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Understanding Collagen Synthesis & Disorders

Collagen is the most common protein in the human body, primarily found in skin, ligaments, muscles, and other tissues, serving as a major structural protein. It consists of various types, with Type I being the most prevalent, and has a unique triple helical structure that provides significant strength. The document also discusses the synthesis, degradation, functions, and disorders related to collagen.

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3 views7 pages

Understanding Collagen Synthesis & Disorders

Collagen is the most common protein in the human body, primarily found in skin, ligaments, muscles, and other tissues, serving as a major structural protein. It consists of various types, with Type I being the most prevalent, and has a unique triple helical structure that provides significant strength. The document also discusses the synthesis, degradation, functions, and disorders related to collagen.

Uploaded by

daraderiya
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

COLLAGEN SYNTHESIS

AND ITS
ABNORMALITIES

ROLL NUMBERS : 21-30


TABLE OF CONTENTS

01 Introduction 05 Degradation

02 Types 06 Functions

03 Structure 07 Disorders

04 Synthesis
INTRODUCTION
TO COLLAGEN

Most common protein in the


human body

Found in : skin, ligament,


muscle, tendon, cornea, hair
and nails

Present in all tissues


INTRODUCTION
TO COLLAGEN

It is the major structural It holds together the cells in


protein the tissue

Scleroprotein

Highest concentration is found in skin


it is more than that of in cornea
TYPES OF
COLLAGEN

Type I - Bone, Skin, Ligament, Tendon Type 10 - Hypertropic Cartilage


Type II - Cartilage Type 17 - Hemidesmosome
Type III - Aorta Type 19 - Rhambdomyosarcoma
Type IV - Base membrane
STRUCTURE OF COLLAGEN

tropocollagen is the basic structural unit


of collagen
it is made up of three polypeptide chains
each consists of 1000 amino acids
glycine is abundantly present
STRUCTURE OF COLLAGEN

Highly organised
Contributing to its strength
and function of connective
tissue
All collagen have triple helical
structure
more strength than steel

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