Scribd
Upload
4 views18 pages

MC 2 Assignment

Mc

Uploaded by

ponnapallavi430
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF or read online on Scribd
4 views18 pages

MC 2 Assignment

Mc

Uploaded by

ponnapallavi430
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF or read online on Scribd
MEDICINES CHEM SMa MiD-it ASSIGNMENT ANTI DinpeTic AGENTS ogni which ore useol in Lhe Aaalment Aiabebes axe called 2s anticliahelc ts. ro ued to Lower He ALoodl Patients suffering from hyperglytonic. Nee? kkndwn as Anti- hyperglycaremc ogenli : Diabetes mellitus : Tt 3s a chvonic melabylic olisoader usich Ps, chorasterized fy peg (Increase blood Sugon Newel): val Symplorns : , Hy) a a Poly dipsta (Gecens-theaat) Fc Polyphagia. (exter burger) > poty wren (exes usinako) . devel ai | | Diabetes melbtes ot os on at my Pelle (toulin Depenolount (won -insakin Spans Diebetes melita) Diabetes mellitus ) observed tn guwensle > Meo calle! Aotult ore entel pm: j Dm. Ako kle Juxenile onset dM obsewed *n Actults | © scanned with OKEN Scanner chassificasion 5 I) Insulin g, ts prepasat’on s er ieee es 1 a ita iG mars sane > pactascint Zin = Lispxo SLA. > Vike fente 4nrauin Zinc i We ae . — Biphasic = Insulin gion mae ep Goalie coped 3 Artalin deb’ —hnsulin doqtudle- 1) deed Aupogfiycoeroic. agent 2) fyonyl was: j 8 ao cnesation: Tethilamide 1 chlor opornide and enesahon: Glibendoride i Glpizde p)meglitinides : Reperglinide alog inide C) Thazolidine clones: Reseig lita zone, Pioglitazone. d) ol- Glusosidase trbhibiters ; Acosbose suo’ b9S° ; ©) Biquanides: phenforrnin, Dine oan } T) “Tasahia & ts preparasions Y ghoat aauking ansetin prepoxodion 4 aR Snsulio: a | Alo cabled -04 newteol or Soluble a ess => Rapid ating wsith os —[hY [Link] > p) dispro dnsecbin. . f Bes auting with 6-8 hes lurotion a awh On. | ae beer eke ay p roe 3 one guesd: © scanned with OKEN Scanner 1S a ketombinant Auman frsul'n 3 [DAnsillir gine: Al is a Gunpension saselin § 2nd - gl Bhis olurodion of axhion- I) Snsutin : feprthe form of Auman rasan where a Sirgle amino id, pantine (B-28) is Aaploved by aAparttic avd: “Shy cluxahion ation Dantewwediote avting | 4 sophone fagetin: |? Abo called os neutzal protarsine agen dupt) fnsutin. PIS- M4 be clwotion gf auhion: ' oo ermposed 4 20, Probarnine g regalo Saude : Al Lente Insun’. ia ERA s dusotiony aula. Re a, Ou € by] ,2ne& deglan insulin ) Biphasic insulin aspant! By hr- clusiadton of action. E: o Be). soluble insalio Be Aol profararng hound enculin at Jtong ung - a) Paotamine Binc inguin: > twompaced! 4nsulin znd & Proton nine 3b hes- duxolion of on™ |b) Ultra Lente ensubin: Sntotns 65% of Lente insultn } 936 hrs- clusation af aiken | © scanned with OKEN Scanner C)4nsutin glovigine: y > oblained by aclolitron et +4wo sotne sesrdues ip B- chain conthony Hexmnins! e by eee al 4 ae usth alive to Repinsepeny 4 [Link] woth aa kell ro A-21 Pedition of human fnsulin > 24 ks - oluiation 2} action. 3) Insulin deberni«! | ! Mi obtained by alot’ tron fo cee lraysistre aid) to Aysine Residue in B-94 position a insulin i > Ty hy- curation Sane : €) Insubin Aegludee! 1 1 Al 1 spin ! = obtoined adoltoo 4 Aeneid erprectiec aesidue in 8-29) positon hatha fowl . — B44 bs- duration 4 sa Bi) ova) upoglytacnnic caents) \oly Vy EY eae es first med oval Asipogti tas -emic agent sed {ox treatment Hicieh eee stheg ane also called os fnsulin [Link] | i acy hilo Sar eniecaal 1 Hq ri carbutamide- Mor Sathey bind to the Sulfony] urea. £e6 tors. present in pantaeahe- pec. Me Jeoals +o as he beth ke channels and) deprtarizes the f3-cell membrane ‘Then it opens voltage goted tot? onnels and stirnulates B-cells to herete more insulin. © scanned with OKEN Scanner Sadphenul ucneos ohe grouped ms follows: Ss 1% generation : ehlorp roparnide, Tolbubamide, Acetchexamicle gw genexalion < GLibendtamide, GLipizide + guy buside x jenesation « Glimepividle Bangs 9 sauyony | Lseo's “pute ry Lown Baw -CyH9 Sycthaxis 7 ee oH + US0Q0% Hic 5 cH ame a d Toluene suijeore HN Hz ouid -ud q Me m INGA a 1) | gel Cesta ac BE) SON! each ey nado dig ZO soant Cant- ea. CH CHa 3 Tol buternide - Mon Pancacasic f- cell | Insuin acdeare | | | s 4 ca : cot channel - ne nh See cat 4 utose J i Sa Ms FTP chased | | | on | | G Ae Ly 6 4 '" eal P| sulfonylurea © scanned with OKEN Scanner they Aind 4o+he Sulgony/ ree. Aecephors Present iin, Panneatic B-cells. Ht eats Xe closure ef ATP- Sensitive } ct channels & dlepolazrises the B-cell membronne -Then it Gee Voltage ated cat? channels 9 SHmulotes B-cells to Seuck More 7nsulin S29 ae fox conkeolling Alood gfldiate $n previonsly untreated IN Used $n the treatment of cliabeles which vernates ASST ~Erotled even asien proper diet Used aso dubstitute for other oval hypoglycemic agert ch i Hapeportde AEN Cn CHa Haas Mor "i they bind +o he 4etforyy! Urea Aeceptors Paesent in Pancreatic B-cetls. 1 Jeaols to Losure of ATP sensitive k* channels -¢ depoloxizes the f-cell memlprone Then if opens votlege géled co+2channels & Sfinnulales pr-cells to sercte Morne ingutin Use — 4 is token with a Pope diel a awe (Le for usdrotling sigh Aload ugar in 4ype o diabetic patients - Used 0s on adlfund fo other olinbeter olauegs- © scanned with OKEN Scanner Uses PP Used wcith inswhin fox treating the perk dabdeu melbilius Biguacices ee, enol used Af joles axe ph Osun andl rn ‘OT Min They ¥ the bhood gfusose devel in diobelic « > Potients ay pole trading -the bypergtyceenic auton a tnsthen They ohio + he used fr trenton oe Polyeystre OVO OND TaN © scanned with OKEN Scanner Thtagot iolineoones 8 > THagolicineationes (Teds ov gltagone) aut by aeclusing the Tosutin resistance whith ts a common psoblero on mony snoltvid! —uoks powing pe: dobabeles. > Alow insulin +o pperkive Tmprove the blood givtese Levels by decreasing he Le alo xecliue Pe BP and fmprove Aipid metabolism a fovrearsing she Yevels of He cholesterol - Moa , They binds to andl dfimulates perorisonne pact caced Ativaled eveptox—7 Upped) due oo whith hey atvo Knovon Os prag-9 nists - ‘ > They increase the expaersion 3 tue %GLuT-4 Receptors m Once Suslore to Intacase Se uptake - 7h Reollee Engin Resistance ond ao 7 V the post- cial glucose Aewel e coi ees Pig [tdagone cas Uta “tha 0-)- Ua PF 3. td Uses e Used as an cxcljunce 40 olfet ond euceatie for paar Wycoemnic control individuak pournot Rosializazone E> y-de Mean Pa 6 Luwoneo ems HbAIC Uses >Used as an aoljunl to diet and euensise pr Teaproving the AWd4raemic Usntrol in inolividual having TyPe-2 DM © scanned with OKEN Scanner ——————— lhl a Meglitinides the ohwituce 4 megdihinides 5. Siento jo tha of sulyoruy{ Ma uae jnsulin secretngrpe > Repaalinide iS O New Nor- subpho nyt ne es" nide 73 another newest app meali Mor EES EE ay chi etr Lecay hd Same 24 thot o siugonsurcc. megliHnide me fi yeu — C2 oH i a CHa Olas U3, Uses used as on ole Pe A, eterist for Fenproving Ooemnrc Asglaten in 2ndiividuels hawirg a -2 DM. Nategliaide U i Wisedien Seaacnc gement | tepe-2 Dea (dusosidase thhibitor sbhibitors the od- sralare inhibitors Bre oct ee em Used fox treating type 2-9 OM by inhi ibiting ae yal ee PO au ataxch ‘ond fable secqox “ 3 i contohydiate s one donventec tone , ° in 7 cul hat von be absorbed tn the intestines: i. lassi J © scanned with OKEN Scanner 1 od-gluuosiolase tahibrtor chugs ae ced fo the Her" | carbohy drake on blooal Aegan Mon a A othe absorption ane! mefebatrin 4 cone 4s te3 by in thing v-glucosidase enigeme found inne bah bse boadex epitielim env tntestine - a Pt-qluresidare helps rh ging p ouhosides Aiqosauhosites indo hu), a Bis foe eirs absoaphion. These chugs prockiexe o-nti-hypergly caemte afer but ole | not Proclute hypedjenennra x Acoxrbose HOW,C Hse. Hoy, Hole Ke tae : ok, 40 Ny oH lor Silene eet USes ha Stked for treading type be fo corabirvadtion thevopy abo Kererd ox thiad tine agent | eee 4 on CH204 : les f j Uses Choy 7 f ‘ , usd fon treating Diabetes mallihes 2 Modaly it 1s age dewaxing post pAarolied blood th fe Aevels, hence pre Aik 4 [Link] Clos complica. —t0ns a © scanned with OKEN Scanner | Cosi [Link] ) Bengore aud uters: Cocoine , Heuleoine, mepry! caine eyclamediry 2z®) Pipexocaine- Benzo Coune, Budornber, 2) p_proinobezoic axtd esbers « pavcosne, Butatoine - ; w ‘ ie Hy —<>>~ C00 (9 4s ca(uta)36-<)- Cota ae 3 Bengotaine M Butamben i ° OE Hon Sfoutautang : % ‘SH cH procaine « \ 2) Amide /Avilide dlesivatives - groaine|Jaetaon/ipncea | Mepivatosne )Prilolatre, Ehidovaine- 3 o Ue 3 3 0 é Sn bata ac. H3 he «ou io i | 3 Barwaine ! Mepivatesne u) miscellaneous agents Araidine dedvative : Phenocadne ph conbarnati cLalvalives ‘Bipexoton Ausnebine Botivahves 3 Sibdectne. cous caus Bn ca Ha NE | es 3, “Dibuarne - © scanned with OKEN Scanner Local ANAESTHETICS : i otere one eit, Which upon Epica ap plitaHon on loca} Infeckion a aevetible Loss y pain wersation in a Ls) the : : op iy Hein both Sorsoay and rnotor nerve Cxnolic To" fo pagclure temporary Aes of Serkation yatthout Less 4 Consiousnes- Yon ~SThese chugs aeuersibly Prevent the erusadion and Pepeg “Adion of erpulses jn oll exuttable membiares intending, Neaue fide ay Hobiliging he enh sane. | Shey block the newe Leclieton by dlertensing he enky a: No* Si ton potential ge tN vt Rereplor Sfuated vaithin He vottog e phy. Not (banned Ande Ne Aheesheid 4 not chanrul ne, nlat gan’? enter into the cell in nse fo an se uotich patents depolargeton- Thus, oxtion potential not s Sey, Perporans peliey of Localized Pain, Bein cul fo entnor buans, faset bites & allesgy Jinoy mung and jn dentistey: © scanned with OKEN Scanner Lignocoine Diljuses Hsvsugh ae cell membrane - Binds voltage goled Nat channe/ Blocks not eftbuy Sato the cetl. Paices the Abawbotd pr exxitasion No quissetion 9 gmrclushion f Achion potental Peal Anacsthero. Sar of dete) Anoesthetio J exter deutvalives: fimiety SS Was x. —Aminoalky| ydeophobic Wate Av : ot wee chasn. roorely ayareptob (a ence a electxon usithdroswing at and positren 07 pavides td ons ation. Pb Ky Pal sol iN ation berause Onlascepsotaine. © scanned with OKEN Scanner ™ Se PESO Sd | ae i” imports rece dipid Sodusility & good absorpiron a oO H3 is ONS cha Cue z t ae Tetounine: ‘) Ara eeup- 4t ts odttorhed olinerty qothe coxrbony | moi ri , f \ Peenjugation ovtomahe rootety with carbonyl eat } enhances Load anaesthetic autivity | , — Substituents like arnino, ethoxy, athe] enna sal im tnereare Re olestron density on carbony! 09% enor the activity . ue | = noel te fa bh eau! im InawVe compar W) Baldge x-* mm be €,0,N0aS Anoestheh'c poten 2 g>0>0>N a Amides (x=) ore ie ae ey ) Yearno | _ Tertiary amines have a al soaker, hte bay a tanitating shen pu “a Oxnines: Atk ere also Mine ane Aid : \ aAroide dletivadrves: | | Ne | J Genexol Hhuitune: ii | ‘ | ae Es £, Lorbonyl aes | wl ; \ -NH-b-Aning olkey) , Moe These axe exentially onilide clesivosives Autry quod i 4 © scanned with OKEN Scanner r Naw) Beep phenyl yup 1s attpthed ta re |S \octom xough nitengen byidge: ; Be Suthotie ton of Phenyl yop wath, o melt! in 07 fe Position enlwonces he astiyi ah at pode, ope? y PAs steric Aindwonce to Ay otysrs 4 ay Ta Do coeyitient olis ibubion Pe i. eb the arnide oli! group - Gt is the hydhp Mie. Pe helps fn galt foxsoation « t = 1G SP arine, axe mone igattating “thos F omnes Covoine oan ses Ly bo tay Bised 04 onveshne fon “4: bon nog 2tacott B43 Ue ie t i 3uUsed as onoesthesia . gh Aw rit a leone ° it U3 Likes Fes bn -cty-Cha-dtg, Used a dando j | enous. - 3 Hy cosine i e Uses i So > b-0-Wg-Ho-H2- x) sued as tepid a \ On onnesthyio. | LOU (ye t \ © scanned with OKEN Scanner ewnzocaine cea & Boye L esused 4o Aeolue Paro dus to 4unbuin, teeth pain, Piles, Vagined | sudo4 How < \-Cooga Hs 1 aa3daHon gyntheris | <> O18 Rafe” ORY TK? eusadion” an Used 2s epfolural and newe blok antesthesro- Use suUsed for teilhosvon, — rou -CHy 2 U4 . i rf é newe block anastasia. uss

You might also like