylic acids → Alcohols; Amides →
Amines; Nitriles → Amines​
Lucas reagent (HCl / ZnCl₂) — Alcohols → Alkyl
chlorides

M
Mg + RX (Grignard reagent) + H₃O⁺ — Carbonyls →
Alcohols

N
Na — Alcohols or phenols → Sodium alkoxides /
phenoxides​
Na / dry ether (Wurtz) — Alkyl halides → Alkanes​
Na₂Cr₂O₇ / H₂SO₄ — Phenol → Benzoquinone​
Na₂CO₃ / NaHCO₃ — Carboxylic acid test (excluded
from tests list? you said remove tests; already
removed from this main list)​
NaOH / CO₂ — Phenol → Salicylic acid​
NaOH (fusion or hydrolysis) — Esters →
Carboxylate + Alcohol​
NaOH / heating with acids — Acids → Amides​
NaOH + CaO — Decarboxylation of acids →
Alkanes​
NaHSO₃ — Aldehydes & ketones → Bisulfite
addition salts​
NaNO₂ / HCl (0–5°C) — Formation of diazonium
salts​
NaOH — (pure base) used in many substitutions
(kept as given)

P
PBr₃ — Alcohols → Alkyl bromides​
PCl₃ — Alcohols → Alkyl chlorides​
PCl₅ — Alcohols & acids → Alkyl/acid chlorides​
PI₃ — Alcohols → Alkyl iodides​
P₂O₅ / P₄O₁₀ — Carboxylic acids → Anhydrides;
Amides → Nitriles​
PCC — Alcohols → Aldehydes​
Pd/BaSO₄ (Rosenmund) — Acid chlorides →
Aldehydes​
Pd/C + H₂ — Reduction (general)

R
RMgX + carbonyl / H₃O⁺ — Carbonyls → Alcohols​
(CH₃)₂Cd — Acid chlorides → Ketones​
ROH / conc H₂SO₄ — Esterification of acids

S
SOCl₂ — Alcohols → Alkyl chlorides​
Sn/HCl or Fe/HCl — Nitro → Amine​
Sucrose enzymes (invertase) — in list above
SnCl₂ / HCl / H₃O⁺ — Nitriles → Aldehydes
SOCl₂ / Pyridine — Alcohol → Alkyl chloride (if
needed)

T
Thionyl chloride (SOCl₂) — already included​
Toluene oxidation — Listed under KMnO₄

Z
Zn dust — Phenol → Benzene​
Zn–Hg / HCl (Clemmensen) — Carbonyl
compounds → Alkanes
Zymase — Glucose/fructose → Ethanol
……………..
‘’’’’’’’’’’’’’’
‘’’’’’’’’’’’’’’’’’’

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