School Lorenzo Tan National High Grade Level 10
School
Student Teacher Prien Mae A. Bandiala Learning Science 10
Area
Teaching Time Quarter 3rd
I. Objectives
A. Content Standards
B. Performance Standards
C. Learning Competencies/objectives D. Describe DNA Replication
E. Identify the key players in
DNA Replication.
F. Explain the process of DNA
Replication.
II. Content/Subject Matter DNA Replication
III. Learning Resources
A. Teacher’s Guide Pages
B. Learner’s Material Pages
C. Textbook Pages
D. Additional Materials from Learning Resources
IV. Procedures 4 A’s
Teachers’ Activities Learners’ Activities
A. Preliminaries
a) Greetings
Good Afternoon Class!
How are you today? Good Afternoon Ma’am!
We’re Good Ma’am!
Kindly stand for the opening prayer.
Denver, kindly lead the opening prayer
Kindly stand for the opening prayer.
Denver, kindly lead the opening prayer. Our Father, Who art in heaven, Hallowed
a) Prayer be Thy Name. Thy Kingdom come, Thy
To start our class, kindly stand for the Will be done, On earth as it is in Heaven.
opening prayer. Please lead the prayer
Give us this day, our daily bread, And
Steven
forgive us our trespasses, as we forgive
those who trespass against us. And lead
us not into temptation, but deliver us
from evil.
b) Classroom Management
Alright, before you have your seats
kindly pick up the pieces of papers or
any garbages under your chairs and
align your chairs properly. Students settle down
You may now have your seats.
c) Checking of attendance No one si absent today Ma’am!
Alright, who is your class monitor? Who
are absent today?
Wow, it’s nice to hear that everyone Students are clapping
are present today!
Everybody clap your hands.
B. Motivation
ACTIVITY TITLE: 4 PICS 1 WORD
Let’s play a game called 4 Pics1word. I will
present four pictures and then you are going
to guess what word fits with 4 photos.
DNA
Photo Presented
Relplicate
Yes! You have guessed it right.
Now, when you hear about the word DNA what
comes to your mind?
Its an information ma’am that tells who
Yes, that’s correct! It has something to do on we are.
how we become who we are.
Okay, what do you think is the idea behind the
pictures I flashed earlier?
Copying DNA ma’am
C. Activity
Let’s have an activity. First, I have to divide this
class into two groups.
This row will be group 1, the second row will be
group 2.
Our activity is called “ DNA MAKES DNA
”
Everybody read the Directions
DIRECTIONS:
In 3 minutes, match the 4 nitrogenous bases DIRECTIONS:
to their perfect pair and paste it on the In 3 minutes, match the 4
bondpaper. Answer the guide questions and nitrogenous bases to their perfect
report it in the class. pair and paste it on the
bondpaper. Answer the guide
questions and report it in the
class.
This are your materials and together with it is
the procedure of the activity. After
performing the activity answer the following
questions.
Alright, are you ready class? Yes Ma’am
Your 3 minutes starts now!
Time’s up!
Let us hear the reporters in eah group.
Time Is Up! The teacher will gather the work of the
pupils and she will check if each group
got the correct answer
D. Analysis
The Teacher will gather the work of the
students and she will check the works every Group 1 are reporting
group.
Let’s begin with Group 1.
Students are clapping
Group 2 are reporting
Job well done group 1.
Clap your hands for them
Let’s proceed to Group 2
Students are clapping
Great Job group 2.
Clap your hands for them
I’m so glad that all of the group cooperates
well and got a very good insights. You all
deserve a big round of applause.
E. Abstraction Our informations ma’am genetic
information
Now, when you hear about the word DNA what
comes to your mind?
Copying or making a copy ma’am
Yes, Very Good!
How about Replication?
Yes, that’s correct! It has something to do on
how we become who we are.
This morning A. Describe DNA Replication
we will explore B. Identify the key players in
DNA Replication.
how
C. Explain the process of DNA
Replication.
DNA replicates.
Before that lets
have
To deepen our understanding be with me this
morning as we discuss about DNA REPLICATION.
At the end of this lesson you are expected to attain
this following objectives:
Everyobody read
In 1953, James Watson and Francis Crick
worked out that DNA is a double helix.
As you can see in this picture class this is
the summary of what happen In DNA Members are forbidden to go outside the
Replication. circle, except when he/she is
passing the message to the next
DNA REPLICATION member
Members are forbidden to go outside the
circle, except when he/she is
DNA Replication is the process of passing the message to the next m
making a copy of the genetic information
contained in DNA. This process is
necessary for cell division and the
transfer of genetic information from one
generation to the next.
So DNA Replication class is simply
producing two identical DNA molecule.
The strand of our DNA molecule class
made of four chemical bases, these are
letters A, T, C and G.
Helicase
In the process of DNA replication, we
have what we call the key players.
When you hear the word enzyme, what
comes in your mind?
Replication Fork
Okay, we need this enzymes in order to
do something to DNA.
What are those key players in DNA
Replication?
So DNA replication you start with a parent
strand and you come up with two
daughters strand which are identical to
each other.
So the First step in DNA Replication is to
separate the two strand.
Primase
Please read
Helicase- (the unzipping enzyme)
an enzyme that unzips/separate the
double helix by breaking the hydrogen DNA Polymerase
bonds between the complementary
bases.
Please read
Replication Fork- very active area where DNA
Replication takes place.
Ligase
It is created when DNA helicase
unwinds the double helix structure of
the DNA.
So the separated strand now, is providing a
Template for creating a new strand of DNA
Let’s procces to another one, kindly read.
Primase (initializer)
Serve as a starting point for DNA
synthesis.
Makes the small piece of RNA Primer.
Let’s procces to another one, kindly read.
DNA Polymerase (the builder)
An enzyme that replicates DNA to build
a new strand
binds with the Primer.
Let’s procces to another one, kindly read.
Ligase- (the gluer)
an enzyme which connects two
strands of DNA together.
To understand more about what really
Happen here, I will show you a video about
The DNA Replication. Helicase
So the DNA splits into two separate strands DNA Polymerase
What causes the split? It is the enzyme helli-
Case. Ligase and
After that we can see that there nitrogenous Primase
Bases attached to each strand. So it’s not
That easy, there should be one who will start
To attach, and that enzyme is called the
Primase also called as the initializer, it
serves
As the starting point of the DNA Replication.
Now the one who build the nitrogenous base
To form a new DNA strand is what we call the
DNA polymerase, that is why is it called the
Builder. And that nitrogenouse bases need to
Be glue or strongly attach or something to
A finishing touch the Enzyme Ligase
So those are the functions of the four
enzymes
Which we call as the Key Players of the DNA
Replication. DIRECTION:
In 3 minutes dramatize the
What are those? process of DNA Replication.
There sould someone stand as the
Yes? key players. Select 1
representative to explain the
process of DNA Replication
Group are portraying
Once the pairing is done what happens is
That, the DNA coils back again and after- Students are clapping
Wards there will be now two copies of original
DNA. Group 2 are portraying
F. Application Students are clapping
Let us have another activity.
With the same group you have. Dramatize
the action taken or the process in DNA
Replication.
Everybody read the Directions
DIRECTION: Students are preparing their ¼ sheet of
In 3 minutes dramatize the process of DNA paper
Replication. There sould someone stand as
the key players. Select 1 representative to Answer Key:
explain the process of DNA Replication
GUANINE
CYTOSINE
Your 3 minutes starts now,
ADENINE
Time’s up! THYMINE
Let’s start with the Group 1
Let’s give 5 claps to G-1 1. Making a copy of the Genetic
information.
How about the G-2 2. Answer may vary
Let’s give 5 claps to G-2
EVALUATION (5 mins)
Kindly get ¼ sheet of paper and answer the
following questions. Write the the letter of
the correct answer.
1-4 Give the 4 nitrogenous bases.
5. It is a process of making copies of DNA
TEST II:
EXPLANATION
1. What is DNA Replication? (2points)
2. Explain how DNA Replication works. (3
points)
ASSIGNMENT
In a short bondapaper draw the
Nerve Cell and label its parts and its
Individual functions.
Alright, so that would be all for today
Class. I hope you learn a lot, and
Don’t forget to pass your assignment
Tomorrow.
Goodbye and thank you class!
Prepared by
BANDIALA, PRIEN MAE A.