APES Unit 5: Risk and Toxicology Notes
APES Unit 5: Risk and Toxicology Notes
Questions/Keywords Notes
Note: Know how to determine the LD50 for a hypothetical dose (via a
graph. Find y = 50).
Summary
The risk and toxicity of something depends on many factors, and the resulting impact (toxicity)
can be measured in several ways. Risk and toxicity have their own separate methods of
measurement and scaling, and different methods of management.
Questions/Keywords Notes
Mutagens - Chemicals - The lower the LD50, the more dangerous/toxic a chemical is
or environmental - Hazardous chemicals cause harm by:
factors that induce - Provocation of allergic reactions
changes in DNA - Interruption of oxygen uptake
- Irritation of lungs or skin
Carcinogens -
- Being explosive or flammable
Compounds that
- Ultraviolet radiation can damage DNA by changing a CC
promote malignant
growth of cells called sequence into a TT
tumors - Teratogens:
- Heavy metals
Teratogens - - Steroid hormones
Chemicals that cause - Alcohol
physical birth defects - Polychlorinated biphenyls (PCBs)
during gestation - Medications
(pregnancy) - Fun fact, Thalidomide was used for morning sickness but it was
actually horrible for birth defects
Neurotoxins - - Symptoms of neurotoxin exposure:
Chemicals that - Weakness or paralysis
disrupt the - Altered sensations, tingling, and numbness
transmission of - Headaches, memory, and concentration problems
chemical signals - Loss of vision
between neurons - Depression
- Uncontrollable obsessive-compulsive behaviors
- Sexual dysfunction
- Confusion
- Personality changes
- HAAs:
- Estrogen mimics
- Androgen mimics
- Testosterone blockers
- Thyroid disruptors
Summary
The lower the LD50, the more dangerous/toxic a chemical is. Different chemicals cause
different effects.
Course APES Video # Video 14.03: Biological Hazards
Name and Name
Questions/Keywords Notes
Summary
Transmissible and non-transmissible diseases are both dangerous. Antibiotics are often used
to fight diseases, but sometimes people use them even when not needed, or use them to the
excess. This is bad.
Questions/Keywords Notes
- Risk Analysis:
- Risk assessment (identifying specific hazards and their
affiliated risks)
- Comparative risk analysis (ranking risks determined)
- Risk management (analyzing options)
- Risk communication (educating decision-makers on the
risks)
- Method 1: Cost-benefit analysis: compares the short or
long-term benefits or risks to using or foregoing a certain
chemical or technology
- A risk is acceptable if the benefits outweigh the costs
- Method 2: Expressed preferences, survey to see how many
people are willing to do it
- Method 3: Natural standards, acceptable risks
- Method 4: Revealed preferences, new risk is also acceptable as
long as it's not worse than the current conditions
- Environmental risks:
- Air pollution and climate change
- Deforestation
- Species extinction
- Soil degradation
- Overpopulation
- Human reliability x Technology reliability = System reliability %
- Human reliability is low, unpredictable; technological reliability
is high
- Too much of something can kill you. Even too much water can
kill you. If you drink too much water too fast, your body goes
into a state of hyponatremia. Essentially, your body’s normal
electrolyte levels become too dilute, and you can die.
-
Summary
Risk is different from every point of view, and most humans don’t recognize risk correctly.
Questions/Keywords Notes
CFCs and BFCs are - Troposphere: 75-80% of the air of the Earth, and we live there
extremely stable - Troposphere (0-12 km) -> Stratosphere (50 km) -> Mesosphere
organohalogen (50-80 km) -> Thermosphere (80-700 km) -> Exosphere
compounds that easily (700-10,000 km)
survive ascension to - 95% of the harmful UVB rays of sun are stopped by the ozone
the stratosphere where - Ozone gives the greenhouse effects and heats the Earth
UV light slowly breaks
- The ozone chemical:
them apart.
- Discovered in 1913 by GH Dobson
- First measured using the Dobson developed
spectrophotometer
- Each molecule of chlorine or bromine is capable of ripping apart
more than 100,000 molecules of ozone
- Organohalogen breakdown factors:
- Low winter temperatures
- Formation of polar stratospheric clouds (PSCs)
- PSCs are composed of hydrated nitric acids, sulfuric
acids, and exist in both liquid and solid form.
- The ozone hole is the most prominent in Antarctica during the
coldest time of late winter to early spring (around September)
- Ozone layer destruction has resulted in decreased absorption
of radiation, including UVB
- Montreal Protocol: A treaty signed by 197 nations in 1987 to
solve the ozone depletion problem
- Ozone compromising substances:
- Bromine
- Chlorine
- Chlorofluorocarbons (CFCs)
- Tropospheric ozone
- UV light enters atmosphere
- UV chemically reacts with air pollutants
- Tropospheric ozone is created
- Ozone at the Earth’s surface damages living tissues in
organisms, especially in plants and lungs
- Ozone exacerbates other conditions:
- Emphysema
- Bronchitis
- Heart disease
- Chest congestion
- Eye problems
- Asthma
- Tropospheric ozone:
- Fades paints, fibers, and dyes
- Degrades rubber
- Reducing fossil fuel combustion is the first step in reducing
tropospheric ozone
Summary
Ozone, primarily located in the stratosphere, is very beneficial to our Earth. It keeps us warm,
and protects us from harmful UV radiation. However, ozone is better off up there, because if it
gets close to us, bad things can happen.
Questions/Keywords Notes
Summary
Questions/Keywords Notes
Summary
Smog is really bad, it has killed people in the past; pollutants in the air can be dispersed in
several ways, but that doesn’t entirely remove the pollution from the Earth.
Course APES Video # Video 15.03: Photochemical Smog
Name and Name
Questions/Keywords Notes
Summary
Smog is really bad, it has killed people in the past; pollutants in the air can be dispersed in
several ways, but that doesn’t entirely remove the pollution from the Earth.
Questions/Keywords Notes
Acid rain: A mixture - Acid rain doesn’t have to be rain (it could be clouds, fog, etc.)
of acidic substances - Industrial plants: Smokestacks are intended to be tall enough to
forming in the release pollutants above a possible inversion layer
atmosphere and - Raiden pH
descending as - Normally pH 5.6
precipitation - With pollution added pH is 4.2 to 4.7 (10 times more
acidic)
- Eastern Forest pH:
- Dew and fog that settles in the forests have a pH 2.3
(1,000 times more acidic)
- About as acidic as a lemon
- Neutral pH:
- The concentration of hydrogen and hydroxyl ions are
equal
- Represented by 7 on the logarithmic scale
- A one unit change represents a tenfold change in
hydrogen concentrations
- Neutralizing Soils: The hydrogen ions of the acid precipitations
are buffered when filtered through limestone or calcium
carbonate containing rocks
- Regions sensitive to acid deposition:
- Lack neutralizing soils, or comprised mainly of granite
- Soil capacity to buffer has been depleted to acidic
deposition
- Health effects of acid deposition:
- Sulfur dioxide and nitrogen oxides are lung irritants
- Metal salts from soil can make their way into crops
- Toxic metals may be lixiviated from pipes in drinking
water
- Aquatic systems, soils, and plants all suffer damage when the
pH falls below 6, and especially below 5
- Aquatic system acid shock: occurs after a sudden runoff of
aluminum ions and low pH waters into lakes and streams
- Chronic acidity: monitoring the waters of the Adirondacks,
Catskills, and Appalachian mountains show increased sulfate
and nitrate ions
- Calcium carbonate:
- Found in limestone
- Alkaline pH 9.9
- Can be expensive
- A temporary fix
- Kills some aquatic plants and plankton
- Quantity unknown
- Acid deposition: Needles and leaves are directly damaged,
these detriments reduce productivity and the soil’s buffering
abilities
- Acid deposition:
- Reacts to mobilize toxic mercury, cadmium, and lead
- Encourages the growth of ericaceous or calcifuge plants
and mosses
- Weakens trees
- Reduction solutions:
- Improve energy efficiency
- A marked reduction in carbon-based fuel use
- Reduce our dependence on all nonrenewable resources
- Increase standards for removing pollution from industrial
emissions
Summary
Acid rain, the mixture of acidic substances formed in the atmosphere then descended as
precipitation, is bad for living things.
Questions/Keywords Notes
Summary
Indoors, there can be pollution as well. Various things that we commonly do can cause
pollution, and many of these things are harmful to our wellbeing.
Questions/Keywords Notes
Summary
Our world needs cleaner air, and there have been certain procedures taken to achieve such a
goal. There are many different methods.
Questions/Keywords Notes
Climate Forcings:
Various factors and
atmospheric
components
influence the
effective radiative
forcing of our
atmosphere, and shift
this equilibrium
Milankovitch cycles:
shape of the Earth’s
orbit which fluctuates
between more and
less elliptical
Summary
There are many possibilities to the reason for our global warming and odd climate change
pattern, but the most likely reason is that humans are affecting the atmosphere, not the
various natural events that occur at regular, controlled intervals.
Summary
The video talks about the effect that humans have had on global warming, and the impactful
result from all of it, including our inability to fully cure the Earth unless we take proper action
and allow the course to right itself eventually.
Questions/Keywords Notes
Thermal Expansion: the - Humans had started recording climate before 1880, the modern
tendency of matter to thermometer was invented in the 1700s
expand in response to - Proxy Indicators: Pieces of information that give us clues about
increase in temperature the paleoclimate and hard baseline data of the history of
atmospheric gasses, providing indirect evidence such as dust
content, methane concentrations, and abundance of oxygen
isotopes
- Evidences found in the trapped air within glaciers:
- Frequency of fires
- Solar activity
- Snowfall
- Temperature trends
- Greenhouse gas concentrations
- While climate change is anthropogenic, the beavers’ gradual
migration to the north is exacerbating the condition, causing
large chunks of permafrost to thaw.
- Permafrost has 2x as much carbon as what already exists in the
atmosphere
- Permafrost thawing could contribute 1.7 degrees Fahrenheit to
the Earth’s warming
- Ice loss has doubled since the 1990s, accounting for a 4%
increase in sea level
- Intergovernmental Panel on Climate Change (IPCC)
- Established in 1988 by the U.N. and the World
Meteorological Organization
- Comprised of government representatives and hundreds
of international scientists
- Publishes reports of global impacts due to climate
change
- Sixth assessment report in 2017:
- Documented observations of precipitation,
temperature, snow and ice cover, storm intensity,
and sea levels
- Predicted impacts on both ecosystems and
humans
- Discussed strategies in response to these
changes
- Thermal expansion of the ocean is the most important factor
contributing to an increase in sea level
Summary
We learn about the reasons and evidence behind sea level rises and our overall modern
climate change problems, which features thermal expansion, beavers, ice loss, etc.
Questions/Keywords Notes
Summary
Paleoclimatology tells us details of the Earth’s warming climate and many of the numerous
variables that are actively participating in global warming.
Course APES Video # Video 16.05: Effects of Climate Change
Name and Name
Questions/Keywords Notes
Summary
Climate change has a large impact on all systems on the Earth, such as the water levels rising,
and many other harsh effects on human beings.
Questions/Keywords Notes
Summary
To change our world for the better, we must conduct a successful mixture of mitigation and
adaptation, so there is less room for future suffering.
Questions/Keywords Notes
Summary
- He explains the difference between ancient carbon from fossil fuels and from other
sources
Questions/Keywords Notes
Summary
Dr. Tara is very passionate about educating students in a non-robotic, compassionate manner.
She shows a deeper understanding and feel for the works of science, and she has experienced
a robotic past before, so she understands how it was like and how she can bring a change to
its mindset.
Questions/Keywords Notes
Summary
Questions/Keywords Notes
Summary
Many types, effects, and sources of water pollution come from anthropogenic behavior, such
as infectious agents from human waste, fertilizer from human crops, and thermal pollution
from human industrial factories.
Course APES Video # Video 17.02: Freshwater Pollution
Name and Name
Questions/Keywords Notes
Oxygen Sag Curve - - Aquatic biodiversity is directly affected by the water quality
illustrates the depth - Natural solutions cannot eliminate non-degradable pollution.
and width, therefore - Many natural pollutant degrading bacteria use oxygen, they
the time and space deplete the stream of dissolved oxygen. They remove
needed for the pollutants, but they cause eutrophication, aka harm the water.
waterway to recover - River caught on fire TWICE from being so polluted, second time
from the influx of a helped the inspiration to the Clean Air Act
pollutant - The residence time of a lake depends on the number of rivers
flowing in and out, the depth of the lake, and the volume
- Due to these factors, slow flow and smaller volumes,
ponds, reservoirs, and lakes are far more vulnerable than
rivers to contamination by
- Pesticides
- Oil
- Plant nutrients
- Heavy metal toxins (selenium, mercury, lead)
- Harmful toxins (devastating to freshwater ecosystems):
- Mercury
- PCBs
- DDT
- Cultural eutrophication: acceleration by humans for
eutrophication
- Preventing Cultural Eutrophication:
- Composting
- Converting decaying vegetation and food waste
into compost soil
- Breaks down and chemically binds the nitrate and
phosphate nutrients
- Limits nutrients that go into groundwater or runoff
- Helps prevent eutrophication
- Soil formed from composting decaying vegetation
and other organic material helps prevent
eutrophication and yields high quality soil with
high CEC
- Reducing pollution
- Methods to support this pollution reduction
strategy include reducing the discharge of
phosphate-containing household cleaners and
detergents, and limiting use of nitrogen based
fertilizers
- Strengthening laws and regulations against non
point-source pollution
- Ultrasonic irradiation
- Irradiation produces cavitations in algae cells
which collapses the cell’s air sacs
- Photosynthesis activity ceases and the cells die
without releasing toxins into the environment
- When it comes to the environmental damage,
prevention is always preferable to remediation
Summary
Aquatic biodiversity is directly affected by the water quality. Pollution is caused by a numerous
amount of factors.
Questions/Keywords Notes
- The plume edge may leak into surface waters and render that
water supply unusable or unsafe
- Surface water pollutants are similar to groundwater pollutants,
just via different mechanisms and in different quantities.
Specifications range from:
- Radioactive
- Bacteriological
- Chemical
- Organic
- Inorganic
- Physical
- These include:
- Pathogens
- Organic compounds
- Heavy metals (such as arsenic, fluoride, pharmaceuticals,
nitrates, even saltwater)
- Fecal Pathogens: Feces contain four types of pathogens:
- Helminth eggs
- Protozoa
- Viruses
- Bacteria
- Volatile organic compounds (or VOCs):
- Groundwater pollutants present due to negligent or
ignorant industrial practices; it wasn’t until the 1960s that
many compounds were known to the be harmful, and
identified in drinking water sources
- Industrial solvents used in dry cleaning:
- Tetrachloroethylene
- TCE (trichloroethylene)
- Widespread use as an anesthetic in the food
industry to extract vegetable oils from plant
materials, like decaffeinating coffee, and its
famous metal degreasing abilities
- Now a known carcinogen
- Vinyl chloride
- Polycyclic Aromatic Hydrocarbons:
- Exist naturally as creosote and are a result of incomplete
combustion of organic material
- Metals
- Weathering leaches trace metals from the soil into
groundwater
- Chromium, cadmium, and lead are the toxic
contaminants that have migrated into water stores from
solid waste disposal, metallurgy, and mining
- The mobility of metal or metalloid depends on:
- Partitioning of contaminants through the soil
- Chemistry of the reduction-oxidation reaction
- pH of the groundwater
- Two most serious contaminants for drinking water are arsenic
and fluoride
- Ingesting excess fluoride:
- Skeletal/dental fluorosis
- Loss of bone elasticity
- Loss of joint mobility
- Joint pain/osteoarthritis
- Pharmaceuticals are a common drinking water contaminant
- Tranquilizers
- Decongestants
- Antidepressants
- Anti-inflammatories
- Antibiotics
- The most common chemical contaminant of groundwater stores
are nitrates
- Saltwater Intrusion: Action of salt water moving into and
contaminating fresh water aquifers
- This intrusion exists in coastal aquifers where salt water
pushes inland beneath fresh groundwater
- Transition zone is where they mix via diffusion and
dispersion
- Sustainable Groundwater Management Act
Summary
Questions/Keywords Notes
Summary
Many pollutants, mostly caused by humans, pollute the ocean and its marine waters, life, and
habitat.
Questions/Keywords Notes
- All of the agricultural runoff that are polluting surface waters are
from pesticides, fertilizers, and erosion
- Feedlot runoff is particularly high in manure
- If sewer systems are not maintained, they can become leaky
and more expensive to repair
- Sometimes when sewer plants overflow, they can runoff and let
raw sewage water into open bodies of water
- Sewage Treatment
- Primary step: Physical, and removes suspended solids;
removes about 69% of suspended solids and 24% of
organic wastes
- Does not remove: Pesticides, Radioisotopes, Salts,
Nitrates, Phosphates
- Secondary step: Biological, 90% of the remaining organic
waste is degraded by aerobic bacteria
- Tertiary Sewage Treatment: Combines physical and
chemical processes to remove specific pollutants
remaining after the first two steps
- Only 5% of wastewaters in the United States rae
treated to these expensive extra measures
- Water is bleached and disinfected with the most
common method being chlorination
- Settling Tank: allows suspended solid to settle out as
sludge
- Sludge is a gooey, thick mixture of solids and
bacteria, includes metal and chemicals if
household wastes are combined with industrial
wastes
- Sludge is digested by anaerobic bacteria and
produces compost to nutrify soil
- Waterless Composting Toilets
- These systems are much less expensive to maintain and
would help eliminate sewer repair and ease the
operation and cost of wastewater treatment plants
- Treating sewage could also be done via wetlands, either natural
or artificial
- Low tech and extremely low cost in comparison to waste
water treatment facilities
- Step 1: Sedimentation tank: where the solids settle into
sludge; the sludge is removed, and the remaining wastes
are broken down by bacteria for a month
- Step 2: Oxidation pond: Oxidation ponds where the
remaining wastes are broken down by bacteria for a
month
- Step 3: Artificial marsh: Bacteria and plants further
cleanse and filter the water in the artificial marsh
- Scott Pruitt (Trump-assigned guy):
- Weakened federal power over streams and wetlands by
contending that the only waters meriting protection were
the navigable waters and did not include the seasonal or
shallow watersheds and wetlands
Summary
A lot of surface water pollution originates from sewage water– there are many different
treatment plans for sewage water.
Summary
The quality of our drinking water is extremely important, yet we pay little to no attention to the
cleanliness, and allow pollution to take a hold of the water we consume in our bodies.
Questions/Keywords Notes
Solid waste - trash, - The US, which only makes up 4.6% of the global population,
junk, the stuff we produces 33% of solid waste
throw away; most of - Largest volume in waste is e-waste
it ends up in a landfill - Commonly discarded items in the US:
- Edible food
Leachate: the rain - Unwanted toys
water that becomes - Aluminum foil
toxic as it percolates - Plastic bags
through the garbage - Wearable clothing
- Americans generate 258,000,000 tons of trash annually
- 27% is paper
- 14.6% is food waste
- 13.5% are yard trimmings
- 12.8% are plastics
- & so on
- About 34% of our generated solid waste is either
composted or recycled
- Open dumps are just the landfills you think of, often
non-selective about the wastes that they receive and wastes
will degrade very slowly because they get buried under more
trash and soil, chemicals can easily run into groundwater
- Sanitary landfills are more selective solid wastes spread out in
layers and compacted down and covered with plastic, foam, or
clay
- Tires are unique; when left to degrade in a landfill or even a
vacant, empty lot, they leach extremely toxic chemicals into the
surroundings
- Some companies attempt to get rid of them via
incineration, but this releases toxins into the atmosphere,
tires burn extremely hot and long, which can cause a
dangerous and difficult fire control situation
- Old tires can be reclaimed into:
- Asphalt and pavement
- Playground underfooting
- Building material
- MSW is burned to produce steam which spins turbines and
produces electricity
- Incineration advantages:
- Quick and easy
- Low pollution of water
- Reduced waste volume
- Energy produced
- Incineration disadvantages:
- Releases toxic ash and dioxins
- High cost
- Encourages waste production
- Discourages reducing or reusing materials
- Citizen opposition
- 1st method for managing trash: Integrated Waste Management
- Reduce environmental harm by sorting waste and
disposing of each item in the most efficient and
environmentally friendly way possible
- Approaches to the integrated waste management:
- Landfill
- Recycling
- Incineration
- Composting
- The best way to manage waste is to stop making so much.
Summary
Solid waste, which is what we refer to as regular trash, has been consistently misused and
treated wrongly.
Questions/Keywords Notes
- Refuse: Simply refusing items before you take, buy, get, give
- Reduce: give consideration to each purchase you make; ask
yourself, is this really necessary? Is it packaged in something I
can reuse or repurpose? Can I get this item with less packaging,
or even better, can I make it myself?
- Reuse: Reuse. Like having a refillable water bottle or reusable
shopping bags, straws, to-go food containers, etc. Borrowing or
sharing tools you might not use all of the time, or wrapping a
present in a beautiful fabric and a nice silk ribbon
- Repair. Sometimes, a simple repair is all that it takes to
keep re-using an item you would otherwise throw away.
- Repurpose: you give it new life as something else
- The original intention of the item changes, another term
for this is upcycling
- Like using old tires, painted, and used as planters; or
wine bottles, used as light fixtures and flower pots;
plastic bottles to organize or store clothing, or to function
as container gardens for herbs
1. Consume less (make a smaller impact on your environment). If
you don’t buy it, it can’t become waste (or at least you won’t
turn it into waste)
2. Rethink manufacturing
3. Purchase sustainable products
4. Shift to service economy (Individuals would purchase and own
less)y
5. Eliminate unnecessary packaging
6. Pay-as-you-throw
7. Cradle-to-grave responsibility; the manufacturer is responsible
for the life of the product (generation -> disposal)
Summary
Refusing, reducing, reusing, and repurposing are many different ways that you and I can both
mitigate our ecological footprint.
Questions/Keywords Notes
Summary
Recycling is very important, there are several ways to do it, but the one we currently use
(single-stream recycling) is the worst, because it can cause bad contamination.
Questions/Keywords Notes
Summary
Recycling plastic and expecting it to end up being recycled rather than placed in a landfill can
be difficult due to numerous reasons, including the fact that many recycling facilities do not
accept all types of plastics.
Summary
Being careful of what you do and spend in your home is always possible and each little small
thing can make a huge impact– you have to start somewhere, and it doesn’t have to be big.
Summary
Hazardous waste comes in many shapes and forms, but 95% of which is not considered
“hazardous waste” by the US… thankfully, there are many ways to treat hazardous waste,
which can be sorted into two categories: Physical or chemical management, and biological
remediation.
Questions/Keywords Notes
Summary