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Understanding Dunnett's Test in Statistics

This document describes the Dunnett statistical test, which compares the means of several experimental groups to a control group mean to determine if there are significant differences. The test controls the error rate by making multiple comparisons to a single control group.

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0% found this document useful (0 votes)
22 views9 pages

Understanding Dunnett's Test in Statistics

This document describes the Dunnett statistical test, which compares the means of several experimental groups to a control group mean to determine if there are significant differences. The test controls the error rate by making multiple comparisons to a single control group.

Translated by

ScribdTranslations
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
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DEMOCRATIC AND POPULAR ALGERIAN REPUBLIC

MINISTRY OF HIGHER EDUCATION AND SCIENTIFIC RESEARCH

UNIVERSITY BATNA 02

Faculty of SNV

Department of Biology

Presentation on

DUNNETT Test
Produced By Written by:

UNIVERSITY YEAR: 2019-2020


DUNNETT'S Test

Introduction:

InstatisticsThe Dunnett test is a procedure formultiple comparison developed


by the Canadian statisticianCharles Dunnett to compare each of the treatments with a
single control Multiple comparisons to a control are also called comparisons
many-to-one.

Definition:

This post-hoc test (or multiple comparisons test) can be used to determine the
significant differences between theaverageof a control (test) group and the averages
from other treatment groups in an analysis of variance. The Dunnett test is
considered one of the least conservative post-hoc tests (for a presentation
detailed explanation of the different post-hoc tests.

History

The Dunnett test was developed in 1955; an updated table of critical values has
was published in 1964.

Multiple comparisons problem

The problem of multiple comparisons, multiplicity, or multiple testing arises


when considering a set of statistical inferences simultaneously or deducing one from it
subset of parameters selected based on observed values. The problem
major in any discussion on multiple comparison procedures is the question of
probability of type I errors. Most of the differences between alternative techniques
result from different approaches to the question of how to control these errors. The
the problem is partially technical; but it is actually much more about a question
subjective to know how you want to define the error rate and what is the extent that
You are ready to allow the maximum possible error rate.

Dunnett tests are well known and widely used in the procedure of
multiple comparison to compare simultaneously, by interval estimation or test
of hypothesis, all active treatments with a control during sampling from a
distribution where the assumption of normality is reasonable. The Dunnett test is designed to
maintain theequal family error rate you are inferior when making comparisons
multiples of the treatment group with the control.
Uses of the Dunnett test

The original work on the problem of multiple comparisons was done.


byTurkeyandSchefféTheir method was general, which considered all kinds of
pairwise comparisons. The Tukey and Scheffé methods allow for a number
any comparisons among a set of sample means. On the other hand, the
Dunnett's test only compares one group with the others, addressing a particular case of
multiple comparison problem - pairwise comparisons of several groups of
treatment with a single control group. In the general case, where one compares each of the
pairs, we make comparisons (where k is the number of groups), but in the case of treatment
regarding the witnesses, we will only make comparisons. If in the case of the groups of
treatment and control we had to use the more general methods of Tukey and
Scheffé, they can lead to unnecessarily wide confidence intervals. The test of
Dunnett takes into account the special structure of treatment comparison at
control, which gives narrower confidence intervals.

It is very common to use the Dunnett test in medical experiments, for example
by comparing the blood formula measurements in three groups of animals, one of which
served as a control while the other two were treated with two medications
different. Another common use of this method is among agronomists: the
Agronomists may want to study the effect of certain chemicals added to the soil on
crop yields, they will therefore leave some untreated plots (control plots)
and will compare them to the plots where chemicals have been added. the soil (plots of
treatment).

Official description of the Dunnett test

The Dunnett test is performed by calculating aStudent's t statisticfor each group


experimental or treatment, where the statistic compares the treatment group to a single one
control group. Since each comparison has the same common control, the procedure
Include the dependencies between these comparisons. In particular, the t statistics are all
derivatives of the same estimate of the error variance that is obtained by grouping the
sum of squares for the error across all groups (treatment and control). The
The formal test statistic for the Dunnett test is either the largest in absolute value of
these statistics t (if a two-tailed test is required), either the most negative or the most positive of
statistics t (if a one-tailed test is mandatory).
In the Dunnett test we can use a common table of critical values,
but more flexible options are now easily available in many
statistical software such asRThe critical values for any given percentage point
dependent: on whether a one-tailed or two-tailed test is performed; the number of groups
compared; the total number of trials.

Calculation

As Dunnett compares two groups, he acts in the same way as atest tThe formula
the following gives you a value that you can use to compare the differences
averages. The formula is:

Need help?Check out our tutoring page!

Step 1: find the critical value tDunnettin theDunnett's critical values tableYou
you will need:

Youralpha levelchoose (generally 5%)

Sample size,n

Degrees of freedom by report on the ANOVA output "Within Groups". This concerns the
"n" in the left column of the table.
For example, let's say you have an alpha level of 5%, a sample size of 5 and 20.
df. The critical value of Dunnett is 2.65.

Plug the value into the formula:

Step 2: Find the mean squares (MS) of the group in the source ANOVA table. Plug in
this value in the formula above. For example, let's say your MS inside is
15.39

Step 3: Find "n", the number in a group. For this example, it is 5:

By solving the formula, we obtain:

DDunnett= 2.65 * 2.481 = 6.575.

The answer (6.575) is the critical distance between the means. If the distance between a
the average of a control group and the average of an experimental group is greater than
6,575, so this distance is significant. For example, let's say you had an average
of a control group of 52 and three means of an experimental group of 55, 64, and 72. The
Differences between the averages (absolute values) are:

Group 1 55-52 = 3

Group 2 64-52 = 12

Group 3 72-52 = 20

Only groups 2 and 3 exceed Dunnett's distance of 6.575, so they are the pairs.
significant.
Examples

Tensile strength of the fabric

The following example has been adapted from the one given by Villars. The data represents some
measures of the rupture resistance of the fabric treated by three different chemical processes by
in relation to a standard manufacturing method.

breakage resistance (lbs.)

the process process process


US standards 1 us 2 us 3

55 55 55 50

47 64 49 44

48 64 52 41

Want
50 61 52 45
dire

Variant
19 27 9 21
this
Conclusion :

The Dunnett test (also called Dunnett's method or multiple comparison of)
Dunnett compares themaveragesseveralexperimental groupsto an average
ofcontrol groupto see if there is a difference. When a testANOVAadesresults
significantIt only reports which pairs of means are different. Dunnett can be
used after the ANOVA analysis to identify pairs with differences
significant.

A fixed "control" group is compared to all the other samples, so it should only be used
that when you have a control group. If you do not have a control group, usethe test
of Tukey.
The references

1.^ Upton G. et Cook I. (2006.) A Dictionary of Statistics, 2nd edition, Oxford University
Press, Oxford, United Kingdom.

2.^ Rumsey, Deborah(19/08/2009). Statistics II for the


nulls. Wiley. p.186Retrieved on 08/22/2012. Dunnett's test developed by.

3.^ Everett BS & Shrondal A. (2010.) The Cambridge Dictionary of Statistics, 4th edition,
Cambridge University Press, Cambridge, United Kingdom.

4.^ Statistical software | University of Information Technology


Kentucky. [Link]. Archived fromthe originalJuly 31, 2012. Retrieved on August 22, 2012.

5.^ Abc dDunnett CW (1955)."Une procédure de comparaison multiple pour


compare several treatments with a control Journal of the American Statistical
Association .50: [Link]: 10.1080 / 01621459.1955.10501294.

6.^ abDunnett CW (1964.) "New tables for multiple comparisons


with a control", Biometrics, 20: 482–491.

7.^ Abc David C. Howell, "Statistical Methods for Psychology", 8th ed.

8.^ Dunnett's testHyperStat online: an introductory manual on statistics and a


online tutorial for assistance in statistics courses

9.^ Mechanics of different tests - Biostatistics BI 345Archived the 01/06/2010 to


theWayback Machine, Saint Anselm College

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