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Cipro, Nicotine Patch, and Warfarin Overview

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0% found this document useful (0 votes)
11 views10 pages

Cipro, Nicotine Patch, and Warfarin Overview

Uploaded by

cristyn.carino
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Cipro (Ciprofloxacin hydrochloride) Contraindication/Precautions:

500 mg tablet - Hypersensitivity to cipro & quinolones


- Use caution if pt is pregnant, breastfeeding,
Alternate name: Ciprofloxacin Hydrochloride have a history of seizure, renal and hepatic
disease, stroke, CV disease, geriatric, QT
Frequency: 1 tab Q12H prolongation, hypokalemia, colitis
Class: fluoroquinolone antibiotics Medication Interaction:
Action: Stop bacterial growth by inhibiting DNA - Metformin/sulfonylurea: lower & control blood
gyrase sugar level
- Warfarin: ↑ risk of bleeding & bruising
Use: treat bacterial infections (typhoid fever, - Dairy product: ↓ cipro absorption
plague, infectious diarrhea, UTI, nosocomial - Magnesium, aluminum, calcium, iron, zinc: ↓
pneumonia, inhalation of anthrax, gonorrhea) cipro absorption (antacids)
- Painkillers
Common Side Effects: - Medication affects heart rhythm: side effect ↑
- Nausea
Nurse Consideration:
- Vomiting
- Assess pt for S/S of infection (including
- Stomach pain
characteristics of wound, sputum, urine stool,
- Heartburn
WBC> 10.000/ mm, fever, obtain baseline
- Diarrhea
(before & during)
- Vaginal itching and/or discharge
- Assess for Stevens Johnson syndrome,
- Pale skin
anaphylaxis: rash, dyspnea, pruritus, chills,
- Unusual tiredness and sleepiness
fever, joint pain. Have emergency equipment
Serious Side Effects: (epinephrine & resuscitation)
- Serious skin reaction: rash, swelling of face, - Monitor QT Prolongation
lips) - Check for CNS symptoms: headache,
- Severe diarrhea (watery- CDAD- [Link]), dizziness, fatigue, insomnia, depression,
nausea, vomit, excessive sweat seizure
- Heart rhythm change: fast or irregular - Check for overgrowth of infection: fever,
heartbeat, severe dizziness, feeling faint, redness, pain, swelling, draining, rash,
lightheaded, chest pain, trouble breathing diarrhea, change in cough, sputum
- Seizure - Monitor: AST, ALT, CBC, Hct, bilirubin, LDH,
- Pseudotumor cerebri alkaline phosphate
- Toxic epidermal necrolysis
Times:
- Anaphylaxis
- Onset: begins working rapidly
- Stevens- Johnson syndrome
- Peaks: 1-4 hrs.
- QT prolongation
- Durations: up to 24 hrs.
- Yellow skin or eyes

Dosage Safety: Patient Education:


- Usual dose depends on infection - Do not skip doses and finish treatment even if
- UTI: 250 mg Q12H for 3 days pt feels better; when missed, do not double
- Other infection: usually 500 mg- 750 mg and dose
days depends on the infection - Do not crush or chew the extended release
- Comes in tablet of 100mg, 250 mg, 500 mg, - Can cause skin sensitivity so protect skin and
and 750 mg avoid sun exposure
- Extended-release form (Cipro XR) in 500 mg - Drink plenty of water to prevent
& 1000mg doses crystalluria
24 HR Nicotine 0.292 mg/hr. Contraindication/ Precaution:
transdermal patch - Hypersensitivity
- Pregnancy & breastfeeding
Alternate name: Habitrol
- Diabetes mellitus
Dose: 1 patch - Dysrhythmias & coronary disease
- Impaired kidney and liver function
Class: ganglionic deterrent - Continued smoking
Action: release nicotine through skin, helps - Peripheral vascular disease
reduce cravings and withdrawal symptoms - Hyperthyroidism
- Peptic ulcer disease
Use: provide source of nicotine during controlled
withdrawal from cigarette smoking. Medication Interactions:
- Bromocriptine, cabergoline: ↑ vasoconstriction
- Adenosine: ↑ effects
Common Side Effects - BuPROPion: ↑ B/P
- Dizziness, headache, nausea, vomiting - Insulin: ↓ effect
- Diarrhea - Cimetidine: ↓ nicotine clearance
- Redness or swelling at the patch side - Adrenergic antagonists, beta blockers: ↑ effect
after smoking discontinuation
Serious side effects - Ergots: ↑ vasoconstriction
- Severe rash or swelling
- Seizures
- Heart palpitation- rapid, pounding, irregular Nursing Consideration:
heartbeat (tachycardia, dysrhythmia)
- Assess for withdrawal symptoms: headache,
- Difficulty breathing
fatigue, drowsiness, restlessness, irritability,
- Hypertension
severe cravings for nicotine products before,
- Difficult breathing, wheezing
during, and after treatment
- Assess for nicotine toxicity: GI symptoms
Administration: (nausea, vomiting, diarrhea), cardiopulmonary
symptoms (decreased B/P, dyspnea, change
- Wear gloves and wipe with alcohol pad and in pulse), weakness, abdominal cramping,
place in upper chest, upper arm, shoulder, headache, blurred vision, tinnitus,
back or inner arm. hypotension; product should be discontinued
- Avoid putting patch on areas of irritated, oily,
scarred, or damaged skin
- Press firmly place for ~10 secs. Patient Education:
- Choose new spot on the body every new
- Instruct patient to apply once a day to a
patch
nonhairy, clean, dry area of skin on upper
- Don’t wear two patches at same time
body or upper outer arm; to rotate sites to
Times: prevent skin irritation
- Onset: Rapid - Instruct patient to stop smoking immediately
- Peak: 30 mins. when beginning patch treatment
Preparation & Dosage Safety: - Teach patient signs of toxicity: nausea,
vomiting, diarrhea, headache, dizziness,
- If smoke more than 10 cigar a day: week 1- 4: dyspnea, hypotension
21 mg patch; week 5-6: 14 mg patch; week 7- - Caution patient not to exceed the prescribed
8: 7 mg patch. dose
- If smoke less than 10 cigar a day: week 1-6: - Discontinue if patient is unable to stop
14 mg patch; week 7-8: 7 mg patch smoking after fourth week of therapy
Warfarin Sodium 4 mg oral tab Contraindication/Precaution:

Alternate name: Coumadin - Pregnant & breastfeeding


- Hypersensitivity
Dose: 1 tab - Pt w/ liver disease
- Pt undergo surgery (brain, eye, spine)
Frequency: Daily
- Use caution if pt is Asian, have diabetes,
Class: anticoagulant; coumarins indwelling catheters
- Hypertension
Action: decrease ability to clot by preventing
synthesis of coagulation factors Medication Interaction:
Use: prevent clotting (blood thinner); prevent - Antibiotics: ↑ warfarin level
venous thrombosis, pulmonary embolism. - Antifungal: ↑ risk of bleeding
Reduce risk of stroke and heart attack - Anti-seizure: clear warfarin faster and ↓ INR
(especially in pt w/ heart condition) - Phenytoin: ↑ toxicity and ↑ warfarin effect
- Statin and propranolol: ↑ warfarin level and
risk of bleeding
Common side effects: - Blood thinner (Plavix): ↑ risk of bleeding
- Vit K: ↑ vit K= ↑ warfarin
- Bleeding, bruising, rash, nausea, vomit,
- Alcohol: (binge: ↑ warfarin & ↑ risk of
diarrhea, chills, itching, change in taste
bleeding); (everyday drink: ↓ warfarin level)
Serious Side effects:
- Severe bleeding: feeling faint, lightheaded,
-Nursing Consideration:
dizziness, vomiting blood, bloody or dark-
colored stools, severe pain or discomfort - Monitor blood studies: hct, PT, INR (make
- Calciphylaxis (Ca build-up in blood sure blood is not too thin/thick)
vessels): skin discoloration, skin sores, - Monitor B/P
painful lumps in skin, skin infection - Monitor for fever (TEMP) & skin rashes
- Hematuria & Hemorrhage - Ask the patient for abdominal or back pain,
- Anaphylaxis severe headache, confusion, seizures,
- Purple toe syndrome hemiparesis, and aphasia because they
- Liver damage indicate hemorrhage.
- Check the patient for excessive bleeding
from minor cuts and scratches. Assess their
Administration: gums for erythema and gingival bleeding.

- Check hct, PT, platelets, INR Patient Education


- Avoid alcohol
Preparation & Dosage Safety:
- Withhold med during active bleeding (mens)
- Initial: 2-5 mg PO per day; then adjust - Instruct to carry/wear emergency ID
based on INR level identifying product taken
- Inform pt about limit intake vit K food
Time: - Take warfarin (Coumadin) exactly as your
- Onset: 12-24 hrs. provider tells you.
- Be careful with high-impact activities or
- Peak: 1/2 – 4 days
sports while taking this medication. Advise to
- Duration: 3-5 days use soft toothbrush. Avoid IM injection.
Pilocarpine hydrochloride 2% Administration:
Ophthalmic solution - Tilt head back, pull lower eyelid, place drop
in conjunctival sac
Alternate name: Salagen - Gently close eye and apply gentle pressure
inner corner of eye (1-2 mins). Try not to
Dose: 2 drops OU
blink or rub eyes
Frequency: Q6H
Class: cholinergic agonists
Action: ↑ smooth muscle tone, contracts Contraindication/ Precaution:
pupillary and iris sphincter muscles, & induce - Hypersensitivity
miosis - Caution if pt is pregnant, breastfeeding,
Use: kidney and/or liver disease.

- treat glaucoma and ocular hypertension Times


by allowing excess fluid to drain from eye (↓ - Onset: 10-30 mins
fluid in eye= ↓ eye pressure). - Peak: 1 hr.
- Treats presbyopia by reducing size of pupil - Duration: 4-8 hrs.
which helps see objects up close. Nursing Consideration:
- Check for contact lenses, discharge
- Assess for redness and pain
- Long term use: CBC test (to check kidney,
liver function, and electrolytes)
Common Side effects:
- Temporary blurred vision
- Chills
- Diarrhea Client Education:
- Excessive swelling
- Flushing - Inform pt about S/S like temporary mild
- Headache burning, stinging and blurred vision
- Mild burning, stinging - Teach pt about proper use of solution
- Bitter taste in mouth - Advise pt to use caution with night driving
and when performing dangerous activities in
Serious side effect: low lighting
- Inform pt about possible hypotension
- Allergic reaction: skin rash, itching, swelling
of face, lips, tongue, throat
- Changes in vision Medication Interaction:
- Fast or slow heartbeat
- Decrease B/P - Carbonic anhydrase inhibitors
- Sulfonamides
- Thiazide
- Tegafur
- Medication for B/P and heart problems
Ondansetron 4 mg Disintegrating Oral tab Contraindication/Precautions:
- Hypersensitivity
Alternate name: Zofran - Pregnancy & breastfeeding
- Children
Dose: disintegrating tablet - Pt w/ phenylketonuria
Frequency: Zofran - QT prolongation
- Torsades de pointes
Class: antiemetics; 5-HT receptor antagonists Medication Interactions:
Action: block serotonin at 5-HT3 receptor site to - Apomorphine: increased unconsciousness,
hypotension: do not use together
prevent nausea and vomiting
- CarBAMazepine, phenytoin, rifampin:
Use: prevent severity of nausea and vomiting decreased ondansetron effect
after chemotherapy or surgery - Increased QT prolongation with other products
that prolong QT
- Serotonin- increasing medication (SSRIs,
SSNRIs), MAOIs, tricyclic antidepressants:
Common side effects: Increased serotonin syndrome, monitor for
- Headache symptoms
- Constipation
- Weakness
- Tiredness Nursing Considerations:
- Chills - Assess for absence of nausea, vomiting
- Drowsiness - Assess for hypersensitivity reaction: rash,
bronchospasm
Serious side effects - QT prolongation: monitor ECG in those with
hypokalemia, hypomagnesemia, cardiac
- Allergy: Rash
disease and those receiving other products
- Severe dizziness
that increase QT
- Hypoxia
- Serotonin syndrome: occurs when other
- Fast, slow, or irregular heartbeat
products are given that increase CNS or
- Change in heart rhythm (QT prolongation) peripheral serotonin levels; agitation,
- Serotonin syndrome (↑ serotonin, agitation, confusion, dizziness, diaphoresis, flushing,
confusion, sweating, shaking) tremor, seizures, nausea, vomiting, diarrhea,
product should be discontinued
Patient Education:
Administration: - Instruct patient to report diarrhea, constipation,
rash, changes in respirations, or discomfort at
- Oral disintegrating tab: Remove strip from insertion site, serotonin syndrome
pouch, place on tongue, and allow to - Teach patient reason for medication and
dissolve, drink water expected results
- Avoid alcohol ( ↑ drowsiness)
Dosage Safety - Monitor improvements in GI symptoms
- 4 mg = 1 disintegrating tablet (decreased nausea and vomiting, increased
- Chemotherapy induced nausea: 8 mg PO appetite)
- Monitor EKG, potassium, and magnesium
Times: levels due to the potential for dose-dependent
QT interval prolongation
- Onset: 30 mins- 1 hr.
- Peak: 1.5- 2 hrs.
APAP (Acetaminophen) 650 mg Rectal Medication Interactions:
- Alcohol, carBAMazepine: increased
Suppository
hepatotoxicity
Alternate name: Tylenol - Nitric oxide, pilocarpine: increased
methoglobinemia, avoid concurrent use
Dose: 1 suppository
- Warfarin: hypoprothrombinemia; long-term use,
Frequency: Q4h PRN high doses of acetaminophen
- Barbiturates, hydantoins: decreased effect;
Class: Nonopioid Analgesics (pain relievers) and increased hepatotoxicity, monitor for
anti-pyrectics (fever reducers) hepatotoxicity
Action: inhibit the synthesis of prostaglandins - NSAIDs, salicylates: increased renal adverse
which are mediators in the CNS for fever & pain reactions

Use: treat mild to moderate pain and fever.


Nursing Intervention:
- Pain/fever: Assess for location, duration, type,
Common Side Effects: aggravating/alleviating factors, intensity;
- Stomach pain, nausea, vomiting assess for diaphoresis, fever; baseline and
Serious Effect: periodically
- Skin rashes & severe skin condition - Monitor liver function studies: AST, ALT,
- Bloody or black, tarry stools bilirubin, creatinine before therapy if long-term
- Liver damage (jaundice, dark urine, extreme
therapy is anticipated; may cause hepatic
tiredness, delirium)
toxicity at doses >4 g/day with chronic use
- Coma & Death
- Monitor renal function studies: BUN, urine
- Swelling, pain or tenderness in abdomen
creatinine, occult blood; albumin indicates
- Hepatoxicity
- Hepatic seizure (overdose) nephritis, check I&O ratio; decreasing output
- Renal failure may indicate renal failure (long-term therapy)
- Monitor blood studies: CBC, PT if patient is
on long-term therapy
Administration: - Assess for chronic poisoning: rapid, weak
- Ask pt to lie left side w/ right knee bent pulse; dyspnea; cold, clammy extremities;
- Lubricate and insert suppository into rectum report immediately to prescriber
(1-3 inches)
- Remain lying down a few minutes
Patient Education:
Dosage Safety:
- Inform patient that toxicity may occur when
- 325-650 mg Q4-6 hrs. as needed
- Max 4,000 mg per day used with other combination products
- Child: depend on body weight (10-15 mg per - Advise patient not to use with alcohol, OTC
kilo Q4-6 hrs) products, or herbals without prescriber
Times: approval
- Onset: 30 mins- 1 hr. - Teach patient to recognize signs of chronic
- Peak: 1-3 hrs. overdose: bleeding, bruising, malaise, fever,
- Duration: 3-4 hrs. sore throat
Contraindication/Caution: - Inform patient that urine may become dark
- Hypersensitivity to APAP, aspartame, brown as a result of phenacetin (metabolite of
saccharin, tartrazine, phenacetin acetaminophen)
- Caution for pt who is pregnant, - Tell patient to notify prescriber for pain or
breastfeeding, geriatric, with anemia, renal/ fever lasting more than 3 days, not to be used
hepatic disease, and chronic alcoholism in <2 yr unless approved by prescriber
Phenobarbital 20 mg per 5 ml Oral Nursing Consideration:
Solution - Assess mental status: mood, sensorium,
affect, memory (long, short), especially
Alternate name: Luminal, Solfoton
geriatric; if using as a hypnotic, assess sleep
Dose: 5 mL patterns during therapy; product suppresses
Frequency: Q8H REM sleep with dreaming
Class: barbiturates - Withdrawal insomnia may occur after short-
Action: Depresses sensory cortex, decreases term use; do not start using product again;
motor activity and alters cerebellar function. insomnia improves in 1-3 nights; may
Raises seizure threshold and inhibits experience increased dreaming
transmission in the NS. - Assess respiratory dysfunction: respiratory
Use: control seizures, relieve anxiety, prevent depression, character, rate, rhythm when
withdrawal symptoms using IV; hold product if respirations are
<10/min or if pupils are dilated; also check VS
Common Effects: q30min after parenteral route for 2 hr
- Drowsiness, dizziness, upset stomach, - Assess for barbiturate toxicity: hypotension;
constipation, feeling hungover pulmonary constriction; cold, clammy skin;
cyanosis of lips; CNS depression; nausea;
Serious Effect:
vomiting; hallucinations; delirium; weakness;
- Serotonin syndrome, headache, dizziness,
coma; pupillary constriction; mild symptoms
drowsiness, fatigue, occur in 8-12 hr without product
- weakness, torsades de pointes, Steven - Assess for pain in post-op patients; pain
Johnson syndrome, toxic epidermal threshold is lowered in patients taking this
necrolysis medication
- Coma - Assess for blood dyscrasias: fever, sore throat,
- Angioedema bruising, rash, jaundice, epistaxis (long-term
- anemia treatment only)
- Assess seizure activity, including type,
Dosage Safety: location, duration, character; provide seizure
- Seizures: 1-3mg/kg per day (adults) precaution
- Sleep prob: 100-200 mg at bedtime
Contraindication/Precautions:
- Pregnancy, breastfeeding, geriatric, Patient Education:
hypersensitivity to barbiturates, porphyria, - Teach patient that hangover is common
hepatic/respiratory disease, nephritis, - Inform patient that physical dependency may
hyperthyroidism, diabetes mellitus result when used for extended time
- Anemia, renal disease - Teach patient to avoid driving and other
activities requiring alertness
- Caution patient to avoid alcohol ingestion
Medication Interactions: and CNS depressants; serious CNS
- Alcohol: ↑ CNS depression depression may result
- Chloramphenicol, disulfiram: ↑ effects - Instruct patient not to discontinue medication
- Doxycycline, metroNIDAZOLE, quiNIDine, quickly after long-term use; may cause
theophylline: ↓ effectiveness seizures; product should be tapered over 1
- Furosemide: ↑ orthostatic hypotension wk;
- Emphasize the need to tell all prescribers
- Valproic acid: ↑ sedation
that a barbiturate is being taken
- Anticoagulants, glucocorticoids, estrogens, - Teach the patient to make position changes
hormonal contraceptives: ↓ effectiveness slowly; orthostatic hypotension may occur
- CNS depressants: ↑ effects - Instruct patient to notify prescriber
- MAOIs, skeletal muscle relaxants immediately if bruising, bleeding occur,
(nondepolarizing), sulfonamides: ↑ effects which may indicate blood dyscrasias
Glucophage 500mg Oral tablet Contraindication/precaution:

Alternate name: Metformin - Contraindication:


Hypersensitivity, Metabolic acidosis
Dose: 1 tab including diabetic ketoacidosis w/ or w/o
Frequency: BID coma, impaired kidney function
- Caution:
Class: Biguanides Pregnancy, Impaired renal and hepatic
function, heart failure
Action:
- Reduce the amount of glucose the liver
produces
- Lessen absorption of glucose in intestine Medication Interactions:
- Raise tissue sensitivity to insulin - Digoxin: ↑ metformin level and digoxin
level
Use - Beta-blocker: ↑ hyperglycemia
- Dofetilide: ↑lactic acidosis, don’t use
- To control blood glucose level of pt w/ type 2 together
diabetes mellitus - Morphine, vancomycin, cimetidine: ↑
metformin level
Nursing Consideration:
- Check pt’ blood glucose
Common: - Monitor S/S of hypoglycemia or
- Diarrhea, Gas, Indigestion hyperglycemia (confusion, lethargy,
- Nausea or vomiting shallow rapid breathing, tachycardia,
- Stomach pain hypotension, nausea & vomiting)
- Headache - Monitor: Liver function (AST, LDH), renal
- Anorexia, change in taste (BUN, creatinine), Blood glucose, A1C,
- Low vitamin B12 level liver enzymes, and vit B12 levels.
Serious Evaluation:
- Lactic acidosis (buildup of lactic acid) Lower glucose level, normal lab result for
- Hyperventilation blood glucose and A1C levels

Dosage Safety: Client Education:


- Tab: max 2550 mg/day (can be crushed) - Advise pt monitor blood sugar
- Ext Rel Tabs: max 2000mg/day (DO NOT - Inform pt to take medication as directed
CRUSH/CHEW) and do not stop abruptly
- Oral sol 500mg/ml - Teach about S/S of lactic acidosis
Times: (hyperventilation, fatigue, chills, severe
- Onset: Unknown abdominal pain, confusion & vomiting)
- Peak: - Inform pt to avoid alcohol
o Immediate rel: 1-2 hr. - Instruct pt to do not intake medication
o Ext Rel: 7 hrs. (over the counter) w/o consulting HCP
o Sol: 2.5 hr. - Discuss to pt about their diet and
- Duration: unknown encourage them to stick to it as much as
possible
Administration: immediate (take w/ meals); ext
rel (take w/ evening meals)
120 ACTUAT Albuterol 0.1mg/ Dosage Safety:
Ipratropium Bromide 0.02/ MDI - Dose: 2 puff every 4-6 hrs. Do not exceed
12 puffs in 24 hrs
Alternate name: Ipratropium Bromide Inhaler Contraindication/Precaution:
- Hypersensitivity to sympathomimetics
Dose: 4 puff
- Precautions: Pregnancy, breastfeeding,
Frequency: Once a day exercise-induced bronchospasm (aerosol) in
children <12 yr, cardiac/renal disease,
Class: Bronchodilator hyperthyroidism, diabetes mellitus,
Action: relaxes smooth muscle; produces hypertension, seizures, hypoglycemia, severe
bronchodilatation; CNS, cardiac stimulation, cardiac disease
increased diuresis, and increased gastric acid
secretion; longer acting than isoproterenol
Medication Interaction:
Use - Digoxin: ↑digoxin level
- Adrenergics: ↑ action of albuterol; do not use
- To open up the airways and treat breathing together
problems like wheezing or shortness of breath - β-Adrenergic blockers: block therapeutic effect
- Treat asthma, bronchitis, emphysema, or other - Bronchodilators (aerosol): ↑ action of
lung disease bronchodilator
- CNS stimulants: ↑CNS stimulation
- Diuretics (potassium-losing): ↑ECG
Common Side effects: changes/hypokalemia
- Shakiness - MAOIs, tricyclics: increased chance of
- Dizziness, headache, nausea hypertensive crisis; do not use together
- Sudden change in mood& increase or decrease Nursing Consideration:
- Oxytocics: severe hypotension; do not use
in appetite - Assess
togetherrespiratory function: pulse oximetry,
- Muscle cramps
- ABGs, lung sounds;
Theophylline: toxicityheart rate, rhythm; B/P,
- Pale skin
- sputum (baseline and during therapy)
Serious side effect - Assess for paradoxial bronchospasm, trouble
- Fast, pounding, or irregular heartbeat breathing with wheezing, notify health care
- Chest pain professional immediately
- Fever, rash, itching, swelling of face - Monitor for S/S of heart problem and serious
- Difficulty breathing or swallowing
side effect like worsening after using the
- Overdose: chest pain, ↓ K level cause muscle
inhaler.
weakness or cramps
Client education:
- Tell patient not to use OTC medications before
Administration: consulting prescribe
- Shake the inhaler than exhale full, place in - Teach patient to use inhaler
mouth and take a deep breath while pressing - Teach patient that if paradoxic bronchospasm
down to release puff occurs to stop product immediately and notify
- Hold breath 5-10 secs then exhale pursed lip prescriber
- Wait 1 min. between puff and rinse mouth after - Instruct patient on administration of dose, not
Times: (INH) to use more than prescribed; serious side
- Onset: 5-15 mins effects may occur; notify HCP immediately if
- Peak: 1 ½- 2 hrs. product does not relieve symptoms
- Duration: 4-6 hrs.
Carbamide peroxide 6.5% Otic Solution Contraindication/Precautions:
- Do not use if you have hole in your eardrum
Alternate name: Debrox
(ruptured eardrum)
Frequency: BID, do not exceed more than QID - Do not use if there’s any sign of ear infection
(pain, swelling, drainage, bleeding)
Class: Astringents
- Pregnancy and lactation
Action: helps soften by releasing hydrogen
Medication Interaction:
peroxide and oxygen in air.
- No significant medication but always inform
Use: helps soften, loosen, and remove built-up
the Healthcare provider about all medication
earwax
you use.
Dosage Safety:
Common Side Effects: 5- 10 drops of the solution instilled into the
- Foaming or crackling sound in the ear affected ear(s) 2 times daily for up to 4 days.
- Temporary decrease in hearing Nurse Consideration:
- Mild feeling of fullness
- Mild itching inside the ear - Assess for ear pain
- Asses for S/S of irritation, allergic reaction.
Serious Side Effects:
Times:
- Severe dizziness
- Worsening ear pain - Onset: immediately
- Trouble breathing - Peaks: softening
- Allergic reactions (skin, rash, itching, hives, - Durations: 4 days
swelling of face, lips, tongue, throat)

Preparation:
- Warm the eardrops prior to use
Administration: Patient Education:
- Lie down or tilt your head with your ear - Do not use for longer than 4 days without
facing upward. Open the ear canal by gently consulting your doctor
pulling your ear back or pulling downward on - If your ear becomes painful, irritated, or if
the earlobe when giving this medicine to a there’s no improvement after few days, stop
child. using the drops and contact HCP.
- You may hear a bubbling sound inside your
- Store the bottle at room temperature.
ear. This is caused by the foaming action of
- Avoid using cotton swabs as they can push
carbamide peroxide, which helps break up
the wax inside your ear. wax further in.
- Stay lying down or with your head tilted for - Teach proper medicine administration
at least 5 minutes. You may use a small
piece of cotton to plug the ear and keep the
medicine from draining out.
- Do not touch the dropper tip or place it
directly in your ear. Wipe the tip with a clean
tissue but do not wash with water or soap.

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