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Systemic Lupus Erythematosus Overview

The document outlines the symptoms and complications associated with systemic lupus erythematosus, including butterfly rash, urinary retention, and chest pain. It emphasizes the importance of treatment to prevent severe outcomes such as multi-organ failure and death, while also listing predisposing and precipitating factors. Additionally, it describes the immune response mechanisms leading to the disease, highlighting the role of sun exposure and genetic susceptibility.

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Ram Ram
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3 views2 pages

Systemic Lupus Erythematosus Overview

The document outlines the symptoms and complications associated with systemic lupus erythematosus, including butterfly rash, urinary retention, and chest pain. It emphasizes the importance of treatment to prevent severe outcomes such as multi-organ failure and death, while also listing predisposing and precipitating factors. Additionally, it describes the immune response mechanisms leading to the disease, highlighting the role of sun exposure and genetic susceptibility.

Uploaded by

Ram Ram
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

SKIN KIDNEY HEART (SEROSA)

BUTTERFLY RASH URINARY RETENTION CHEST PAIN

IF TREATED: SYSTEMIC LUPUS IF LEFT UNTREATED:


MEDICATIONS ERYTHEMATOSUS - PHOTOSENSITIVITY
WEAR SUNSCREEN - ULCER
REGULAR CHECK-UP - PLEURITIS
- PERICARDITIS
- ARTHRITIS
- PROTEINURIA
REDUCE RISK OF
COMPLICATIONS
- ANTIPHOSPHOLIPID
SYNDROME
RECOVERY - PSYCHOSIS
- ANEMIA
- THROMBOCYTOPENIA
- LEUKOPENIA
- SEIZURES

MULTI-ORGAN FAILURE
CARDIAC ARREST

DEATH
PREDISPOSING FACTORS PRECIPITATING FACTORS
AGE SUN EXPOSURE
INFECTIONS
GENDER HORMONAL CHANGES (PUBERTY)
GENETICS ENVIRONMENT

SUSCEPTIBLE GENES EXPOSED TO UV-


RAYS SUNLIGHT

SUNBURN LEADS TO SEVERE CELL BREAKING DOWN OF IMMUNE SYSTEM MISTAKENLY B-CELLS DETECTS PRODUCES MORE
DAMAGE WHICH RESULTED TO APOPTIC BODIES INCLUDING IDENTIFY APOPTIC BODIES AS NUCLEAR ANTIGENS ANTINUCLEAR
APOPTOSIS (PROGRAMMED CELL DEATH) THE PART OF NUCLEUS NUCLEAR ANTIGENS ANTIBODIES

ENTERS THE BLOOD FORMS ANTIGEN- ANTINUCLEAR


STREAM AND TRAVELS TO ANTIBODY COMPLEX ANTIBODIES BINDS TO
INFLAMMATION
DIFFERENT ORGANS AND NUCELAR ANTIGENS
TISSUES IN THE BODY

SYMPTOMS

SKIN KIDNEY HEART

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