Has Disease Healthy (No disease)
Tested +ve 80 → TP 20 → FP
Tested -ve 10 → FN 90 → TN
1. What is the sensitivity of the diagnostic test for detecting the disease?
Sensitivity: Proportion of truly diseased persons identified by screening test = TP/(TP+FN)
Sensitivity = 80 / (80 + 10) = 0.889
Therefore, the test correctly identifies 88.9% of people with disease.
*Near high sensitivity.
2. What is the specificity of the diagnostic test for detecting the disease?
Specificity: Proportion of truly non-diseased persons correctly identified= TN/(TN+FP)
Specificity = 90 / (90 + 20) = 0.818
Therefore, the test correctly identifies 81.8% of people who have no disease (healthy).
*Near high specificity.
3. What is the positive predictive value (PPV) of the diagnostic test?
Positive predictive value: Probability that a person with a positive test has the disease= TP/(TP+FP)
PPV = 80 / (80 + 20) = 0.8
Therefore, when the test result is positive, there is an 80% probability that the person actually has disease.
4. What is the negative predictive value (NPV) of the diagnostic test?
Negative predictive value: Probability that a person with a negative test does not have the disease=
TN/(TN+FN)
NPV = 90 / (90 + 10) = 0.9
Therefore, when the test result is negative, there is a 90% probability that the person truly is negative for
the disease.
*Formulas and data received from HSS3110 Lecture 7 Slides