DRUG STUDY Name of Drug Piroxicam (Feldene) Classification Indication Action The anti- inflammatory effect of Piroxicam may
result from the reversible inhibition of cyclooxygenase, causing the peripheral inhibition of prostaglandin synthesis. The prostaglandins are produced by an enzyme called Cox-1. Piroxicam blocks the Cox-1 enzyme, resulting into the disruption of production of prostaglandins. Piroxicam also inhibits the migration of leukocytes into sites of inflammation and prevents the formation of thromboxane A2, an aggregating agent, by the platelets Adverse Reaction Rash Headaches Dizziness Drowsiness Abdominal pain Nausea Constipation Fluid retention Ringing in the ears Photosensitivity Intestinal bleeding Ulcers Stomach ulceration Contraindication Nursing Responsibilities
Non-Steroidal Piroxicam is used Anti-Inflammatory primarily for the Drug (NSAIDs) treatment of rheumatoid diseases.
Piroxicam should not be used Administer to patient in patients who have whole; give with food previously exhibited or milk to decrease hypersensitivity to it or in gastric symptoms. individuals with the syndrome Instruct patient to comprised of bronchospasm, avoid aspirin, alcoholic nasal polyps, and angioedema beverages, and other precipitated by aspirin or over the counter other nonsteroidal antimedications unless inflammatory drugs. approved by the physician. Instruct patient to use caution when driving or performing activities that require alertness because drowsiness and dizziness may occur.
Name of Classification Indication Drug Ciprofloxacin Anti-bacterial For the treatment of the following infections caused by susceptible organisms: urinary tract infections, acute uncomplicated cystitis, chronic bacterial prostatitis, lower respiratory tract infections, acute sinusitis, skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections (used in combination with metronidazole), infectious diarrhea, typhoid fever (enteric fever), uncomplicated cervical and urethral gonorrhea, and inhalational anthrax (post-exposure).
Action The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, strand super coiling repair, and recombination.
Adverse Reaction Nausea Vomiting Stomach pain Heartburn Diarrhea Feeling an urgent need to urinate Headache Hives Difficulty breathing or swallowing Hoarseness or throat tightness Rapid, irregular, or pounding heartbeat Fainting Fever Joint or muscle pain Unusual bruising or bleeding Extreme tiredness Lack of energy of appetite Seizures Dizziness Confusion Nervousness Restlessness Anxiety Difficulty falling asleep or staying asleep Pain in the upper right part of the stomach Yellowing of the skin or eyes Dark urine
Contraindication Ciprofloxacin is contraindicated in persons with a history of hypersensitivity to ciprofloxacin, any member of the quinolone class of antimicrobial agents, or any of the product components. Co-administration of ciprofloxacin with other drugs primarily metabolized byCYP1A2results in increased plasma concentrations of these drugs and could lead to clinically significant adverse events of the co-administered drug. Contraindicated for the treatment of certain sexually transmitted diseases by some experts due to bacterial resistance. Concomitant administration with tizanidine is contraindicated.
Nursing Responsibilities Prevention or treatment of infection; signs and symptoms of infection like fever and pain are reduced. Make sure to drink plenty of water or other fluids everyday while taking Ciprofloxacin. Do not take or eat a lot of caffeine products such as coffee, tea, energy drinks, cola or chocolate within 6 hours before or 2hours after you take ciprofloxacin. Tell patients that antacids and mineral supplements may decrease the absorption of Ciprofloxacin which makes it less effective when taken at the same time.
Name of Drug Salbutamol Neb
Classification Anti-asthmatic
Indication Relief and prevention of bronchospasm in patients with reversible obstructive airway disease. Inhalation: treatment of acute attacks of bronchospasm. Prevention of exerciseinduced bronchospas m. Unlabeled use: adjunct in treating serious hyperkalemia in dialysis patients; seems to lower potassium concentrat ion when inhaled by patients on hemodialysis.
Action
Adverse Reaction
Contraindication
Nursing Responsibilities
In low doses, acts Feeling Shaky relatively selectively at Headache beta 2 adrenergic receptors to cause broncho dilation and vasodilation; at higher doses, beta 2 selectivity is lost, and the drug acts at beta 2 receptors to cause typical sympathomimetic cardiac effect.
Contraindicated with Use minimal doses for hypersensitivity to minimal periods; drug albuterol; tachy tolerance can occur with arrhythmias,tachycardia prolonged used. cause by Maintain a adrenergic digitalis intoxication. blocker (cardio selective Use cautiously with beta blocker, such diabetes mellitus; asatenolol, should be use hyperthyroidism, history with respiratory distress) of seizure disorders. on standby incase cardiac arrhythmias occur. Prepare solution for inhalation by diluting 0.5ml 0.5% solution with 2.5ml normal saline; deliver over 5 15 minutes by nebulization. Do not exceed the recommended dosage; administer pressurized inhalation drug forms during second half of inspiration, because the airways are open wider and the aerosol distribution is more extensive.
