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Immune System Overview and Functions

The document outlines key concepts related to the immune system and infectious diseases, including definitions, immune responses, and the differences between innate and adaptive immunity. It details the roles of various immune cells, the structure and function of lymphoid organs, and the mechanisms of phagocytosis and opsonization. Additionally, it discusses the clinical implications of normal flora and the conditions under which they can become pathogenic.

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Ali Jutyar
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0% found this document useful (0 votes)
7 views2 pages

Immune System Overview and Functions

The document outlines key concepts related to the immune system and infectious diseases, including definitions, immune responses, and the differences between innate and adaptive immunity. It details the roles of various immune cells, the structure and function of lymphoid organs, and the mechanisms of phagocytosis and opsonization. Additionally, it discusses the clinical implications of normal flora and the conditions under which they can become pathogenic.

Uploaded by

Ali Jutyar
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Lecture 1

o What are the factors determining the outcome of the host


pathogen relationship ?
o What is the definitions of immune system and infectious
disease ?
o Describe shortly about the immune response
o The difference between the innate and adaptive immunity
o What are the first line of Defence And numerate the types of each
one
o Example of the normal flora in the skin and the nasopharynx
o When the clinical problem start with normal flora
o What are the common cause of harmless bacteraemia
o Which patients have high risk of serious infections
o Give examples of the displacement of the normal flora
o When the normal flora overgrows and becomes pathogenic
o When the normal flora is depleted by antibiotic
o The main phagocytes cell and their functions
o Others cell of innate immunity and their functions
o What are the PAMPs and PRRs
o Examples of microbial PAMPs and PRRs
o What is the opsonisation of microbes
o Examples of opsonins
o Which type of microbial are essential to be opsonising and give
examples
o Definition of Phagocytes
o Phase of phagocytosis
o What are the phagocyte mechanisms for intercellular killing and
by which they killing it
o What is the 2 activating pathways for complement system
o Most important serum protein in complement system and the
functions of them
o When the clinical problems start with reduced phagocytosis
o Why is is called adaptive immunity
o The specificity of the adaptive immunity
o The types of adaptive immunity
o The T lymphocytes and explain them
o Difference between the humeral and cell mediated immunity
o The types of the extracellular microbes combated by T cell
mediated immunity
o The ways of acquired the immunity
o What is the naive B cell and it is fiction
o The functions of the antibodies
o The types of APCs with their location and presenting cell
o The feature of APCs

LECTURE 2
o Structure of the immune system
o The functions and origin of the leukocytes
o What is the categories of leukocytes explain and numerate the
cells of each one
o The categories of innate cell and numerate the cells of each
category
o The major types cell in the immune system
o Origin of the leukocyte
o What is the lymphoblast
o The size of lymphocytes
o The function of the CD4+ and CD8+
o The origin of the macrophages
o The functions of macrophages
o Dendritic cells origin and function
o The structure of these cell performing various functions
o The function of polymorphs and mast cells
o The classification of the lymphocytes
o Recognition and immune response dependence of lymphocytes
o The responding of the B lymphocytes
o The percentage of the T lymphocytes of blood lymphocytes
o The responding of the T lymphocytes
o The functions of helper cells
o The functions of killer or cytotoxic T cells
o Regulatory T cells
o The function and percentage of the NK cells of lymphocytes
o NK cells vs T lymphocytes
o Cell and function of APCs
o Numerate the primary and secondary lymphoid organ
o The structure of the thymus
o The activation of T helper and B lymphocytes
o The structure lymph nodes
o The blood suppling of lymph nodes
o The transferring of mature B cells
o What is the GLAT and they found in where
o The main places of spleen and there function with structure and
containing

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