Case:
A 27 year old male is involved in a RTA.
He sustains a burst fracture of T2 with
complete neurological deficit below this
level. Fours hours following admission
his SpO2 is 85%, his blood pressure is
80/40 and his heart rate is 45.
How would you classify this patients'
haemodynamic status?
How would you manage this patient?
Case:
A 72 year old female is admitted complaining of
weakness, sweating and dysuria. Her temperature is
39C, pulse 130, BP 76/44, warm peripherally, lung fields:
reduced air entry bilaterally, oliguria, Hb 16 g/dl, WCC
27, PO2 8.2, Urine gram -ve bacilli, >105 organisms.
What is your diagnosis?
How would you classify this patients haemodynamic
status?
How would you manage this patient?
Shock
Shock
“A rude unhinging of the machinery of life”
“A brief pause in the act
of dying”
Fick Principle
Air’s gotta go in and out.
Blood’s gotta go round and round.
Any variation of the above is not a
good thing!
Shock
Inadequate oxygenation or
perfusion causes:
Inadequate cellular
oxygenation
Shift from aerobic to anaerobic
metabolism
AEROBIC METABOLISM
6 CO2
6 O2
6 H2O
METABOLISM
GLUCOSE 36 ATP
HEAT (417 kcal)
ANAEROBIC METABOLISM
2 LACTIC ACID
GLUCOSE METABOLISM 2 ATP
HEAT (32 kcal)
Ultimate
Effects of
Inadequate
Anaerobic Cellular
Metabolism Oxygen
Delivery
Lactic
Inadequate
Energy Anaerobic Acid
Production Metabolism Production
Metabolic Metabolic
Failure CELL Acidosis
DEATH
Maintaining perfusion
requires:
Volume
Pump
Vessels
Failure of one or more of these causes
shock
Definition:
A physiological state characterized by a
significant, systemic reduction in tissue
perfusion, resulting in decreased tissue
oxygen delivery and insufficient removal
of cellular metabolic products, resulting
in tissue injury.
TERMINOLOGY
Hypovolaemic shock Hypotension
Haemorrhagic shock Hypovolaemia
Haematogenic shock Oliguria & Anuria
Septic shock Hypoxaemia
Anaphylactic shock Systemic inflammatory
Spinal shock response
Neurogenic shock syndrome(SIRS)
Vasovagal shock Multiple organs
dysfunction
Cardiogenic shock syndrome(MODS)
TYPES OF SHOCK
Pathophysiology
Shock occurs when a diminished amount
of blood is available to the circulatory
system
The vascular system fails to hold the fluid
portion of the blood
Vasodilation of the blood vessels occurs
and disrupts the osmotic fluid balance in
the body
Pathophysiology
Plasma leave the blood and enter the
interstitial spaces
The formed elements remain in the blood
Blood viscosity increases
The rate of blood flow decreases
Insufficient amounts of O2 are being
transported in the blood
Renal responses to shock
In an effort to
sustain falling
blood pressure the
kidneys will help to
conserve body
fluids by reducing
the rate of urine
production.
Hormonal response to
shock
The neuro-endocrine
system responds to
shock by increasing
the secretion of anti-
diuretic hormone
(ADH), ADH causes
vasoconstriction and
an increased
reabsorption of water
in the nephrons - and
a decrease in urine
production
Predisposing Factors
Extreme fatigue
Extreme exposure to heat or cold
Extreme dehydration
Illness
Severe injury
Shock
Hypovolemic Shock = Low Volume
–Trauma –Vomiting
–Non-traumatic –Diuresis
blood loss –Sweating
Vaginal –Third space losses
GI Pancreatitis
GU Peritonitis
–Burns Bowel obstruction
–Diarrhea
Shock
Cardiogenic Shock = Pump Failure
–Acute M I –Mechanical
–CHF obstruction
–Bradyarrhythmias (“distributive shock”)
Cardiac tamponade
–Tachyarrhythmias Tension pneumothorax
Pulmonary embolism
Shock
Vasogenic Shock = Low Resistance
Spinal cord trauma
neurogenic shock
Depressant drug toxicity
Simple fainting
Shock
Mixed Shock
Septic Shock
Overwhelming infection
Inflammatory response occurs
Blood vessels
Dilate (loss of resistance)
Leak (loss of volume)
Shock
Mixed Shock
Septic Shock
Fever
Increased O2 demand
Increased anaerobic metabolism
Bacterial toxins
Impaired tissue metabolism
Shock
Mixed Shock
Anaphylactic Shock
Severe allergic reaction
Histamine is released
Blood vessels
Dilate (loss of resistance)
Leak (loss of volume)
Signs and Symptoms
Low Blood Pressure
Systolic BP is usually below 90 mmHg
Pulse is rapid and weak
Respiration is rapid and shallow
Skin is pale, cool, and clammy
Drowsiness
Classification of
Shock
•Hypovolemic
•Septic/Inflammatory
•Cardiogenic (Intrinsic, compressive &
Obstructive)
•Neurogenic
•Anaphylactic
Types of Shock
Hypovolemic Shock
Results from trauma in which there is
blood loss
Decreased blood volume causes a
decrease in blood pressure
Insufficient amounts of O2 is being
transported to body tissues and organs
Types of Shock
Respiratory Shock
Results when the lungs are unable to
supply enough O2 the circulating blood
Trauma that may produce respiratory
shock include:
Pneumothorax
Injury to the respiratory control center
Types of Shock
Neurogenic Shock
Results due to the overall dilation of the
blood vessels within the cardiovascular
system
Decreased blood pressure
Insufficient amounts of O2 is being
transported to body tissues and organs
Types of Shock
Psychogenic Shock
Commonly known as “fainting” (syncope)
Results due to a temporary dilation of the
blood vessels in the body causing a
decrease in the blood flow to the brain
Types of Shock
Cardiogenic Shock
Results due to the inability of the heart to
pump enough blood to the body
Decreased cardiac output
Decreased blood pressure
Insufficient amounts of O2 is being
transported to body tissues and organs
Types of Shock
Septic Shock
Results due to a severe infection
Usually a bacterial infection
Toxins released by the bacteria cause dilation
of the blood vessels within the cardiovascular
system
Decreased blood pressure
Insufficient amounts of O2 is being transported
to body tissues and organs
Types of Shock
Anaphylactic Shock
Results due to a severe allergic reaction
Allergic reaction may be caused by:
Foods
Insect bites
Drugs
Inhaling dusts, pollens, etc…
Types of Shock
Metabolic Shock
Results due to a severe illness that goes
untreated
For example, untreated diabetes
Results due to an extreme loss of bodily fluid
For example, excessive urination, diarrhea, or
vomiting
Psychological Impact
Shock can be compounded, or produced
by the psychological reaction to an injury
or a situation
Fear is the commonest
Provide reassurance and comfort
Immediate Management
Immediate Management
Maintain normal body temperature
In most cases, elevate the feet and legs above
the level of the heart
Exceptions include:
Neck injury – immobilize in the position found
Head injury – elevate the head and shoulders
Leg fracture – splint and elevate
Secondary Management
Secondary Management
Vital Signs
Pulse Pupils
Respiration Level of
Blood pressure consciousness
Temperature Movement
Skin color Abnormal nerve
response
Pulse
A direct extension of
the functioning of the
heart
Normal pulse rate for
adults
60 – 80 bpm
Normal pulse rate in
children
80 – 100 bpm
Abnormal Pulse
Rapid and weak Slow and strong
Shock Skull fracture
Bleeding Stroke
Diabetic coma No pulse
Heat exhaustion Cardiac arrest
Rapid and strong Death
Heatstroke
Severe fright
Respiration
Normal respiration rate for adults
~ 12 breaths per minute
Normal respiration rate for children
~ 20 breaths per minute
Rapid and shallow respiration is
indicative of shock
Blood Pressure
Normal systolic blood
pressure in adults
Males: 115 – 120 mm Hg
Females: 105 – 110 mm Hg
Normal diastolic blood
pressure in adults
Males: 75 – 80 mm Hg
Females: 65 – 70 mm Hg
Blood Pressure
High Blood Pressure
Systolic BP > 140 mm Hg
Diastolic BP > 90 mm Hg
Low Blood Pressure
Systolic BP < 100 mm Hg
Diastolic BP < 60 mm Hg
Temperature
Normal body temperature
~ 98.6°F (~ 37°C)
Core temperature is most accurately
measured at the tympanic membrane of the
ear
Changes in body temperature are reflected in
the skin
Skin: Temperature
Cool, clammy skin
Shock
Trauma
Heat exhaustion
Cool, dry skin
Overexposure to cold
Hot, dry skin
Disease
Infection
Overexposure to environmental heat
Skin: Color
Three skin colors are Red skin color
commonly identified Heatstroke
in medical High blood pressure
emergencies: Elevated body
Red temperature
White
Blue
Skin: Color
White skin color Blue skin color
Shock Airway obstruction
Insufficient circulation Respiratory
Fright insufficiency
Hemorrhage
Heat exhaustion
Insulin shock
Pupils
Pupils are extremely sensitive to changes in
the nervous system
If one or both pupils are dilated…
Shock
Head injury
Heatstroke
Hemorrhage
CNS stimulant drug
One constricted pupil…
CNS depressant drug
Level of Consciousness
In normal conditions, the we are:
Alert
Aware of the surrounding environment
Responds quickly to vocal stimulation
Abnormal levels of consciousness may result
due to…
Shock
Head injury
Heatstroke
Summary
May not be able to determine the type of
shock
Immediate management of shock is
universal
Provide reassurance and comfort
Maintain normal body temperature
In most cases, elevate the feet and legs
above the level of the heart
Case:
A 72 year old female is admitted complaining of
weakness, sweating and dysuria. Her temperature is
39C, pulse 130, BP 76/44, warm peripherally, lung fields:
reduced air entry bilaterally, oliguria, Hb 16 g/dl, WCC
27, PO2 8.2, Urine gram -ve bacilli, >105 organisms.
What is your diagnosis?
How would you classify this patients haemodynamic
status?
How would you manage this patient?
What is your diagnosis?
Gram negative septicaemia/septic shock
How would you classify this patients
haemodynamic status?
High output, low Volume, septic shock
How would you manage this patient?
1. Oxygen therapy / mechanical ventilation if
necessary
2. Fluid loading with colloid.
3. Adrenaline or noradrenaline infusion.
Case:
A 27 year old male is involved in a RTA.
He sustains a burst fracture of T2 with
complete neurological deficit below this
level. Fours hours following admission
his SpO2 is 85%, his blood pressure is
80/40 and his heart rate is 45.
How would you classify this patients'
haemodynamic status?
How would you manage this patient?
How would you classify this patients'
haemodynamic status?
Spinal shock, low heart rate, loss of sympathetic tone.
How would you manage this patient?
1. Ensure patent airway and adequate ventilation.
2. Oxygen therapy.
3. Adrenaine @ 1-10m /min