CHAPTER
ENVIRONMENTAL AND
NUTRITIONAL DISORDERS 8
OBESITY
(8.01)
I
Exams
tniversity
questions
hort and pathogenesis of Obesity
Sho
D8scribe etiology of obesity
for assessment
Parameters (BMI)
1.
ite
Body mass index
Overview (00:00:48)
assessment of obesity (00:01:43)
Introduction
erameters for
(00:13:29)
Etiology (00:15:23)
Pathogenesis (00:16:35)
Effects of Obesity
Introduction
risk
Excess of adipose tissue that imparts health
excess over ideal weight for age, sex and heiaht is considered a health risk.
.A body weight of 20%
Parameters for assessment of obesity
1. BMI (Quetlets index)
2. Broca's index
3. Lorentz's formula
4. Corpulence index (HT. independent)
5. Skin fold thickness
1. BMI (Quetlets index)
Internationally accepted method of assessment of obesity
Most widely used method to gauge obesity
BMI
Wt (Kg)
(Quetlets index) =
Ht² (m)
• A cut-off BMI value of 30 is used for obesity in both men and women.
m, DR. PRIYANKA SACHDEV
Classificatlon BMI(GIobal)
Underweight <18.5
Grade I
17.00-18.49
Grade Il 16.00-16.99
Grade Im < 16
Normal range 18.50-24.99
Overweight >25.00
Preobese 25.00-29.99
Obesity- | 30.00-34.99
Obesity 35.00-39.99
Obesity- II (Morbid) >40.00
2. Broca's index = Ht - 100 =
ldeal wt
3. Lorentz's formula = Ht (cm)-150
Ht(cm) -100
2 (women) or 4 (men)
Actual Wt
4. Corpulence index (HT. independent) = < 1.2
Desirable Wt
5. Skin fold thickness
Noninvasive method for body assessment fat
4 sites - biceps / midtriceps / Subscapular & suprailiac region
Measured by - Herpenden skin calliper
Single best measurement - Midtriceps
-
Obesity Cut off
> 18mm (boys)
> 32mm (girls)
Etiology
Obesity results when caloric intake exceeds utilisation.
Imbalance occur in following situations >
1. Inadequate pushing of oneself away from dining table causing overeating.
2. Insufficient pushing of oneself out of chair leading to inactivity and sedentary life style.
3. Genetic predisposition to develop obesity.
4. Diets derived from carbohydrates and fats
5. Secondary obesity underlying diseases hypothyroidism, Cushing's disease, insulinoma and
hypothalamic disorders.
PAGE 160 | ENVIRONMENTAL AND NUTRITIONAL DISORDERS
PATHOLoGY PROF
BUSTER m)
pathogenesis
Specific/Over nutrition
Proinflammatory
cytokines
leptin
Inflammation
Hyperleptinemia
Obesity
Central and Peripheral
Leptin resistances
Impaired Impaired gucose
nutrient Food intake
T
and lipid
absorption metabolism
Effects Of Obesity
Hyperìnsulinaemia
9 Type 2 diabetes mellitus -Stroke
Hypertension
3. Hyperlipoproteinaemia Hypoventilatlon syndrome
4,
5. Atherosclerosis Poronary atery ises
e
Nonalcoholic fatty liver disease (NAFLD)
Cholelithiasis Hypertesion
7.
HVDoventilation Fatty lver
syndrome (Pickwickian syndrome) Type 2 diabetes
9. Osteoarthritis
10. Cancer CholeGthiass
Atherosdeross,
Hypoventilation syndrome byperipidaemia
(Pickwickian syndrome)
Obese individuals
Osteoatitts
Carbon dioxide retention and hypoxia
Polycythaemia and Hypersomnolence
([Link] was a character, the fat boy, in Charles Dickens' Pickwick Papers Term Pickwickian
syndrome was first used by Sir William Osler for sleep apnea syndrome).
ENVIRONMENTAL AND NUTRITIONAL DISORDERS | PAGE 161