REVISION TEST ---- PRINCIPLES OF INHERITANCE AND VARIATION
1. Two genes A and B are linked. In a dihybrid cross involving these two genes, the F1
heterozygote is crossed with homozygous recessive parental type(aabb). What
would be the ration of offspring in the next generation?
a) 1:1:1:1
b) 9:3:3:1
c) 3:1
d) 1:1
2. Mother and father of a person with blood group O have A and B group respectively.
What would be the genotype of both mother and father?
a) mother is homozygous for A and father is heterozygous for B group
b) mother is heterozygous for A and father is homozygous for B group
c )Both mother and father are homozygous for A and B group
d) Both mother and father are heterozygous for A and B group respectively.
2. Occasionally, a single gene may express more than one effect. The phenomenon is
called
a) Multiple allelism
b) Pleiotropy
c) Polygeny
d) Quantitative inheritance.
Mendel’s law of independent assortment holds good for genes situated on the
a) Non-homologous chromosomes
b) Homologous chromosomes
c) Extra nuclear chromosomes
d) Same chromosome.
3. In sickle cell anaemia, glutamic acid is replaced by valine. Which one of the
followinnng are triplet codes for valine?
a) GGG
b) AAG
c) GAA
d) GUG
4. If a genetic disease is transferred from a phenotypically normal but carrier female to
only some of the male progeny, the disease is
a) Autosomal dominant
b) Autosomal recessive
c) Sex-linked dominant
d) Sex-linked recessive.
5. State a difference between a gene and an allele.
6. Mention the type of allele that expresses itself only in homozygous state.
7. Why, in attest cross, did Mendel cross a tall pea plant with a dwarf pea plant?
8. In a dihybrid cross, when would the proportion of parental gene combination be
much higher than non-parental types, as experimentally shown by Morgan and his
group?
9. Write the type of sex determination mechanisms the foll: crosses show. Give an
example of each type:
a) Female XX with male XO
b) Female ZW with male ZZ
10. State the chromosomal defect in individuals with Turner’s syndrome.
11. A haemophilic son was born to normal parents. Give the genotypes of the parents
and the son.
12. Why is it that father never passes on the gene for haemophilia to his sons? Explain.
13. Why do normal RBCs become elongated sickle shaped structures in a person
suffering from sickle cell anaemia?
14. Name the inheritance pattern where both the phenotypic and genotypic ratios are
same.
15. How much is 1 map unit for expressing distances between genes on a chromosome?
16. What are linked genes? How many linkage groups are there in human
chromosomes?
17. Differentiate polyploidy and aneuploidy.
18. How would you find the genotype of a tall pea plant bearing white flowers? Explain
with the help of a cross and name the type of cross carried out by you.
19. Two independent monohybrid crosses were carried out involving yellow seeded pea
plant with a green seeded one. In the first cross, the offspring population showed
equal number of yellow and green seeded plants whereas in the second cross it was
different. Work out the crosses to show the difference.
20. Explain co-dominance, complete dominance and multiple allelism by taking a single
example.
21. Point out any two similarities in the behaviour of chromosomes and genes. Who
proposed the chromosomal theory of inheritance?
22. Why is pedigree analysis done in the study of human genetics? State the conclusions
that can be drawn from it.
23. A cross between a normal couple resulted in a son who was haemophilic and a
normal daughter. In course of time, when the daughter was married to a normal
man, to their surprise, the grandson was also haemophilic. Represent this cross in
the form of a pedigree chart. Give the genotypes of the daughter and her husband.
24. Name a disorder, give the karyotype and write the symptoms where a human male
suffers as result of an additional X chromosome.
25. Which chromosome carries the mutated gene causing b-thalassemia? What are the
problems caused by this mutation?
26. Both thalassemia and haemophilia are blood related disorders in humans. Write
their causes and the difference between the two. Name the category of genetic
disorder they both come under.
27. Explain two situations when independent assortment of genes occur, resulting in
50% recombination.
28. Sometimes a gene which carries a major disadvantage in homozygous state confers
an advantage in heterozygous condition. Explain by giving a suitable example.
29. During his studies on genes in drosophila that were sex-linked, [Link] found
population phenotypic ratios deviated from expected 9:3:3:1. Explain the conclusion
he arrived at.
30. One of the twins born to parents having normal vision was colour blind whereas the
other twin had normal vision. Work out the cross and give two reason to show its
possibility.
31. You are given a red flower bearing pea plant and a red flower bearing snapdragon.
How would you find the genotypes of these two plants with respect to the flower
colour. Explain with the help of crosses.
32. How are Mendelian inheritance, polygenic inheritance and pleiotropy different from
each other?
33. In drosophila 2n=8, how many linkage groups are there?
34. Dihybrid cross between two garden pea plant-one homozygous tall with round seeds
and the other dwarf with wrinkled seeds was carried.
a) Write the genotype and phenotype of the F1 progeny obtained from this cross.
b) Give the different types of gametes of the F1 progeny.
c) Write the phenotypes and its ratios of the F2 generation obtained in this cross
along with the explanation.
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