Nutrition DNA Test Sample Report
Nutrition DNA Test Sample Report
Sample Report
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
INTRODUCTION
Modern genetics is a rapidly advancing field. This expansion of self-
understanding has led to the amazing discovery that all humans share more than
99% of their DNA. It is in the < 1% variation that makes each of us unique from
everyone else in the world. Despite the common association of human genetics
with hereditary disorders and disease predisposition, this discovery has also led
to the understanding that no one approach to diet and fitness will work for
everyone. Most people who have seriously engaged in a diet and exercise plan
are likely already aware of this. The goal of this report is to offer an explanation
to these commonly held ideologies and provide answers to important questions
surrounding your diet, nutrition, exercise, and metabolism.
It is our hope that this report will be useful to anyone, regardless of his or her
current level of health or physical fitness. Whether you find yourself 40 pounds
overweight or have run two marathons in the past month, the information
contained in this report will help you live a healthier lifestyle and understand
how your body functions like never before, at the genetic level.
If after reviewing this report you have any questions, please feel free to contact us
regarding any aspect of this document. We also strongly urge you to review these
findings with your primary care physician and discuss any changes to your diet
or exercise plan before making any changes.
Thank you for giving us the opportunity to contribute to your overall health and
wellness!
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
TABLE OF CONTENTS
Dietary Requirements Nutritional Needs
Optimum Diet Type _____________ 3 Balanced Diet Calcium ________________________________ 21 Slightly Decreased Levels
Monounsaturated Fats _______ 4 Increased Benefit Copper __________________________________ 22 Possibly Increased
Sensitivity to Salt _______________ 5 Salt Tolerant Magnesium ___________________________ 24 Slightly Increased Levels
Omega-3 & Omega-6 _____________ 25 Typical
Eating Behaviors
Eating Disinhibition _____________ 42 More Likely
Tendency to Overeat ____________ 42 More Likely
Satiety ___________________________________ 43 Typical
Snacking _______________________________ 43 Typical
Bitter Taste ___________________________ 44 Bitter Taster
Umami Taste _________________________ 45 Average
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
BASICS OF BIOLOGY
To get the most out of this report it will be helpful to understand some commonly used terms in
biology. Please take a minute to read this section before moving on to the rest of your report!
Weight (lb)
88 132 176 220 265 309 353
2.0 6’7”
1.9 6’3”
1.8 5’11”
Height (ft, in)
Height (m)
1.7 5’7”
1.6 5’3”
1.5 4’11”
DIETARY REQUIREMENTS
In this section your optimum diet, the best diet to maintain optimal health, has been
determined by looking at several genes involved with fat and carbohydrate metabolism.
Based on these results, you have been assigned to one of the following diet types:
• Balanced Diet
• Mediterranean Diet
• Low Fat/High Protein Diet
• Low Carbohydrate Diet
We encourage you to review the example of popular diet types that match your genetic
recommendation (listed later in this report). Your suggested diet is recommended for you
because your genotype indicates that it will provide you with increased weight control and
additional health benefits. However, it is always recommended to discuss any change in
your diet plan with your primary health care provider. 51, 40, 27, 58, 59, 60, 61, 63
BALANCED DIET
A balanced diet will help you get the right amount of foods to reach your goals and find
optimal health. What does a balanced diet look like? Instead of counting calories, simply
use your hand as a guide to “measure” the food on your plate. With each meal/snack, you
will aim to include lean protein and vegetables. With most meals you can also include
what we like to refer to as “smart carbohydrates”. Smart carbohydrates are whole food
carbohydrates that give you lots of nutrition in the form of vitamins, minerals, and fiber.
Also, with most meals, you can include a healthy fat. You will also want to include healthy
fats that come from whole food sources.
MEDITERRANEAN DIET
The Mediterranean diet is often called a heart-healthy eating plan. It includes a wide
variety of fruits, vegetables, fish, whole grains, and healthy fats. This diet has been
associated with low levels of low density lipoprotein (LDL) cholesterol, also known as the
“bad” cholesterol. Research with the Mediterranean diet has been shown to reduce the risk
of heart disease, cancer, diabetes, Alzheimer’s, and Parkinson’s diseases.
Suggested Macros
• Beef (look for extra lean cuts; • Broccoli iceberg) • Natural peanut butter;
90% or greater with 10% or less • Brussels • Mushrooms natural nut or seed butters
of fat) sprouts • Onions (almond, cashew, etc.)
• Chicken/Turkey: eat white • Cabbage • Radishes • Nuts/seeds (almonds,
meat, with skin removed. If • Carrots • Snap peas cashews, chia, ground flax,
you choose ground chicken, • Tomatoes hemp, pecans, pumpkin,
• Cauliflower
look for 97% or greater as they • Turnips sunflower, walnuts)
• Celery
will grind the whole chicken in • Yellow • Cold-pressed oils (avocado
• Cucumbers
other versions that will give Squash oil, coconut oil, fish oil, olive
you more fat from the dark • Green beans • Zucchini oil, flax seed oil, hemp seed
meat and the skin. • Peppers oil, pumpkin seed oil) Fat
• Eggs/egg whites: Limit the • Limit or replace butter with
Carbs 35%
SMART CARBOHYDRATES
amount of yolks you use to one cold-pressed oils
yolk; this is where the fat comes
from and it is mainly saturated Be sure to count the fats you
45%
fat • Barley used to prepare your food as
• Fish to include: tuna, salmon, • Corn well as any used in dressings or
• Oats
tilapia, cod, haddock, trout. Eat
once or twice a week. • Potatoes (purple, red, or gold)
sauces. Protein
• Seafood: shrimp, scallops, crab • Quinoa
• Rice (brown, red, or wild) 20%
(not imitation)
• Dairy: milk, cottage cheese, • Squash
plain/Greek yogurt (look for • Sweet potatoes/yams
lower fat versions of all) • Fresh or frozen fruit
• Protein powders
• Beans and lentils
LOW-FAT DIET
Eating the right kinds of fat in the right amounts are important for hormone regulation, healthy immune
system, vitamin absorption, nourishing your fatty tissues (brain, eyes, skin), and for faster workout recovery.
There are several different kinds of fats and how much fat you eat is just as important as balancing the type of
fats you eat. Equally important is that your fats come from a variety of whole unprocessed foods when possible
(eggs, meats, fish, olives, nuts, and seeds). This will help optimize health, body composition, and performance.
Fats are energy dense. This means they have more calories per gram than carbohydrates and protein.
With a low-fat diet, you don’t have to get fat at every meal. With each meal/snack, you will want to include lean
protein and vegetables. Lean proteins will have the fat trimmed from it and the skin removed. With most
meals you can also include what we like to refer to as “smart carbohydrates,” which are whole food
carbohydrates that give you lots of nutrition in the form of vitamins, minerals, and fiber.
LOW-CARB DIET
Carbohydrates are essential for life and the nutrient our body prefers to use for energy. Our brains and
nervous system need a continuous supply of glucose (sugar in the blood) to feed the cells and function
optimally. By starting a lower carbohydrate diet, you are looking at a diet that will you give you the right
amount of foods to reach your goals and find optimal health. Instead of completely eliminating carbohydrates
like many fad diets instruct, it’s healthier to move to BETTER carbohydrates. We often reference these better
carbs as “smart” carbohydrates.
With a low carb diet, you don’t have to have carbohydrates at every meal. With each meal/snack, you will aim
to include lean protein and vegetables. With most meals you can also include a smart carb. Just be sure you
are aiming for whole food sources to give you lots of nutrition in the form of vitamins, minerals, and fiber.
Also, with most meals, you can include a healthy fat. You will also want to include healthy fats that come from
whole food sources.
MONOUNSATURATED FAT
POLYUNSATURATED FAT
SALT SENSITIVITY
The amount of dietary salt consumed has long been known to contribute to high blood
pressure, also known as hypertension. But some people are more sensitive to salt than
others, meaning they may experience a greater increase in blood pressure after consuming
a large amount of salt. This difference comes down to mutations in the genes that control
the renin-angiotensin system (RAS), a hormone system that regulates blood pressure.
Several genetic mutations are known to alter the functions of both angiotensin and ACE
and increase the risk of hypertension. Genetic variants in the ACE, AGT, and NOS3 genes
have the possibility of making a person much more salt-sensitive, which could result in an
elevation of blood pressure following salt intake.83, 84, 85 If your results in this section
suggest you could be salt-sensitive, speak with your physician about ways to monitor your
blood pressure and consider low-sodium alternatives when cooking or dining out.
Nearly everyone knows someone with a “fast metabolism,” maybe you are even one
yourself! These people are usually described as being able to eat whatever they want
without gaining a pound. The term metabolism describes how your body breaks down and
utilizes the calories you consume. Resting metabolism describes how your body uses
energy during rest, as any type of exercise will generally increase your metabolic rate.
There are many different factors that can regulate your metabolism, but recent genetic
findings have uncovered a marker in the LEPR gene that can influence your metabolic
rate. The study revealed that individuals with two copies of the "C" allele are more likely to
have a significantly increased resting metabolic rate, while individuals with other
genotypes are likely to have a “Normal” metabolic rate. However, it is important to
remember that your metabolism is ultimately not controlled by only one gene, but is rather
a consequence of your diet, genetics, and daily activities.67
move more
5 WAYS TO
lift more
BOOST YOUR
drink more
METABOLISM
sleep more
eat more
Weight control and the loss of body fat are one of many benefits that result from regular
exercise. For many people, burning excess fat is their primary fitness goal. Given this, it
may be surprising to learn that not everyone burns fat equally during exercise. A genetic
variant in the LPL gene has been associated with how much fat is burned during exercise.
Individuals with one or more “G” alleles at position rs328 in the LPL gene have been shown
to have an “Enhanced” ability to burn fat as a result of exercise. Of course, if you lack this
genetic variant you will still lose fat in response to exercise, but be aware that it may take a
little more effort as compared to others with this variant.2
RESPONSE TO DIETING
Adiponectin is a hormone released from fatty tissue that is known to contribute to a variety of
different metabolic processes, including the regulation of blood sugar and the breakdown of
fatty acids. Levels of adiponectin are known to be inversely related to body fat, meaning that
the more adiponectin you have circulating in your blood, the less likely you are to have
excessive body fat. A study identified a genetic variant in the ADIPOQ gene that resulted in
higher levels of adiponectin with one or more copies of the A allele at position rs17300539.
Moreover, the study also identified individuals with one or more copies of an "A" allele to
have better and more long-lasting results from a calorie-restricted diet with regards to
metabolic markers, such as insulin and triglyceride levels. Participants in the study who had
one or more copies of the "A" allele were also shown to maintain these benefits of dieting for a
much longer period of time as compared to "G/G" participants.28, 37
Unfortunately, many individuals find that it is difficult to keep the pounds off following a
successful weight loss program. This may be due to a regression in diet and exercise, but
your genetics also play a part in how likely you are to gain weight back after losing it. A
recent study identified a genetic variant in the ADIPOQ gene that influences weight loss.
People who have two copies of the "G" allele at this location have been found to be more
likely to gain weight back following a weight loss program, while individuals without this
genotype are more likely to maintain their weight loss. Regardless of your genotype, it is
important to maintain a healthy diet and active lifestyle following any weight loss program
to ensure the pounds stay off. 28 Exercise & Weight Loss | Page 9
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
It is well known that not everyone metabolizes food in the same manner. This is probably
most evident when you are trying to lose weight through dieting. It is also evidenced by
the never-ending feud that exists between rival diet programs such as paleo and Atkins.
What most individuals do not realize is that not every diet will work for every person. Just
because your good friend had amazing results from Atkins does not mean that it will work
for you. This section of the report is based on research that has been performed on the two
most popular approaches to weight loss, a low-fat vs. a low-carb diet. Based on your
genotype at three different locations, you are predisposed to having one diet work better
for you than the other. Researchers have found that people who have subscribed to
the correct diet based on their genotype lose 2.5 times more weight than if they were
practicing the alternative diet. Some individuals have also been shown to have good
results, regardless of diet type. Based on your results at the following three locations, you
will receive one of the following outcomes:
If you have struggled with finding the right diet for weight loss in the past, then you may
want to consider trying again with the diet suggested for you in this panel. It should also
be stressed that any diet will work if it is supplying the correct caloric and vitamin intake.
Be sure to discuss any significant changes in your diet with your primary healthcare
provider before beginning a new program. 20, 10, 5, 1, 13, 8
LOW-FAT DIET
Eating the right kinds of fat in the right amounts are important for hormone regulation, healthy immune
system, vitamin absorption, nourishing your fatty tissues (brain, eyes, skin), and for faster workout recovery.
There are several different kinds of fats and how much fat you eat is just as important as balancing the type of
fats you eat. Equally important is that your fats come from a variety of whole unprocessed foods when possible
(eggs, meats, fish, olives, nuts, and seeds). This will help optimize health, body composition, and performance.
Fats are energy dense. This means they have more calories per gram than carbohydrates and protein.
With a low-fat diet, you don’t have to get fat at every meal. With each meal/snack, you will want to include lean
protein and vegetables. Lean proteins will have the fat trimmed from it and the skin removed. With most
meals you can also include what we like to refer to as “smart carbohydrates,” which are whole food
carbohydrates that give you lots of nutrition in the form of vitamins, minerals, and fiber.
LOW-CARB DIET
Carbohydrates are essential for life and the nutrient our body prefers to use for energy. Our brains and
nervous system need a continuous supply of glucose (sugar in the blood) to feed the cells and function
optimally. By starting a lower carbohydrate diet, you are looking at a diet that will you give you the right
amount of foods to reach your goals and find optimal health. Instead of completely eliminating carbohydrates
like many fad diets instruct, it’s healthier to move to BETTER carbohydrates. We often reference these better
carbs as “smart” carbohydrates.
With a low carb diet, you don’t have to have carbohydrates at every meal. With each meal/snack, you will aim
to include lean protein and vegetables. With most meals you can also include a smart carb. Just be sure you
are aiming for whole food sources to give you lots of nutrition in the form of vitamins, minerals, and fiber.
Also, with most meals, you can include a healthy fat. You will also want to include healthy fats that come from
whole food sources.
OBESITY
Depending on your results from this section, you may find that if you have ever struggled
with weight then there may be a contributing genetic factor, especially if you do not eat a
healthy diet and regularly engage in a suitable form of exercise. Conversely, individuals
who have a lower risk of obesity are not immune from becoming obese and still need to
routinely engage in healthy lifestyle choices.
Exercise & Weight Loss | Page 11
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
HDL CHOLESTEROL
HDL
High Density Lipoprotein
LDL
Low Density Lipoprotein
GOOD CHOLESTEROL BAD CHOLESTEROL
High Density Lipoprotein carries excess Low Density Lipoprotein carries cholesterol to
cholesterol in your blood back to your liver where your cells. But when you have too much LDL, it
it’s broken down and removed from your body. can build up in your artery walls, causing them
This means a high level of good HDL cholesterol to narrow. This reduces blood flow, which can
can maintain your heart health. be bad for your heart health.
Metabolic Health Factors | Page 13
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
LDL CHOLESTEROL
OLYHU
+'/
/'/
FKROHVWHURO
GHSRVLW SODTXH
DUWHU\
Metabolic Health Factors | Page 14
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
TRIGLYCERIDE LEVELS
Your level of blood sugar refers to the amount of glucose that is circulating in your
bloodstream. Blood sugar levels are carefully regulated by the body, but fluctuate greatly
throughout the day in response to activity and food intake. Typical blood sugar
measurements for a healthy individual range from 70-100 mg/dL, depending largely on
when your last meal was. Blood sugar levels higher than this can result in a diagnosis of
prediabetes or diabetes depending on when the test was performed in relation to your last
meal. In addition to diabetes, high blood sugar is closely associated with several negative
health outcomes, including cardiovascular problems, kidney disease, vision loss, and nerve
damage. As with the other metabolic traits that have been discussed in this section, blood
sugar levels are subject to a wide variety of factors, including diet, exercise, and genetics.
This panel investigates five different genes that have been identified in clinical genetic
studies to correspond to blood sugar levels.91-95 Depending on the outcome of your test, you
may be predisposed to have blood sugar levels that are “Likely Lower,” “Possibly Lower,”
“Average,” “Possibly Increased,” or “Likely Higher.” It is important to note that these test
results are not a substitute for an actual blood glucose test, but are an indication of your
genetic predisposition.
OXIDATIVE STRESS
When food is metabolized by the body harmful substances known as "free radicals" are
produced during the process. These molecules, such as hydrogen peroxide, are known
to have damaging properties to cellular health. However, the body is prepared for this
and produces several different enzymes to counteract the damaging effects of free
radicals. Certain foods, rich in Vitamins C, A, and E, are also known to reduce levels of
free radicals. Collectively, these substances are known as antioxidants. A recent study
has identified a genetic variation that can influence the levels of one important
antioxidant, referred to as SOD2. If you have one of more copies of the "A" allele at SNP
rs4880 you may have lower levels of the SOD2 enzyme and are at a higher risk for
increased oxidative stress. If your genotype indicates that you have reduced SOD2
activity you should try and include more foods that are rich in antioxidants into your
diet, such as blueberries, dark chocolate, kidney beans, and artichokes. 4
-- - -
-
- - -
- -
-
- - - - -
- - - -
- Unpaired - - -
Electron - - -
Free Radical Antioxidant
DETOXIFICATION
• Cigarette Smoke
• Insect Sprays
• Herbicides
• Charred Foods
• Heavy Metals
• Fungicides
Of course, all of us should make an effort to avoid these substances, but individuals with
this genetic marker may want to consider the use of an all natural insecticide, avoid
smoking, and consider organic foods.9, 15, 27, 69
IRON LEVELS
Iron is one of the essential micronutrients required by our bodies. Among other important
biological roles, iron is required for oxygen transport in our blood—it helps to bind the
oxygen molecules to the red blood cells so the oxygen can be moved around our body from
our lungs to where it is needed. There are two types of dietary iron: heme and nonheme.
Heme iron is contained in meat; sources that are especially high include red meats,
shellfish, and liver. Nonheme iron is found in eggs, tofu, spinach, and legumes, and it is
what manufacturers use to fortify cereals, breads, and pastas. Our bodies absorb heme
iron much more readily than nonheme, meaning that if you’re a vegan or vegetarian, your
recommended daily allowance (RDA) of iron is 1.8 times higher than a person of your same
age and gender who regularly eats meat. Pregnant women need significantly more iron in
order to support the baby’s growth as well as maintain the blood-rich placenta.
Because iron is so important and we can only get it from our diet, our bodies are really
good at absorbing iron from our food, but we don’t have any way of getting rid of too much
iron—the only way our bodies have of controlling our iron levels is regulating how much
iron gets absorbed. Once our body thinks it has all the iron it needs, it will stop absorbing
it from our food. Some people have a genetic mutation that prevents the absorption
process from shutting off, resulting in an accumulation of excess iron.
This genetic mutation occurs in the HFE gene and having at least one mutated allele is
common in those of European ancestry. Approximately 10% of Caucasians have a single
mutation, meaning they are carriers, but only 0.4% are homozygous for the mutation and
are more likely (though not guaranteed) to develop excess iron levels.79-82 Having
mutations in other genes that code for iron processing proteins increases those chances.
(These mutations are much less common in other ethnic groups.) If your results in this
section suggest you may be likely to accumulate excess iron, speak with your doctor about
ways to keep an eye on your iron levels.
YOUR RESULTS:
NUTRITIONAL NEEDS
Calcium –
Slightly Decreased Levels
Copper –
Possibly Increased
Folate –
Balanced Intake
Magnesium –
Slightly Increased Levels
Vitamin A –
Many people are not aware that your genes play a critical
Increased role in how your body utilizes and metabolizes different
Vitamin B2- vitamins. There are 13 different vitamins and at least 16
Balanced Intake different minerals that are critical for human health. The
body needs these compounds for a wide variety of tasks,
Vitamin B6 – including enzymatic reactions, proper hormone function,
Likely Reduced cell signaling, reproduction, and growth. While it is easy to
take a multivitamin, there is a growing body of knowledge
Vitamin B12 – that many vitamins are not readily absorbed by the body in
Likely Reduced this fashion. Additionally, some individuals metabolize
vitamins differently and may require additional intake of
Vitamin C – some key nutrients. The intent of this section is to better
Increased inform you of what vitamins and nutrients you need to
focus on obtaining in your diet. Experts agree that the best
Vitamin D – source of virtually every vitamin and mineral is dietary.
Normal Given this, we provide food recommendations for each key
nutrient that is discussed in this section, in addition to the
Vitamin E – daily recommended allowances (RDAs) that are suggested
Average by the Institute of Medicine of the National Academies.
Zinc –
Average Levels
Nutritional Needs | Page 20
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
CALCIUM
YOUR
YOUR RESULT: GENE SNP
GENOTYPE
Slightly Decreased Levels CASR rs1801725 GG
Your results indicate that you may be CASR rs17251221 AA
genetically predisposed to having slightly DGKD rs1550532 CC
lower serum levels of calcium. GCKR rs780094 CC
GATA3 rs10491003 CC
CARS rs7481584 AG
Calcium is the most abundant mineral in the
human body. It plays vital roles in the vascular
DGKH rs7336933 GG
system, muscle function, nerve transmission, and CYP24A1 rs1470669 AA
hormone secretion, but only 1% of the body’s total
calcium is involved in these functions. The
remaining 99% of the calcium in the body is stored Recommended Daily Allowance for Calcium
in bones and teeth, where it supports their
Age Male Female
structure and function as well as serving as a
storage location the body can pull from when it 1-3 years 700 mg 700 mg
needs it. In fact, bones are constantly remodeling 4-8 years 1,000 mg 1,000 mg
themselves by depositing and reabsorbing calcium.
9-13 years 1,300 mg 1,300 mg
When we’re young, more new bone is made than
old bone is removed, so our bone mass increases 14-18 years 1,300 mg 1,300 mg
until around age 30, after which point we usually 19-50 years 1,000 mg 1,000 mg
begin to lose bone mass. The older we get, the more
51-70 years 1,000 mg 1,200 mg
our bone density decreases, and we become more
prone to fractures and breaks, especially during 71+ years 1,200 mg 1,200 mg
physical activities.
Calcium deficiency has no short-term effects as such a small amount is needed for vital biological
processes and the body has such a large store in its bones. However, long-term calcium deficiency can
result in bone loss later in life. Osteoporosis, a condition characterized by fragile bones and increased
fractures and breaks, is a serious public health concern as it affects over 10 million adults in the U.S.,
80% of whom are women. 34 million U.S. adults have osteopenia, which is the low bone mass that
precedes osteoporosis.115-117 Osteoporosis especially affects postmenopausal women as well as women
who are no longer having a regular menstrual period due to an eating disorder or extreme athletic
training. This is due to the changes in circulating estrogen levels, which impacts calcium absorption.
The healthiest way to increase calcium is to optimize your intake through your diet. Dietary sources of
calcium include dairy products like milk, cheese, and yogurt; fortified cereals and juices; and
vegetables like cabbage, kale, and broccoli. It’s also important to be sure you’re getting enough
vitamin D along with your calcium, as vitamin D helps your body absorb calcium. Calcium
supplements are common, but you should always speak with your physician before starting any
supplements because an excess of calcium can cause renal insufficiency, vascular and soft tissue
calcification, and kidney stones. Nutritional Needs | Page 21
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
COPPER
The recommended daily allowance of copper for adults is 0.9 mg/day, pregnant women is
1.0 mg/day, and breastfeeding women is 1.3 mg/day. Good sources of dietary copper
include whole grains, nuts, legumes, mushrooms, shellfish, and dark chocolate. If you’re
concerned you aren’t getting enough copper, you should speak with your physician about
your nutritional needs before taking a supplement because long-term excess dietary
copper can result in copper toxicity, which can have negative effects on liver and kidney
function.
FOLATE
Folate is derived from the Latin word Recommended Daily Allowance for Folate
“folium,” which means leaf. Green leafy Age Male Female
vegetables, such as spinach or kale, as well 1-3 years 150 mcg DFE 150 mcg DFE
as beans, fruits, fortified grains, and lentils 4-8 years 200 mcg DFE 200 mcg DFE
are great resources for folate intake. Diets 9-13 years 300 mcg DFE 300 mcg DFE
that are rich in folate can even decrease the 14+ years 400 mcg DFE 400 mcg DFE
risk of cardiovascular disease. Daily intake The current RDAs for folate are given as micrograms
of folate is highly recommended for (mcg) of dietary folate equivalents (DFEs). The FNB
developed DFEs to reflect the higher bioavailability of
pregnant women or those who intend to folic acid than that of food folate. At least 85% of folic
become pregnant. Adding folate is highly acid is estimated to be bioavailable when taken with
important in the early stages of pregnancy food, whereas only about 50% of folate naturally
since it is known to prevent some birth present in food is bioavailable. Based on these values,
the Food and Nutrition Board (FNB) defined DFE as
defects. It is for this reason that women follows:
who are pregnant or plan to become
pregnant should increase their daily intake 1 mcg DFE = 1 mcg food folate
of folate. 1 mcg DFE = 0.6 mcg folic acid from fortified foods or
dietary supplements consumed with foods
Given its importance, it is beneficial to know 1 mcg DFE = 0.5 mcg folic acid from dietary
supplements taken on an empty stomach
how your body metabolizes the folate that you
ingest. Two well-studied variants in the MTHFR gene have been linked to altered folate
metabolism, resulting in lower folate levels and elevated plasma levels of homocysteine
which has been implicated in a wide range of negative health outcomes. If your result for
this section is to "Optimize Levels" then you should strongly consider optimizing your
daily intake of folate. However, it is recommended to focus on foods that are rich in folate,
as opposed to the synthetic form, folic acid. It is important to note that not all individuals
with this genotype have a vitamin imbalance, but many do and you should consider
discussing these results with your primary care physician.24, 71
MAGNESIUM
Magnesium deficiency in healthy individuals is rare because the kidneys do a good job of
controlling the excretion.119 However, those with gastrointestinal diseases, diabetes, or
alcohol dependence may have difficulty absorbing adequate amounts of magnesium.
Symptoms of chronic magnesium deficiency include numbness, tingling, muscle cramps,
seizures, and heart problems. Excess magnesium is also rare for the same reason, the
kidneys control excretion of excess amounts. However, high doses from supplement use
have been found to cause nausea, cramping, and diarrhea. Patients with impaired renal
function or kidney failure are at risk of magnesium toxicity. Magnesium supplements can
also interact with certain medications, such as antibiotics, diuretics, and proton pump
inhibitors, so supplement use should always be discussed with your physician.
The recommended daily allowance of magnesium for healthy adults is 400-420 mg/day for
men and 310-320 mg/day for women, with higher levels for pregnant women to help
support the developing fetus. Foods high in magnesium include nuts, green leafy
vegetables, legumes, and whole grains.
Both omega-3 and omega-6 fatty acids are classified as polyunsaturated fats. In
moderation, polyunsaturated fats are considered necessary and healthy. Many studies
have even linked the ingestion of foods rich in omega-3 and omega-6 fatty acids to a
reduced risk of cardiovascular disease.18 Excellent sources of omega-3 fats are fish,
flaxseed, canola oil, walnuts, hemp seed, and dark green leafy vegetables. Foods rich in
omega-6 fatty acids include corn, safflower, soybean, and sunflower oils. A marker in the
FADS1 gene has been linked to inefficient processing of omega-3 and omega-6 fats.
Individuals who have a genotype of "G/A" or "G/G" have a potentially increased risk for
decreased plasma levels of these beneficial fats. It is important to note that results such as
these do not directly indicate a deficiency, but only suggest that you are predisposed to
developing one. If this is your genotype you should try to optimize your intake of these
polyunsaturated fats, within the limits of your diet plan.64
PHOSPHORUS
Phosphorus is required for the structure and Recommended Daily Allowance for Phosphorus
function of every cell in the human body. Age Male Female
Phosphorus helps form the membrane around 1-3 years 460 mg 460 mg
each cell, is an important part of the DNA 4-8 years 500 mg 500 mg
molecule, and even helps your body process 9-13 years 1,250 mg 1,250 mg
energy. On a larger level, phosphorus is also 14-18 years 1,250 mg 1,250 mg
required for the structure of teeth and bones 19+ years 700 mg 700 mg
and it helps kidneys filter waste. Phosphorus
is necessary for muscle contraction, so it’s not only important for movement, but also
digestion via the contraction of the smooth muscles in the digestive tract as well as
keeping the heart beating through contractions of the cardiac muscles.
Phosphorus deficiency is very rare but some medications can lower the body’s levels of
phosphorous.118 These medications include insulin, ACE inhibitors, corticosteroids,
antacids, and anticonvulsants. Most people get more than the necessary amount of
phosphorous in their diets—many foods are high in phosphorus and phosphorus is also
often added during food processing. Healthy kidneys do a great job at removing excess
phosphorus, but those with chronic kidney disease (CKD) may develop excess levels of
phosphorus, which can result in bone loss as the body pulls calcium from the bones to
bind the excess phosphates in the blood and then that calcium gets deposited in blood
vessels and other organs like the heart and lungs, causing dangerous calcification of these
organs. This is only a concern for those with CKD, and those patients should discuss their
nutritional needs with their physician and consider a low-phosphorus diet. Medications
are also available that can bind the excess phosphorus and prevent it from being
absorbed.
The recommended daily allowance of phosphorus for healthy adults is 700 mg/day.
Sources of phosphorus include dairy products, meats, nuts, and beans. Additionally,
processed foods like fast food and soda often contain high levels of added phosphorus.
SELENIUM
Chronic excess selenium intake can result in hair and nail loss, skin lesions and rashes,
fatigue, irritability, and nervous system abnormalities. For these reasons, consult your
physician before taking any supplements.
The recommended daily allowance of selenium for adults is 0.55 mg/day. The best sources
of dietary selenium are seafood, meat, and fortified cereals and dairy products. The
selenium content in plants and grains can vary widely across geographic regions due to
differences in soil concentrations of selenium.
VITAMIN A
VITAMIN B2
Vitamin B2 is also known as riboflavin. All of Recommended Daily Allowance for Vitamin B2
the B vitamins play an important role of Age Male Female
converting food into fuel to give our bodies the 1-3 years 0.5 mg 0.5 mg
energy it needs. Riboflavin also works as an 4-8 years 0.6 mg 0.6 mg
antioxidant, fighting free radicals that can 9-13 years 0.9 mg 0.9 mg
damage your cells and DNA. Fatigue, digestive 14-18 years 1.3 mg 1.0 mg
problems, and sensitivity to light are a few 19+ years 1.3 mg 1.1 mg
examples of a riboflavin deficiency. Vitamin
B2 also functions as an important cofactor (helper molecule) for an enzyme that is
responsible for metabolizing folate encoded by the MTHFR gene. Individuals who have a
genotype of "A/A" at position rs1801133 are at a higher risk of altered folate metabolism if
they are deficient in vitamin B2. If this is your genotype you need to ensure that you are
receiving the recommended daily allowance of riboflavin based on your age and sex.
Individuals without this genotype should still strive to ingest the recommended daily
amounts of Vitamin B2, as altered folate metabolism is by no means the only negative
health outcome associated
ssociated with riboflavin deficiency.65,70
GOOD
SOURCES
OF
B2
VITAMIN B6
VITAMIN B12
If you are showing signs of fatigue, weakness, Recommended Daily Allowance for Vitamin B12
bloat, or numbness or tingling in your hands or Age Male Female
feet, these are symptoms of vitamin B12 1-3 years 0.9 mcg 0.9 mcg
deficiency. Vitamin B12 plays a large role in the 4-8 years 1.2 mcg 1.2 mcg
operation of the nervous system, DNA synthesis, 9-13 years 1.8 mcg 1.8 mcg
and red blood cell function. The best sources of 14+ years 2.4 mcg 2.4 mcg
vitamin B12 are meat, fish, poultry, eggs, and
milk products. Given this, vegans and vegetarians need to monitor their vitamin B12
carefully. The elderly and those with digestive disorders may also have trouble getting
enough vitamin B12, as it is absorbed in the gastrointestinal tract. Recently, a
polymorphism in the FUT2 gene has been linked to decreased plasma levels of vitamin
B12. Individuals who have two copies of the "G" allele at position rs602662 are at a higher
risk for being deficient in vitamin B12, while individuals with only one ''G" allele are more
likely to have average plasma levels. If your genotype indicates that you are at an
increased risk for vitamin B12 deficiency then you should try and maximize your intake
by eating a diet rich in the aforementioned food as well as fortified cereals. Those without
the "G" allele should continue to eat a balanced and healthy diet to maintain a proper
balance of Vitamin B12. 43, 25
B12
Healthy Healthy
Blood Nerves
VITAMIN C
Vitamin C, also known as l-ascorbic acid, has Recommended Daily Allowance for Vitamin C
many important jobs in the body. It is a critical Age Male Female
dietary component to the synthesis of collagen 1-3 years 15 mg 15 mg
which keeps skin firm and youthful looking as 4-8 years 25 mg 25 mg
well as playing a critical role in wound healing. 9-13 years 45 mg 45 mg
Vitamin C is also important for the production 14-18 years 75 mg 65 mg
of certain neurotransmitters, contributes to 19+ years 90 mg 75 mg
protein synthesis, and is an important
antioxidant. It even helps regenerate other antioxidants like vitamin E. It also aids the
body’s absorption of nonheme iron, the dietary iron found in non-meat foods like spinach
and legumes.
Vitamin C is one of many vitamins that the human body is not able to produce; therefore,
it is vital to ensure that you are receiving enough through dietary sources. The best
sources of Vitamin C are from fresh fruits and vegetables. Some of the highest sources of
Vitamin C include guavas, bell peppers, kiwi, strawberries, broccoli, and oranges. Given
that Vitamin C is also a powerful antioxidant, deficiencies in Vitamin C have been linked
to multiple disorders including muscle pain, fatigue, swollen gums, and slow wound
healing. Most adults need to ingest between 75-90 milligrams of Vitamin C per day to
maintain optimum levels. However, multiple studies have indicated a mutation in the
SLC23A1 gene is linked to decreased levels of Vitamin C in the blood.89 If your results for
this section indicate that you are predisposed to having lower than average levels of
Vitamin C, you should make an extra effort to consume more fresh fruits and vegetables
on a daily basis.
VITAMIN D
Vitamin D has many roles in the body. It Recommended Daily Allowance for Vitamin D
promotes calcium absorption in the gut, is Age Male Female
needed for bone growth, and even reduces 1-70 years 15 mcg 15 mcg
inflammation. If the body does not get the 70+ years 20 mcg 20 mcg
sufficient amount of vitamin D, bones can
become brittle and thin. It even helps to prevent osteoporosis in older adults. Great
sources of vitamin D include fatty fish, fish liver oils, and milk. Regular exposure to
moderate amounts of sunlight is also critical to maintaining a healthy level, as sunlight
helps the skin synthesize vitamin D. In the United States, vitamin D deficiency is relatively
common largely due to limited sun exposure.
However, there is also a common marker in the GC gene that can predispose an individual
to decreased plasma levels of vitamin D. Individuals with a "C/C" or "C/A" genotype
produce an alternate form of a protein that binds and prevents vitamin D from circulating
throughout the body. It is recommended that people with this genotype need to try and
enhance their intake of foods rich in vitamin D and get regular, healthy exposure to
natural sunlight. For most people, simply 10 minutes of midday sunshine without
sunscreen is enough to produce a sufficient amount of vitamin D. Individuals with a
genotype of "A/A" should still focus on maintaining vitamin D levels, as it is one of the
easiest vitamins to become deficient in. 38,52
VITAMIN E
Vitamin E is a collective term for a number Recommended Daily Allowance for Vitamin E
of compounds referred to as tocopherols or Age Male Female
tocotrienols, but alpha-tocopherol 1-3 years 6 mg 6 mg
(ɑ-tocopherol) is the most biologically active 4-8 years 7 mg 7 mg
form. Vitamin E is one of the most important 9-13 years 11 mg 11 mg
natural antioxidants. It is lipid soluble, so it 14+ years 15 mg 15 mg
embeds itself within cell membranes to protect
those cells from free radicals. Excess vitamin E is stored within fat cells. Because of
this solubility, the best dietary sources of vitamin E contain a high percentage of fat,
such as cooking oils (sunflower oil, canola oil, olive oil, etc.); nuts like almonds,
peanuts, and pistachios; and spreads like peanut butter, margarine, and mayonnaise.
Not everyone absorbs the same amount of vitamin E as others though, and that may be
due to genetic differences. The SNP rs12272004 has been associated with ɑ-tocopherol
levels.86, 87, 88 If your genotype at this location suggests you may be prone to lower
levels of vitamin E, try to optimize your levels by incorporating more foods into your
diet that are rich in vitamin E.
+D]HOQXW $OPRQG6XQIORZHU3HDQXW
6HHGV
ZINC
Zinc is the second most abundant trace metal after iron Recommended Daily Allowance for Zinc
and is critical for growth and development in Age Male Female
pregnancy and childhood. Zinc is involved in a wide
range of biological processes including immune
1-3 years 3 mg 3 mg
function, protein synthesis, wound healing, DNA 4-8 years 5 mg 5 mg
synthesis, and cell division, and it is required for the 9-13 years 8 mg 8 mg
senses of taste and smell. Unlike other micronutrients, 14-18 years 11 mg 9 mg
the body has no way of storing zinc so it is important to 19+ years 11 mg 8 mg
get adequate amounts of zinc through one’s dietary
intake.
Zinc deficiency is uncommon in developed countries, but can be found among those with digestive or other
chronic disorders that inhibit absorption or increase loss of zinc, such as Crohn’s disease, chronic liver or
renal disease, and diabetes, among others.114 There is some concern that vegetarians may be at a higher risk
of zinc deficiency than meat eaters because the zinc contained in non-meat sources has a lower
bioavailability, meaning the body can’t use it as efficiently as the zinc found in meat. Additionally,
compounds found in legumes and whole grains (common staples of vegetarian diets) can bind to zinc and
prevent its absorption. Despite this, vegetarians in developed countries have not been found to have overt
zinc deficiency, though their levels do tend to be lower than meat eaters.
Zinc deficiency’s most apparent symptom is an impaired immune system, resulting in a higher rate of
infections among children and the elderly whose immune systems are already not as strong as most adults’.
Zinc levels may also contribute to the longevity of bouts of the common cold. Studies have found that taking
a zinc supplement when patients come down with a cold significantly shortened the duration of symptoms,
however most researchers agree that more data is needed to determine optimal dosages.
Zinc interacts with iron and copper, so it’s important to keep the levels of these three trace nutrients in
balance. High levels of supplemental iron can decrease zinc absorption. High levels of zinc intake can result
in copper deficiency and cause anemia. For healthy individuals, maintaining a balanced diet is enough to
keep these micronutrients at optimal levels. Zinc supplements can interact with certain medications, so it’s
important to discuss your supplement use with your physician. Zinc is known to interact with certain
classes of antibiotics, inhibiting the absorption of both. Zinc can also interact with certain diuretics and
result in increased zinc excretion, depleting zinc levels.
The current recommended daily allowance of zinc for adult women is 8 mg/day, for men and pregnant
women is 11 mg/day, and for breastfeeding women is 12 mg/day. The best sources of zinc include shellfish,
red meat, and poultry. Vegetarian sources include fortified cereals, baked beans, yogurt, legumes such as
chickpeas, and nuts like cashews and almonds. Nutritional Needs | Page 35
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
REACTIONS TO FOOD
LACTOSE INTOLERANCE
Unbelievably, the ability to digest milk after childhood is considered a genetic adaptation. No other
species of animal on Earth retains the ability to digest milk in their adulthood, except for humans.
Not even all human adults can fully digest milk. The problem arises due to the lactose in milk not
being properly degraded by the enzyme lactase. So, if milk has never settled your stomach there
may be good reason why due to genetic differences in the MCM6 gene. Individuals with two copies
of the "G" allele at marker rs4988235 are far more likely to experience discomfort after eating dairy
products, while people with other genotypes are less likely to have side effects. Should you prove
to be lactose intolerant, it is important to make sure that you are receiving enough calcium from
other dietary sources.3
ALCOHOL FLUSH
While most people are capable of having the occasional drink, some individuals are known to
have a strong negative response to alcohol. Often referred to as alcohol flush, this condition is a
result of alcohol not being properly metabolized by the body. Primary symptoms include
reddening of the face, nausea and tachycardia (rapid heartbeat). The alcohol flush reaction is
caused by a buildup of acetaldehyde due to a defective enzyme encoded by the ALDH2 gene. So, if
you have negative reactions to alcohol, or suffer severe hangovers, your genes may be to blame.
Individuals who carry one or more copies of the "A" allele at position rs671 are far more likely to
experience negative side effects from drinking alcohol.11, 7 Reactions to Food | Page 37
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
CAFFEINE METABOLISM
Caffeine is by far the most widely consumed stimulant throughout the world. However, most
people are unaware that your DNA ultimately decides how your body metabolizes it. This is
due to a genetic variant that was located in the CYP1A2 gene at position rs762551. Depending
on the sequence of your DNA at this location, you will break down caffeine at different rates.
Individuals with a genotype of "C/C" or "C/A" will metabolize caffeine much slower than
individuals with an "A/A" genotype. If you are a slow metabolizer of caffeine you should try to
limit your total daily caffeine intake to less than 200 mg per day – or roughly two cups of
coffee. If you are a fast metabolizer of caffeine and are a healthy adult, we still suggest that
you try
y y and limit y
your dailyy intake of caffeine to no more than 400 mggpper day,
y, or
approximately 4 cups of coffee. 50
95 mg
82 mg
80 mg
27 mg
19 mg 20 mg
3 mg
GLUTEN SENSITIVITY
PEANUT ALLERGY
Many allergies develop in childhood, but it is not uncommon for an adult to develop a new
allergy to a food or medication. One of the most common developed food allergies is
peanuts. In a recent study published in the prestigious journal Nature, two SNPs near the
HLA genes were identified that increase your risk of developing a peanut allergy. Results
from this study indicate that depending on your genotype at these two locations you may
be upwards of six times more likely to develop a peanut allergy than an individual lacking
these variants.109 However, if your results from this section indicate an increased risk of
developing a peanut allergy it is not a guarantee that you will ever develop an additional
allergy. The results from this section only indicate your predisposition to developing
peanut allergy. If you have an increased risk you should watch for common food allergy
symptoms such as runny nose, itching or tingling around the mouth, shortness of breath,
digestive problems, and skin irritation after consuming peanut products.
Eating Behaviors
EATING DISINHIBITION
Eating disinhibition describes the tendency to excessively eat in response to a stimulus, such
as when you have a favorite meal, are under stress, or are out at a social gathering. A study
published in 2010 identified a single gene, TAS2R38, which is associated with this behavior.
The study revealed that individuals with an "A" allele at position rs1726866 were “More
Likely” to display eating disinhibition than an individual with only "G" alleles. 44
TENDENCY TO OVEREAT
tendency to overeat.
It is safe to say that nearly everyone will over eat at some point in their lifetime. Most often, it
is the result of a favorite meal or special event. However, some people overeat on a regular
basis which can lead to increased caloric intake and multiple negative health outcomes. The
tendency to overeat in some individuals is thought to occur as a result of how the brain
processes reward signals using neurotransmitters, such as dopamine. Similar mechanisms
have been hypothesized to predispose an individual to engaging in addictive behaviors. One
of the genes most closely associated with this is ANKK1-DRD2, which ultimately influences
how the brain uses dopamine. Individuals with an "A/A" or "A/G" genotype at this location are
considered to be more likely to overeat on a regular basis. Individuals with a "G/G" genotype
are not typically associated with overeating behaviors. If you are prone to overeating, you
may want to limit you portion size and avoid foods that are high in sugar and/or fat. 12
Eating Behaviors | Page 42
Report: Nutrition DNA Test
Name: Sample Report
Date: July 23, 2021
SATIETY
The term satiety is better described as the feeling of fullness that you experience after a meal.
However, not all individuals will feel equally full after eating an identical meal. This is partly due
to physical differences between individuals, but is also due to your genetic makeup. The best
studied genetic variant that contributes to satiety is rs9939609 in the FTO gene. Coined as “the fat
gene” in the media, the FTO gene plays a large role in several obesity-related disorders. Individuals
with two copies of the "A" allele at this location are considered more likely to experience hunger
after a meal, while individuals with one or two copies of the "T" allele are more likely to feel full. If
you have difficulty feeling full after a meal you may want to consider increasing the amount of
fiber in your diet and eating healthy snacks throughout the day. 23
SNACKING
YOUR
GENE SNP
GENOTYPE
rs2025804 AG
YOUR RESULT:
LEPR
Typical
Your genotype is not typically associated
with excess snacking.
While typically viewed as an unhealthy behavior, healthy snacking throughout the day can be an
effective way to reduce hunger cravings and the tendency to overeat. However, unhealthy
snacking can undoubtedly lead to an increased calorie intake and subsequent negative health
outcomes. It is generally thought that the tendency to snack is largely controlled by the hormone
leptin, which helps your body to regulate the amount of food that you eat. Genetically, the LEPR
gene ultimately controls how leptin is processed in your body. Individuals with two copies of the
"G" allele at position rs2025804 are more likely to exhibit extreme snacking behaviors. If you are
predisposed to snacking more, then you may want to consider selecting healthy snacks throughout
the day. Additionally, when you are snacking try to eat slower and measure out your portions
before eating the snack. 14
UMAMI TASTE
Umami is a flavor that is often associated with Japanese cuisine, especially broths and
cooked meats. It is described as a savory flavor and the Japanese word translates to
“pleasant savory taste” or sometimes simply “delicious taste.” First described in the early
1900’s, it was discovered by a Japanese chemistry professor who observed that the taste of
dashi, a soup base made from seaweed and dried tuna flakes, was distinct from that of the
other four tastes known at the time (sweet, salty, sour, and bitter). The scientific
community debated the existence of this fifth taste until the mid-1980’s when more
research began to be done on umami. Further evidence was obtained in the early 2000’s
when distinct umami taste receptors were discovered.77,78
The main chemical molecule that creates the umami taste is glutamate. Glutamate, most
commonly found as its salt form monosodium glutamate (MSG), is present in many meats,
cheeses, mushrooms, certain vegetables, soy sauce, and green tea. MSG can also be added
to dishes in its pure form as a flavor enhancer. While many in the Western world believe
MSG to be dangerous and unhealthy, no scientific study has found any evidence of adverse
reactions and the FDA has given MSG the classification of GRAS, or “generally recognized
as safe.” In fact, MSG has a lower sodium content than table salt and so it can be a good
way to lower salt content while preserving flavor.
BITTER TASTE
You may have noticed that some people love the taste of foods and drinks like black coffee
or raw cabbage, while others can’t stand the bitterness of these things. While a lot of food
preferences are subjective and based on personal experiences or cultural norms, the
perception of bitterness has a strong genetic component.
Several SNPs within the TAS2R38 gene determine whether you are a “taster” or “non-
taster” of bitterness. If you have G alleles at rs176866 and rs10246939 and a C allele at
rs713598, you are a “taster,” which means that you are far more sensitive to certain
chemical compounds present in foods like phenylthiocarbamide (PTC) or 6-n-
propylthiouracil (PROP) than people who don’t have those alleles and you will perceive
these foods as more bitter.74, 75, 76 These foods include rhubarb, sauerkraut, dark beers,
coffee, certain cheeses, and cruciferous vegetables like cabbage, cauliflower, broccoli,
Brussels sprouts, and kale.
This ability to perceive certain foods as far more bitter than others has had both benefits
and drawbacks throughout human history: “tasters” may be able to sense potential toxins
and determine which foods may be poisonous or spoiled, but they may also tend to avoid
foods that have important nutritional content due to their bitter taste.
METHODOLOGY
Laboratory specimens associated with this report were analyzed using a DNA microarray.
Genomic DNA was extracted from the submitted specimen and amplified using whole genome
amplification techniques. The polymorphisms assayed in this report were targeted through
the use of oligonucleotide primers. Single nucleotide polymorphisms were determined by
fluorophore-based detection of a labeled probe hybridized to the complementary target
sequence.
LIMITATIONS
This test detects polymorphisms other than those listed in this report. Polymorphisms not
detected in this analysis include known mutations that result in an altered predisposition to
the conditions discussed in this report. The absence of a detectable gene variant or
polymorphism does not rule out the possibility that the test subject has an increased chance of
developing any conditions discussed here. In very rare circumstances, polymorphisms in the
primer or probe binding site may affect genotyping results. This test does not identify non-
genetic factors that may contribute to an individual’s predisposition to developing any of the
conditions discussed in these findings. This test has not been approved by the United States
Food and Drug Administration (FDA) and should not be used as the sole evidence of diagnosis.
Genetic screening does not replace the need for regular clinical screenings for any of the
conditions or analytes mentioned in this report.
DISCLAIMER
The information contained within this report is intended for informational purposes only. Do
not alter any regularly scheduled health screenings due to the findings of this genetic analysis.
Disclaimer | Page 46
In a low-carb diet, fats and proteins each constitute 30% of the daily intake, while carbohydrates account for 40%. Comparatively, in a balanced diet, fats constitute 25% and proteins also 25%, with carbohydrates making up 50%. This suggests a greater reliance on proteins and fats for energy in a low-carb diet, potentially altering metabolic processes and nutrient absorption .
Genetic predispositions, such as the presence of certain variants in the GC gene, can influence vitamin D levels by affecting the protein that binds vitamin D, reducing its circulation in the body. To maintain adequate levels, individuals should increase their intake of vitamin D-rich foods like fatty fish and ensure regular, moderate sun exposure to help the skin synthesize vitamin D .
Vitamin B12 deficiency can occur due to genetic factors, such as a polymorphism in the FUT2 gene, dietary restrictions like veganism, and health conditions affecting absorption, like digestive disorders. Those with two copies of the "G" allele at position rs602662 are at higher risk, as well as vegans, vegetarians, and the elderly. Deficiency symptoms include fatigue, weakness, and neurological issues .
Foods rich in vitamin E, such as cooking oils (e.g., olive oil), nuts (e.g., almonds), and spreads (e.g., natural peanut butter), are recommended to increase intake. Some individuals may need more dietary vitamin E due to genetic differences that affect absorption, like those associated with the SNP rs12272004, which can result in lower plasma levels of ɑ-tocopherol .
A balanced diet can be achieved by using the hand as a guide to measure food portions instead of counting calories. One should include lean protein and vegetables with each meal or snack. Most meals should also feature smart carbohydrates like whole food carbs rich in vitamins, minerals, and fiber, and healthy fats from whole food sources. Women's portions typically include a palm of protein, a fist of vegetables, a cupped handful of smart carbs, and a thumb of fat, while men's portions are double these amounts .
The Mediterranean diet supports heart health by emphasizing the consumption of fruits, vegetables, fish, and healthy fats, while minimizing the intake of processed foods and unhealthy fats. This diet is rich in monounsaturated fats and omega-3 fatty acids, which help reduce inflammation and improve cardiovascular health .
Vitamin C is essential for collagen synthesis, wound healing, neurotransmitter production, and acts as an antioxidant. It's crucial for absorbing nonheme iron and regenerating other antioxidants like vitamin E. Since the body can't produce vitamin C, regular intake from fruits and vegetables is vital to prevent deficiencies linked to muscle pain, fatigue, and slow wound healing .
Using one's hand as a portion guide simplifies dietary planning by providing a personalized, flexible method to estimate food portions. It helps ensure balanced nutrient intake without focusing on calorie counting and can be adjusted to individual dietary needs and goals .
Smart carbohydrates provide dietary benefits such as improved satiety, blood sugar control, and increased fiber intake, whereas not-so-smart carbohydrates can lead to increased blood sugar levels and insulin resistance. Smart carbs include fruits, starchy tubers, and whole grains, while not-so-smart carbs can be found in items like white bread, packaged oats, and sugary drinks .
Trans fats should be minimized or avoided because they increase the risk of coronary heart disease, cancer, and other chronic health conditions. These fats are artificially produced to convert liquid oils into solids, improving food shelf life and mouthfeel. They are often found in margarine, baked goods, and processed foods, and can be identified by partially hydrogenated oils on ingredient labels .