S\'i\1B10S1S INTERNATION1-\L (DEEl\lED lJNl\'EllSll' Y)

( E s t ~ under Sec:tion 3 of the UGC Ad. 195t! )

R ~ t e d by NMC •·ith 'A♦♦• Grtlde 1'--rded [Link]--~-?....-...1__.by;.,;V....
O....,C,.,_.-,--,.--,---,.-, .,

I seat No.f 5 lj (,_ I, f,. I~ I

Institute: (0413)SYAIBIOSIS MEDICAL COLLEGE FOR WOMEN, PUNE

Programme: (041321) BACHELOR OF MEDICtNE ANO BACHELOR OF SURGERY

Batch: 2023-29
Phase: I
Course: Human Anatomy Paper I
Course Code: 0413210101

Date: 09,'08/202.$ Maximum Marks: 100

Day: Friday Time: 10:00 -13:00

NOTE : DO NOT WRITE ANYTHING ON THE QUESTION PAPER

Instructions: • •·• • ••• ••

l) Use blue/black ballpoint pen only.
2) Do not write anything on the blank portion of the question paper. If \\Titten anything, such type
of act \\ill be considered as an attempt to resort to unfair means.
3) All questions are compulsory.
4) The number to the right indicatet full marks.
5) Draw diagrams wherever necessary.
6) Distribution of syllabus in Question Paper is only meant to cover entire syllabus within the . t

stipulated frame.
7) The Question paper P.1ttcm is a mere guideline. Questions can be asked from any paper's
..-_...:.::==-~_:11abus into :my questiott'"paper; Students cannot claim that the Question is out ofsyffnhus. As I
it is only for the placement sake, the distribution has been done.
8) Use separate answer books for Section B and C . (~
I Section "B" (40 marks) ~}
Q. 2 Short answer questions (Any six out of seven) (6 x 5 Marks= 30)
~ ?lassify the fibrous joints with an example of each. 3
~ - An 18-year-old student was doing part-time work delivering pizzas on· his
• motorcycle. His boss insisted on quick delivery, so the student tended to weave in
and out of traffic whenever there was a holdup. On one occasion, he misjudged the.
gap between two vehicles, and a car bumper violently struck the outer surface of
his left knee. Examination in the emergency department showed he had extensive
paralysis of the muscles of the anterior and lateral compartments of the left leg. As
a result, the patient was unable to dorsiflex the ankle joint and evert the foot In
addition, he had diminished sensation down the anterior and lateral sides of the
leg and tops of the foot and toes, including the medial side of the big toe. A series
of radiographs of the knee region showed no evidence of bone fractures.
i) Why patient was unable to dorsiflex and evert the foot?
ii) Name the muscles supplied by involved nerve in this case? J
iii)Name the foot deformity in this case? (1 +3+ 1 marks)
~ a w well labelJed diagrams depicting microanatomy of serous salivary gland and
mucous salivary gland '?
Page 1 of02
 4cad aver as first teache r I
maxim us muscle
e)/De scribe the attach ments , nerve supply and action s of gluteu s
_jf Super ior media stinum r
) .~
/ Write in detail about micros copic struct ure of Supra renal Gland

Q.3 Long Answ er Quest ions (Any one out of two) (1 x 10 Mark s= 10)
( 4+4+2)
a) Descri be Right atrium under following headin gs:
i. Intern al featur es of Right atrium & openin gs in right atrium
ii. Devel opmen t of Right atrium
iii. Applie d anato my
yesc ribe the hip joint under the following headin gs:
/Ty pe (1)
X, Articu lar surfac es and ligame nts (3)
/4 Relations (diagr am only) (2)
.A Move ments and muscl es produ cing tllPm ( 4)

Section "C" (40 marks )

~ S~rt answ er quest ions (Any six out of seven ) (6 x 5 Mark s= 30)
j y Descr ibe the suppo rts of uterus
(3+2)
I ~esc ribe the develo pment of kidney and its anoma lies
the blood vessel s involv ed
I

~ u l a t e the sites of porto- system ic anasto moses specif ying

I KOe scrib e micro scopic struct ure of Pancre as

l
,•.
tf
/
e) ,_,Yerineal pouch es
~ Devel opmen t of inferio r vena cava
Rectus sheath

s= 10)
[Link] Answ er Quest ions (Any one out of two) (1 x 10 Mark
gs: ( 4 +4 +2 )
a)/ Describe stoma ch under the following headin
✓ / Gross featur es
~ Blood supply
..ii( Applied anatom y
(5+3+ 2)
b) Describe anatom y of urinar y bladde r under the following headin gs:
i. Gross featur es includ ing Interio r
ii. Nerve supply
iii. Applied anatom y

[Link] 2 of 02
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• SYMBIOSIS IN~~~,~-~!.!.?.~~~'"~?.~.~-~~D UNIVERSITY)

- . Re-accredited by NAAC with 'A++' Grade I Awarded Category -1 by UGC
r"-[se...._at__._No-y-.15-.-lq_l_l-...--16--l,_--.-1o--,1
Institute: (0413)SYMBIOSIS MEDICAL COLLEGE FOR WOMEN, PUNE

Programme: (041321) BACHELOR OF MEDICINE AND BACHELOR OF SURGERY

Batch: 2023-29
Phase: I
Course: Human Anatomy Paper II
Course Code: 0413210101

Date: 10/08/2024 Maximum Marks: 100

Day: Saturday Time: 10:00 -13:00

NOTE : DO NOT WRITE ANYTHING ON THE QUESTION PAPER

Instructions:
1) Use blue/black ballpoint pen only.
2) Do not write anything on the blank portion of the question paper. If written anything, such type
of act will be considered as an attempt to resort to unfair means. ·-"-- ,
3) All questions are compulsory. • _;
4) The number to the right indicates full marks. ,"-.. ,, ·--.. .,
5) Draw diagrams wherever necessary. '· __
6) Distribution of syllabus in Question Paper is only meant to cover entire syllabus within the
stipulated frame. • •',,.~
1) Tb • deline. Questions can be asked from any paper's '\..
_ Is cannot claim that the Question is out of syllabus. As ', "
it is only for the placement sake, the distribution has been done.
8) Use separate answer books for Section B and C ~

Section "B" (40 marks) \ : /

, '

Q. 2 Short answer questions (Any six out of seven) (61 X s Marks= 30)
. /Histology of pituitary gland P~
b) _}permatogenesis
ff Anastomosis around elbow joint ; •~
d} Aneonate was brought to th~ pediatric OPD with deformity of ~e right upper limb. , ._ >·
/ Mother gave history suggestive of prolonged and obstructed labor. On examination, -, -,
diagnosis ofErb's palsy was made. -~ ··-
L What is Erb's palsy? 1 _ (1) -,
,%.' Which is Erb's -point? 1 ' (1)
y
List the muscles responsible for each component of that deformity. (3)
~raw & label T.S. of mid brain at superior colllculus '?, .
$ Development of Neu~al crest cells and their derivatives 0
r11 /f>evelopment of tongue with congenital anomalies
.,::y - 3

Pagel of02
.'
j

•..
~

j Y a)
Long Answer Q~esti ons (Any one out of two) ( tx 1 O Marks =
1O)
Describe the Poster ior triangle of neck under the following headings:
i. Boundaries ( 4)
ii. Subdivisions & conten ts ( 4)
iii. Applied anatom y (2)
~esc ribe the Shoul der joint under the following headings:
y
Type and Articular surfaces (2)
y.
Relations 7; (2)
~ Movements and muscles produ cing them
(3)
V
Clinical anatom y (3)

Section "C'; {40 marks) ~~

Q. 4 S)ort answer questions (Any six out of seven) (6 x 5 [Link] = 30)
$ .Jmsa cervicalis (}J
J>(' Boundaries &contents of middle ear 9 '
y yawn 's Syndrome ~
~ A 20 year old boy was broug ht to hospital with a head injury. Next day he
developed
blac}sish discolour aro~nd his Right eye or black eye.
cif,.Explain the anatomical basis of this condition (1) 1b
~ Name the layers of scalp (4)
~Lateral wall-of nose: -conchae and meatuses :;i,, S
y f) Auditory tube
Enumerate derivatives of pharyngeal pouchr. s
Q.5 J,d'ngAnswer Questions (Any one out of two) (1 x 10Marks = 10).
~ A 60 year old lady came with a midline swelling in the
neck. On examination, the
swelling was moving with d~glutition. On this clinical basis, answe r the
following
questions:
i./flam e the struct ure involved
¥Des cribe its gross anatomy
(1)
(2)
1
!il/Y, rite its relatio ns • (4)
Y, Describe its microscopic structure (3)
b) Describe supero lateral surface o( cerebrum under the following headin
gs:
i. Suki & Gyri (4)
ii. Functional areas (3)
iii. Applied anatom y (3)

Page 2 of02

I
 SYMBIOSIS [Link] (DEEMED UNIVERSITY)
(Eatab-:lshed under Section 3 of the UGC Act, 1956)
Re-accredited by NAAC with 'A++' Grade I Awarded Category- I by UGC
~I 9--\2--\,-,l-........,-0\
Se"-atN-,o.(~~-,

Institute: (Q413)SYMBIOSIS MEDICAL COLLEGE FOR WOMEN, PUNE

Programme: (041321) BACHELOR OF MEDICINE AND BACHELOR OF SURGERY

Batch: 2023-29
Phase:
Course: Physiology Paper I I

Course Code: 0413210102

Date: 12/08/2024 Hl©~ Maximum Marks: 100 ~-

Day: Monday
t, l-1;-vv)t Time: 10:00 • 13:00
Ff,Ji~J rwv✓t
NOTE: DO NOT WRITE ANYTHING ON THE QUESTION PAPER
,I
Instructions:
1) Use blue/black ballpoint pen only.
2) Do not write anything on the blank portion of the question paper. If written anything, such type
of a~t will be considered as an attempt to resort to unfair means.
3) All questions are compulsory.
4) The number to the right indicates full marks.
5) Draw diagrams wherever necessary.
6) Distribution of syllabus in Question Paper is only meant to cover entire syJJabus within the
1
stipulated frame. ' -
1) ~~ • • ............- ..e guideline. Questions can be asked from any paper's.''~-:
.~--·· •~ ~--"-syitaous mo n que ton paper. Students cannot claim that the Question is out of syllabus. A~
it is only for the placement sake, the distribution has been done.
8) Use separate answer books for Section B and C

Section "B" (40 marks) A

Q. 2 JKort answer questions (Any six out of seven) (6 x 5 Marks= 30)

.;tJ
Enumerate short term Blood Pressure regulatory mechanism. Explain Baro receptor
reflex in detail.
~er:~ & classify shock. What is the physiological basis of management of hY,Po~:lemic

~ l a i n ionic basis of spike potential with well-labeled diagram. ~

f hnumerate & Describe professional qualities & roles of physician in patient care.
e) Write intrinsic pathway of blood clotting with its applied aspect.
n ./hescribe the events of the left ventric~lar systole wj;th_ pressure & volume changes in
;y ;, tail. w/.N brvNjj(li., ~

A 60 year old man is admitted to the hospital'With the complaints of weakness, fatigue
d dizziness. The doctor diagnosed the condition as Hypokalemia and he is started on
supplemental potassium, with improvement in symptoms.
1) What is the normal K• distribution between ICF &ECF? (1)
2) Mention the factors that alter the distribution of K• in ECF & ICF. (2)
3) Why the person is showing the muscle weakness? (2)
Page 1 of02
 -- -- -- -- - - -
A' T' ,..-
SY M BI O SI S IN TE RN ·v ER Sl TY )
1 JN
IV ER SI TY )
__ . r , , n

, 1

' rk s= 10 }
sw er Qu es tio ns (A ny one out of tw o} (1 x 10 Ma
~ ~ n g An (3)
cla ssi fy dif fer ent typ es of im mu nit y.
J .~- De fin e an d (4)
Na me the an tib od ies & giv e the ir £unctions.
.~~- (3)
111 W ha t is ac qu ire d im mu ne deficiency sy
ndrome?
•
(3)
tpu t, St r~ ol um e, ~a rd ia c index.
/ . ' . · D~fine C ~ Ou ( 4J
s reg ula tin g ca rdi ac ou tp ut
uv .b1 sc us s factor rdiac ou 9> 9t (3)
on Fic k's me thod of me asu rem en t of ca
_3Y'A dd a no te ,...,,., r/J.j;. 1.,,\,\J / '/ r
·
Section "C" (40 marks)
ny six ou t of se ve n) r (6 x 5 Marks= 30 )
Q. 4 Short an sw er qu es tio ns (A ~m lab or an d
ma n pre sen ted to the ho sp ita l in pr ete
After th e
f A 24 -ye ar -ol d p~eg na nt wo
pr em atu re inf an t at on ly 27 we ek s ge sta tio n.
ygen
su bs eq ue ntl y de liv ere d a bs eq ue ntl y sh ow ed sig ns of hypoxia de sp ite ox
bu t it su e an d giv en
delivery, the inf an t cried, dia tel y wa s int ub ate d by en do tra ch ea l tub
ba by im me wa s
supJ?lementation. The
ch ea J tub e. Th e ba by 's hy po xia res olv ed , an d he
tra
su rfa cta nt do wn the endo siv e ca re un it for fu rth er sta bil iza tio
n.
ne on ata l int en (3 )
tra ns fer red to the in the lun g?
su rfa cta nt (1 )
i) W ha t is the rol e of y res ist an ce?
e of air wa y res ist an ce ? (1 )
ii) Where is the ma jor sit ras ym pa thetic sy ste m aff ec t air wa
lat ion of the pa
.,/'1ii) How does sti mu os ph ere .
~ ye sc rib e tra ns po
rt of CO2 from tissues to atm tiz ati on . (1 +4 )
on ? Ex pla in the ch an ge s oc cu rri ng du rin g ac cli ma
sY What is acclimatizati (2 +3 )
ctions of Pa nc rea tic jui ce ?
~ What is the composition & fun pty ing . •
e & dis cu ss the factors regulating ga str ic em
eJ ?u m er at
ine. Ad d a no te on de fec ati
on reflex.
of lar ge int est
y ?x pla in the mo ve me
d
nts
dia gra m of EC ? in Lead II. Wr ite in sh or t th
e ca us es, no rm al
~ r a w a well- lab ele
h wa ve in ECG.
du rat ion an d voltage of eac
= 10 )
sw er Qu es tio ns (A ny on e out of two) (1 x 10Marks
Q.5 Long An (2)
an d lab el res pir ato ry me mbrane.
a //D ra w (3)
fac tor s aff ec tin g dif fusion of gases ac ro ss it.
ii /fa pl ai n (SJ
V /P rat io. W h .~ r-/JJl'J./ :
✓ ,Add a no te on
(6)
in the co un ter -cu rre nt multiplier me ch an ism . I
i. Expla (1)
b)
•• W ha t is its pu
11.
••• Ad d a no te on
111.
rp
Di
os e?
ab ete s Ins ipi du s.
(3)
I
f

Page 2 of 02
 _ _ _ _ ..,________ _______, ___________
SYMBIO SIS INTERN ATIONA L (DEEME D UNIVERSIT_Y)
• (Established under Section 3 of the UGC Act, 1956)
Re-accredited by NAAC with 'A++' Grade I Awarded Category - I by UGC
_ ,,.__lse-atN--.o.,---
0 -, q--,.2---,-.-,,-,_,___,,0I
Institute: (<'413) SYMBIOSIS MEDICAL COLLEGE FOR WOMEN, PUNE.

Programme: (041321) BACHELOR OF MEDICINE AND BACHELOR OF SURGERY

Batch: 2023-29
Phase: I
Course: Physiology Paper II
Course Code: 0413210102

Date: 13/08/2024 MC,.~ J. , Maximum Marks: 100

Day: Tuesday • ~~ F''[Link] Time: 10:00 -13:00

rv:or;J,1;,~. D t,&.-+i •
NOTE: DO NOT WRITE AN't-THING ON THE QUESTION PAPER

Instructions:
1) Use blue/black ballpoint pen only. ...
2) Do not write anything on the blank portion of the question paper. If written anything, such type
of act will be considered as an attempt to resort to unfair means. '
3) All questions are compulsory. ..,
4) The number to the right indicates full marks. . "',
5) Draw diagrams wherever necessary. ',,
..
6) Distribution of syllabus in Question Paper is only meant to cover entire syJJabus within the_ ..•
stipulated frame.
._. __ . ,J) ~rtie.~ ~~p~-~ m is a_ ~ere guideline. QuesJions can be asked from any pap~r's
syllabus into any question paper. Students cannot claim that the Question is out of syllabus. As
it is only for the placement sake, the distribution has been done.
8) Use separate answer books for Section B and C

Section "B" (40 marks)

; .
Q. 2 Short answer questions (Any six out of seven) (6 x 5 Marks= 30)
,/A 45-year-old female came to the OPD with complaints of weight gain, hirsutism, and
-:i

7 ;menorrhea. On clinical examination, the doctor noticed purple striae on her abdomen.
Her blood pressure was 150/90 mm Hg.
Atate the hormonal abnormality and causes of this condition
jVMention the causes of any two symptoms/signs mentioned in the above case scenario.
•• ~ Describe the physiological basis of its treatment. . (2+2+1)-
)3"/ Write a short note on impedance matching in middle ear
yDescri be the role of sarcotubular system in the excitation-contraction coupling of s~eletal
v /ffiUScle
ft Describe the bodily responses on exposure to hot environment. Add a note on heat stroke
•. (3+2)
fi Describe Milk ejection reflex in detail • '

~ ~rite the differences between Decerebrate and Decorticate rigidity

JY vtscuss the functions of hypothalamus in detail

Page 1 of 02
r •

✓Long Answer Questlon_s (Any one out of two) (1 x 10 Marks= 10)

a) 1. Descfibe the origin, course, and termination of corticospinal tracts (4)
ii. Write functions of cortlcosplnal tracts. (2)
iii. Describe the clinical features of corticospinal tract lesion at the level of (4)
1) Internal capsule on Right side
/ 2) spinal cord segment T 10 level on Right half
-91" /Describe the ovarian changes during menstrual cycle and its hormonal regulation (6)
j0' Describe the indicators of ovulation
y Add a note on the mechanism of action of oral contraceptive pills
(Z)
(2)

Section "C" (40 marks)

Q. 4 S~rt answer questions (Any six out of seven) (6 x 5 Marks= 30)
,ef'., Compare &contrast isometric and isotonic contraction
__,,.ijf ~eo/ibe the actions and regulation of secretion of aldosterone
/4;;aw a well-labelled diagram of fast pain pathway (2)
•• Describe referred pain (3)
...-cf) ~ite the differences between slow twitch and fast twitch muscle fibres
~Add a short note on physiological functions of testosterone
f) Write a short note on neurohormones and neurochemicals involved in the sleep-
wakefulness cycle
i:,~ /13 old Ramesh got failed in the driving licence examination; because he was not able to
I
I / differeptiate the road traffic signal colours.
A
-v."_,))escribe the condition he is suffering form (2)
I
~
y What are the different theories of this clinical condition (3)

Q.5 Long Answer Questions (Any one out of two) (1 x 10 Marks = 10)
a) Enumerate the different phases of an action potential in a neuron with a neat
labelled diagram. Describe the ionic basis of various phases of the action potential.
What is the absolute refractory period? Mention the ionic basis of the absolute
refractory period in neurons. (4+3+ 1+Zt
~ A SO-year-old man came to the outpatient department complaining of difficulty in
maintaining a balance since 15 days. On examination, it was seen that he had an
intej)tion tremor, hypotonia, and pendular knee jerk.
_/4'" What is the provisional diagnosis? (2)
i~umerate the connections and functions of the structure of the central
nervous system that is affected in the patient. (6)
~ Add a note on motor and sensory ataxia. (2).

Page 2 of 02
 SYMBIOSIS INTERNATIO NAL (DEEMED UNIV-ERSITY)
(Established under Section 3 of lhe UGC Act 1956)
Re-accredited by NAAC with 'A++' Grade I Awarded ca'te O -1
~ " " - - -. . . . .~ i - - - . . - - - - - -

Institute: (0413)SYMBIOSIS MEDICAL COLLEGE FOR WOMEN; PUNE

Programme: (041321) BACHELOR OF MEDICINE AND BACHELOR OF SURGERY

Batch: 2023-29
Phase: I
Course: Biochemistry Paper I
Course Code: 0413210103

Date: 16/08/2024 Maximum Marks: 100

J

Day: Friday Time: 10:00 - 13:00

NOTE : DO NOT WRITE ANYTHING ON THE QUESTION PAPER

....... ....
Instructions: ' -,-
1) Use blue/black ballpoint pen only.
2) Do QQt write anything on the blank portion of the question paper. If written anything, such type
'
of act will be considered as an attempt to resort to unfair means. ;
3) All questions are compulsory.
4) The number to the right indicates full marks.
5) Draw diagrams wherever necessary. "
6) Distribution of syllabus in Question Paper is only meant to cover entire syllabus within the ..
stipulated frame. ',
7) The Question paper pattern is a mere guideline. Questions can be asked from any paper's
syllabus into any question paper. Students cannot claim that the Question is out of sy\\abus:A.s
it is only for the placement sake, the distribution has been done.
8) Use separate answer books for Section B and C

Section "B" (40 marks)

Q. 2 ;,Port answer questions (Any six out of seven) (6 x 5 Marks= 30)
A §icosanoids; Classification & clinical uses (2+3)
/oescribe common barriers of effective communication. (5)
c) Unconjugated Hyperbilirubinemia (5)
A Immunoglobulins (5)
' / Isoenzymes and their clinical significance (2+3)

.,Y CSF in health and disease (2.5 +2.5)

rytochrome P450 (5)

Q.3 Long Answer Questions (Any one out of two) (1 x 10 Marks= 10)
a) Discuss lipoproteins under;
i. Classification of Lipoproteins. (3)
ii. Describe metabolism of two lipoproteins in detail (4)
...
Ill, Add a note on Hyperlipoprotein emia. (3)

Page 1 of02
 ✓oi~ss Enzymes
~'./ Definit~on & Mechanism of action (1+2)
~ J=lassification (2)
J" Factors affecting Enzyme activity (5)

Section "C" (40 marks)

Q. 4 Short answer questions (Any six out of seven) (6 x 5 Marks= 30)

4linic al significance of Dietary fibre. Assessment of obesicy, (3+ 2)

~ Glycogenolysis & its regulation. (4+1)
hDiagn _ostic and therapeutic uses of enzymes (2.5 +2.5)
_,.AlJ Protein Energy Malnutrition (PEM) (2.5 +2.5)
~Elect ron transport chain and its inhibitors . (4+1)
t) Describe the biochemical basis underlying fatty liver. Add a note on lipotropic factors.
y/Four _ Tumor markers and their clinical significance (3+2)

Q.5 Long Answer Questions (Any one out of two) (1 x 10 Marks= 10)
i f Dessµbe glucose homeostasis under the following heads:
✓- K )legulation by hormones and various organs. (4)
✓.'))iagnostic criteria for Diabetes Mellitus. ADA criteria (3)
jiV" Enumerate chronic complications of Diabetes mellitus and their underlying
biochemical mechanisms. - - - (3J-- -~

b) Explain the amphibolic nature of TCA cycle. Describe the reactions involved in the
efflux of TCA cycle intermediates. Describe the anapleurotic reactions. Add a note
on inhibitors ofTCA cycle. (2+3+3+2)

Pagt..' 2 or 02
 sv~1.nros1s INTERNATIONAL (DEEMED UNIVERSITY)
(Batabllohed u11d11r 8eollot1 3 of the UCJO Aot, 1g68)
Ra•l\OCr~dltod by NAAO with 'AH' Orndo I Awarded Oatof'-gc,....,ry.._-_I_..,by1U_010 --ir--Y--r- -""T--.
[seat [Link] b }.2 Ib j,_ j oj
lmHltuto: (0413)SYMBIOSIS MEDICAL COLLEGE FOR WOMEN, PUNE

Programmo: (041321) BACHELOR OF MEDICINE AND BACHELOR OF SURGERY

Bntoh: 2023-29
Plu1so:
Course: Bloch8mlstry Popor II
Course Codo: 0413210103
Maximum Marks: 100
Dato: 17/08/2024
Time: 10:00 - 13:00
Day: Saturday
NOTE : DO NOT WRITE ANYTHING ON THE QUESTION PAPER

Instructions:
1) Use blue/black ballpoint pen only.
2) Do 11ot write anything on the blank portion of the question paper. If written anything, such type
of act will be considered as an attempt to resort to unfair means.
3) All questions are compulsory.
4) The number to the right indicates full marks.
5) Draw diagrams wherever necessary.
6) Distribution of syllabus in Question Paper is only meant to cover entire syllabus within the
stipulnted frame.
,
l

7) The Question paper pattern is a mere guideline. Questions can be asked from any paper's
syllabus into any question paper. Students cannot claim that the Question is out of syllabus. As
it is only for the placement sake, the distribution has been done.
8) Use separnte answer books for Section B and C
~ n "B" (40 marks)

~ r t answer questions (Any six out of seven) (6 x 5 Marks = 30)

~ Role of enzyme markers in assessing liver disorders.
b) What is gene therapy? Name the vectors used for gene therapy and add a note on
clinical application of gene therapy. (2+2+ 1)
/ Salvage pathway in purine metabolism. (5)
.Y,An eight years old boy was brought by his parents with complaint of difficulty in
• objects in dark for few months.
at is the probable diagnosis? (1)
hat can be other manifestations in the eyes of the patients with this disease
cond'tion? (2)
i" Describe the mechanism of dark adaptation? (2)
A ,)}escribe folate trap and its significance.
1~~n absorption RDA source functions (2+ 1+2)
JY Role of communication in Doctor-P atient relationship

Page 1 of 02
Y . )'fn g Answ,er Questions (Any one out of
two) (1x 1oMarks = 10)
base regulation. Add a note on acid-
.,Y Describe the role of hemoglobin as buffer in acid- (4+6)
base imbalances
(4)
b) i. Describe hemoglobin metabolism
(4)
ii. Describe disorder associated with Heme catabolism
in a case of hemoglobin
iii. Various laboratory tests/investigations to be done (2)
catabolism

_ / L " C " (40 marks)

(6 x 5 Marks= 30)
9/4 Short answer questions (Any six out of seven)
nts with history of with swelling
a) A two year old male child is brought by his pare
y investigations show:
over face and lower limbs for past 1 month. Laborator
• Serum Total Protein: 4.5 g/dL
'
• Serum Albumin: 1.5 g/dL
\

• Serum Total cholesterol: 400 mg/dL

• 24 hr urine protein: 4.2 g/day (2)
i. What is the likely diagnosis? bora tory
tion and patte rn ofla
ii. What is the biochemical basis of clinical presenta (3)
.. / investigations in this case? (3+ 2)
disease
..M .,fafochemical basis and diagnosis of Sickle cell (1 +2+2)
ion.
4 PJinciple, types and applications of Polymerase chainent,react Add a note on dehydration
~ o w is body water distributed in various compartm (2+3 )
creatinine clearance and significance
y/o efi ne clearance. Describe the factors affecting (1 +2+2)
_ ~f creatinine clearance.
[Link]~ ~ith the enzyme defect.
!JI Enumerate the disorders ~f phenylalanine (2.5+2.5)
d with 1t.
Explain the biochemical basis of symptoms associate
.I Recombinant DNA technology and its application

x 10 Marks_= 10) . . .
(3+2)

Y , Long Answer Questions (Any one out of

two) (1
DNA rephcat10n and mh1b1tors of
a) Define replication of DNA mention its types of
(6+4)
replication.
• h ✓Describe vitam in D under the following
heads:
(2)
J ~o urc es and Recommended dietary allowance
(2) ..
y 3ynthesis
ations (3+3 )
~io che mic al functions and deficiency manifest

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