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Important Biochemistry Questions 2024

The document outlines important questions for the Biochemistry course for the 2024-2025 batch at M.G.R University, divided into clinical questions, short notes, essays, and additional topics. Key areas of focus include metabolic disorders, vitamin deficiencies, lipid metabolism, and enzyme functions. The structure emphasizes both theoretical knowledge and practical applications relevant to clinical biochemistry.

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98 views3 pages

Important Biochemistry Questions 2024

The document outlines important questions for the Biochemistry course for the 2024-2025 batch at M.G.R University, divided into clinical questions, short notes, essays, and additional topics. Key areas of focus include metabolic disorders, vitamin deficiencies, lipid metabolism, and enzyme functions. The structure emphasizes both theoretical knowledge and practical applications relevant to clinical biochemistry.

Uploaded by

praneshmass1kpm
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

BIOCHEMISTRY (2024-2025 Batch)

M.G.R UNIVERSITY BIOCHEMISTRY IMPORTANT QUESTIONS - PAPER-1

I. Clinical Questions (4 Questions)- 24 Marks

1. Galectosemia.

2. Obesity.

3. Von Gierke’s disease.

4. Fatty liver.

5. Lactic acidosis.
6. B12 deficiency causes Macrocytic anemia.

7. Dyslipidemias.

8. Atherosclerosis.

9. Hyperbilirubinemias.

10. Lipid storage diseases

11. Acute intermittent porphyria.

12. Congenital erythropoetic porphyria.

13. Jaundice of newborn.

II. Reasoning out short notes: - (10 Marks)

1. Deficiency of G6PD and pyruvate kinase causes hemolytic anemia.

2. Polyol pathway is implicated in the pathogenesis of diabetes mellitus.

3. LDL is called as ‘bad cholesterol’.

4. HDL is involved in the reverse cholesterol transport.


5. Von Gierke’s disease causes Lactic acidosis and Hypoglycemia but no splenomegaly and
muscle involvement. Reason out.

6. Deficiency of lung surfactant causes Respiratory distress syndrome.

7. Chronic alcohol presents with hypoglycemia and is always considered as source of empty
calorie. Reason out.

8. Vitamin D deficiency causes an elevated PTH and ALP.

9. Fructose intolerance presents with hypoglycemia and hypophosphatemia.

10. Acute intermittent porphyria patients does not have photosensitivity.


11. Blood sugar levels are regulated by insulin and glucagon.

12. Insulin regulates glycolysis and glycogenesis. Reason out.

13. High levels of LDL is associated with atherosclerosis.

III. Essay: (10 Marks)

1. Vitamin A Deficiency, wald visual cycle.

2. Discuss in detail the digestion and absorption of lipids.

3. Diabetic ketoacidosis, Ketogenesis and its consequences.


4. Beta oxidation of fatty acids.

5. Fatty liver.

6. Heme degradation, Hyperbilirubinemias and causes of jaundice.

7. Kreb’s cycle and anaplerotic role.

8. Mode of action of enzymes, factors affecting enzyme activity.

9. Oxidative phosphorylation, Chemiosmotic theory, Inhibitors of ATP synthesis.

10. Glycogenesis and Glycogenolysis.

[Link] and its regulation, Energetics.

12. Vitamin B9 & B12 deficiency.

[Link]- Regulation, Degradation products, functions and clinical significance.

[Link] C- RDA, sources, Functions and Deficiency manifestations.

[Link] B6 deficiency.

[Link] B1 deficiency.

IV. Write short notes:


1. Glucuronic acid pathway.

2. Gluconeogenesis.

3. Odd chain fatty acid oxidation.

4. Osazone formation.

5. Congenital hyperbilirubinemias.

6. Functions of phospholipids and ARDS.


7. Significance of HMP shunt pathway.

8. Anaplerotic reaction of Krebs cycle.

9. Marker enzymes.

10. Vitamins- Study all Vitamins (2-3 Q will come- Especially B1, B3, B6, B9 and C)

11. Glycemic index.

12. Therapeutic uses of enzymes.

13. PUFA and Transfatty acids.

14. Heavy metal poisons.


All the best

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