Cross-Specialization Training of Grades 7-10 Science Teachers
on their non-major Science Subject
October 15-20, 2018
Grade 10 Activity Sheet on Protein Synthesis
Activity 3: Nucleic Acid Segment
Objective
Apply the concept of protein synthesis through the amino acids coded for the
mRNA codon using the genetic code.
Materials
Pen
Crayons
Activity sheet: Decoding DNA segment
Procedure
1. Study the given scenario (see attached activity) and study the profile of the suspects
and additional information.
2. Using your knowledge about DNA and RNA base-pairing, decode the DNA sample in
order to identify the sequence of amino acids. Use the amino acid identifier chart as
your reference.
3. Compare the sequence of amino acids (proteins) to the profile of the suspects and
additional information given in order to determine the corresponding traits.
4. Name the culprit using the data or information you got.
5. Using the pencil and crayons make a cartographic sketch of the suspect.
Q1. What amino acids sequences did you get upon decoding the genes?
nose hair :
shape of eyes :
lips :
ear attachment:
type of hair :
Q2. What are the traits of the culprit based on your data?
Q3. Who among the suspects matches with the sequence of amino acids (proteins)
you got?
Q4. Draw the possible appearance of the culprit.
Adapted from the presentation of Dr. Catherine Genievie Lagunzad, during the ACED Training of Public School
Teachers
Cross-Specialization Training of Grades 7-10 Science Teachers
on their non-major Science Subject
October 15-20, 2018
Decoding DNA
Segment
An intruder razed the science laboratory of a Junior High School. The school
is in chaos. The school administrators and teachers demanded to know the
culprit. They have to identify the culprit and do it fast. They had three
suspects namely Rudy Tee, Von Go and Rambo Tan. As a forensic expert, your
mission is to identify the intruder using the profile of the suspects and other
information taken from the laboratory:
THE PROFILE OF THE SUSPECTS
Rudy Tee
Flunked physics class full lips
three times attached ear lobe
with long nose hair, straight hair
oval eyes
Von Go
His investigative project short nose hair
is about the potential
chinky eyes
applications of nuclear
full lips
fusion in generating
free earlobe
energy.
curly hair
Rambo Tan
Suspended for a week by
the Disciplinary
Committee for repeated
tardiness.
short nose hair
oval eyes
harelip
attached earlobe
wavy hair
Adapted from the presentation of Dr. Catherine Genievie Lagunzad, during the ACED Training of Public School
Teachers
Cross-Specialization Training of Grades 7-10 Science Teachers
on their non-major Science Subject
October 15-20, 2018
Additional Information: Below are the specific amino acid sequence for specific trait.
1. Nose hair
Short : phe-lys
Long : leu-lys
2. Shape of Eyes
oval : val-ala-ala
chinky : val-ala-val
3. Lip
s
Full lips : phe- glu-ala
Harelip : phe-lys-ala
4. Ear attachment
Free earlobe : thre- tyr-ser
Attached : leu-arg-gly
5. Type of hair
Straight : lys-glu
Wavy : phe-ala
Curly : glu-phe
THE DNA CODE OF THE SUSPECT
A fresh DNA sample was obtained from the laboratory; believe to have been
left by the suspect. Using the DNA sequencer the following nucleotide sequence was
obtained:
SUSPECT: TAC-AAA-TTT-ATC-TAC-AAA-CTT-CGT-ATC-TAC-CAT-CGT-CAT-ATT-TAC-TGG-
ATA-TCG-ATC-TAC-CTT-AAA-ATC
Complementary base pairs: DNA is represented by nitrogen bases that are read
in groups of threes. To decode, use the DNA as a blueprint to produce mRNA. Then
use the mRNA as blueprint to produce the linear sequence of tRNA. A specific
nitrogen base in the DNA pairs up with a specific nitrogen base in the mRNA, and a
specific nitrogen base in the mRNA pairs up with a specific nitrogen base in the
tRNA.
Breaking the Code: Complete the data table below.
DNA triplet code mRNA tRNA Amino acid
TAC
AAA
TTT
ATC
3
Cross-Specialization Training of Grades 7-10 Science Teachers
on their non-major Science Subject
October 15-20, 2018
TAC
AAA
CTT
CGT
ATC
TAC
CAT
CGT
CAT
ATT
TAC
TGG
ATA
TCG
ATC
TAC
CTT
AAA
ATC
Characteristics and traits of the suspect based on the DNA code.
1. Nose hair:
2. Eyes:
3. Lips:
4. Ear attachment:
5. Type of hair :
Name and cartographic sketch of the suspect
4
Cross-Specialization Training of Grades 7-10 Science Teachers
on their non-major Science Subject
October 15-20, 2018
DNA triplet code mRNA tRNA Amino acid
TAC
AAA
TTT
ATC
TAC
AAA
CTT
CGT
ATC
TAC
CAT
CGT
CAT
ATT
TAC
TGG
ATA
TCG
ATC
TAC
CTT
AAA
ATC