Question Choices

1. Analyze and select the factor that Zeta potential measures the electrostatic
governs the degree of repulsion in repulsion between particles due to their
systems containing dispersed charge.
particles.
A. Entropy
B. Enthalpy
C. Nernst potential
D. Zeta potential
2. An arbitrary scale of values by means
of which it is possible to establish a
range of optimum efficiency for each
class of surfactant
A. Zeta potential
B. Nernst potential
C. HLB
D. Spreading coefficient
3. Classify acacia as a pharmaceutical
excipient
A. Vehicle
B. Binder
C. Humectant
D. Suspending agent
4. Identify the law associated with Boyle’s Constant temperature,
sedimentation: law Pressure is inversely
A. Stokes law proportional to the volume
B. Boyle’s law Fick’s Law Passive diffusion
C. Fick’s law Arrhenius reaction rates and shelf-life
D. Arrhenius Law law
5. Select the principal category to which
Glycerin, honey, glucose syrup, egg
yolk, and sugar alcohols belong.
A. Humectant
B. Suppository base
C. Stiffening agent
D. Tablet binder
6. This is used for relating the effect of Le Chatelier’s “stress” such as
the least number of independent principle concentration and
variables (e.g. temperature, pressure pressure affect the
and concentration) upon the various equilibrium
phases that can exist in an equilibrium Raoult’s Law Governs vapor
system containing a given number of pressure lowering
components?
Phase diagram Graphical plots that
A. Le Chatelier’s principle
show the relationships
B. Gibb’s phase rule
between the various
C. Phase diagram
D. Raoult’s Law phases
7. It is defined as the number of moles Molarity # of moles of solute per
of solute dissolved in 1000 grams of liter of solution
solvent. Normality # of gram equivalent
A. Molarity weight per liter of solution
B. Molality Formality # of gram-formula mass
C. Normality of ionic solute per liter of
D. Formality solution
8. Ethylene glycol is a common ΔTf = ikfm
automobile antifreeze. Calculate the
freezing point of a solution *Calculate the molality (moles of solute per
containing 651 grams of this Kg of solvent)
substance in 2505 grams of water.
The molar mass of ethylene m = 651/62.01/2.505 = 4.191 m
glycol=62.01, Kf=1.86C/molal ΔTf = (1)( 1.86OC/molaI)(4.191m)
A. 7.8 ΔTf =7.8OC (This is the freezing point
B. -7.8 depression)
C. -10.32
D. 10.32 To calculate the freezing point: 0OC – 7.8OC
= -7.8OC
9. The movement of water across a Diffusion Movement of particles
semipermeable membrane from a (solute) from high to low
region of lower to higher concentration
concentration: Osmosis Movement of solvent from
A. solubility low to high solute
B. osmosis concentration across a
C. diffusion semipermeable
D. permeability membrane
10. Upon accidental injection of an Hypotonic Swell, then burst
unknown solution to a patient, Hypertonic Crenation or
hemolysis resulted. Which of the shrinkage
following solutions may have been Isotonic None
administered?
A. isotonic
B. hypertonic
C. hypotonic
D. tonic
11. The USP method of adjusting the Formula: wt x E x 111.1
isotonicity of solutions:
A. White Vincent Method
B. Sprowls Method
C. Cryoscopic Method
D. E-value Method
12. How many milligrams of sodium Step 1: How much must be added to the
chloride is required to prepare 30 mL drugs freezing point depression to
of a 1% solution of dibucaine complete the 0.052OC?
hydrochloride isotonic with tears?
The freezing point depression of 1% 0.08OC + _x = 0.52OC
dibucaine HCl is 0.08 x = 0.44OC
A. 228 mg
B. 520 mg Step 2: Ratio and proportion
C. 150 mg
D. 112 mg 0.9% 0.52OC
------- = ----------
(x) % 0.44OC
x = 0.762%, interpret then calculate the
amount in a 30-mL solution
0.762g
---------- x 30mL = 0.228g or 228 mg
100 mL
13. Which of the following is a
physicochemical problem
encountered in suspensions?
A. syneresis
B. creaming
C. bleeding
D. caking
14. A sample powder was poured through Θ =tan – (2h/d)
a funnel and formed a cone 3.3 cm
high and 9 cm in diameter. What is Θ = tan – (6.6/9)
the angle of repose? Θ = 36.25O
A. 0.73 degrees
B. 36.25 degrees
C. 10.39 degrees
D. 69.86 degrees
15. What phenomenon happens when
menthol and camphor are combined
resulting in liquefaction of the
mixture?
A. Deliquescence
B. Efflorescence
C. Hygroscopicity
D. Eutexia
16. You are asked to prepare a buffer Noyes-Whitney Dissolution
solution. Which of the following can you Van slyke’s Buffer capacity
use for the calculations of the molar equation
quantities of the major components?
A. Henderson-Hasselbalch Equation
B. Noyes-Whitney Equation
C. Fick’s Law
D. van Slyke’s Equation
17. Which of the following exists in Sodium chloride Cubic
tetragonal form? Urea Tetragonal
A. boric acid Sucrose Monoclinic
B. sodium chloride Boric acid Triclinic
C. sucrose
D. urea
18. This refers to the force acting
between two immiscible liquid
phases such as those in emulsions:
A. adhesion
B. surface tension
C. cohesion
D. interfacial tension
19. Most drugs follow what reaction
kinetics?
A. zero-order
B. third-order
C. first-order
D. second-order
20. The E value refers to the:
A. gram of NaCl equivalent to 1 gram of
a drug
B. freezing depression of a 1% solution
of a given drug
C. isotonic freezing point depression
D. weight of drug equivalent to 1 gram
of NaCl
21. Analyze which sterilization method
allows the sterilization of packaged
finished products that are ready for
shipment because sterilizing
material permeates sealed plastic
films and cartons.
A. Dry heat
B. Ionizing radiation
C. Gas sterilization
D. Membrane filtration
22. Calculate the approximate E value of E = 17 x Liso/MW
boric acid. (MW 61.84, Liso 1.8)
A. 0.03 E = 17 x (1.8/61.84 )
B. 0.5 E= 0.50
C. 0.8
D. 0.7

23. Select the Non-Newtonian liquids

A. Virgin coconut oil, Gold Colloid
B. Tobramycin, Chloramphenicol
Palmitate Suspension
C. Olive Oil, Chloroform
D. Ethyl alcohol, Mayonnaise
24. Identify the weak intermolecular
forces, example of which are the
Keesom-Debye, and London forces.
A. Ion-dipole, ion-induced dipole forces
B. Van der Waals forces
C. Hydrogen bonds
D. Repulsive and attractive forces
25. Select the concept that explains the Law Defines
thermodynamics state of a perfect 0th Temperature equilibrium
crystal at absolute zero. 1st Conservation of energy
A. 3rd Law of Thermodynamics 2nd Entropy
B. 2nd Law of Thermodynamics 3rd Numerical definition of
C. 1st Law of Thermodynamics entropy
D. 1st, 2nd, 3rd Laws of Thermodynamics
26. Identify the property of particles,
which is determined by allowing the
powder to flow through a funnel and
fall free onto a surface, then
measuring the height and diameter
of the cone, results of which are used
to calculate this particular property.
A. Bulk volume
B. Angle of repose
C. Bulkiness
D. Porosity
27. Select the oral dosage form, which
contains one or more active
ingredients that are unstable in the
water phase but stabilized in oil-in-
water dispersions; either or both
phases may contain dissolved solids.
A. Oral emulsion
B. Elixir
C. Syrup
D. Oral drops
28. The following are advantages of
transdermal drug delivery systems,
EXCEPT _______.
A. NOT suitable for all drugs
B. Avoid the risk and inconvenience of
parenteral therapy
C. Avoid the first-pass effect
D. Provides the capacity for multiday
therapy with a single application,
thereby improving patient
compliance
29. Determine the effect of overwetting
to resulting granules.
A. Granules will be dry
B. Granules will be hard
C. Granules will be soft
D. Granules will be soggy
30. Identify the method of preparing
powders that consists of enclosing
the powder enclosed in a container,
which rotates and mixes the powder
ingredients.
A. Sifting
B. Tumbling
C. Mechanical mixing
D. Trituration
31. Determine the role of lactose,
cellulose, kaolin, mannitol in a tablet
formation.
A. Lubricants
B. Diluents
C. Glidants
D. Binders
32. Classify tablets that are prepared by
compressing granular materials that
have the capacity to release gas
when in contact with water.
A. Enteric-coated tablets
B. Buccal tablets
C. Effervescent tablets
D. Multiple compressed tablets
33. Protein substances, such as gelatin,
egg yolk, and casein produce
____________ emulsions
A. w/o emulsions
B. o/w emulsions
C. Both A and B
D. None of these

34. Find the incorrect statement about Beta = most stable (preferred)
Theobroma Oil. Alpha = metastable
Gamma=least stable
A. The beta crystal is its stable form
with a melting point approaching 35
degrees C.
B. Requires a fusion temperature of 40-
50OC to prevent a change in crystal
form and melting point.
C. It is a naturally occurring alkaloid.
D. The alpha form is metastable with a
melting point of 30 degrees C.
35. Slugging is one of the steps in
A. Molding
B. Direct compression
C. Sugar coating
D. Dry granulation
36. The upward movement of dispersed
droplets in an emulsion system is
A. Sedimentation
B. Flocculation
C. Creaming
D. Cracking
37. Percolation may be used to prepare
A. Ointments
B. Solutions
C. Syrups
D. Suspensions
38. Parabens are used in syrups as
A. Preservatives
B. Thickener
C. Sweetener
D. Buffer
39. According to USP standards, a
refrigerator can be used to store
pharmaceuticals that specify storage
in a:
A. Dark place
B. Cold place
C. Cool place
D. Controlled RT
40. Hydrous woolfat is a/an
A. Hydrocarbon Ointment Base
B. Absorption Ointment Base
C. Water – Removable Ointment Base
D. Water – Soluble Ointment Base

41. A powder preparation used with a

toothbrush to clean the teeth is
A. Dusting
B. Dentifrice
C. Insufflation
D. Douche
42. Collodion is made flexible by the Cotton + HNO3 + H2SO4 = Pyroxylin
addition of Pyroxylin + alcohol + ether = collodion
A. Olive oil Collodion + camphor + castor oil = flexible
B. Castor oil collodion
C. Gelatin
D. Camphor
43. Syrups may be prepared by the
following, except
A. Agitation without heat
B. Percolation
C. Solution with Heat
D. Fusion
44. These are liquid preparations
containing suspended and insoluble
substances
A. Suspension
B. Emulsion
C. Solution
D. Syrup
45. Role of Potassium Iodide in the
preparation of Lugol’s solution
A. Cosolvent
B. Solubilizing agent
C. Preservative
D. Active ingredient
46. Method of extraction where a drug is Maceration Soak
soaked for 3 days with frequent Percolation Latin: colo = filter,
agitation strain and purify
A. Maceration Digestion Gentle heat
B. Percolation Infusion Hot or cold
C. Digestion menstruum
D. Infusion
47. These are clear saturated aqueous
solutions of volatile oils that contain
no preservatives
A. Enemas
B. Oleovitamins
C. Aromatic waters
D. Spirits
48. These are reversible instabilities of
an emulsion, except
A. Flocculation
B. Sedimentation
C. Creaming
D. Coalescence
49. Emulsifying agents from vegetable
sources, except
A. Acacia
B. Casein
C. Chondrus
D. Pectin
50. The pharmaceutical agent used to
prevent rancidity of the oil phase in
an emulsion
A. Antimicrobial agent
B. Antioxidant
C. Emulsifying agent
D. Vehicle
51. An agent that “glue” powders
together and cause them to form
granules is the
A. Glidant
B. Diluent
C. Disintegrant
D. Binder
52. What is RA 8203?
A. The Dangerous Drugs Act of 1972
B. Generic Act of 1988
C. Food, Drugs and Devices, and
Cosmetics Act
D. Special Law on Counterfeit Drugs
53. Which of the following
pharmaceutical preparations is
classified as a Newtonian substance?
A. Suspension
B. Solution
C. Ointment
D. Emulsion
54. Which kind of water is obtained by
distillation, ion-exchange treatment,
reverse osmosis, or any other
suitable process; contains no added
substance, and NOT used in
preparations intended for parenteral
administration
A. Sterile Water for Injection
B. Purified Water
C. Water for injection
D. Bacteriostatic Water for Injection
55. Wholesalers/Distributors of DD or
DDP or controlled chemicals used in
the drug preparation(s) and/or their
preparation(s)
A. S-1
B. S-4
C. S-5D
D. S-5
56. An oral liquid that is prepared to be
administered in small quantities
with the help of a suitable
measuring device
A. Linctus
B. Elixir
C. Syrup
D. Oral drop
57. What are the important
considerations in the choice of
excipients?
I. Cross-contamination
II. Compatibility with the active
drug
III. Effect on efficacy
IV. Cost of formulation
A. I, II, IV
B. II, III, IV
C. I, II, III
D. I, III, IV
58. Which drugs have local effects?
I. Povidone-iodine topical
solution
II. Cetaphil moisturizing lotion
III. Petroleum jelly
IV. Amoxicillin capsule
A. II, III, IV
B. I, IV
C. III, IV
D. I, II, II
59. Select the pair/s that is/are correctly
matched.
I. Peppermint water –
Hydroalcoholic
II. Aromatic elixir – Hydroalcoholic
III. Compound Cardamon Tincture –
Alcoholic
IV. Simple Syrup - Aqueous
V. Orange Flower Water – Alcoholic
A. I, II, III
B. II, III, IV
C. I, IV, V
D. I, V
60. What are the methods of preparing
ointments?
A. fission and incorporation
B. fission and fusion
C. fusion and tumbling
D. fusion and incorporation
61. What is the % NaCl content of NSS?
A. 0.009%
B. 0.9%
C. 9%
D. 0.009%
62. The excipient that prevents the
decomposition of pharmaceutical
products
A. Preservatives
B. Colorants
C. Surfactants
D. Disintegrants
63. Which of the following is not a
colligative property?
A. Freezing point depression
B. Boiling point elevation
C. Vapor pressure elevation
D. Osmotic pressure
64. Classify the given organogel: Lard
A. Hydrocarbon-type
B. Animal and vegetable fat
C. Soap-based grease
D. Hydrophilic organogel
65. What is the mechanism of action of
benzoic acid as a preservative?
A. Protein denaturation
B. Cell membrane lysis
C. Oxidation
D. Cell wall synthesis inhibition
66. An oral liquid that contains one or
more active ingredients dissolved in a
suitable base
A. Solution
B. Suspension
C. Emulsion
D. Ointment
67. Which of the following forms a
water-in-oil type of emulsion?
A. Carbohydrates materials
B. Protein substances
C. Vanishing cream
D. Cholesterol derivatives
68. The liquid or gas being absorbed
penetrates the capillary spaces of
the absorbing medium:
A. Adsorption
B. Absorption
C. A and B
D. NOTA
69. It is an excellent vehicle for saline
substances because of its colloidal
properties, sweet flavor, and lingering
taste of licorice.
A. Aromatic Eriodictyon syrup
B. Fruit syrups
C. Glycyrrhiza syrup
D. Acacia syrup
70. Sterile water for injection containing
one or more suitable antimicrobial
agents
A. Purified water
B. Water for injection
C. Bacteriostatic water for injection
D. NOTA
71. Assigned HLB of surfactants with
detergent activity:
A. 1-3
B. 13-16
C. 7-9
D. 15-20

72. The following are true regarding the

HLB system except:
A. Although the numbers have been
assigned up to about 40, the usual
range is between 1 and 20.
B. Materials that are highly polar or
hydrophilic have been assigned
higher numbers than materials that
are less polar and more lipophilic.
C. Generally, surface-active agents
having an assigned HLB value of 3 to
6 are greatly lipophilic and produce
o/w emulsions
D. NOTA
73. The following statements are false
regarding the HLB system, except:
A. In the HLB system, in addition to the
emulsifying agents, values are
assigned to oils and oil-like
substances.
B. One selects emulsifying agents
having the opposite HLB value as the
oleaginous phase of the intended
emulsion.
C. Two or more emulsifiers cannot be
combined in preparing emulsions
D. NOTA
74. What law or issuance contains the
requirements for Good
Manufacturing Practice applied to
premises, equipment, personnel,
products, and warehouse?
A. FDA Advisory
B. FDA memorandum Circular
C. RA 7432
D. Administrative Order from DOH
75. QC test for USP type II glass:
A. Powder glass test
B. Water attack test
C. Both A and B
d. NOTA
76. Which of the following are objectives
of RA 10918?
I. Standardization and regulation of
pharmacy education;
II. Administration of licensure
examination, registration, and
licensing of pharmacists;
III. Supervision, control, and
regulation of the practice of
pharmacy in the Philippines;
IV. Development and enhancement
of professional competence of
pharmacists through continuing
professional development,
research, and other related
activities; and
 V. Integration of the pharmacy
profession.
A. I only
B. II and III
C. II, III, IV, and V
D. I, II, III, IV, and V
77. Applicable S-license for laboratory
analysis or technical research using
DP/DDPs and/or DPs
A. S-4
B. S-5I
C. S-5E
D. S-6
78. A pharmacist working in a Category A
establishment may be allowed to
simultaneously work or render
pharmacy services in Category B
establishments.
A. True
B. False
C. Doubtful
D. None of these
79. E-value method
A. Method I
B. Method II
C. A and B
D. NOTA
80. USP method for particle size analysis
A. optical microscopy
B. Sieving method
C. Screening
D. Sieve method and screening
81. Force of attraction that accounts for
many of the unusual properties of
water including its high dielectric
constant, abnormally low vapor
pressure, and high boiling point.
A. Ion-dipole and Ion-induced dipole
forces
B. Hydrogen bond
C. Van der Waals Forces
D. NOTA
82. Particle size analysis method used
for evaluation of suspensions,
emulsions and determination of
molecular weight of polymers.
A. Sieving method
B. Sedimentation
C. A and B
D. NOTA
83. Irregular, zigzag pattern movement
of colloids
A. Brownian motion
B. Diffusion
C. Sedimentation
D. NOTA
84. Which of the following is incorrectly
paired?
A. Ubbelohde: Density measurement
B. Pycnometer: specific gravity
measurement
C. Polarimeter: optical activity
measurement
D. Optical microscopy: Particle size
measurement
85. Classify the ointment base: PEG, NF
A. Oleaginous base
B. Absorption base
C. Water removable base
D. Water soluble base
86. Classify the ointment base: Yellow
ointment
A. Oleaginous base
B. Absorption base
C. Water removable base
D. Water soluble base
87. Film cracking type I is caused:
a. Over-drying
b. Excessive moisture uptake into tablet
cores
c. A and B
d. NOTA
88. Classify the tableting problem:
Lamination
a. Process related
b. Excipient related
c. Machine related
d. More than 1 factor
89. Solid gels with no solvent Aerogel Liquid phase of a gel is
concentration, which are formed replaced by a gas, with
after evaporation of the solvent in a slight gel shrinkage
hydrogel or an organogel by drying Xerogel Liquid phase of a gel is
at ambient conditions. removed by evaporation
A. Xerogels Cryogel Gel that is formed by freeze-
B. Aerogels drying a sol
C. Cryogels
D. None of these
90. Which of the following preservatives CI: neonates
is linked to Gasping syndrome?
A. Ethyl alcohol
B. Benzyl alcohol
C. Sodium borate
D. Benzalkonium chloride
91. Refer to persons who assist the Pharmacists Valid COR and PRC ID, do the
pharmacists in different aspects of patient counseling
pharmacy operation based on Pharmacy Assist in compounding and
established SOP and processes, with technicians dispensing of drugs under
a minimum degree of independence the supervision of RPh
Pharmacy Assist the RPh in pharmacy
or decision making and may have
assistants operation, with minimal
supervised interaction with patients.
degree of independence
A. Pharmacy aides Pharmacy Assist the RPh in pharmacy
B. Pharmacy assistant aides operation, with very minimal
C. Pharmacy technician degree of independence and
D. NOTA without direct interation
with patients
92. An independent advisory body
created with the overall role of
providing guidance to the DOH and
PhilHealth on the coverage of health
interventions and technologies to be
funded by the government
A. FDA
B. IATF
C. HTAC
D. NOTA
93. Ethylenediaminetetraacetic acid is a
A. Tridentate
B. Monodentate
C. Bidentate
Hexadentate
94. Classify compounds that are of low
solubility and high permeability, such
that their bioavailability is limited by
their solvation rate.
A. BCS Class I
B. BCS Class IV
C. BCS Class III
D. BCS Class II
95. Select the range of sodium ion
concentration in a TPN preparation
A. 5-10 mEq
B. 100-120 mEq
C. 40-60 mEq
D. 8-16 mEq
96. The Expanded Senior Citizens Act of
2010 is______.
A. RA 11223
B. RA 6675
C. RA 9502
D. RA 9994
97. Where do senior citizens get their
senior citizen card?
A. Office of the Provincial Governor
B. Office of the Mayor
C. Office of the Provincial/Municipal/
City Treasurer
D. Office of Senior Citizen Affairs
98. Select the components of an
erroneous prescription.
A. When only the brand name is
written in the prescription
B. When the generic name is NOT
legible, and the brand name is
legible
C. When the brand name and generic
name are NOT legible
D. When the generic name is
enclosed within a parenthesis,
and the brand name is NOT
99. Identify RA 3720
A. Newborn Screening Act
B. Food, Drug and Cosmetic Act
C. Pharmacy Act
D. Expanded Senior Citizens Act
100. Select the Act that as promulgated,
repealing Dangerous Drug Act
A. Comprehensive Dangerous Drug Act
B. Dangerous Medicines Act
C. Universal Health Care Act
D. Pharmacy Act