Pharmaceutical Engineering: Fluid Flow Basics
Pharmaceutical Engineering: Fluid Flow Basics
Pharmaceutical Engineering The d1stinction between solids and fluids is made by evaluating the VISCOSIty of the
For example:
substance
If you are pour1ng water from a mug, the velocity of water is very lhigh over the lip. moderately
high approaching the lip, and very low at the bottom of the mug
The unbalanced force is gravity, and the flow contmues as long as the water is avarlable and the
mug is tiited
Fuid pressure
The pressure which is applies by the fluid.
UNIT-I Also known as hydrostatic pressure
Reynolds number and its
" Flow of fluids: Types of manometers, Pressure:
significance, Bernoulli's theorem and its applications, Energy losses, Force f Mg
Orifice meter, Venturimeter, Pitot tube and Rotometer. Pressure
Area A
Size Reduction: Objectives, Mechanisms & Laws governing size
reduction, factors affecting size reduction, principles, construction,
energy
Force
Mg
working, uses, merits and demerits of Hammer mill, ball mill, fluid A A
mill, Edge runner mill & end runner mill.
Size Separation: Objectives, applications & mechanism of size P= phg
separation, official standards of powders, sieves, size separation Principles, Application of Flow of Fluids:
construction, working, uses, merits and demerits of Sieve shaker, cyclone To transfer air and nutrient broth into the fermenter,
separator, Airseparator, Bag filter & elutriation tank. For passing of reactant (liquid or gases) into the reaction apparatus,
During packaging and bottling of medicament (mainly liquid and semisolid dosage form).
For mixing of solids and liquids to form a suspension, and
To transfer sterile air and water while preparing parenteral.
Manometer:
It is a devices which is used to measure pressure difference.
For Notes Regular Visit our Website: wuw.nOleskar1s O! For Notes Regular Visit our Website:
Noteskarts
Unit-1 Noteskarts
Subscribe & Visit our Website
Subscribe & Visit our Webs1le For Notes Fo Noles
Type of Manometer:
Unit.4
1. Simple manometer
2. D1flerent1al Manometer
1. S1mple manometer
These are those manometers which measure the pressure at
any pont is a tube etc
" S1mple Manometers: These manometers are made up of glass tubes. One end of these remains
open to the atmosphere and the other end are connected to a point where pressure is to be ñ-Tube Differential Manometer
mcasurcl
at the Same ye!
U-Tube Differential Manometer
Ex U-tube manoneter at the Differeat Levet
e'eete riutekarts rom
U-tube manometer:
A U-ube manometer is a simple device used to measure pressure It cons1sts of a U-shapcd The fwo ends are linked to the twO
plass tuhe filled with a lhquid, typically mercury. spots in the
Allow pressure at point A to he yreater than pipe where a pressure differential is necessarv
One leg of the tube Is connected to the stem whose pressure is to be measued, while the The higher pressure at A will hen cau[e the pressure at point B
other leg IS upen to the atmosphere When there is no pressure difference between the two to this effect, the heavy liquid in the heavier liquid in the U-tube to travel downward Due
legs. the hquid levels in the two legs will be equal. nght limb will ascend, causing the heavy liquid in the left
limb to descend
Re pVD
h =heght o hea qund above reference linc
Where:
p is the density of the fluid
2. Differential Manometer Vis the velocity of the fluid
A differential manometer is a device that measures the difference in pressure between two places. D is the characteristic length of the flow (e.g.. the diameter ofa
pipe)
They can range from s1mple to complex digital equipment. u is the viscosity of the fluid
Standard manometers are used to measure the pressure in a container by comparing it to normal
atmospheric pressure.
Differential manometers are also used to compare the pressure of two different containers It gives that flowv is steady or tubulent
Example: U-tube d1fferential manometer It Re <1000 then flow is steady.
It Re>2000 aprox then it is turbulent.
U-tube differential manometer:
As shown in the pIcture, the point of measurement is attached to one end of a glass tube Significance:
into a V while the other end is exposed to the atmosphere. curved
The Reynolds number is that it can be used to predict the type of flow that will occur in a given
situation.
This information can be used to design and optimize fluid systems to ensure that they operate
efficiently and safely.
It also used to study the sedimentation rate
for
V-AHeV,)
phosper
the
Piate
measurement 2,
bronze.
nickel
of
flow
and
throughmonel.
a An
pipe.
orifice
meter
Unit-1