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Diabetes Prevention Study Findings

The document presents a literature review matrix summarizing various studies on diabetes prevention interventions, including randomized controlled trials and quasi-experimental designs. Key findings indicate significant reductions in fasting glucose, HbA1c, and body mass index among intervention groups compared to control groups. The studies highlight the effectiveness of automated behavioral interventions and worksite lifestyle changes in reducing diabetes risk factors.

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0% found this document useful (0 votes)
16 views3 pages

Diabetes Prevention Study Findings

The document presents a literature review matrix summarizing various studies on diabetes prevention interventions, including randomized controlled trials and quasi-experimental designs. Key findings indicate significant reductions in fasting glucose, HbA1c, and body mass index among intervention groups compared to control groups. The studies highlight the effectiveness of automated behavioral interventions and worksite lifestyle changes in reducing diabetes risk factors.

Uploaded by

thomvent426
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Table 1

Literature Review Matrix of Articles Used in Critical Appraisal

Study Citation and Level of Purpose Design Sample Measurement Statistical Analysis Key Findings
Evidence tool(s)/Instrument(s)
Block, G., Azar, K.., Romanelli, Evaluate the Randomized 339 randomly Intention-to-treat (ITT) Chi-square – Significant reduction
R., Block, T., Hopkins, D., effectiveness of an control trial assigned individuals analysis categorical variables in fasting glucose in
Carpenter, H., … Block, C. automated with either a fasting intervention group
(2015, October). Diabetes behavioral glucose or HbA1c Alere Cholestech LDX t test – continuous from baseline (mean
prevention and weight loss with intervention for within prediabetes Analyzer variables -0.41mmmol/L, CI -
a fully automated behavioral diabetes prevention range, age 30-69, and 0.44 to -0.12,
intervention by email, web, and BMI >27 Siemens DCA Vantage Linear regression p=<0.001).
mobile phone: A randomized Analyzer
controlled trial among persons Intervention group Significant reduction
with prediabetes. Journal of Heckman correction
(n=163) and control Body Mass Index (BMI) in HbA1c (-0.26%,
Medical Internet Research, group (n=176) 95% CI -0.27 to -
17(10). doi:10.2196/jmir.4897 0.24; P=<0.001).

Level II BMI significantly


reduced 1.05 kg/m2
(95% CI -1.06 to -
1.05; P=<0.001

Diabetes risk reduced

Sepah, S. C., Jiang, L., & 2-year follow-up of Quasi- Met CDC DPRP Wireless scale SPSS Statistics 21.0 Program
Peters, A. (2015, April). Long- diabetes internet experimental criteria as program and SAS 9.3 starter/completers
term outcomes of web-based prevention program single arm starter (n=187); Self-administered reported weight
diabetes prevention program: 2- pilot study on pre- and post- program completer AccuBase A1c test kits Chi-square or Fisher’s between 22-26
year results of a single-arm effectiveness of intervention (n=155) exact test for months (n=131),
longitudinal study. Journal of weight loss and design Online health and categorical variables 52(40%) met or
Medical Internet Research HbA1c DPRP – age >18, demographic questionnaire exceeded CDC
17(4). doi:10.2196/jmir.4052 BMI >/ 24 kg/m2, t test for continuous DPRP 5% weight
light physical activity variables loss
Level III
Provided weight/A1c Lower compliance
at 1 year (n=148) Linear mixed-effects with A1c
measurements. At
Provided weight/A1c Autoregressive-moving 24-28 months 99/187
at 2 years (n=131/99) -average covariance (52.9%). A1c
reduction maintained
Spatial power from 1 to 2 years, no
covariance significant change
(P=0.39)
Weinhold, K., Miller, C., Evaluated efficacy Randomized Employed, Age 18- American Diabetes Pearson x2 or Fisher At 16-week post -
Marrero, D., Nagaraja, H., of worksite controlled trial 65, BMI 25-50 Association risk exact test Intervention group
Focht, B., Gascon, G. (2015, lifestyle with a pretest- kg/m2, prediabetes assessment questionnaire had significantly
November). A randomized interventions on posttest 2-sample t test decrease in weight
controlled trial translating the diabetes and control group Intervention group Physical activity readiness compared to control
diabetes prevention to a behavioral risk with 3-month (n=35); Control questionnaire Spearman correlation (-5.5% [0.6];
university worksite, Ohio, factors follow-up group (n=34) P<0.001); Waist
2012-2014. Preventing Chronic Health-O-Meter circumference,
Disease Public Health Power analysis fasting glucose, and
Professional
Research, Practice, and Policy systolic and diastolic
12(E210). SAS software package blood pressure
doi:10.5888/ped12.150301 Standing Stadiometer JMP version 10 significantly
decreased compared
Level II Alere Cholestech LDX to control (all
System P<0.025);
significantly
Omron healthcare 7-series decrease in total
blood pressure cuff cholesterol (P<0.01)

Block 2005 Food At 3 months post-


Frequency Questionnaire intervention group
(FFQ) remained
significantly
Life-corder Plus decreased for weight,
Accelerometer waist circumference,
and blood pressure
(P<0.05).

Intervention group –
32.4 % met weight
loss goal of 7%
(significantly less
than control;
P=0.003)

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