Product Name: Bisoprolol fumarate
Revision Date: 8/30/2018
Safety Data Sheet(SDS)
I. PRODUCT AND COMPANY IDENTIFICATION
Product Name: Bisoprolol fumarate
Product Catalog Number: B1354
CAS Number: 104344-23-2
Company: APExBIO Technology
7505 Fannin street, Suite 410,
Houston, TX 77054, USA
+1-832-696-8203 TEL
+1-832-641-3177 FAX
+1-855-577-7998 EMERGENCY PHONE
II. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards: Acute toxicity,oral(Category 4),H302
III. COMPOSITION/DATA ON COMPONENTS
Formula: C22H35NO8
Molecular Weight : 441.52
IV. FIRST AID MEASURES
After Inhalation: If inhaled, remove to fresh air; if breathing is
difficult, give oxygen; if breathing stops, give
artificial respiration.
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After skin contact: Flush with copious amounts of water; remove
contaminated clothing and shoes; call a physician;
Take victim to hospital immediately; call a
physician.
After eye contact: Check for and remove contact lenses and flush
with copious amounts of water; assure adequate
flushing by separating the eyelids with fingers;
call a physician.
After swallowing: If swallowed, wash out mouth with copious
amounts of water; call a physician
V. FIRE FIGHTING MEASURES
Conditions of flammability: Not flammable or combustible.
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry
chemical or carbon dioxide.
Special protective equipment for Wear self contained breathing apparatus for fire
firefighters: fighting if necessary.
Hazardous combustion products: Hazardous decomposition products formed under
fire conditions. - Carbon oxides, nitrogen oxides
(NOx), Sulphur oxides.
VI. ACCIDENTAL RELEASE MEASURES
Personal precautions: Wear respiratory protection. Avoid dust
formation. Avoid breathing vapors, mist or gas.
Environmental precautions: Do not let product enter drains. Prevent further
leakage or spillage if safe to do so.
Methods and materials for Pick up and arrange disposal without creating
containment and cleaning up: dust. Sweep up and shovel. Keep in suitable,
closed containers for disposal.
VII. HANDLING AND STORAGE
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Precautions for safe handling: Avoid contact with skin and eyes. Avoid formation
of dust and aerosols.
Provide appropriate exhaust ventilation at places
where dust is formed.
Conditions for safe storage: Keep container tightly closed in a dry and
well-ventilated place.
Recommended storage temperature: Store at
-20°C
Keep in a dry place.
VIII. EXPOSURE CONTROLS AND PERSONAL PROTECTION
Personal protective equipment as Contains no substances with occupational
follows: exposure limit values.
Respiratory protection: Where risk assessment shows air-purifying
respirators are appropriate use a full-face particle
respirator type N99 (US) or type P2 (EN 143)
respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of
protection, use a full-face supplied air respirator.
Use respirators and components tested and
approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Hand protection: Handle with gloves. Gloves must be inspected
prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid
skin contact with this product. Dispose of
contaminated gloves after use in accordance with
applicable laws and good laboratory practices.
Wash and dry hands.
Eye protection: Use equipment for eye protection tested and
approved under appropriate government
standards such as NIOSH (US) or EN 166(EU).
Skin and body protection: Choose body protection in relation to its type, to
the concentration and amount of dangerous
substances, and to the specific work-place. The
type of protective equipment must be selected
according to the concentration and amount of
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the dangerous substance at the specific
workplace.
Hygiene measures: General industrial hygiene practice.
IX. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) Appearance No data available
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing point No data available
f) Initial boiling point and No data available
boiling range
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or No data available
explosive limits
k) Vapour pressure No data available
l) Vapour density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient No data available
p) Auto-ignition temperature No data available
q) Decomposition temperature No data available
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r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
Other safety information
No data available
X. STABILITY AND REACTIVITY
Chemical stability: Stable under recommended storage conditions.
Possibility of hazardous reactions: No data available.
Conditions to avoid: No data available.
Materials to avoid: Strong acids, Strong bases.
XI. TOXICOLOGICAL INFORMATION
Carcinogenicity
IARC: No component of this product present at levels
greater than or equal to 0.1% is identified as
probable, possible or confirmed human
carcinogen by IARC.
ACGIH: No component of this product present at levels
greater than or equal to 0.1% is identified as a
carcinogen or potential carcinogen by ACGIH.
NTP: No component of this product present at levels
greater than or equal to 0.1% is identified as a
known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels
greater than or equal to 0.1% is identified as a
carcinogen or potential carcinogen by OSHA.
XII. ECOLOGICAL INFORMATION
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General notes: No data available.
XIII. DISPOSAL CONSIDERATION
General notes: Dispose of in accordance with prevailing
country, federal, state and local regulations
XIV. TRANSPORT INFORMATION
DOT (US): This substance is considered to be non-hazardous
for transport.
IMDG: UN number: 3077
Class: 9
Packing group: III
EMS-No: F-A, S-F
Proper shipping name: Environmentally
hazardous substance, solid, n.o.s.
Marine pollutant: Marine pollutant
IATA: UN number: 3077
Class: 9
Packing group: III
Proper shipping name: Environmentally
hazardous substance, solid, n.o.s.
XV. REGULATIONS
SARA 302 Components: SARA 302: No chemicals in this material are
subject to the reporting requirements of SARA
Title III, Section 302.
SARA 313 Components: SARA 313: This material does not contain any
chemical components with known CAS numbers
that exceed the threshold (De Minimis) reporting
levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: Acute Health Hazard.
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Massachusetts Right To Know No components are subject to the Massachusetts
Components: Right to Know Act.
Pennsylvania Right To Know No components are subject to the New Jersey
Components: Right to Know Act.
New Jersey Right To Know No components are subject to the New Jersey
Components: Right to Know Act.
California Prop. 65 Components: This product does not contain any chemicals
known to State of California to cause cancer, birth
defects, or any other reproductive harm.
XVI. OTHER INFORMATION
Copyright 2018 APExBIO License granted to make unlimited paper copies for internal
use only. The above information is believed to be correct but does not purport to be all
inclusive and shall be used only as a guide. The information in this document is based
on the present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties
of the product. APExBIO Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See www.
[Link] and/or the reverse side of invoice or packing slip for additional terms and
conditions of sale.
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