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Immune System Overview: Lymphocytes and Functions

The document outlines the immune system's structure and function, detailing the origins and roles of B and T lymphocytes. It explains the processes of humoral and cell-mediated immune responses, including the importance of antigen recognition and the role of antigen-presenting cells. Additionally, it discusses organ transplantation and the significance of major histocompatibility complex in tissue matching.

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riyadandapani
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9 views2 pages

Immune System Overview: Lymphocytes and Functions

The document outlines the immune system's structure and function, detailing the origins and roles of B and T lymphocytes. It explains the processes of humoral and cell-mediated immune responses, including the importance of antigen recognition and the role of antigen-presenting cells. Additionally, it discusses organ transplantation and the significance of major histocompatibility complex in tissue matching.

Uploaded by

riyadandapani
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Immune

system

Lymphocytes ->
origin stem cell

after maturation
-
B lymphocyte from bone narrow
ye Primary Lymphoid organs
T
symphocyte from hym
-

Secondary lymphoid >


organ Spleen .
Bone marrow

B will be circulation
lymphocyte in
-

&
surface immunoglobulin >
-
capture milto
organisms
'
produce platma cells

/ -
few as
memory cells few as antibodies

Humosal immune
response

T lymphocyte - cannot
recognize antigen directly
LTH - CD4 receptor -

Helper cells -

recognises antigen
To -
CD8 receptor -

cytotoxic

Organ transplantation -
tissue a blood matching
chromosome 6 short arms-set of
genes

Major Histo
compatability complex mac S
3 set I - all nucleated cells (RBLX)
-
ogen
codes macrophages
# -> dendritic
langerhan
in) I
,
,
These cells help in
antigen
recognising
↓
Antigen presenting cell APC cells which express class
-

I MHL

After recognising >


-
20 %
memory ,
20 %
Cytokinin
↓ activates To cells
Cell mediated immune response ↓
destroys
microanin e

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