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The document discusses various aspects of poisoning, including types of poisons, their effects, and methods of detection and analysis. It highlights the vulnerability of certain populations to poisoning, the role of toxicology in understanding poisoning cases, and the complexities involved in determining the intent behind poison administration. Additionally, it covers the symptoms of poisoning, the importance of sample collection, and the variability in individual responses to toxic substances.
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esi, yes or moons membrane Sh 38 thse gra
‘vagina or penis.
About 3000 ofthe more than 12 million known che
fee more accidental and deliberate poisonings. Howes
"ios any substance ingested in large quantities can he tone
Gam sours f pons inclie dries hoes
F foultural products, plants, industrial chemical
ae poisons that eam
| poisoning ean oocur but cannot be identified. Probably, the
"tos poisonous substance in existence is plutonium, Rin, a
eT cant ol sce i loo x very pa
Poisoning is most commonly a ora
‘ ériminal attempt to commit murder, or suicide ora
“Sticdal gesture, Children, under the age of 3. are particularly
“Wulherable to poisoning, as are the elderly. fom confusion
their medications, hospitalized patients from
ion errors, and industrial workers froin exposure to
‘hemicals. Suicidal poisoning is now the most common
of killing oneself in advanced countries due to the ease
taining these toxic drugs. Paracetamol has now replaced
and aspirin as favorite methods of suicide
tal products such as paraquat, parathion and aceti
Re Ribber preparation are common sources of poisons
280
| proteins that cause
wat are delivered,
Pern venomous and poisonous. The de
“poisonous” are synonymous,
2c)
voxtion, for example by bindiig to a &
Jeen known to be symbolized by the skull
Biological poisoning
Contact or absorption of}
Impairment. Agents that act om
Paralyze in seconds or less,starves the body of energy
the synthesis of ATP. esas i
high concentration. of potassium 1p
‘execution of prisoners in parts of the wot,
stops the heart by eliminating the cell poy td
ser mc contraction. Such rapid reactions. ttl
fey
Most (but not all) pesticides are created to act ag
to target organisms, although acute or ess observable «
ean alo occur to non-target organism. inchad
Thiumans who apply the pesticides and other pi
“organist.
7A prison may ako act lowly. ‘This is known as chron
deoning and is most common for poisons that bioaccumulate
ofthese types of poisons are mercury and lead, Many
Substances regarded as poisons are toxic only inditwetly, Ay
{eatmple is “wood alcoho” or methanol, which is not poisonous
itself, but is chemically converted to toxic formaldehyde in the
liver. Many drug molecules are made toxic in the liver, and the
{gee variability of certain liver enzymes makes the tony of
‘many compounds difer between one individual ad the next.
‘The study of the symptoms, mechanisms, treatment and
Aiggnosis of biological poisoning is known as toxicology
Exposure to radioactive substances can procuce radiation
‘Poisoning, an unrelated phenomenon,
For some reason, a poison has an enduring, fascination.
Most People vem to be both repelled and attracted by it
B) Pesibly beeatie itis deadly and, at the same time, discreet. Its
Make those Of more obvious weapons, are not messy and
eral. is capable of
fanctions, or of placing
ate a 0 prevent the ont
‘the Revised Penal Code in
ya without intent to kil shal
oe a oe
A any injurious substances oe by
miantage of his weaknestes of mind 9
Se penalty provided for in Arle 268
ftisthe INTENT to kill or injure another
If the intention is <0) Hila
because of the administered poison, then
orhomicide, depending upon the presence or
qualifying circumstance
SIGNS AND SYMPTOMS OF POISONING _
‘There are specific symptoms and;
of poison. The following are general
Nausea, sudden vomiting,
seinures and hypotension
Vague abdominal dis
‘vomiting, constipation
pain,
Symptoms appear
apparently in4 Map onset of « neurological oF gastroinag
nz in perons known to be occupa
exposed to chemicals. Y
More often when a poison is suspected, th
doa toxicological examination with the taking ofa sample
from the deceased or in case ofa non fatal poisoning, from the
first step tp
Teing vietim, Samples from the latter are usually much eageg
factor of ney
Before any actual analyag
the complicating,
‘decomposition products is absent
‘ean be made, the sample must be treated in various ways in
‘onder to extract and purify the poison in it
Poisons ean be extracted using organic
‘ther or chloroform, or by the use of solid silica absorbents
vents such as
TOXICOLOGICAL TECHNIQUES USED TO IDENTIFY
‘THE PARTICULAR POISON
1, Chromatography. —This technique
‘arious compounds in a sample to identify a specific
feompound, Diflerent compounds pass on an absorbent
Medium at different rates depending on their different
ral compositions. In gas chromatography, wherein the
isheated to make it volatile, the molecule from the
compounds move through a long narrow tube of gst
toward a detection devise that recognizes the specific
separates. the
rn aoe
anc aspect which
ia hon according to its tome
fe getrometry ate the opether
vot a certain method of
matography’ is a crude sorting mel
iy improved with the concomitant:
Gretrometer. Actual identification ofthe
secnparing the results obtained with the
oon coc
3, Immunoassay.—This te
used, but the principle is that whem a
Hoo! circulation, this foreign body
will cause the body to produce a d
antibody will arrest the antigen and
antigen-antibody complex. The
complex is then consumed by the
1 be identified by im
antigen then c
ADMINISTERING THE POISON
How the poison has been
because it will determine whether the]Tn aid of the determination of the
ems during Is. the pong
‘and the moral circumstances maybe cons
tive embed wis
Betas the dan had partake.” Whar
tinal Evidence, 11th edition, pp 233-234)
-—Gyanile and arse are usually ingested through the
~ gnouth, while substances like heroin are often injected into the
flood. Some poisons such as snake venoms, are not poisonoys
“unless they enter the body through the bloodstream. Tha.
‘venoms, being proteins are simply digested in the mouth, if
‘taken by mouth,
410 this route of entry into the body ix the inhalation of
‘Substances which reach the hangs and pass from there into the
ss
Tnjecting drugs such as heroin directly into the
‘very effective way of introducing
drug taken that
bioavailability
on ae sero bioavel
feet. Heroin has 2e
ve
bioavailability of the d
oe ae
ia which is poorly absorbed, didn
‘Fp viet. then these points would be sig
line The forensic toxicologst therefore
quantity or dosage of the poison
METABOLITES
Metabolic activity usally aa
exereted
poisons and their exeretion, ‘The:
Metabolites. They’ are substances p
or transformation of the ingested
out of the body, usually in the uring,
easily, that it is detected as a m
than the drug itsel
Some poisons are however
immediately but are retained for
the body, like the Cannabis
‘examined in the blood by
ions are excreted simply by!
fingernails where they can do lilke opiates, ease therapeutic problems
doses need to be given to give an analgesie
Fiks of respiratory failure and death,
Darbiturates, Berwodiazepines and ye
group alll exhibit ge
| Aneyneracy is the opposite situation of Tolerance, 4
‘unall dose ofa substance or poison which may not be fatal
4 person without Idisyneracy can however be fatal in the
of the idiosyncracy phenomenon. The Peniciing
Heroin are examples of drugs which
‘TOXIC DOSE VERSUS FATAL DOSE
“Toxie dose means that smallest dose which is known to
‘Proice symptoms or disability. while the fatal dose is the
‘tallest amount or dose, known to produce death. There iso
exact dose that ean certainly cause symptoms of toxicity oF
death. The vulnerability of people to a toxic or fatal dose ®
‘leatly variable, One person may not react at all to one dose af
450mg Ampiciin, while another person with the same dose
_ ayshow sign of toxic ty or hypersensitivity reactions.
1LD50 or the minimum lethal
Dased on animal experi
ee
dose is merely
ments being
fh the heart, great vessels or Visceral
2 ke capabilities of the difeen t
vaepation time from the body i ao
von calculations oF extrapolations
pr nisleacing and should not be the only
the appropriate dose, Experience and sound)
important in the calculation of the
inonler to avoid a toxic o lethal dose,
SAMPLE COLLECTION AND STORAGE
of a criminal or court action, the samples
labeled and identified. The responsible:
ood samples from the veins, urine
uth, the esophagus, the
ete, must place the
vated tube or flasks,
the vietim’s name, address, date
Storage, the particular type of
Sc. the place or venue whereathe abel, nd mach a
ofthe samples must also be
“of the person to whom the samples Were gj
to the laboratory must be entered ig
das to establish continuity of the evidence,
samples must be taken only fm py
femoral veins or axillary veins. Blood sample
{ikem from the heart and great vessels or the jugiige
system maybe contaminated or may contain abnorm,
“false higher concentrations of the poison, compared tg
"the other areas of the veinous circulation. For mog
‘examination, 15 ml of blood is removed and placed in g
tube with a 5-10 ml of anticoagulant, such as EDTA,
jam oxalate or heparin. If alcohol intake iy
suspected. 5 ml of blood is placed in a sodium fluoride
tube to inhibit production or destruction of alcohol by
URINE—About 25.30 mi of urine is collected by
“aspirating the urinary bladder or inserting a uxinary
| catheter: No preservative is required. but if there is any
| delay in bringing the urine to the laboratory, a small
| amount of sodium azide can be aed
YOMITUS AND STOMACH CONTENTS —Vomitus and
‘other stomach contents, should be placed in a clean glast
HOF & plastic tube with a tight fitting lid. The stomach
Be opened at the lesser curvature in a
and allow the contents to gravitate towank
—" pti
.
laced into a
a nd oo
resting
LUNGS AND OTHER 0
eels, og ld
try inpeviod ST
roid the escape of veins Theta
telvent abuse can sls be Raina
vom, che Iver aaa
Se when utine ot a
Te whole iver i eet
HAIR AND NAIL CLIPPI
cut or pulled from the roots eam
Neutron Activation Analysis eat be
when the poison was administered
keratin, and the most recent
roots,
. INTERPRETING THE=
‘will depend upon the correctness op
fon. which 10 anchor his decixign the
‘therefore of the toxicological results ma
“Ina criminal act, the importance of an intention 4
injure matters mos: This canbe lite inthe King ill
oaage of the poison used
eau which the perpetrator of the crime intended it yy
What f the dosage that results to injury or death? tye
nove ix that there is really no fixed dosage, because «aig
Denon of ight build will succumb to much lower doses gf
order to achieve that ov
poison or drug that would have little or no effect on a lage
‘and healthier person. Alw the concentration of the poison gp
fhe metabolite can vary according to where in the citculatory
‘stem a blood sample was taken
Ifthe dead body is already infested with maggors, itis
tho wise to compare the concentration of the poison taken
foun the maggots and that from the dead body. Samples fom
© he urine can alo vary depending upon the state of hydration
(Of the vie, Recent intake of coffee or tea increases the
Nolume of urine since they are diuretics, Products of
decomposition from a dead body can also confi
Because they are alo poisons which can either neutralize
Weaken orstregthen th effets ofthe original poison
Mogphine ia stable compound that does not decompose
afer death. Morphine and diamorphine, te main active
of heroin have been given intentionally in ovet
vith two effets of pain ree and respiratory depresion
e the issue
Ampletamines, tke “Speed” and
feat examples of these =
patemic poisons. Speed Sea
eidence making the user mone
Methamphetamine is the most
in the USA and in the
rferes with the reuptake:
an is toxic to the Bs
with other drugs and or mix
Amphetamines, fatal heart attacks
presure so high that a blood vessel
causing stroke with paralysisand death, —
Hallucinogens include ISD,
rushroom). mescaline _(peyate)
mmethylamphetamine (DOM, STP)
Acid Diethylamide (LSD) is a very
a synthetic drug obtained from
ISD is very dangerous, ea
‘Schizophrenia, panie attacks:‘ingested by children and aduys
tho have a special fondness for gait
fof these wild berries. Symptoms of tt
Jhoarseness and drying of the skin. Thery. opine
Pad ultimate respiratory falure, 8
yoni, a drug found in the deadly nightshade
(dara stramonium) and Henbane (Hyoy. gy
causes delium and renders the user incapable of ig
tnd rewoning. Hyoweine under the more comme
‘Cocaine from the dried leaves of Erythiroxylim coca, igg
‘nerve stimulant and can kill by over stinualating the
It is similar to heroin and other narcotics. Cocaine ie
the cocaine with bal
positive for
use, though he had not actually used cocaine.
TRYCHNINE is a
ant and convulsant drug, which comes from an Indian
€ called Strychnos nux vomica. The symptoms from
ne poisoning are almost that of tetanus with stiffening
Hrigilty of the muscles in the chest, while that of tetanus
paw muscles stiffen most noticeably, with a risus
fin of the facial contracted muscles. Paralysis of
oblongata causes death. It causes excruciating
Me the vietim dies, The fatal dose is 30-60 mg althougl
48 variation in the fat
ao
al dose in a particular viet
fun!
ope)
‘of the poison in the,
Aeonite is another
jaitum napellus ct
Aah the Greeks called the “Queen,
de: tingling ensation inthe
” ‘The limbs become weak, with
and hy’
mushroom species are also. poisonous
timetting and death. The death eap isthe
mushroom, which is the frequent cause off
Palocybe semilanceata is a hallucinogenis
cighty species of this genus prods,
hallucination.
3. TRANQUILIZERS—The analgei
narcotic drugs are among the eommonest
suicides and they are the tranquilizers
doses can cause death after two to thre
falure and renal tubular necrosis:
overdoses of 20
paracetamol is combined with D
Simultaneous presence of bi
spileptics or the presence of eh
‘worsens the situation. Blood
tugliter are likely to produce
ees 41. eee~ Among the tranquilizers, the hypnotic Barbitaratey
‘most dangerous. Barbiturates are often mixed
‘mixed in milk, are reddish like red skin berries.
fhe short acting barbiturates can also cause death with
‘about thirty minutes,
The blod levels found in fatal poisoning vary between
about 5 and 50 mgfiter, mgflter The
intermediate acting barbiturates include amylobarbitone
(Amstal) pentobarbitone, allobarbi tone and butobarbitone
where the mean fatal evel is around 25 mg/liter, or ranging
fiom 10-Tmgliter. The long acting barbiturates, ike
Phensbarhitone, phenytoin and barbitone require higher
Bod levels of 120 mgfter to cause death. In autopsies of
fatal barbiturate poisoning, there are p
‘ofthe gastric mucosa,
Bee Black ngs and cyanotic lividity due to central
9M pstor fare which isthe mode of dash
Setbibitale blisters develop in 6% of patients receiving
esol batbiturates in areas where two ekin surface
Beer Nother, like the inner thighs ‘The
han average of
positive signs of erosion
al signs of marked congestion with
wit
oil the later enhancing the effect of the barbtaat
i lose needed for a fatal
greatly reducing the total di Fesult. One
fgam of barbiturates can kiln soconds or minutes, Sosa
short ting barbiturate, has been wsed to poison babie org
take then skap. The throat of babies poisoned with sco
‘The antidepressant,
rs causing great agitation
i :
ae
Oe teal
‘othms, polyuria, coma and d
ood of 2 mmoVliter and above ean
Narcotics ar
conciousness. Opium is the dried juice
{Papaver Somniferum), where codeine
extracted. Heroine is derived from
substances which are found in the opium
the plant’s seeds are Thebaine, Nareoting
The symptoms of opium poisoning ar
tocoma and heavy sweating, Thebaine
very quickly. Opium poisoning eases thew
temperature, but its most dstintive
“pinpoint” contraction of ‘Uke pupil
“pinpoint pupils” positively shows
donna drops placed in the eyes ean p
Pinpoint pupils
A “cutting agen
barbiturate, used to dilute opium OF
emeral, the fatal dose of morphine:die with doses of only 10 mg,
from the plant Cannabis Sativa is oo
(Mary Jane). Cannabis is commonly tly
a igaretes joints) made from the tem al
tops of the dried plant cannabis sativa. 1
ingredient of marijuana is tetrahydrocan
| THC occurs in many variations the hai
Aelia 9-THC, Dronabinol is, Deta-9-THC. Dronabing
in research and sometimes used to treat the nauseg wl
‘vomiting associated with cancer chemotherapy. Tt eg
ismeicnal and les addictive than alcohol
Paralytic poisons include the toxin Contine found in the
Teaves of Hemlock (Conium Maculatum) the poison which
‘was used to execute the philosopher Socrates. Coniine
Dparalyzes first the legs, then the rest of the body and
‘ultimately leads to respiratory failure and death, Nicotine i
not widely used as a poison, th fatalities have
‘courted due to its use. ‘The purified toxin is used in various
inseticides and pesticides. Three or four drops of pure nicotine
Killin a short time. The poison can be absorbed by mouth, by
inhalation, or through the skin.
Around the body during smugeling
effects as has the tar and
stoking.
4. HYPOGLYCEMICS—This potent hypoglycemic drug
Aosin, has been used repeatedly in, homicide and in suicide
AES HI suspected, itis an effective murder, homicide oF
method. Normally the body maintains the level of
A sugar within 70 t0 110 n
‘sugar levels,
gh ma
obacco leaves wrapped
ave caused serious taxi
mnants of pipe and cigarette
per deciliter of blood. Law
NE pees on 2 the hod
5, CORROSIVE AND METALLIC
yoo are used in suicides, homicide,
Tents of torture, Caustic substanes i
‘well as the salts of heavy metals
action on the tissues,
mouth, esophagus, and stomach, Some
pives containing cause sisi
[eal cleaners and dishwater deta
imay eat through the wall of the «
‘The damaged stomach oF esophagus
werk or more after the poisoning, posi
events as vomiting or severe eougl
disinfectants and antisepties inllocal
orearbolic acid and related compounds}
Sicide poisons. a
‘wallowing phenol results
mouth and the digestive trate
‘weet smell, There are burns
Death is due to. Central Ne
reralized destruction of theslike Epeom salts and have been
streaked with hemorrhagic neerosig
‘contains black altered blood acid hematin,
fonalate crystals adherent to the ulcerated mug
eT att faves, reruking into hypocalet
sulting calcium oxalate precipitated crystals are feat
fi the Kidney proximal convoluted tubules causing neergg
‘of the cells therein,
UAmenie substances are now most often used as poison in
Mesias a popular poison for wiih g
agnostic ton wos devised called the MARSH TEST. Thang
BP ive tate, which can be easily masked by the fend
BRMMEEN ff eciinitered. Areenic isn't poisonous a
the metal itself, but only its compounc
et iets arseniies like copper, sodium
About 200mg-30mg. of arsenious oxide is needed for acute
fatal toxicity. They interfere with cellular respiration by
Pombining with sulphydryls in the mitochondrial enzyme,
‘The vascular endothelium isa specific target that accounts for
Wt lesions of increased permeability, tissue edema and
Hemorrhage. The signs and symptoms of arsenic poisoning
Have ofien been mistaken as a natural intestinal disease. In
Ase Pobning vomiting, often blood speckled, i one ofthe
‘of symptoms, followed by intense stomach pai
thirst, nausea, cramps, lose of weight. a feeling of
‘and constriction in the throat. There is dehydration
like arsenious oxide
eaning metalang |
a leaching fot onthe a0 f thea
(erythromelalgia) are
ost abundant element.
ee
eae
Feed
sol mo The eal
forseveral years after its administration,
cul ompound cat oa
wl ground water, as
homicide and accident
called “tartar emetic.” Antimony found
ofcooking utensils have resulted int poi
of 150 mg can prove fatal, Antimony.
the treatment of Bilharzia,
Mereury, in the form of met
hospitals and clinics as antisepties
‘industrial poison that has resulted
mercurial poisoning, there is @
Gastrointestinal manifesta tions
and arsenic poisoning. Renal F
han i
marks of chronic mereurialor plumbism is usually 4
Fes chides and a
dn adults maybe permanent. The risk or pes
though unpredictable, i great at high blood loygh
fildren, symptoms start with several yoga
: fand decreased play activity. More soe
mptom abruptly oeeur and worsen Over 1-5 dayy,
Pele forceful persistent vomiting. uncoordinated walk
eimures, confusion, sleepiness and finally uncontrolahie
tczurs and coma. The symptoms of brain damage are eatua
Fnainky by swelling of the brain. Stopping the exposure doo,
fot remove all the risks of brain damage and
feded. In adults, a characteristic sequence of sy mptorns may
Gevelop over several weeks or longer: personality. changes,
Theadaches, a metallic taste in the mouth. poor appetite and
Wague abdominal discomfort ending with vomiting,
Gxetipation and crampy alvlorinal pain. Brain damage i
rare in adults.
Thallium is used as a rat poison and is widely used in the
ae In acute thallium poisoning, symptoms
fabominal pain and vorniting. Hair loss is a major sign after
fortwo weeks fom thallium intake. nthe succeeding days
ests fon and pyc symptoms appear: At
there are widespread non-specific degeneration in the
lives, Kidey, brain anther sans
Poisoning, causes diarshea, vomiting, high white
‘count and high blood glucose level. The symptom
cur in the following stages
serious. 4
Stage 2—Oceurs within 10-14
‘misleading improvement
to 24 hours
Occurs between 12 and
“and shock develops. Blood;
land test indicates liver
drowsiness, convulsions and;
Stage 4—Oceurs after 2 to 5 weeks.
‘as intestinal obstruetion,
Stage
6 AGRO- s
Insecticides have been used widely in eon
destructive pests, vermins andl in
kilers have greatly inereased
Pesticides and Tnseoticides,
fompounds kill insects and pest by
enzymes and the most toxie i
like, Malathion, Dithion, D
TEPP are also very poisonous
seidentally or by suicide.
‘The Organo-Phosphates“Dieldrin and Deophane (nit
xtemive povoning 10 people and wid ny
mista body fat but are not a8 toxic as the phos
HERBICIDES (WEED-KILLERS)—Paraqust (Gran,
ery poisonous when swallowed. This concentrated
mistaken asa drink and taken accidentally. Tt has ge
sed in aiid caves. Weedol andl Diquat are herbicides thy
ils been causes of serious poisoning. ‘They are oo
the mucosa of the mouth, pharynx, esophagus and
ei, Inthe liver, centrilobular necrosis and tubular damage
resulting hepatorenal failure have ensued in the frst few day
the intake, In the hmgs, manifestations of the Adult
i Distress Syndrome occur with Hyaline membrane
The alveoli are filed with pneumocytes leading to
8. GASEOLS POISONS—Accidental deaths have oocuned
suppl with gas produced from coal. Car engines emit
Garhon Monoxide (CO). Diesel engines produce: kes 00.
Monoxide has also been used by suicide victims while
their ar, with the engine on,
from the car exhaust inserted into the car window.
46% applanees and heating systems can procuce CO
Ba eeiny Kill whole families as they sleep in @
Saravan. A buming house or a building with buring
Aumitures and fabrics are good sources of CO. Strong
from a Yeak in a laboratory cvlinde
ie
se co may dic even a
Saturation. Tt must be
‘variable depending upon the age,
sibility of the victim. The
during life are surprisingly similar to,
its known that drivers are overcomed
tkakng into the interior of the ear because
Drives accused of drunkenness il
poisoning as a cause of their condition, but
pence of carboxy-hemogloin in the bod
truth.
Internally all the organs ane pink
carboxyhemoglobin and myoglobin,
common. In the brain there is bilateral eystie
the basal ganglia with parkinsonian
cerebral hypoxia of €O- poisoning
damage ‘
CO poisoning can be detected |
In optical deteeti
the spectrum of earboxy
geen segment,
The measure of CO saturation in opti
by the distance by which the aia: oa
wr the liberation of CO by Cy
. Mowe mor ely han Ca
DIOXIDE isa natural gas, relatively ine
‘concentration in the atmosphere
{C02 has no poisonous or accumulative
can kil, with mininsum fatal concentration, gp
and the high concentrations of 64.99
ding sudden death, When death is rapid with no vaso
it ean be due to vaso vagal reflex, triggered by q
stimulus,
C02 is often present in industrial sites and in places
‘where explosions or fires have just occurred. Its high
‘concentration inthe langs prevents the expulsion of CO2 fom
‘the body, so that respiration is hindered. Three (3) percent in
"the atmosphere will eause headache, drowsiness. giddiness and
“general weakness. In anesthesia, deaths have occurred from
‘oxygen cylinder becoming empty whilst commonly
eted toa still functioning carbon dioxide cylinder given
jon oceurs and can be fatal.
AMMONIA gas poisoning though uncommon, results in
eouphing pulmonary edema and bronchopneunon
= Permissible concentration is only 100 parts pet
Te has been used in assaults, homicide, murder, and
iby throwing the gas directly into the eyes and face #@
iti,
she
efor ke 20 mites to kill and
may Gyanide by inh
fearon oxide, Mocks the up
atthe blood Hence an unstable
‘eetater has bright sare color
Pe xin of those who die of eyanide
vy organs sone ike bitter almond,
fit or dark red. If eyanide igs
anach lining will be deep red o black
femorshage in the rugal folds,
9, HALOGENATED
atoms in these Hydrocarbons have
in the aliphatic chain of the
resulting substances have been sed
de dustry and medicine,
anesthetics have been inhaled int
anexthesiologists, with its pernicious
resulting to hepatic cell damage
strong fat solvent injuring the body
intocontact with through ingestion,
METHYLENE
‘wftigeration has caused many:
from a defective pipe system, Pro
fan result to a staggering
disturbances,vm skin contact, it causes skin blistey,
‘the body. muscular incoordination, Ataris
gand renal tubular necrosis may develop >
N TETRACHLORIDE is also used ‘
ecient
eel ners and iver faire by inhalant
a aneti ‘of possible
enor or more controversial ex
TETRACHLORETHANE is @ plasticizer used in fig,
‘and artical pearls ete. It is more toxic than ¢
“Tetrachloride, being nine times more dangerous. Liver neerg
and extremity polyneuritis have resulted in the vietims, > ee
10, GASOLINE AND KEROSINE—Every year, many FDA believes aspartame
elildren age five (5) years and below are poisoned by dietary doses
Swallowing petroleum distillates, such as gasoline and
Kerosene, Small quantities of these liquid can flow easly
getting into the lungs and damage them directly. The
symptoms affect chiefly the hungs, intestines and brain, Lang
{inflammation or Pneumonia can cause death in twenty four
hours, A chest X-ray isthe sin
test. Phe
Within 68 hours in 90% of the people who develop
[pneumonia asa result of gasoline and kerosene poisoning. |
Ti. ETHYLENE GLYCOL—is the most toxic and most |
widely available of the Glycols. Drinking more than about | ve
100-200 mil is fatal, resulting to acute renal failure. Glyeol i= in
5 fastroenteritis caused. by
fonvered to oxalic acid, with the presence of fan shaped | Graney caused BY A
Sree of calcium oxalate in the kidney tubules aM] nausea and vomiting, mild
interstitial tissues. Liver damage also occurs abdominal discomfort. Body
Alectrolyte losses results into
‘Saccharin) have been
neurotoxic (however these
# Asbestos—a widely used
‘causes mesothelioma and other
the respiratory tract.
Be
reactions).
Carbon tetrachloride (J
extinguishers).
develops in two (2) hours in severe ca
12, MCOTINE—The poison is absorbed by inhalatiom
IPRs patristic, ov vce sve cxin. 0g:5 OF COMMON FOOD POISONING,
infection of the small intestine,
‘brio Cholerae. It is spread by i
pple, ‘The small inteatines recrete
aunts of fide rich in minerals and salts, Out
I dering the warm months, though epidens
. nyreeanon affecting all ages. Natural immunigy a
Geel in endemic ares, Fewer than one percent of gn
Arh recive prompt adequate Did replacement i
than 50% of those untreated die of severe chole
B. Campylobacter poisoning —This is caused by dri
contaminated water,
eating undercooked poultry and meat,
be contact with infected animals. Mostly the bacteremia
foaum in people with existing disease such a diabe
canoe. Diarrhea maybe bloody with fever of 100 10.
. severe abdominal cramps and pain.
, Staphylococcal food poisoning —Poisoning. from eating
food contaminated with the
into diarhea and vomiting, Food handlers with any
aphylococeal infection, such as boils or impetigo, skia
infections should refrain from distributing or selling food and
Adrinks. Usually other people who ate the same kind of food
from the same food handler or restaurant are also afflicted.
Severe fluid and electrolyte loss can cause hypovolemic shock
Symptoms last for about 12 hours or less and recovery #
Usually complete.
By
phylococeal toxin, resulting
com pave been responsible in
rar of the Botulinum
i gant to eat and can survive bo
weerect_ problem in botulism ix
‘eepiratory failure and death,
FE, Clostridium Perfingens Food
most common cause foe
fre or mill, with
tun shock. Diagnosis i eonfiemed by:
foe dostridiuun perfringens
F, Travelers's Diarthea Calle
Trista itis characterized by dian
cccurring frequently among travelers
toxins and. viruses like the Norwalk
causing Traveler's diarrhea, Allfo0d
carbonated beverages or boiled
cubes from boiled water is
‘uncooked vegetables should be
G. Mushroom or Toadstoal
of Inocybe and Clitoeybe, eatHH. Sid poioning—Poivoning AWC 10 one of ay
thre fh toxine- Ciguatera, Tetraodon, or Histamge J. Contaminant ,
poisoning occurs after eating any of the more thay | wed or sprayed with arsenic,
4dapecies offs from the tropical refs of the Pac | aa quid served in lead glazed
he West Indies and Florida USA. The fish accunnlates she seium-lined containers may
tonins produced by dinoflagellates and other micro organiany ergs
Jptho sea, Larger fishes are more toxie than the smaller one Tine een
‘Mos fish processing do not destroy the accumulated toxingin ode oa
ithe body constitution ofthe fish. Abdominal cramps, nausea, es atti
‘Yomiting and diarrhea oceur two to eight hours after eating of pana 1 ae
he symptoms last for 6 to 17 hours, Later
ee a prvduces facial pressure, ehest
Symptoms, may include itchiness, pins and needles sensation, Fe tout hee
Treadache, muscle aches, a reversal of hot and cold sensations, _
‘and facial pain. In Tetraodon poisoning, death may result
Ey sta pene loarinc posing PHILIPPINE LAWS ON POTS
Mackerel, tuna and blue dolphin, occurs when the tissues of Section 755, of the Revised:
the fish break down due to improper handling oF that: “Every person who
fllowing violent poisons to Wits
Aeterioration, producing high levels of Histamine toxins
Histamine causes nausea and vomiting, stomach pain and phosphorus, corrosive sublinmatey
“uiticaria a few minutes after ingestion. There is ako other eyanide, atropine, cocaine,
immediate facial us oftheir salts and all other po
IT Red Tide poisoning —From June to October in the oi ia i
‘ocean and the New England coast, the waters contail = containing hydro
fantial number of dinoflagellates producing a red ct bane (nitro benzene).‘sich others a8 containing leas
sugans of pium per ane hung Soy
to the ounce) shall make op vt Sty
(ovo aig
ns rpok kept for the purpose of recording the tt
mimentey stating the date of each gale «Shot
yurehaser, the name and
Pe address of the pure! rd uant
if poten la she prone for which Ht as ae a
I before delivering it to the purchaser, 14 prions, but no prescription
oles auch poion 10 any person without saree fontaine a daneuns Tea
ar that such person is aware ofits poisonous chant consulting the Preciee
tia thatthe poison isto be used for a legitimate Purpose
Teall ffx to every box, bottle or other package contig
dangerous or poisonous drug, a label of red paper
ch hall be printed in large black letters the word “poign wet preceding sections shall be kept in a
Ted a vignette representing a skull and hones, elgg proved in every pharmaey carrying ch
Gaivering it to any penon. Books kept for the purpoe of re retail trade: and the same shall be kept
froonding the sale of poisons shall be open at all times tothe when not in ws
inspectors of the Board of Pharmaceutical Examiners, and of
Ihealth offices or officers of the law, and every’ book shal be
reserved fr at least five years after the last entry in ity hae
been made.”
Section 756 of the same Revised Administrative Cade
fal provides that; “Every person who dispenses, sll or
dalvers any aconite, belladonna, cantharides, colehicum,
onium, cotton root, digitalis, ergot, hellebore, henbants
Phytalaca, strophanthus, oil of tansy. veratrum viride, or
their pharmaceutical preparations, carbolic acid (phenol |
shloral hydrate, chloroform, creosote, croton oil, mineral ened
ids oxalic acid, paris green, salts of lead, salts of zinc, tart
matic, white hellebore, or any drug, chemical or preparation
PWlich according to standard works of medicine or materi
Iatica is lable 10 he lie
Further, Section 757 of the same!
de provides that: “The poisonous
Confirmed poisonings:
* Bhopal Disaster—An aoei
| a from 2 penta
| 2.000 people and injured
destructive to human adultavetie
homewer, ac
+ Georgi Markor— Assassinated in London with yin memoir ais
‘eSoerates—Acconfing to Plato, iled by dings poisones
Heallck (water hemlock, not hemlock the even
tree)
© *lan Turing—Apparently committed suicide by
painting an apple with Cyanide and taking a bite,
Viktor Yushchenko —poisoned with dioxin
the Ukrainan elections Ta
‘Suspected or rumored poisonings
Yasser Arafat—Arafat reputedly died from liver
Ginhosis, which may be a consequence of chronic |
aleohol use or poisoning. Some Arafat supportersfeel |
itis extremely unlikely that Arafat habitually used
aleohol (forbidden by Islam), and so suspect
Poisoning, possibly by the Mossad. (Note that
cimthoss is not necessarily
indeed any poison.)
aused by aleohol use, oF .
*Napoleon Bonaparte—some claim. he was killed by
Petesie on his staff with arsenic.
‘inconclusive,
Evidence i |