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Glycolysis and Gluconeogenesis Overview

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merin martin
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30 views1 page

Glycolysis and Gluconeogenesis Overview

Uploaded by

merin martin
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Dirty Medicine Glycolysis

Glucokinase Hexokinase
LOW affinity HIGH affinity
HIGH Km LOW Km
Acts as glucose sensor Basal glucose metabolism
ONLY uses glucose at high conc. Glucose ALL tissues
Liver & pancreatic b-cells

Glucokinase Hexokinase

= Rate-limiting Enzyme
Glucose-6-Phosphate

ATP
Citrate
&

Fructose-6-Phosphate
Insulin
Phosphofructokinase-1
Glucagon
-2

~
se
ina

&
tok

Fructose-1,6-Bisphosphate
uc

AMP
ofr

!
ph
os
Ph

&

As
Phosphoenolpyruvate
Fructose-2,6-Bisphosphate
Pyruvate kinase

Pyruvate

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