NUCLEIC
ACIDS
NUCLEIC ACIDS
Nucleic acids are large biomolecules, including
DNA (deoxyribonucleic acid) and RNA
(ribonucleic acid), that store, transmit, and
express genetic information in living organisms.
They are composed of nucleotide monomers,
which consist of a sugar, a phosphate group, and
a nitrogenous base.
The building blocks of nucleic acids are nucleotides.
Each nucleotide consists of three components:
Sugar – A five-carbon sugar (deoxyribose in DNA,
ribose in RNA).
Phosphate Group – Links nucleotides together to
form the backbone.
Nitrogenous Base – Can be adenine (A), thymine (T,
only in DNA), uracil (U, only in RNA), cytosine (C), or
guanine (G).
molecular structure
NUCLEIC ACIDS were first isolated from the nuclei of
white blood cells by FRIEDRICH MIESCHER in the
1860s. The origin of the name nucleic acid came from
“nuclein,” the term used by Miescher to describe a
weak acidic substance that he found in the cell nuclei.
Just like the other biomolecules, the nucleic acid
structure is composed of the elements CARBON,
HYDROGEN, OXYGEN, and NITROGEN but it DOES
NOT CONTAIN SULFUR.
DNA RNA
DNA (Deoxyribonucleic acid) DNA (Deoxyribonucleic acid)
and RNA (Ribonucleic acid) and RNA (Ribonucleic acid)
definition are nucleic acids that store are nucleic acids that store
and transmit genetic and transmit genetic
information. information.
stores genetic
Job and role helps synthesize proteins.
instructions
double-stranded and single-stranded and more
Unique Features
stable flexible.
Predominant Structure forms a double helix usually a single strand
DNA RNA
has thymine (T) and
Bases and Sugars has uracil (U) and ribose
deoxyribose
Pairing of Bases A-T, C-G A-U, C-G
more stable due to its more prone to
Stability
double helix degradation
RNA is transcribed from
replicates before cell
Propagation DNA for protein
division
synthesis
Our DNA comes from our biological
parents. We inherit half of our DNA
from our mother (via the egg) and half
from our father (via the sperm). This
genetic material combines to form a
unique set of instructions that
determines our traits, such as eye
color, height, and even some aspects
of our personality and health
Our RNA comes from our DNA. It is
synthesized in the nucleus through a
process called transcription, where a
specific section of DNA is copied into RNA
by an enzyme called RNA polymerase. This
newly formed RNA then moves to the
cytoplasm to perform its functions, such
as protein synthesis (mRNA), amino acid
transport (tRNA), and ribosome formation
(rRNA).