### **33. Who secretes testosterone?
**
- **Leydig cells** (interstitial cells in testes).
### **34. Which secrete Oestrogen?**
- **Granulosa cells** of ovarian follicles and placenta.
### **35. At bleeding phase, what is the status of oestrogen and progesterone?**
- **Both are at their lowest levels** (cause endometrial shedding).
### **36. Which hormone affects menses?**
- **Progesterone withdrawal** triggers menstruation.
### **37. Combined contraceptive pill contains which Hormone?**
- **Synthetic oestrogen + progestin**.
### **38. Effect of contraceptive pill?**
- Inhibits ovulation, thickens cervical mucus, thins endometrium.
### **39. Drawback of contraceptive pills?**
- Side effects: nausea, weight gain, increased risk of blood clots.
### **40. What effect occurs if gonads are removed as contraception?**
- **Sterilization**: Loss of gamete production and sex hormone secretion.
### **41. Write two parts of ovary**
- **Cortex** (contains follicles) and **Medulla** (vascular tissue).
### **42. Parts of uterus**
- **Fundus, body, cervix**.
### **43. Why do testes descend into the scrotum?**
- To maintain **2–3°C lower temperature** than body for spermatogenesis.
### **44. At what stage is the mammalian embryo implanted in the uterus?**
- **Blastocyst** (5–7 days post-fertilization).
### **45. Why does Cortical reaction occur?**
- To prevent **polyspermy** by hardening the zona pellucida after sperm entry.
### **46. Which part of Blastocyst is destined to become embryo?**
- **Inner cell mass (ICM)**.
### **47. What is Corpus luteum?**
- Temporary endocrine structure formed from the ruptured follicle, secreting **progesterone**.
### **48. Which Antibody can cross placenta and which is present in Colostrum?**
- **IgG** (crosses placenta); **IgA** (dominant in colostrum).
### **49. Site for Spermatogenesis**
- **Seminiferous tubules** of testes.
### **50. Which part of male reproductive system stores sperm?**
- **Epididymis**.
### **51. Which part of sperm helps to penetrate ovum?**
- **Acrosome** (contains enzymes to digest zona pellucida).
### **52. Where does fertilization take place?**
- **Ampulla of the oviduct (fallopian tube)**.
### **53. Where are Leydig cells located?**
- **Interstitial spaces between seminiferous tubules** in testes.
### **54. Which hormone stimulates development of corpus luteum?**
- **LH (Luteinizing Hormone)**.
---
### **Key Notes:**
- **LH surge** triggers ovulation.
- **Progesterone** sustains pregnancy; its drop causes menstruation.
- **Spermatogenesis** occurs in seminiferous tubules; **oogenesis** starts in fetal life.
Let me know if you need further clarification! 😊