0 ratings 0% found this document useful (0 votes) 3 views 21 pages The Cell
The document discusses the cell as the basic unit of life, detailing its structure, the emergence of cell theory, and the role of microscopes in studying cells. It explains the differences between eukaryotic and prokaryotic cells, the functions of the plasma membrane, and the composition of the cell wall. Additionally, it covers the structure and function of the nucleus and various cytoplasmic organelles.
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Cell is the smallest entity in which life can exist. It is the least set of chemioy et
that with the help of “life” turns into a stable, living systems with the self replicati? 4
property. a
~~
the
Scanned with CamScannerCELL AS BASIC UNIT OF LIFE
bout which it is believed that
ind it fully, they would be able to unravel the secret
‘scientist will und
th, The discovery of cells and their structure became possible with
ee fe and dea
"of life an nd with the construction of
avid Jansen!in
P| "
icist designed it properly-
e of cork. Later,
in the cells of
‘acellular organization was emphasize
(that living organisms have
3) and Schwann
|in the c |. His observation thus,
jas a structure which
changed the definition
consists of a nucleus
stance enclosed, by a membrane?. Later, it was
1 in animals and plants is similar with only
in addition to the cell membrane.
i | ne described the }
Bo. rounded by a semifluid su
pointed out, that the structure ofa cel
polnjifference. that plant cell has cell-wall
When Robert Hooke first discover
ved the cellas basic unit of life in 1663, he calculated vy
vine -bilion of calls in a “cubic inch” of cork. ne encounters such astonishing
umbers contain frequently in the study of cell biology. A new born human baby
-pontain 2trilion cells; an adult 60 trilion. When you donate blood, you give away 5.4
Srion cells. Each day, infact, a human body sloughs offand replaces 1 percent of its
‘cells or about 600 billion.
4.1.1 Emergence of Cell Theory:
In 1838, Do a a concluded that, despite differences
in the structure 0! issues, plants were made of cells. In 1839, a German
1, published a comprehensive report on the cellular basis of
rimals, Both of them proposed the cell theory which state that: *
are composed of one or more cells.
| and functional unit of life.
? °
found in each-cell,
in animal cells single Golg! apparatus is cell, in p
cell, epmayis more. Golgi apparatus are especially prominent in glandular cgi
The products of E.R. aré modified and stored, and then sent to other destination,
‘They perform the function of collection, packaging and distribution, {
addition to its finishing work, the Golgi apparatus manufacture certal
macromolecules by itself. Many’ polysaccharides secreted by cells, like cell-wall aryl
cell plate material in plant cell are Golgi products. .
Plasma
(iv) Lysosomes: _ ,_..
These are spherical
bodies, a few micrometer in |
diameter, surrounded by @ engulfing
single membrane, originated ow
by Golgi apparatus and Lysosome ‘i
containing digestive enzymes. i
They occur only in the
cytoplasm ofanimal cells, and
function in the digestion of
material taken into the cell by
, as bacteria are
ingested by white blood
corpuscles. Normally they
function as destroyers of
foreign particles and worn out
cellular components. When the
membrane of lysosomes is
memberane / 44 Digestion City , >
/ @ Autophagy
(lysosome
chemical breakd :
i rece So aaa Fig. 4.12 Formation and function af lysosomes
cause a cell to destroy itselfby digesting its own, eins, lysosomes havebeenrefe
as “suicide sacs” Bea arossaa et eee 7
Disturbance in lysosome function has ‘puman heall
1965 [Link] of Belgium explained how the Crete
lysosomal enzyme, oc-glucosidase, could lead to the storage of undigested é!
accumulate in lysosome causing swelling of the organelles and irreversible d
to the cells and tissues. Diseases of this type, characterized by the deficient
lysosomal enzyme and He corresponding accumulation of ‘undergraded sul
are calle: e disorder, over.30 disorders have been reported,
ey
Scanned with CamScannerOLOGY
om some are described in the following table. <=
fable 4.1 Sphingolipid/ storage diseases ‘ ~~
Disease | Consequences
: ’ | = Mental retardation, blindness, death by age 3.
- Liver and spleen enlargement, erosion of long
bones, mental retardation in infantile form only.
_ Krabbe’s disease ~ Loss of myelin, mental retardation, death by age 2.
Plastids: .
‘They are especial protoyilAsmic double membrant bound organelles which
ction as chemical synthesizers and storage bodies. Plastids occur in greatest
umberin cells of plants and in the primitive single celled organisms, the Protoctists.
‘There are three types of plastids e.g. Chloroplast, Chromoplast and Leucoplast.
i) Chloroplast (Gr: Chloro=green, Plast=living): The most common
of plastid is chloroplast containing chlorophyll which gives plant their green
Jour and is of great importance in the manufactute of food by the process of —
thesis.
Chloroplasts contain a substantial amount of DNA and are capable of
synthesis of some other new structural components. It has its own
(v)
ii): | Chromoplast (Gr: Chroma=colour, Plast=living): They have pigments
¢xanthophyll, and carotene. The chromoplasts are responsible for the various
olour combinations found in flowers, fruits and other coloured parts except green.
iif) Leucoplast (Gr: Leuco=white): These are/¢olourless plastids which
levelopin the absence of sunlight and are thus commonly found inall under-ground
arts of the plants. They_store the food material_as_carbohydrates, lipids_and
Proplastids: Proplastids are immature, colourless plastids occuring in cells
f meristematic tissues. They consist of double membrane enclosing granular
troma. They multiply by division. In mature cells proplastids develop into chloroplast
r chromoplast or leucoplast. .
Chloroplasts as energy converting Organelles:;
A typical plant cell has especial type of energy converting organelles,
chloroplasts, They have an ability to convert solar energy (light energy) me k
chemical/food energy by the process of photosynthesis, th called site of
hotosynthesis. Chloroplasts belong toa group of double-n ‘bound =
°y Contain chlorophyll and its associated proteins. _ ‘
Scanned with CamScannerOne lamella
Inter-granal lamella,
‘Double membrane bounding chloroplast
Fig. 4.13 The site of photosynthesis in a plant
During photosynthesis, chlorophyll captures the energy of sunlight aii
transfers it to other molecules in the thylakoid membranes. These moleculesia
turn transfer the energy to ATP and other energy-carrier molecules. The energ
carriers diffuse into stroma, where their energy is used to derive the synthest
of sugar from carbon dioxide. Due to this movement of energy from one form’
another, chloroplast is an energy converting organelle.
(vi) Peroxisome:
Peroxisome are
bounded microbodies that contain enzymes’ ’
for transferring hydrogen atom to oxygen;;) 1
forming hydrogen peroxide (H,O,), a toxic | Sag
molecule that is immediately broken down ™
towater by the enzyme catalase. Peroxisome.
are abundant in cells that hre metabolizing
alcohol, Peroxisome are to help in ag
detoxification of alcohol. They are found in y Poronsomes
plants and animals. “Wig. 4.14 wnciniata
Scanned with CamScannerPeroxisomes contain enzymes that breakdown damaging cor
peroxisomes ithin liver and kidney cells breakdown and detoxify full
of the alcohol a person drink.
Glyoxysome:. .
another type of microbodies found in plants only which are also consider
specialized peroxisomes called glyoxysomes.
'g, Each glyoxysome hasa single layered bounding membrane enclosing a
ar stroma. Glyoxysome contain enzymes that initiate the conversion of fatty_
Cytoskeleton: ‘The cytosol is organised into a three dimensional network of
brous proteins called cytoskeleton. It plays fundamental roles in mitosis, meiosis,
esis, cell-wall deposition, the maintenance ofcell-shapeand cell differentiation.
‘There are three types of cytoskeleton elements found in cells.
Microfilaments are solid strand of: ‘about 7 nmin diameter and several
qitiséle cells. They are consists of two actin chain that
tertwine in a helical fashion, some microfilaments also contain sin
ith actin. They perform function of muscle contraction, changes in cell sha]
(cluding division of cytoplasmic in dividing animal cells, cytoplasmic streaming
ovement of pseudopodia. a = 7
1) Intermediate filaments are solid strands of to 11 nmin diameter,
D to 100 um in length. They are intermediate in between microtubules and
crofilaments. They are made up of atleast five different types of protein. form rope
polymer of fibrous protein. Unlike the other two types of cytoskeleton elements,
itermediate filaments do not assemble and disassemble._Therefore, they are
pportant in maintaining the shape of cell, attachment of muscle cells, support of
cell processes (axon). ‘
¢) Microtubules are hollow tubes with an outel
more than 50 umin length. They are composed of prot
bule consists of hundreds of thousands of tubulin sul
columns called proto filaments, they are respon
omosomes during cell division, movement of o1
pvement of cilia and flagella.
a)
m in length especially 1
Scanned with CamScanner70 i THE I
Contriolo
Intermediate
filament
Microtubule
Plasma membrane
filament
bundle vament
Microtubule Intermediate filament jotamavet
Protofiament
— =
| Fig. 4.18" Thiree dimensional structure of cell. Showing distribution of
cytoskeleton and structure of micro tubules and micro fuament
. . SY .
(iit) Ribosbines!=> Patadatiscovece . coma
‘These are so named because they contain high concentrati
acid (RNA). small structures are sites of protein synthesis in all cell
Sroulonan
Scanned with CamScanneroL0GY I
okaryotic as well as cukaryotic cells. Ribosomes a a
fhe cytoplasm in prokaryotic cells. But in cuka tle sate nee, oe
well as attached to endoplasmic reticulum. Biercround free
¢ different kinds of proteins. There are mi
si ee a _
us the:
me y produce the protein needed by the cell.
subunit GOS ©
S— Ribosome ‘
Transport
\ Vesicle formation vesicie
Receptor protein : ‘
Fig. 4.16 Structure of ribosomes and attachment of ribosome with ER.
Eachribosome consists of two unequal subunits. ‘Thelarger subunit is dome-
shaped and cap on the flat surface of larger subunit. Some
dhere themselves to endoplasmic reticulum ty the larger subunits.
ibosomes at
Although ribosomes are among the smallest organelles, they are among the
most vital cellular components. Recent investigations reveal that the ribosomes are
ufactured in the nucleolt ferred to the cytoplasm.
hrough nucleopores.
rection 0!
tis from where they are trans
. Within
¢ centrosome of an animal cell is a pair
of centrioles. Centrioles are short; barrel
+ shaped structures of microtubules, lying
perpendicular to one another. Each
entriole is composed of nine se
triplet microtubules arranged in a ring.
hen a cell divides, the centrioles
Teplicate, move to opposite side of the cell
and thread like fibres begin to radiate
from centrioles in all directions called(x) Vacuoles: soy, 1 :
Genrally vacuoles (except food vacuole) are ‘nonprotoplasthic liquid 4
cavities in the cytoplasm and are surrounded by a meni paimBeatiee ta. i
The tonoplast is selectively permeable, it allows certain substances to enter ij
vacuole. In animal cells they are temporarily formed at the time of their need. rm
are conspicuous organelles of plant cells. They are more Prominent in maj They
whereas less prominent in immature cells. The vacuoles in plant cells are i el
cell sap and act as store house, which often plays role in Plant defen “a
necessary for plant cell enlargement. In animal cells, lysosomes are i Which}
lytic enzymes, including proteases, ribonucleases and glycosidases, aS =
parapet act as lysosome as they contain hydrolytic enzymes and Prt
° tonoplast lose its differential permeability and its
Fig. 4.18 Plant cell vacuole.
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