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HKDSE Biology: Key Biological Molecules

The document outlines the chemical constituents of organisms, categorizing them into inorganic substances like water and minerals, and organic substances such as carbohydrates, lipids, proteins, and nucleic acids. It details the functions and classifications of these biomolecules, including their roles in metabolism and structure, as well as biochemical tests for their presence. Additionally, it compares DNA and RNA, highlighting their importance in heredity and protein synthesis.

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0% found this document useful (0 votes)
16 views6 pages

HKDSE Biology: Key Biological Molecules

The document outlines the chemical constituents of organisms, categorizing them into inorganic substances like water and minerals, and organic substances such as carbohydrates, lipids, proteins, and nucleic acids. It details the functions and classifications of these biomolecules, including their roles in metabolism and structure, as well as biochemical tests for their presence. Additionally, it compares DNA and RNA, highlighting their importance in heredity and protein synthesis.

Uploaded by

try58s7x6q
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

HKDSE BIOLOGY: Connecting Concepts Revision notes

2 Molecules of life

2.1 Chemical constituents of organisms


1. Organisms are made up of chemical substances which can be divided
into two groups:
• inorganic substances (e.g. water and minerals)
• organic substances or biomolecules (e.g. carbohydrates, lipids,
proteins and nucleic acids)

2.2 Water
2. Water is important to life as it serves the following important
functions in organisms, as a:
• solvent, transport medium and the medium in which chemical
reactions take place
• reactant in some metabolic reactions
• cooling agent
• temperature buffer
• supporting agent

2.3 Minerals
3. Minerals are required in small amounts only, but are essential to the
normal functioning of organisms.

4. Some important inorganic ions include:


• nitrate, which is needed for making proteins, nucleic acids and
chlorophyll
• magnesium, which is needed for forming chlorophyll in plants and
is a component of bones and teeth

© Aristo Educational Press Ltd. 2-1


HKDSE BIOLOGY: Connecting Concepts Revision notes

• calcium, which is a major component of bones, teeth and shells


• iron, which is needed for forming haemoglobin and in plants for
forming chlorophyll

5. Carbohydrates are organic substances made up of carbon, hydrogen


and oxygen. They have a general formula of Cx(H2O)y.

6. Carbohydrates can be classified into three types according to their


complexity:
Characteristics Examples
Monosaccharides • Simplest forms of Glucose, fructose
carbohydrates and galactose
• Soluble in water and taste
sweet
• All are reducing sugars
Disaccharides • Formed by condensation of Maltose, sucrose
two monosaccharide and lactose
molecules with the removal of
a water molecule
• Soluble in water and taste
sweet
• Most are reducing sugars,
except sucrose
Polysaccharides • Complex carbohydrates Starch, glycogen
formed by condensation of a and cellulose
large number of
monosaccharide molecules
• Insoluble in water

© Aristo Educational Press Ltd. 2-2


HKDSE BIOLOGY: Connecting Concepts Revision notes

7. Carbohydrates have the following functions in organisms:


• Glucose can be directly broken down in cells during respiration to
release energy.
• Starch and glycogen are storage forms of carbohydrates in plants
and animals respectively.
• Cellulose is the main component of plant cell walls.

8. Biochemical tests for carbohydrates:


Substance Test Positive result
Glucose Using glucose test strips A distinctive colour change will
be observed.
Reducing Benedict’s test A Brick-red precipitate is formed.
sugars
Starch Iodine test Iodine solution changes from
brown to blue-black.

2.5 Lipids
9. Lipids are organic substances made up of carbon, hydrogen and
oxygen, with a hydrogen-oxygen ratio greater than 2:1. All lipids are
insoluble in water, but can dissolve in organic solvents.

10. Important lipids include triglycerides (fats and oils), phospholipids


and cholesterol:

© Aristo Educational Press Ltd. 2-3


HKDSE BIOLOGY: Connecting Concepts Revision notes

Characteristics Functions
Triglycerides • A triglyceride • Fats and oils act as
fatty acid 1 molecule is formed energy reserves in
by the condensation organisms.
glycerol

fatty acid 2
of one glycerol
• Subcutaneous fat
fatty acid 3
molecule and three
acts as an insulating
fatty acid molecules,
layer to reduce heat
with the removal of
loss.
three water
molecules. • Adipose tissues
around internal
• The three fatty acid
organs act as a
molecules may be
shock-absorber.
the same or different.
Phospholipids A phospholipid molecule As the main component
fatty acid 1 consists of one glycerol of cell membranes
phosphate molecule, two fatty acid
glycerol

molecules and a
group fatty acid 2

phosphate group.

Cholesterol Complex molecules • Essential component


consisting of carbon of cell membranes
rings
• Used in the synthesis
of lipid hormones

11. The presence of lipids can be indicated by the grease spot test.
Lipids leave a translucent spot on filter paper, which disappears when
it comes into contact with an organic solvent.

2.6 Proteins
12. Proteins are organic substances made up of carbon, hydrogen,
oxygen and nitrogen. Some also contain sulphur.

© Aristo Educational Press Ltd. 2-4


HKDSE BIOLOGY: Connecting Concepts Revision notes

13. The basic units of proteins are amino acids. Each amino acid
molecule has an amino group, a carboxyl group and a specific side
chain.
side chain
R
H O
N C C
H OH
H
amino group carboxyl group

14. Dipeptides and polypeptides are formed when amino acids join
together by condensation. The amino acid sequence affects the final
shape of the protein molecule.

15. Proteins have the following functions in organisms:


• As components of the cytoplasm and the cell membrane, thus
important for the growth and repair of body tissues
• Forming haemoglobin, enzymes, antibodies and certain hormones
• As an energy source if carbohydrates and lipids are used up

16. The presence of proteins can be indicated using protein test strips
which give a distinctive colour change when in contact with proteins.

2.7 Nucleic acids


17. Nucleic acids are organic substances made up of carbon, hydrogen,
oxygen, nitrogen and phosphorus. There are two types of nucleic
acids: deoxyribonucleic acids (DNA) and ribonucleic acids (RNA).

18. The basic units of nucleic acids are nucleotides. Each nucleotide
has three components: a five-carbon sugar, a nitrogenous base
and a phosphate group.

© Aristo Educational Press Ltd. 2-5


HKDSE BIOLOGY: Connecting Concepts Revision notes

nitrogenous base
phosphate (A, T, G or C in DNA; and
group A, U, G or C in RNA)

5-carbon sugar
(deoxyribose in
DNA; ribose in RNA )

19. Nucleic acids play important roles in heredity and protein synthesis.

20. Comparison between DNA and RNA:

DNA RNA
5-carbon sugar Deoxyribose Ribose
Nitrogenous base Adenine (A), thymine (T), Adenine (A), uracil (U),
guanine (G) or cytosine guanine (G) or cytosine
(C) (C)
Structure Double helix Single chain

© Aristo Educational Press Ltd. 2-6

Common questions

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Biochemical tests are crucial for detecting specific macromolecules. The glucose test strips and Benedict's test for reducing sugars identify energy sources and metabolic disorders. The iodine test for starch and grease spot test for lipids inform on diet and metabolic energy reserves. Protein test strips are vital for detecting protein deficiencies or imbalances. These tests provide a foundational understanding of organismal health and metabolic states .

Beyond energy storage and insulation, lipids play structural roles as phospholipids in cell membrane bilayers, contributing to compartmentalization and barrier functions. Cholesterol stabilizes membranes, maintaining fluidity and aiding in forming lipid rafts important for signaling. Lipids also act as precursors for steroid hormones, vital in regulating physiological processes like metabolism, immune response, and reproduction .

Polysaccharides like cellulose cannot be digested by humans due to the absence of enzymes capable of breaking beta-glycosidic bonds. As a result, cellulose passes through the digestive system largely unchanged, contributing to dietary fiber. This fiber aids in digestion by promoting bowel movement, adding bulk, and assisting in the maintenance of gut health .

If phospholipids in cell membranes were replaced with other lipids, cell membrane integrity and functionality would be compromised. Phospholipids' amphipathic nature allows for the formation of a bilayer structure essential for separating the internal environment from external conditions while allowing selective permeability and fluidity. Without this, membrane-bound processes like signal transduction, material transport, and cell communication would be disrupted, severely affecting cell viability and functions .

The molecular structure of carbohydrates determines their solubility and energy storage roles. Monosaccharides, being simple and soluble, are quick energy sources. Disaccharides also serve as quick energy sources due to their solubility, whereas polysaccharides, being insoluble, are suited for energy storage (starch in plants and glycogen in animals) and structural roles (cellulose in plant cell walls).

Water serves several critical roles in organisms: it acts as a solvent, facilitating the transport of substances and the medium for chemical reactions; it's a reactant in metabolic reactions, such as photosynthesis and hydrolysis; it regulates body temperature through evaporation in cooling; and provides structural support as a temperature buffer to maintain homeostasis .

Proteins serve structural roles by being components of cytoplasm and cell membranes, aiding in tissue growth and repair. Functionally, they form enzymes that catalyze metabolic reactions, hormones for signaling, antibodies for immune defense, and provide an energy source if necessary. Their diverse amino acid sequences allow precise functional and structural roles .

Inorganic ions like nitrate and iron are crucial for plants. Nitrate is necessary for synthesizing proteins, nucleic acids, and chlorophyll, impacting growth and photosynthesis. Iron is essential for chlorophyll formation and functioning as a part of electron transport in chloroplasts. Deficiencies in these ions can lead to stunted growth, chlorosis (yellowing of leaves), and diminished photosynthetic abilities .

Triglycerides consist of three fatty acids attached to a glycerol molecule and primarily serve as energy reserves, insulation, and protection. Phospholipids have two fatty acids and a phosphate group connected to a glycerol molecule, which confers them amphipathic properties essential for forming cellular membranes, creating a bilayer that separates cell contents from the environment .

DNA's double-helix structure provides stability for long-term genetic information storage, using bases adenine, thymine, guanine, and cytosine for base-pairing stability. RNA, being single-stranded with ribose sugar and uracil instead of thymine, is more flexible and less stable, suitable for temporary genetic information transmission and protein synthesis as mRNA, tRNA, and rRNA, enabling various cellular roles .

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