SwissTargetPred

Target Common name Uniprot ID

Carbonic anhydrase II CA2 P00918
Arachidonate 5-lipoxygenase ALOX5 P09917
Carbonic anhydrase VII CA7 P43166
Carbonic anhydrase I CA1 P00915
Carbonic anhydrase VI CA6 P23280
Matrix metalloproteinase 9 MMP9 P14780
Carbonic anhydrase XII CA12 O43570
Matrix metalloproteinase 1 MMP1 P03956
Matrix metalloproteinase 2 MMP2 P08253
Protein-tyrosine phosphatase 1B PTPN1 P18031
Carbonic anhydrase XIV CA14 Q9ULX7
Carbonic anhydrase IX CA9 Q16790
Carbonic anhydrase VB CA5B Q9Y2D0
Carbonic anhydrase VA CA5A P35218
Carbonic anhydrase III CA3 P07451
Aldose reductase AKR1B1 P15121
Estrogen receptor beta ESR2 Q92731
Carbonic anhydrase IV CA4 P22748
Aldo-keto reductase family 1 member B10 AKR1B10 O60218
Hydroxycarboxylic acid receptor 2 HCAR2 Q8TDS4
Macrophage migration inhibitory factor MIF P14174
Carbonic anhydrase XIII CA13 Q8N1Q1
Quinone reductase 2 NQO2 P16083
Toll-like receptor 4 (by homology) TLR4 O00206
Receptor protein-tyrosine kinase erbB-2 ERBB2 P04626
Estrogen receptor alpha ESR1 P03372
Norepinephrine transporter SLC6A2 P23975
Transthyretin TTR P02766
MAP kinase ERK2 MAPK1 P28482
Aldo-keto-reductase family 1 member C3 AKR1C3 P42330
Aldo-keto reductase family 1 member C4 AKR1C4 P17516
Aldo-keto reductase family 1 member C2 AKR1C2 P52895
Tyrosine-protein kinase SYK SYK P43405
Beta amyloid A4 protein APP P05067
Epidermal growth factor receptor erbB1 EGFR P00533
Tyrosine-protein kinase FYN FYN P06241
Tyrosine-protein kinase LCK LCK P06239
Cyclooxygenase-1 PTGS1 P23219
PI3-kinase p110-beta subunit PIK3CB P42338
Cytochrome P450 1A2 CYP1A2 P05177
Cytochrome P450 2C9 CYP2C9 P11712
Cytochrome P450 3A4 CYP3A4 P08684
Cytochrome P450 2C19 CYP2C19 P33261
PI3-kinase p110-alpha subunit PIK3CA P42336
Leukocyte elastase ELANE P08246
Coagulation factor VII/tissue factor F3 P13726
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845
Nuclear factor erythroid 2-related factor 2 NFE2L2 Q16236
Signal transducer and activator of transcription 3 STAT3 P40763
Monoamine oxidase B MAOB P27338
Protein kinase C theta PRKCQ Q04759
Cyclooxygenase-2 PTGS2 P35354
Nuclear factor NF-kappa-B p65 subunit RELA Q04206
Hepatocyte growth factor receptor MET P08581
Cyclin-dependent kinase 2/cyclin E1 CCNE1 CDK2 P24864 P24941
Tubulin beta-1 chain TUBB1 Q9H4B7
Protein tyrosine kinase 2 beta PTK2B Q14289
C-terminal-binding protein 2 CTBP2 P56545
Low affinity neurotrophin receptor p75NTR NGFR P08138
Progesterone receptor PGR P06401
Thrombin F2 P00734
Glutamate receptor ionotropic kainate 1 GRIK1 P39086
Thiopurine S-methyltransferase TPMT P51580
Leucine aminopeptidase LAP3 P28838
G protein-coupled receptor 44 PTGDR2 Q9Y5Y4
Lysine-specific demethylase 4D-like KDM4E B2RXH2
Cytochrome P450 1B1 CYP1B1 Q16678
Neprilysin MME P08473
Transient receptor potential cation channel subfamily A memberTRPA1 O75762
Fructose-1,6-bisphosphatase FBP1 P09467
Cytochrome P450 1A1 CYP1A1 P04798
Adenosine A1 receptor ADORA1 P30542
Adenosine A2a receptor ADORA2A P29274
Adenosine A2b receptor ADORA2B P29275
Cyclin-dependent kinase 4/cyclin D1 CCND1 CDK4 P24385 P11802
AMP deaminase 3 AMPD3 Q01432
Arachidonate 15-lipoxygenase ALOX15 P16050
Protein kinase C epsilon PRKCE Q02156
Histone acetyltransferase p300 EP300 Q09472
Nitric oxide synthase, inducible NOS2 P35228
Beta-secretase 1 BACE1 P56817
Prostaglandin E synthase PTGES O14684
Toll-like receptor (TLR7/TLR9) TLR9 Q9NR96
Solute carrier family 13 member 5 SLC13A5 Q86YT5
Lysine-specific demethylase 4A KDM4A O75164
Endothelin-converting enzyme 1 ECE1 P42892
GABA-B receptor (by homology) GABBR1 Q9UBS5
Angiotensin-converting enzyme ACE P12821
Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1 O75460
Glycogen synthase kinase-3 beta GSK3B P49841
Telomerase reverse transcriptase TERT O14746
Alpha-synuclein SNCA P37840
Glutamate receptor ionotropic, AMPA 4 GRIA4 P48058
Kynurenine 3-monooxygenase (by homology) KMO O15229
CDC7/DBF4 (Cell division cycle 7-related protein kinase/ActivatorDBF4 CDC7 Q9UBU7 O00311
T-cell protein-tyrosine phosphatase PTPN2 P17706
DNA topoisomerase II alpha TOP2A P11388
Poly [ADP-ribose] polymerase-1 PARP1 P09874
Aldo-keto reductase family 1 member C1 AKR1C1 Q04828
Glutamate carboxypeptidase II FOLH1 Q04609
 SwissTargetPrediction
ChEMBL ID Target Class Probability*
CHEMBL205 Lyase 0.73930393802
CHEMBL215 Oxidoreductase 0.73930393802
CHEMBL2326 Lyase 0.73930393802
CHEMBL261 Lyase 0.73930393802
CHEMBL3025 Lyase 0.73930393802
CHEMBL321 Protease 0.73930393802
CHEMBL3242 Lyase 0.73930393802
CHEMBL332 Protease 0.73930393802
CHEMBL333 Protease 0.73930393802
CHEMBL335 Phosphatase 0.73930393802
CHEMBL3510 Lyase 0.73930393802
CHEMBL3594 Lyase 0.73930393802
CHEMBL3969 Lyase 0.73930393802
CHEMBL4789 Lyase 0.73930393802
CHEMBL2885 Lyase 0.212408695957
CHEMBL1900 Enzyme 0.150923844771
CHEMBL242 Nuclear receptor 0.150923844771
CHEMBL3729 Lyase 0.150923844771
CHEMBL5983 Enzyme 0.080569968052
CHEMBL3785 Family A G protein-coupled receptor 0.080569968052
CHEMBL2085 Enzyme 0.080569968052
CHEMBL3912 Lyase 0.080569968052
CHEMBL3959 Enzyme 0.0717871625222
CHEMBL5255 Toll-like and Il-1 receptors 0.0717871625222
CHEMBL1824 Kinase 0.0717871625222
CHEMBL206 Nuclear receptor 0.0717871625222
CHEMBL222 Electrochemical transporter 0.0717871625222
CHEMBL3194 Secreted protein 0.0717871625222
CHEMBL4040 Kinase 0.0717871625222
CHEMBL4681 Enzyme 0.0717871625222
CHEMBL4999 Enzyme 0.0717871625222
CHEMBL5847 Enzyme 0.0717871625222
CHEMBL2599 Kinase 0.0717871625222
CHEMBL2487 Membrane receptor 0.0717871625222
CHEMBL203 Kinase 0.0717871625222
CHEMBL1841 Kinase 0.0717871625222
CHEMBL258 Kinase 0.0717871625222
CHEMBL221 Oxidoreductase 0.0717871625222
CHEMBL3145 Enzyme 0.0717871625222
CHEMBL3356 Cytochrome P450 0.0717871625222
CHEMBL3397 Cytochrome P450 0.0717871625222
CHEMBL340 Cytochrome P450 0.0717871625222
CHEMBL3622 Cytochrome P450 0.0717871625222
CHEMBL4005 Enzyme 0.0717871625222
CHEMBL248 Protease 0.0717871625222
CHEMBL4081 Surface antigen 0.0717871625222
CHEMBL4235 Enzyme 0.0717871625222
CHEMBL1075094 Unclassified protein 0.0717871625222
CHEMBL4026 Transcription factor 0.0717871625222
CHEMBL2039 Oxidoreductase 0
CHEMBL3920 Kinase 0
CHEMBL230 Oxidoreductase 0
CHEMBL5533 Transcription factor 0
CHEMBL3717 Kinase 0
CHEMBL1907605 Kinase 0
CHEMBL1915 Structural protein 0
CHEMBL5469 Kinase 0
CHEMBL3797016 Unclassified protein 0
CHEMBL4762 Membrane receptor 0
CHEMBL208 Nuclear receptor 0
CHEMBL204 Protease 0
CHEMBL1918 Ligand-gated ion channel 0
CHEMBL2500 Enzyme 0
CHEMBL3965 Protease 0
CHEMBL5071 Family A G protein-coupled receptor 0
CHEMBL1293226 Eraser 0
CHEMBL4878 Cytochrome P450 0
CHEMBL1944 Protease 0
CHEMBL6007 Voltage-gated ion channel 0
CHEMBL3975 Enzyme 0
CHEMBL2231 Cytochrome P450 0
CHEMBL226 Family A G protein-coupled receptor 0
CHEMBL251 Family A G protein-coupled receptor 0
CHEMBL255 Family A G protein-coupled receptor 0
CHEMBL1907601 Kinase 0
CHEMBL2912 Enzyme 0
CHEMBL2903 Enzyme 0
CHEMBL3582 Kinase 0
CHEMBL3784 Writer 0
CHEMBL4481 Enzyme 0
CHEMBL4822 Protease 0
CHEMBL5658 Enzyme 0
CHEMBL5804 Toll-like and Il-1 receptors 0
CHEMBL3769293 Electrochemical transporter 0
CHEMBL5896 Eraser 0
CHEMBL4791 Protease 0
CHEMBL2064 Family C G protein-coupled receptor 0
CHEMBL1808 Protease 0
CHEMBL1163101 Enzyme 0
CHEMBL262 Kinase 0
CHEMBL2916 Enzyme 0
CHEMBL6152 Unclassified protein 0
CHEMBL3190 Ligand-gated ion channel 0
CHEMBL2145 Oxidoreductase 0
CHEMBL2111377 Kinase 0
CHEMBL3807 Phosphatase 0
CHEMBL1806 Isomerase 0
CHEMBL3105 Enzyme 0
CHEMBL5905 Enzyme 0
CHEMBL1892 Protease 0
Known actives (3D/2D)
23 / 13
1 / 29
9 / 19
19 / 16
7 / 15
2 / 35
14 / 14
2 / 34
2 / 36
11 / 2
8 / 18
11 / 18
4 / 13
5 / 14
4/ 3
9 / 35
1 / 10
3/ 8
0 / 18
0/ 1
1/ 1
4 / 10
0 / 17
0 / 20
0/ 3
0 / 22
0/ 3
0/ 5
0/ 1
0 / 19
0/ 1
0/ 1
0/ 1
0 / 44
3 / 38
2/ 2
2/ 6
1 / 20
0/ 1
0/ 5
0/ 3
0/ 3
0/ 3
0/ 1
0/ 2
0/ 9
0/ 6
0/ 4
0/ 1
1 / 17
0/ 3
6 / 21
0 / 10
0 / 19
0/ 1
0 / 19
0/ 1
6/ 0
1/ 0
0/ 2
9/ 0
17 / 0
4/ 0
2/ 0
1/ 0
3/ 0
0 / 25
4/ 0
0/ 1
8/ 0
0/ 9
0/ 2
0/ 2
0/ 1
0/ 1
3/ 0
0/ 1
0/ 2
0/ 3
0/ 3
0 / 56
0 / 16
0/ 3
8/ 0
3/ 0
3/ 0
3/ 0
2/ 0
5/ 0
0/ 8
0/ 2
0/ 3
3/ 0
12 / 0
1/ 0
1/ 0
0/ 1
3/ 0
0/ 1
6/ 0