SAFETY DATA SHEET according to Regulation (EC) No.
1907/2006
DuPont™ SUVA® 404A Refrigerant
Version 2.4
Revision Date 31.10.2008 Ref. 130000000494
This SDS adheres to the standards and regulatory requirements of Great Britain and may not meet the regulatory
requirements in other countries.
1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING
Product information
™ ®
Product name : DuPont SUVA 404A Refrigerant
Types : ASHRAE Refrigerant number designation: R-404A
Use of the : Refrigerant
Substance/Preparation
Company : Du Pont de Nemours (Nederland) B.V.
Baanhoekweg 22
NL-3313 LA Dordrecht
The Netherlands
Telephone : +31-78-630.1011
Emergency telephone : +44-(0)8456-006.640
E-mail address : sds_support@[Link]
2. HAZARDS IDENTIFICATION
Rapid evaporation of the liquid may cause frostbite.
Vapours are heavier than air and can cause suffocation by reducing oxygen available for breathing.
May cause cardiac arrhythmia.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name CAS-No. EC-No. Classification Concentration [%]
1,1,1-Trifluoroethane 420-46-2 206-996-5 F+; R12 52
Pentafluoroethane 354-33-6 206-557-8 44
1,1,1,2-Tetrafluoroethane 811-97-2 212-377-0 4
For the full text of the R-phrases mentioned in this Section, see Section 16.
4. FIRST AID MEASURES
General advice : Never give anything by mouth to an unconscious person. When symptoms
persist or in all cases of doubt seek medical advice.
Inhalation : Remove from exposure, lie down. Artificial respiration and/or oxygen may be
necessary. Consult a physician.
Skin contact : Take off all contaminated clothing immediately. Flush area with lukewarm water.
Do not use hot water. If frostbite has occurred, call a physician.
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SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006
DuPont™ SUVA® 404A Refrigerant
Version 2.4
Revision Date 31.10.2008 Ref. 130000000494
Eye contact : Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes.
Get medical attention.
Ingestion : Is not considered a potential route of exposure.
Notes to physician
Treatment : Do not give adrenaline or similar drugs.
5. FIRE-FIGHTING MEASURES
Specific hazards during fire : pressure build-up
fighting
Special protective : In the event of fire, wear self-contained breathing apparatus.
equipment for fire-fighters
Further information : Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment. Cool containers / tanks with water spray.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions : Evacuate personnel to safe areas. Ventilate the area. Refer to protective
measures listed in sections 7 and 8.
Environmental precautions : Should not be released into the environment.
Methods for cleaning up : Evaporates.
7. HANDLING AND STORAGE
Handling
Advice on safe handling : Avoid breathing vapours or mist. Avoid contact with skin, eyes and clothing.
Provide sufficient air exchange and/or exhaust in work rooms. For personal
protection see section 8.
Advice on protection : No special protective measures against fire required.
against fire and explosion
Storage
Requirements for storage : Keep container tightly closed in a dry and well-ventilated place. Store in original
areas and containers container. Keep at temperature not exceeding 52°C.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Components CAS-No. Type Control Update Basis
Form of exposure parameters
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SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006
DuPont™ SUVA® 404A Refrigerant
Version 2.4
Revision Date 31.10.2008 Ref. 130000000494
1,1,1,2- 811-97-2 TWA 4 240 mg/m3 2001 EH40 OES
Tetrafluoroethane 1 000 ppm
Engineering measures
Ensure adequate ventilation, especially in confined areas.
Personal protective equipment
Respiratory protection : For rescue and maintenance work in storage tanks use self-contained breathing
apparatus. Vapours are heavier than air and can cause suffocation by reducing
oxygen available for breathing.
Hand protection : Heat insulating gloves
Eye protection : Safety glasses
Hygiene measures : Handle in accordance with good industrial hygiene and safety practice.
9. PHYSICAL AND CHEMICAL PROPERTIES
Form : Liquefied gas,
Colour : colourless,
Odour : slight, ether-like,
pH : neutral
Boiling point/boiling range : -46,7 °C
Flash point : does not flash
Thermal decomposition : 728 °C,
Vapour pressure : 12 340 hPa at 25 °C
Vapour pressure : 23 100 hPa at 50 °C
Density : 1,05 g/cm3 at 25 °C, (as liquid)
10. STABILITY AND REACTIVITY
Conditions to avoid : The product is not flammable in air under ambient conditions of temperature and
pressure. When pressurised with air or oxygen the mixture may become
flammable. Certain mixtures of HCFCs or HFCs with chlorine may become
flammable or reactive under certain conditions.
Materials to avoid : Alkali metals, Alkaline earth metals, Powdered metals, Powdered metal salts
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SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006
DuPont™ SUVA® 404A Refrigerant
Version 2.4
Revision Date 31.10.2008 Ref. 130000000494
Hazardous decomposition : Hydrogen halides, Carbon dioxide (CO2), Carbon monoxide, Fluorocarbons,
products Carbonyl halides
Hazardous reactions : Stable under recommended storage conditions.
11. TOXICOLOGICAL INFORMATION
Acute inhalation toxicity
• 1,1,1-Trifluoroethane : LC50/ 4 h/ rat : > 1 856 mg/l
Anaesthetic effects
/ dog :
Cardiac sensitization
• Pentafluoroethane : LC50/ 4 h/ mouse :
556 329 ppm
• 1,1,1,2-Tetrafluoroethane : LC50/ 4 h/ rat :
358 500 ppm
/ dog :
Cardiac sensitization
Skin irritation : Repeated or prolonged contact with the product may cause removal of natural
fat from the skin resulting in non-allergic contact dermatitis and skin absorption.
Skin irritation
• 1,1,1,2-Tetrafluoroethane : non-irritant
Eye irritation
• 1,1,1,2-Tetrafluoroethane : non-irritant
Sensitisation
• 1,1,1,2-Tetrafluoroethane : Not a skin sensitizer.
Repeated dose toxicity
• Pentafluoroethane : Inhalation rat
No toxicologically significant effects were found.
• 1,1,1,2-Tetrafluoroethane : Inhalation rat
No toxicologically significant effects were found.
Mutagenicity assessment
• 1,1,1-Trifluoroethane : Experiments showed mutagenic effects in cultured bacterial cells., Evidence
suggests this substance does not cause genetic damage in cultured mammalian
cells., Did not show mutagenic effects in animal experiments.
• Pentafluoroethane Did not cause genetic damage in cultured bacterial cells.
• 1,1,1,2- Tests on bacterial or mammalian cell cultures did not show mutagenic effects.,
Tetrafluoroethane Animal testing did not show any mutagenic effects.
Carcinogenicity : Did not show carcinogenic effects in animal experiments.
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SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006
DuPont™ SUVA® 404A Refrigerant
Version 2.4
Revision Date 31.10.2008 Ref. 130000000494
assessment
Carcinogenicity assessment
• 1,1,1-Trifluoroethane : Animal testing did not show any carcinogenic effects.
• 1,1,1,2- Overall weight of evidence indicates that the substance is not carcinogenic., An
Tetrafluoroethane increased incidence of benign tumours was observed in laboratory animals.
Toxicity to reproduction : Did not show mutagenic or teratogenic effects in animal experiments.
assessment
Toxicity to reproduction assessment
• 1,1,1,2- : Animal testing showed no reproductive toxicity.
Tetrafluoroethane
Human experience : Excessive exposures may affect human health, as follows:
Inhalation
Severe shortness of breath, narcosis, Irregular cardiac activity
Further information : Rapid evaporation of the liquid may cause frostbite.
12. ECOLOGICAL INFORMATION
Toxicity to fish
• 1,1,1-Trifluoroethane : LC50 / 96 h/ Oncorhynchus mykiss (rainbow trout) : > 40 mg/l
• 1,1,1,2-Tetrafluoroethane : LC50 / 96 h/ Oncorhynchus mykiss (rainbow trout) : 450 mg/l
Aquatic toxicity
• 1,1,1,2-Tetrafluoroethane : / EC50/ 48 h/ Daphnia magna (Water flea): 980 mg/l
Ozone depletion potential : 0
Global warming potential : 3 784
(GWP)
13. DISPOSAL CONSIDERATIONS
Product : Can be used after re-conditioning.
Contaminated packaging : Empty pressure vessels should be returned to the supplier.
14. TRANSPORT INFORMATION
ADR
Class: 2
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SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006
DuPont™ SUVA® 404A Refrigerant
Version 2.4
Revision Date 31.10.2008 Ref. 130000000494
Classification Code: 2A
HI No:: 20
UN-Number: 3337
Labelling No.: 2.2
Proper shipping name: Refrigerant gas R 404A
IATA_C
Class: 2.2
UN-Number: 3337
Labelling No.: 2.2
Proper shipping name: Refrigerant gas R 404A
IMDG
Class: 2.2
UN-Number: 3337
Labelling No.: 2.2
Proper shipping name: Refrigerant gas R 404A
15. REGULATORY INFORMATION
Labelling according to EC Directives
Special labelling of certain : Safety data sheet available for professional user on request. Contains
preparations fluorinated greenhouse gas covered by the Kyoto Protocol. 1,1,1-
TrifluoroethanePentafluoroethane1,1,1,2-Tetrafluoroethane
The product does not need to be labelled in accordance with EC directives or respective national laws.
16. OTHER INFORMATION
Text of R-phrases mentioned in Section 3
R12 Extremely flammable.
Further information
Before use read DuPont’s safety information., For further information contact the local DuPont office or DuPont’s
®
nominated distributors., DuPont’s registered trademark
Significant change from previous version is denoted with a double bar.
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at
the date of its publication. The information given is designed only as a guidance for safe handling, use, processing,
storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The
above information relates only to the specific material(s) designated herein and may not be valid for such material(s)
used in combination with any other materials or in any process or if the material is altered or processed, unless
specified in the text.
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