INORGANICPHARMACEUTICALCHEMISTRY

1. Whatelementisalsoknownasdephlogistic Whatconditionresultsfromthedeficiencyofiodine?
atedair?
A. Hepatitis
A. Nitrogen B. Goiter
B. Oxygen C. Infection
C. Hydrogen D. Scurvy
D. Sulfur E. Peripheralneuropathy
E. Helium
7. Whatarethemetalsthatcombinetoformthealloy,ferrochro
2. Whatisthepredominantionintheextracellularfl me?
uid?
A. Leadandiron
A. Na+1 B. Leadandchromium
B. K+1 C. Chromiumandtin
C. Mg+2 D. Ironandtin
D. Ca+2 E. Ironandchromium
E. Mn+2
8. WhichofthefollowingstatementsaboutBordeauxMix
3. Whatisthehalogenusedaswaterpurifier? tureis/aretrue?
A. F I. Itisusedasanantiseptic
B. Cl II. Itisusedasanalgicide-fungicide
C. Br III. Itcontainscopper
D. I IV. Itcontainscobalt
E. At
A. IandII
4. Which of the following substances B. IIandIV
isemployedinthetreatmentofmentaldisorder? C. IIandIII
A. MgSO4 D. IIIandIV
B. K2Cr2O7 E. I,II,III
C. Li2CO3 9. Inertgasesbeinginvestigatedforpossibleuseasinhalatory
D. NaHCO3 anesthetic
E. KNO3
I. Kr
5. Whatisthemostreactiveelementamongthehalogens? II. Xe
A. F III. Ar
B. Cl IV. He
C. Br
D. I A. IandII
E. At B. I,II,andIII
C. IIandIV
6.
D. IandIV
INORGANICPHARMACEUTICALCHEMISTRY
10. Whatisthecompositionofartificialair? Whatisthemostabundantmetalontheearth'strust?
A. 40%O2and60%He A. Fe
B. 20%O2and80%He B. Al
C. 20%Heand80%O2 C. Cu
D. 80%Krand20%He D. Au
E. 40%Krand60% E. Si

11. ThefollowingtermsareusesofRochellesaltEXCEPT: 16. Whatelementscomposethealloybronze?

A. CuandAu
A. Cathartic
B. CuandZn
B. Diuretic
C. CuandSn
C. Sequesteringagent
D. CuandTn
D. Preservative
E. CuandAg
E. Noneoftheabove
17. Themeasureoftheacidityofasolutionisalsoknownas
12. What metal is unaffected by body
fluidshenceitisusedinsuchrepairofbones,nervesandmuscles? A. pH
B. pOH
A. Aluminum C. Buffer
B. Tantalum D. Concentration
C. Tin E. pI
D. Thorium
E. Silicon 18. What inert substance is used to prolong theshelf-
lifeofproductsbydisplacingairinsidethecontainer?
13. Whatistheofficialbariumsaltusedinmedicine as a A. Oxygen
radiopaque substance
B. Helium
inroentgenographicexaminationoftheGIT
C. Carbondioxide
D. Nitrogen
A. BaCl2
E. [Link]
B. BaSO4
C. Ba(NO3)2 19. WhichamongtheelementsdoesNOTformbasicanhydride?
D. Ba3(PO4)2
E. BaCO3 A. Ca
B. Na
C. Ba
14. What is the synthetic, radioactive noble D. Mg
gasusedinthetreatmentofcervicalandorallesion E. S

A. Ar
B. Ir
C. Xe
D. Rn
E. Noneoftheabove
15.
INORGANICPHARMACEUTICALCHEMISTRY
20. Which of the following substance WhatisthecolorofthecylinderthatisusedtocontainO2?
is/areusedasinhalantinallpathologicalconditionscharacteriz
edbydyspnea? A. Black
B. Green
I. Oxygen C. Gray
II. Helium D. Brown
III. Carbondioxide E. Yellow
IV. Nitrogen
A. Ionly 26. Glauber'ssaltischemicallyknownas
B. IIonly A. MgSO4
C. IandII B. K2SO4
D. IIandIII C. FeSO4
E. IandIV D. Na2SO4
21. An extremely unreactive E. H2SO4
substanceconsideredtohavethelowestcoefficientofthe 27. Magnesiaischemicallyknownas
rmalexpansionamongmetals
A. MgCO3
A. Gold B. MgO
B. Platinum C. Mg(OH)2
C. Palladium D. MgCl2
D. Silicon E. MgSO4
E. Krypton
28. Calcinedmagnesiteischemicallyknownas
22. Whatisthemeaningof“halogen”?
A. MgCl2
A. Acid-former B. MgSO4
B. Water-former C. MgCl2
C. Niter-producer D. MgCl2
D. Seasalt-former E. MgCO3
E. Noneoftheabove
29. Boneashischemicallyknown
23. Whichofthetwofollowingsubstancesisnativehydrous
magnesiumsilicate? A. Ca(OH)2
B. Ca5(OH)(PO4)3
A. Talc C. CaO
B. Pumice D. Ca(OCl)2
C. Kaolin E. CaSO4
D. Bentonite
E. Clay 30. Whatistheantidoteforzincpoisoning?

24. WhatistheactiveingredientofWhitelotion? A. Magnesiumsulfate

B. Magnesiumhydroxide
A. CdS C. Sodiumbicarbonate
B. SeS D. Sodiumcarbonate
C. PbS E. Sodiumchloride
D. ZnS
E. MnS
25.
INORGANICPHARMACEUTICALCHEMISTRY
31. WhatThechemicalformulaofcinnabar? Whatisthecolorimpartedtotheflamebylithium?

A. HgS A. Yellow
B. Hg2Cl2 B. Brickred
C. ZnO C. Green
D. HgCl2 D. Violet
E. CdS E. Crimson

32. Lungetestinsensitivitytestforwhation? 37. Whatistheuseofbentonite?

A. Phosphate A. Suspendingagent
B. Nitrate B. Lubricant
C. Sulphate C. Binder
D. Carbonate D. Precipitant
E. Silver E. Bulkingagent

33. WhichofthefollowingphrasesdescribesCATIONS? 38. Whichamongthefollowinggasesisusedasanantioxidant?

A. Examplesarehalidesandcyanides A. Helium
B. Negativelychargedparticles B. Carbondioxide
C. Atomsthatgainedelectrons C. Nitrogen
D. Hasmoreprotonsthanelectrons D. Hydrogen
E. Noneofthese E. Noneoftheabove

34. Whatistheuseofcreamoftartar? 39. Oxidesofnonmetallicelementsaredescribedto

be
A. Buffer
A. Alkaline
B. Diuretic
B. Acidic
C. Bulkingagent
C. Amphoteric
D. Adsorbent
D. Neutral
E. Urinaryacid
E. Noneoftheabove
35. Whatelementisusedintheprophylaxisofdentalcaries? 40. Whichamongthefollowingsubstanceisconsideredasv
olatilebase?
A. Chlorine
B. lodine A. KOH
C. Calcium B. NaOH
D. Fluorine C. Ca(OH)2
E. Strontium D. NH4OH
36. E. Al(OH)3
INORGANICPHARMACEUTICALCHEMISTRY
41. WhathappenstotheoxidizingagentinaREDOXreaction? Thefollowingitemsdescribetheuseofsodiumiodide,EXC
EPT
A. Isoxidized
B. Losselectron I. Expectorant
C. Isreduced II. Antikeratogenic
D. Valenceincreased III. Solubilizer
E. Notaffected IV. Antifungal
42. Whatisthemostelectronegativeelementintheperiodictabl A. Ionly
e? B. IIandIII
C. IIonly
A. I
D. IIIandIV
B. Cl
E. IandIII
C. Fe
D. C 47. Whichamongthefollowingsubstancesisusedashypote
E. Noneoftheabove nsiveagent?
43. Allthefollowingsubstancesarewiththerapeuticp A. K2SCN
roperty,EXCEPT: B. MgSO4
C. Na3PO4
A. Carbondioxide
D. CaCl2
B. Helium
E. CaCO3
C. Oxygen
D. Hydrogen 48. Whatistheofficialantidoteforphosphoruspoisoning?
E. Noneoftheabove
A. Whitevitriol
44. Parisgreenischemicallyknownas B. Greenvitriol
A. Cupricoxide C. Oilofvitriol
B. Calciumsulfate D. Bluevitriol
C. Copperacetoarsenite E. Rochellesalt
D. Cupricchloride 49. Whatelementisglucinum?
E. Ammoniumchloride
A. Lithium
45. WhatistheuseofLassar'spaste? B. Strontium
A. Keratolytic C. Manganese
B. Antiseptic D. Beryllium
C. Demulcent E. Sulfur
D. Counterirritant 50. Whatisnativemagnesiumsulfate?
E. Analgesic
46. A. Kieserite
B. Dolomite
C. Magnesite
D. Talc
E. Asbestos
INORGANICPHARMACEUTICALCHEMISTRY
51. Whatcompoundofsulfurisconsideredtheyellowsulfide? Amongthehalogenswhichelementisthemostmetallic?

A. MnS A. Chlorine
B. ZnS B. Bromine
C. Sb2S3 C. Fluorine
D. CdS D. Iodine
E. PbS E. Astatine
52. What substance may be used to clean 57. Artificialradioactiveisotopesemitthefollowingpa
aglassapparatuswhichisparticularlygreasy? rticles,EXCEPT

A. Nitricacid A. Alphaparticles
B. Concentratehydrochloricacid B. Betaparticles
C. Chromosulfuricacid C. Deltaparticles
D. Hypochlorousacid D. Gammaray
E. Sulfuricacid E. Noneoftheabove
53. What is the color imparted by 58. Saltoftartarischemicallyknownas
calciumchloridetotheflameviewedthroughcobaltglass?
A. Sodiumcarbonate
A. Crimsonred B. Sodiumbicarbonate
B. Lightgreen C. Potassiumcarbonate
C. Intenseyellow D. Potassiumtartrate
D. Nill E. Sodiumlactate
E. Brickred
59. ThereagentthatwillprecipitateoutGroupIcationsis
54. WhatelementwasnamedfromaGreekwordwhichme
an‘acidformer’? A. Hydrogensulfide
B. Dilutehydrochloricacid
A. Hydrogen C. Ammoniumsulfide
B. Nitrogen D. Sodiumbiphosphate
C. Sulfur E. Sodiumhydroxide
D. Oxygen
E. Chlorine 60. A type of water that contains iron in solutionor
suspension and are characterized by
55. Whatisthemoststablediatomicmolecule? aferruginoustasteisknownas

A. Nitrogen A. Salinewater
B. Oxygen B. Lithiawater
C. Bromine C. Alkalinewater
D. Hydrogen D. Chalybeatewater
E. Fluorine E. Mineralwater
56.
INORGANICPHARMACEUTICALCHEMISTRY
61. Whatistheuseofsugarofleadwhenappliedexternal Themoststablecomplexesareformedbytheionsinwhichgrou
ly? pintheperiodictable?

A. Astringent A. GroupIA
B. Antiseptic B. GroupIB
C. Styptic C. GroupVIA
D. Acid-neutralizer D. GroupVIIA
E. Counterirritant E. GroupVIII
62. What color does Sb impart to thenon-
67. Whattypeofligandisethylenediamine?
luminousBunsenflame?

A. Yellowgreen A. Bidentate
B. Crimson B. Pentadentate
C. Blue C. Unidentate
D. Brickred D. Hexadentate
E. Green E. Polydentate

63. Thefollowingitemsdescribetheuseofsulfur,EXCEP 68. Inanalkalinesolvent,thecoloroftheiodinesolutionproducedi

T: susually

A. Catharticaction A. Blueblack
B. Anti-scabies B. Violet
C. Stimulantinalopecia C. Orange
D. Counterirritant D. Red
E. Antiteratogenic E. Colorless

64. Dryiceischemicallyknownas 69. This principle states that, in a stablecomplex, there

may be no high concentration
A. Carbonmonoxide ofnegativeorpositivecharge,andthatchargewilltend to
B. Carbondioxide distribute itself over the atoms within acomplex in such a
C. Nitrogen way that the net charge oneachatomapproacheszero.
D. Hydrogen
E. Hydrogensulfide A. LawofHess
B. Electronegativeprinciples
65. Devarda'salloycontains C. Aufbauprinciple
D. Henry'sLaw
A. Cu,Sn E. Electroneutralityprinciple
B. Pb,Sb,Sn
C. Cu,Ni
D. Cu,Al,Zn
E. Bi,Pb,Sn
66.
INORGANICPHARMACEUTICALCHEMISTRY
70. Whatelementdecreasesthecoefficientofexpansionof TheacidutilizedinXanthoproteictest
glass?
A. Nitricacid
A. Cobalt B. Hydrochloricacid
B. Boron C. Sulfuricacid
C. Platinum D. Aceticacid
D. Potassium E. Boricacid
E. Iron 76. Permanenthardwatermaybesoftenedusingwhichm
71. Epsom'ssaltischemicallyknownas ethods?

A. Sodiumsulfate A. Additionofammonia
B. Sodiummetaphosphate B. Boiling
C. Magnesiumsulfate C. Clark’sLimeprocess
D. Calciumsulfate D. Demineralization
E. Calciumphosphate E. Haber’sprocess

72. Parenteral preparations 77. Whatistheprincipalanionintheintracellularfl

containingbacteriostatic water for injection may uidcompartment?
beadministeredthroughthefollowingrouteEXCEPT
A. Chlorine
A. Subcutaneous B. Sulfate
B. Intramuscular C. Phosphate
C. Intrathecal D. Carbonate
D. Intravenous E. Bicarbonate
E. Noneoftheabove
78. Which iron compound has a
73. Whatelementpredominatesintheplasmaandinterstitialfl superiorresistancetooxidationuponexposuretoair?
uid?
A. Ferrousoxide
A. Potassium B. Ferrousfumarate
B. Calcium C. Ferrousgluconate
C. Sodium D. Ferroussulfate
D. Magnesium E. Ferrouslactate
E. Oxygen
79. Whatmineralisdeficientinparakeratosis?
74. WhatmetalisidentifiedinMarshtest?
A. Zinc
A. Siver B. Copper
B. Arsenic C. Magnesium
C. Lead D. Iodine
D. Cadmium E. Chromium
E. Mercury
75.
INORGANICPHARMACEUTICALCHEMISTRY
80. Whatmaterialisproduceduponthefusionof pure silica Whichofthefollowingcompoundsareefflorescentsubst
with a base such as sodiumcarbonate? ances

A. Pumice I. Glauber'ssalt
B. Quartz II. Bluevitriol
C. Glass III. Epsomsalt
D. Talc
E. Kaolin A. IandII
B. IandIII
81. Onehundredvolumesofhydrogenperoxideequalto C. IIandIII
D. I,II,III
A. 3%
E. Noneoftheabove
B. 6%
C.10% 86. Compoundcapableofinterferingthepassageofx
D.30% -raysareemployedas
E.100%
A. Lavage
82. Ironoxidesareusuallyemployedas B. Chemotherapeuticagent
A. Topicalprotective C. Radiopaque
B. Astringent D. Radioisotope
C. Hematinic E. Enema
D. Laxative 87. Used as bone replacement for
E. Pigment temporarybracesoflongbonesandtocloseopeningsintheskull
83. Aromatic Ammonia Spirit, USP must bestoredin A. Silver
A. Amberbottles B. Tantalum
B. Clearglasscontainers C. Platinum
C. Greenbottles D. Zinc-eugenolcement
D. Rubbercontainers E. Calciumsulfate
E. Borosilicatesglasscontainers 88. Gold has been used in the treatment of
84. Whatistheonlyrouteapprovedfortheadministration thefollowingconditions
ofDextranInjection? I. Tuberculosis
A. Intraperitonial II. Lupuserythematosus
B. Intradermal III. Rheumatoidarthritis
C. Intramuscular
D. Subcutaneous A. IandII
E. Noneoftheabove B. IandIII
C. IIandIII
85. D. I,II,andIII
E. Noneoftheabove
INORGANICPHARMACEUTICALCHEMISTRY
89. A solution produced from the reaction What substance is formed when
ofmercuriciodidewithpotassiumiodideisknownas ozonedissolvesinandbondswithsubstancessuchassuchturpenti
neoil,cinnamonoilandoliveoil?
A. Nessler’sreagent
B. Valser'sreagent A. Peroxides
C. Fehling'sreagent B. Ozonizer
D. Benedict'sreagent C. Dehydrogenatedoils
E. Mayer'sreagent D. Ozonides
E. Oxidizedoils
90. Nativehydratedaluminumsilicateisalsoknownas
95. WhichamongthefollowingisNOTauseofsodiumhypochlori
A. Kaolin tesolution?
B. Talc
C. Pumice A. Bleachingagent
D. Siloxane B. Oxidizingagent
E. Bentonite C. Disinfectant
D. Preservative
91. Burrow'ssolutioncontains E. Noneofthese
A. Alum 96. Corrosivesublimateischemicallyknownas
B. Leadsubacetate
C. Aluminumacetate A. Mercurybichloride
D. Calciumhydroxide B. Mercurouschloride
E. Silvernitrate C. Ammoniatedmercury
D. Ammoniatedsilvernitrate
92. Thepurestnativeformofuncombinedcarboniskno E. Leadacetate
wnas
97. Rinmann'sgreenischemicallyknownas
A. Graphite
B. Diamond A. Cobaltousoxide
C. Charcoal B. Zincacetate
D. Buckminsterfullerene C. Potassiumferrocyanide
E. Coal D. Copperacetoarsenite
E. Cobaltzincate
93. What is formed when aluminum
silicatescombinewithimpuritiesofcalcium,magnesiumironoxid 98. Intestingforthepresenceofsugarinurine,what color is
es,andfragmentsofquartz? produced upon the addition ofFehling'ssolution?

A. Clay A. Brickredprecipitate
B. Kaolin B. Bluishgreencoloration
C. Pumice C. Yellowprecipitate
D. Bentonite D. Whiteprecipitate
E. Attapulgite E. Violetringatthejunction
94.
INORGANICPHARMACEUTICALCHEMISTRY
99. Whatistheoxidationstateofoxygenintheperoxideion? Whichreagentmaybeusedtodifferentmercuroussaltsfrom
mercuricsalts?
A. -2
B. -1 A. Potassiumhydroxide
C. 0 B. Cupricsulfate
D.+1 C. Hydrogensulfide
E.+2 D. Sodiumhydroxide
E. Leadacetate
100. Whatisthecoloroftheprecipitateformedwhen
mercuric salts are treated with sodiumhydroxideTS? 105. Which metals react violently with water
toproducehydrogengasandmetallichydroxides?
A. Crimson
B. White A. Alkalineearthmetals
C. Violet B. Coinagemetals
D. Yellow C. Alkalimetals
E. Black D. Rareearthmetals
E. Volatilemetals
101. What is the rationale in giving a patientLugol's
solution at least 24 hours before 106. Anentitythatprovidesapairofelectronsinacoordinatec
theadministrationofradioactiveiodine? ovalentbondisknownas

A. Topreventthedepletionofiodine A. Electronprovider
B. Tosaturatethethyroidglandwithiodine B. Donorspecies
C. Topreventtheuptakeoftheradiationsubstance C. Acceptorspecies
D. AandB D. Ligand
E. BandC E. Base
102. WhatdoesVogelreactiontestsfor? 107. Sympatheticinkischemicallyknownas
A. Ferrousions A. Cobaltouschloride
B. Ammoniumions B. Silvernitrate
C. Cobaltousions C. Sodiumthiosulfate
D. Nickelions D. Cadmiumchloride
E. Antimonyions E. Leadsubacetate
103. Benedict’ssolutioncontainsallofthefollowingcom 108. Whiteprecipitateischemicallyknownas
poundEXCEPT
A. Zincsulfide
A. Ferrousoxide B. Ferricoxide
B. Sodiumcarbonate C. Ammoniatedmercury
C. Cupricsulfate D. Mercurouschloride
D. Sodiumcitrate E. Magnesiumsulfate
E. Noneoftheabove
104.
INORGANICPHARMACEUTICALCHEMISTRY
109. What substance is used for its ability toabsorb Membersofthe‘heavyplatinummetals’include
carbon dioxide from expired air inmetabolicfunctiontest?
A. Ruthenium
A. Limewater B. Iridium
B. Sodalime C. Rhodium
C. Slakelime D. Paladium
D. Calx E. Francium
E. Silica
115. Faulty calcium metabolism defined as
110. Whatisthechemicalformulaofsodaash? areducedvolumeofbonetissueperunitvolumeof bone tissue
per unit volume of anatomicalbone and commonly affects
A. NaHCO3 postmenopausalwomenisknownas:
B. KHCO3
C. Na2CO3 A. Osteoporosis
D. Na2CO35H2O B. Rickets
E. Na2CO3H2O C. Paget'sdisease
D. Hypocalcemia
111. Whatconditionsresultsfromhydrogenperoxidesolu E. Hypomagnesemia
tion’scontinueduse?
116. Organicmercurialsaltswerepreviouslyused as
A. Acidosis diuretics and are all administeredparenterally,EXCEPT
B. Hairytongue
C. Esophagitis A. Meralluride
D. Gingivitis B. Sodiummercaptomerin
E. Diplopia C. Calomel
D. Chlormerodrin
112. This is used to provide an E. Ethylmercury
inertatmospheretoretardoxidationincodliveroil,oliveoilandm
ultiplevitaminpreparations 117. This element can replace calcium in boneformation
and has been used to hasten
A. Helium bonedemineralizationindiseasessuchosteoporosis
B. Nitrogen
C. Hydrogen A. Strotium
D. Carbondioxide B. Barium
E. Oxygen C. Beryllium
D. Magnesium
113. Temporary hard water is caused by E. Calcium
thepresenceinsolutionofcalciumormagnesium
. 118. Betadineantiseptictopicalsolutioncontains%o
fiodine
A. Sulfate
B. Chloride A.0.5%-1%
C. Hydroxide B.10%
D. Bicarbonate C.5%
E. Phosphate D.7.5%
114. E.12%
INORGANICPHARMACEUTICALCHEMISTRY
119. This compound has been used in Fool’sgoldischemicallyknownas
[Link],extended
use of this product may result toargyriaandnephritis A. Goldsodiumthiomalate
B. Auricselenite
A. Silvernitrate C. Ironpyrite
B. Silverchloride D. Ferrouscarbonatewithshale
C. Silvertrinitrophenolate E. Nickel
D. Silverprotein
E. Elementalsilver 125. Whatistheexplosiveformofantimony?

120. This sodium salt does not A. Metallicform

producesystemicalkalosisreadyandisantiketogenic B. Amorphousform
C. Crystallineform
A. Sodiumbicarbonate D. Blackantimony
B. Sodiumlactate E. Noneoftheabove
C. Sodiumgluconate
126. WhatisthechemicalformulaofSaltofwormwood?
D. Sodiumcitrate
E. Sodiumacetate A. KHCO3●4H2O
121. Freshsilverstainsonskinmaybebestremovedbypain B. K2CO3●1½H2O
tingtheaffectedwith C. CH3COOK
D. K2HPO4
A. Tinctureofiodine E. CH3COONa
B. Sodiumthiosulfate
127. Elementsexhibitamphotericpropertyinclude:
C. Sodiumpicrate
D. Potassiumcyanide I. Al
E. Sodiumchloride II. Sn
122. Thissubstancegivescalamineitspinkcolor III. Zn
IV. Cu
A. Zinciodine
B. Ferrousoxide A. IandIIonly
C. Zinccarbonate B. IIandIIIonly
D. Ferricoxide C. I,II,andIIIonly
E. Zincsulfide D. IandIVonly
E. I,II,III,andIV
123. Flash-light powders are mixtures
ofpotassiumchlorateorbariumperoxideandthepowderedform 128. In a weakly acidic medium, the reactionbetween this
ofthiselement metal and stannous chloride
willproduceapurpleprecipitatecommonlyknownaPurpleofCassi
A. Sulfur us
B. Aluminum
C. Magnesium A. Tin
D. Phosphorus B. Gold
E. Sodium C. Silver
124. D. Lead
E. Copper
INORGANICPHARMACEUTICALCHEMISTRY
129. Whatisthemostdesirableformoftalcforuseincosmetic This compound is said to be therecommended calcium
pharmaceuticals? salt as
electrolytereplenisherbecauseitprovidesanoptimumratio
A. Amorphous of1:1calciumtophosphate
B. Foliated
C. Fibrous A. Calciumlactate
D. Granular B. Calciumcarbonate
E. Noneoftheabove C. DibasicCalciumphosphate
D. Tribasiccalciumphosphate
130. What commercial iron- E. Ferrousgluconate
containingpreparationhastheadvantageofbeingtheleasti
rritatingtotheGItract? 135. Vieminckx’s solution, a mixture
preparedbyboilinglimeandsublimedsulfur,isusedas
A. Feosol®
B. Hemobion® A. Cathartic
C. ReviconMax® B. Scabicide
D. Cherifer®capsul C. Antifungal
E. Capsebon® D. Irritant
E. Disinfectant
131. Whatisanativeformofcalciumcarbonatethat has been
freed from most of its impuritiesthroughelutriation? 136. Fowler'ssolutionischemicallyknownas

A. Dropchalk A. Dilutedsodiumhypochlorite
B. PrecipitatedChalk B. Copperacetoarsenite
C. Muriateoflime C. Potassiumarsenite
D. Milkoflime D. Bromine,tenth-normal
E. Noneoftheabove E. Calciumsulfate

132. A property of some substance to 137. Nordhausenacidalsorefersto

losewatermoleculesfromacrystallinestructure A. Muriaticacid
A. Dehydration B. Phosphoricacid
B. Hygroscopicproperty C. Concentratednitricacid
C. Deliquescence D. Fumingsulfuricacid
D. Efflorescence E. Dilutedhydrochloric
E. Noneoftheabove 138. Theleastabundantofallinertgases
133. The aluminum magnesium silicate, alsoknown as A. Krypton
floridin, is a low plasticity clay- B. Xenon
[Link] C. Radon
ationofoils D. Argon
E. Noneoftheabove
A. Kaolin
B. Bentonite
C. Fuller'searth
D. Pumice
E. Talc
134.
INORGANICPHARMACEUTICALCHEMISTRY
139. WhatisthedifferencebetweenlodineTinctureandl Whichamongthesehydroxidesarethemostsoluble?
odineSolution?
A. Strontiumhydroxide
A. Theconcentrationofiodinepresent B. Bariumhydroxide
B. Thecomparativeantisepticefficiency C. Calciumhydroxide
C. Thesolventmediumused D. Magnesiumhydroxide
D. Alloftheabove E. Noneoftheabove
E. Noneoftheabove
145. A strong, caustic substance also known asburntlime.
140. Acalka®contains
A. Calciumcarbonate
A. Sodiumchloride B. Calciumhydroxide
B. Calciumcarbonate C. Calciumoxide
C. Potassiumcitrate D. Calciumsulfate
D. Magnesiumsulfate E. Calciumchloride
E. Ferroussulfate
146. ThecompoundcommonlyknownasPlasterofPari
141. Whatistheimpuritywhichisfoundmorefrequencyintal sisknownas
c?
A. Magnesiumsulfateheptahydrate
A. Zincoxide B. Calciumsulfate
B. Calciumoxide C. Sodiumphosphate
C. Silica D. Aluminumchloride
D. Magnesiumoxide E. Calciumcarbonate
E. Calciumsulfate
147. Butterofzincischemicallyknownas
142. Nessler'sreagent,anakalinesolutionofpotassium
tetraiodomercurate (II), is used todetect A. Zinccarbonate
B. Zincchloride
A. Arsenic C. Zincoxide
B. Ammonia D. Zinclactate
C. Zinc E. Noneoftheabove
D. Mercury
E. Silver 148. Tromdorff'sstarchisareagentusedfordetecting

143. Theonlyacidtodissolvegold A. Nitrites

B. Freechloride
A. Nitricacid C. Iodides
B. Sulfuricacid D. AandB
C. Hydrochloricacid E. Noneoftheabove
D. Selenicacid
E. Sulfuricacid
144.
INORGANICPHARMACEUTICALCHEMISTRY
149. Whatsubstancecanbeusedtopurifytalc? This gas is lighter than air cause the pitchof sounds
uttered by the vocal cord to
A. Hydrochloricacid beincreased,producingunintelligiblespeechwitha‘DonaldDuck’
B. Sulfuricacid sound
C. Zincoxide
D. Selenicacid A. Oxygen
E. Allofthese B. Carbondioxide
C. Helium
150. Which among the halogens the D. Nitrousoxide
mostpolarizable? E. Hydrogen
A. Iodine 155. Whichofthefollowingstatementsisfalseregardingactiv
B. Bromine atedcharcoal?
C. Chlorine
D. Fluorine A. Activatedcharcoalisadministeredinacharcoal-to-
E. Astatine poisonratioof5:1to10:1
B. Higherdosesofactivatedcharcoalarenecessary if
151. Fenton'stestisatestusedtodetectthepresenceof the patient ate before thepoisonoccured
C. Charcoaltabletsmaysubstitutethepowderedf
A. Chromates
ormasitisaseffective
B. Tartrates D. Repeated administration of
C. Sulfates activatedcharcoalafteranadequateinitialdoseofthe
D. Chlorides antidote appears to exert noadditional inhibition of
E. Acetates absorption of thepoison
152. Whatisthecolorofthecontainerusedforhelium? E. Noneoftheabove

A. Green 156. Aneffectiveprecipitantforbothtopicalandgastricexpos

uretophosphorusis
B. Black
C. Brown A. Cupricsulfate
D. Blue B. Sodiumphosphate
E. Red C. Calciumgluconate
153. Whatisthecolorofthecylinderthatcontainsnitro D. Ferrousoxide
usoxide? E. Potassiumchloride

A. Green 157. Whatisthemanagementofrespiratorytract

irritation caused by the inhalation ofbromine?
B. Black
C. Brown A. Inhalationofoxygen
D. Blue B. Waftingofaromaticspiritofammonia
E. Red C. Inhalationofalcoholvapor
154. D. Inhalationofwatervapor
E. Inhalationofartificialair
INORGANICPHARMACEUTICALCHEMISTRY
158. Preston'ssaltischemicallyknownas Mineralchameleonischemicallyknownas
A. Magnesiumsulfate A. Potassiumnitrate
B. Calciumchloride B. Hydratedpotassiumaluminumsulfate
C. Ammoniumcarbonate C. Potassiumhydroxide
D. Calciumcarbonate D. Potassiumpermanganate
E. Potassiumsulfate E. Potassiumsulfate
159. Thispreparationcanhastenabsorptioninthe stomach, 164. Yellowprecipitateisemployedas
increase acid gastric juicesecretionandactascarminative
A. Opthalmicantiseptic
A. Limewater B. Emetic
B. Sodawater C. Scabicide
C. Dakin'ssolution D. Expectorant
D. Dilutehydrochloricacid E. Carminative
E. Glacialaceticacid
165. Whiteprecipitateausedas
160. Pale-
yellowprecipitateobtainedafterthereactionwithsilvernitrate A. Localanti-infective
solution. B. Dustingpowder
C. Topicalanti-parasitic
A. Silverchloride D. Alloftheabove
B. Silveriodide E. Noneoftheabove
C. Sodiumbromide
166. What form of sulfur is characterized
D. Sodiumfluoride
asfine,yellow,crystalwithafaintodorandtaste?
E. Sodiumbicarbonate
161. Howe'ssolutionisasolutioncontaining A. Amorphoussulfur
B. Precipitatedsulfur
A. Sodiumhypochlorite C. Sublimedsulfur
B. Cupricsulfate D. Plasticsulfur
C. Ammoniacalsilvernitrate E. Noneofthese
D. Ammoniumchloride
E. Aluminumacetate 167. Whatarethemetalsthatcombinetoformsolder?

162. What silver compound used in 1- A. Tin andAntimony

2%dilutioninthetreatmentofvaginitiscausedbyTrichomonas B. TinandLead
vaginalisandMoniliaalbicans? C. TinandCopper
D. CopperandZinc
A. Mildsilverprotein E. CopperandLead
B. Strongsilverprotein
C. Colloidalsilverchloride 168. Whatistheuseofmercuricsalicylate?
D. Silverpicrate A. Antiseptic
E. Silvernitrate B. Anticabies
163. C. Antisyphilis
D. Pediculocide
E. Germicide
INORGANICPHARMACEUTICALCHEMISTRY
169. Which of the following statements inDalton's Whatisthetraceelementimplicatedincellular respiration
Atomic Theory are valid in the light and as antioxidant inconjunctionwithVitaminE?
ofmorerecentresearchesinatomicstructures?
A. Manganese
A. Allelementsconsistofminutediscreteparticlescalle B. Selenium
datoms C. Zinc
B. Atomsofagivenelementarealikeandhavethesamem D. Iron
ass E. Chromium
C. Atomscannotbesubdividednorthoseoneelementch
angeintoanother 174. Whatistheradioactiveelementproducedbythedecayof
D. Atomscannotbecreatednordestroyed uranium?
E. Noneoftheabove
A. Radium
170. Anessentialtraceelementwhichseemedto improve or B. Radon
normalize impaired glucosetolerance of some diabetics, C. Rubidium
elderly andmalnourishedchildren. D. Technetium
E. Argon
A. Zinc
B. Manganese 175. Auranofin,agoldcomplexisusedas
C. Copper
A. Antirheumatic
D. Chromium
B. Antibacterial
E. Iron
C. Antineoplastic
171. Whatcompoundofbismuthisusedintramuscula D. Radioopaquant
rlytotreatsyphilis? E. Noneofthese

A. Bismuthpotassiumtartrate 176. Whatistheleastpenetratingparticleemittedbyra

B. Bismuthsubcarbonate dioactiveelements?
C. Bismuthsubgallate
A. Alpharays
D. Bismuthsubnitrate
B. Betarays
E. Bismuthsubsalicylate
C. Gammarays
172. What is the mechanism by which D. AandB
ironinterfereswiththeabsorptionoftetracyclines? E. BandC

A. Oxidation 177. A deficiency of this trace element results

B. Reduction tohypochromic anemia and excessive
C. Neutralization hepaticstorageinWilson’sdisease.
D. Chelation
A. Zinc
E. Alkylation
B. Iron
173. C. Magnesium
D. Copper
E. Aluminum
INORGANICPHARMACEUTICALCHEMISTRY
178. WhattraceelementconstitutesVitaminB12? Deficiencyofthisinorganicionresultstoosteomalaciaandrena
lrickets
A. Cobalt
B. Sulfur A. Calcium
C. Selenium B. Phosphorous
D. Flouride C. Sodium
E. Iron D. Chloride
E. Iodide
179. Whatisthelevel,inmg/dLofmagnesiumpresentthebloo
dplasma? 184. Whatconditionsmayresulttohypocalce
mia?
A. 2
B. 3 A. Hypoparathyroidism
C. 5 B. VitaminDdeficiency
D. 10 C. Steatorrhea
E. 15 D. Allofthese
E. Noneofthese
180. Thistraceelementispoorlyabsorbedandneedstobeaided
byVitaminD 185. Thefourthmostabundantcationinthehumanbodyis:

A. Sodium A. Magnesium
B. Potassium B. Iron
C. Calcium C. Calcium
D. Manganese D. Manganese
E. Iron E. Sodium
181. WhatisactiveingredientpresentinCalamineloti 186. What cation exerts a powerful
on? generalanestheticactionsimilartothatproducedbychlorofo
rm when injected intramuscularly orintravenously
A. Iodine
B. Precipitatedsulfur A. Magnesium
C. Ferricoxide B. Iron
D. Cadmiumsulfide C. Calcium
E. Zincoxide D. Manganese
E. Potasium
182. Thissubstanceaddedtowholebloodtopreventclottin
gincollectedbloodsamples. 187. HowmanymEq/LofchlorinedoesRinger'sInjec
tioncontain?
A. EDTA
B. Citrate A. 3
C. Heparin B. 4
D. Warfarin C.4.5
E. Allofthese D.147
183. E.155.5
INORGANICPHARMACEUTICALCHEMISTRY
188. What compound is used in the treatmentof All of the following agents abulk-
chronic acidosis to restore increasinglaxative,EXCEPT:
bicarbonatereserveandalsoexertsadiureticeffect?
A. Castoroil
A. Sodiumbicarbonate B. Cellulose
B. Potassiumbicarbonate C. Psyllium
C. Sodiumcitrate D. Bran
D. Sodiumbiphosphate E. Noneofthese
E. Potassiumcarbonate
194. Allofthefollowingnamesaresynonymsofpotassiumcarbo
189. Which zone in the Bunsen flame shouldone heat the [Link]:
thin platinum wire which
ispreviouslycleanedbydippingintoconcentratedHCl? A. Potash
B. Pearlash
A. Upperreducingzone C. Creamoftartar
B. Upperoxidizingzone D. Saltofwormwood
C. Hottestportionoftheflame E. Noneofthese
D. Lowertemperaturezone
E. Anyofthese 195. Potassium chlorate should be handled withextreme
caution as explosions may occur whenitistrituratedwith
190. Whichofthesesubatomicparticleshavethesmallestm
ass? A. Tannicacid
B. Sulphides
A. Electron C. Reducediron
B. Proton D. Charcoal
C. Neutron E. Allofthese
D. Subatomicshell
E. Orbital 196. What potassium salt is slowly excreted bythe kidneys
and may cause hemolysis
191. Borax(Na2B4O7●10H2O)chemincallyknownas therebyirritatingthesametoproducemarkedinterstitialnephritis?
Itcanalsocausesomeconversionofhemoglobintomethemoglobi
A. Sodiumborate n.
B. Sodiumtetraborate
C. Sodiumbiborate A. Potassiumcarbonate
D. Sodiumpyroborate B. Potassiumchlorate
E. Allofthese C. Potassiumchloride
D. Potassiumhydroxide
192. Whatisthecolorofcupricoxideifcuprousoxidecoloredred? E. Potassiumsulfate
A. Blue 197. Which of the following element
B. Colorless occurhighestintheelectromotiveseriesofmetals?
C. Black
D. Green A. Aluminum
E. Yellow B. Calcium
193. C. Bismuth
D. Iron
E. Lithium
INORGANICPHARMACEUTICALCHEMISTRY
198. Which of the following metals will WhatisthecompoundpresentinGregory'sPowder?
reactwithacidstoproducehydrogen?
A. Ammoniumhydroxide
A. Zinc B. Magnesiumoxide
B. Copper C. Sodiumcarbonate
C. Silver D. Calciumsulfate
D. Mercury E. Potassiumchloride
E. Anyoftheabove
204. AllofthefollowingsubstancesarepresentinAguaregia,E
199. A colorless, flammable toxic gas with XCEPT
theformulaPH3
A. Hydrochloricacid
A. Phosphane B. Chlorine
B. Hypophosphorusacid C. Nitricacid
C. Hypophosphoricacid D. Nitrosylchloride
D. Phosphoricacid E. Sulfuricacid
E. Phosphor
205. Whatistheuseofbariumchloridewhentakeninternally?
200. Whatisthecoloroftheprecipitateformedupon the
reaction of zinc chloride reacts withhydrogensulfide A. Treatmentofsyphilis
B. Germicide
A. Black C. Treatmentofheart-block
B. Yellow D. Managementofpain
C. Brickred E. ImagingoftheGIT
D. White
E. Brown 206. Niterischemicallyknownas

201. Corrosivesublimateischemicallypresenteda A. KNO3

s B. KNO2
C. NaNO3
A. 4Bi(OH)2NO2●BiO(OH) D. NaNO2
B. HgCl2 E. N2O
C. NaOH
D. KOH 207. Chilesaltpeterinchemicallyknownas
E. HgCl A. KNO3
202. Copper is associated to promote B. KNO2
betterassimilationof C. NaNO3
D. NaNO2
A. Iron E. N2O
B. Calcium
C. Zinc
D. Magnesium
E. Potassium
203.
INORGANICPHARMACEUTICALCHEMISTRY
208. WhatisthecompoundpresentinGoulard'sex Whatisthebestdefinitionofrateofreaction?
tract?
A. Thetimeittakestouseupallthereactants
A. Aluminumsubacetate B. Therateatwhichallthereactantareusedup
B. Leadsubacetate C. Thetimetakesforoneofthereactantstobeusedup
C. Arsenictrioxide D. Theincreaseinconcentrationofaproductperu
D. Antimonypotassiumtartrate nittime
E. Mercurychloride E. Noneofthese

209. What is the color of flame produced 214. What composes the universal
bysodiumwhenviewedunderthecobaltglass? antidoteotherthanactivatedcharcoalandtannicacid?

A. Crimson A. MgCl2
B. Purple B. MgCO3
C. Green C. Mg(OH)2
D. Yellow D. MgO
E. Blue E. MgSO4

210. WhatisthenewSIunitforradioactivity? 215. Bordeuxmixturecontainswhatsalt?

A. Curie A. Cupricsulfate
B. Roentgen B. Magnesiumsulfate
C. Rad C. Seleniumsulfide
D. Becquerel D. Silvernitrate
E. Milligram E. Calciumsulfate

211. Whatisthewatercontaminantthatcausesitai-itaidisease? 216. WhattypeoflaxativeincreasesosmoticloadoftheGl

T?
A. Barium
B. Cadmium A. Bulk-forminglaxative
C. Aluminum B. Emollientlaxative
D. Beryllium C. Salinecathartic
E. Mercury D. Stimulantlaxative
E. Allofthese
212. Whatelementresiststheattackofallacidwiththeexemp
tionofHF? 217. ThefollowingparameterscancauseashiftofequilibriumEX
CEPT
A. Selenium
B. Aluminum A. Catalyst
C. Silicon B. Concentration
D. Copper C. Pressure
E. Zinc D. Temperature
213. E. Noneofthese
INORGANICPHARMACEUTICALCHEMISTRY
218. What quantum number describes Whatinthephenol-containingcompoundisolatedfromcloveoil?
thespatialorientationoftheelectroncloudwithrespecttot
hethreeareasinspace? A. Eugenol
B. Resorcinol
A. Spinquantumnumber C. Cresol
B. Magneticquantumnumber D. Hexylresorcinol
C. Principalquantumnumber E. Menthol
D. Azimuthal
E. Noneofthese 224. GreenVitriolischemicallyknownas

219. What compound is known as King'syellow? A. Coppersulfate

B. Magnesiumsulfate
A. Potassiumpermanganate C. Sodiumsulfate
B. Chromicacid D. Ferroussulfate
C. Cadmiumsulfide E. Cuprousoxide
D. Leadchromate
E. LeadAcetate 225. Whatisthecompoundpresentinchalybeatep
ills?
220. What is the mechanism of action
ofthiabendazole? A. Ferroussulfate
B. Ferrouscarbonate
A. ParalysisduetoGABAreceptoroccupation C. Aluminumcarbonate
B. Inhibitionofcelldivision D. Leadcarbonate
C. Phagocyticattackonworms E. Ferrousgluconate
D. Decreasedglucoseuptake
E. Interfereswithproteinsynthesis 226. Whatisthebestantidoteforphosphoruspoisoning?

221. Whatisthecommonadversedrugreactionexperiencewith A. NaCl

streptomycinandotheraminoglycosideantibiotics? B. EDTA
C. NaHCO3
A. Goiterogenicity D. MgSO4
B. Ototoxicity E. CuSO4
C. Hyperglycemia
D. Hepatotoxic 227. InREDOXreaction,thereducingagentis
E. Neurology A. Isoxidized
222. Whatis/areuse/sofaluminumsulfate? B. Isreduced
C. Gainselectrons
A. Antiseptic D. Decreasedinoxidationstate
B. Astringent E. Noneoftheabove
C. Carminative
D. AandB
E. A,B,C
223.
INORGANICPHARMACEUTICALCHEMISTRY
228. Whichofthefollowingglasstypemakesuseofwaterat WhichofthefollowingitemsisNOTauseoflunarcaustic?
tacktesttype?
A. Anti-gonococcalagent
A. TypeI B. Wartremoval
B. TypeII C. Cankersoresapplication
C. TypeIII D. Antiscabies
D. TypeIV E. Noneofthese
E. TypeNP
234. Fluorineinhibitscariesformationvia
229. Whyshouldgreatcarebeobservedinhandlingcausti
cpotash? A. Decreaseacidsolubilityofenamel
B. Bacterialinhibition
A. Iteasilyoxidizes C. Increasesolubilityofenamel
B. Itmaycauseanexplosion D. AandB
C. Itrapidlydestroystissues E. BandC
D. Itformsadeliquescentmixturewhenexposureair
E. Itiseasilyinactivated 235. WhichamongthefollowingstatementsaboutleadisN
OTtrue?
230. Thisisaneffectiveantidoteforthetreatmento
fpoisoningbycopper A. Itprecipitatesprotein
B. Itsactioniscumulative
A. Penicillamine C. Insolubleleadsaltsareconvertedtoreadchloridein
B. Dimercaprol thestomach
C. Lugol'ssolution D. Itburnswithbluishflame
D. EDTA E. Noneoftheabove
E. NaCl
236. Burnettsyndromeisassociatedwiththeprolongeduse
231. WhatisthechemicalcompositionofRedprecipitate? of

A. Cuprousoxide A. Calciumcontainingantacid
B. Leadsulfide B. Magnesiumcontainingantacid
C. Mercuricoxide C. Aluminiumcontainingantacid
D. Berylliumoxide D. Simethiconecontainingantacid
E. Ferroussulfate E. Sodiumbicarbonateantacid

232. Which among the following element inNOT a 237. Whatisthemajorsideeffectassociatedwithsalinecat

member of Group IV of the periodictable? hartics?

A. Antimony A. Excessivelossofbodyfluids
B. Titanium B. Convulsions
C. Carbon C. Cardiacdisorder
D. Tin D. Constipation
E. Lead E. Nauseaandvomiting
233.
INORGANICPHARMACEUTICALCHEMISTRY
238. Whatisthecontraindicationofallmercurials? WhatelementisdetectedbyGutzeittest?

A. Cardiacedema A. Antimony
B. Liverdamage B. Calcium
C. Renaldamage C. Tin
D. Seizure D. Arsenic
E. Noneofthese E. Mercury

239. WhichamongthefollowingcompoundscomposeLact 244. Chromium 51 is supplied as

atedRinger’ssolution? sodiumchromatesolutionorinjectionwhichisused

I. Sodiumchloride A. TolabelRBCs
II. Potassiumchloride B. IntheDiagnosisofvariousinfections
III. Magnesiumchloride C. InCisternography
IV. Calciumchloride D. InVerntriculography
V. Calciumlactate E. Noneoftheabove
VI. Sodiumlactate
245. Gold-198usedinthetreatmentof
A. I,II,III A. Perniciousanemia
B. I,II,III,IV B. Rheumatoidarthritis
C. I,II,III,IV,V C. Cancer
D. I,II,IV,V D. Thyroidfunctioning
E. I,II,IV,VI E. Thrombocytopenia
240. Whiteleadischemicallyknownas 245. What is the use of Calcium 47 when it
A. PbS issuppliedascalciumchlorideintheformofaninjection?
B. PbCO3 A. Inthediagnosisofperniciousanemia
C. PbSO4 B. Asurinaryandfecalmarker
D. Pb C. Forpancreaticscintigraphy
E. PbCl2 D. Allofthese
241. Sodiumacetateisusedas E. Noneofthese

A. Urinaryacidifier 247. 1Becquerelisequivalentto

B. Calciumreplenisher A.
-11
2.7x10 curie
C. Forperitonealdialysisfluids B.
-10
2.7x10 curie
D. Antioxidant C. 2.7x10-8curie
E. Antiseptic D. 2.7x10-5curie
242. Wilson'sdiseaseisaconditionofexcessstorageof E. 2.7x10-12curie

A. Fe
B. Zn
C. Cu
D. Cd
E. Al
243.
INORGANICPHARMACEUTICALCHEMISTRY
248. Thefollowingcompoundsareemployedasantidoteforcya Theonlysyntheticandradioactivehalogen:
[Link]
A. Fluorine
A. Sodiumnitrite B. Chlorine
B. Sodiumthiosulfate C. Bromine
C. Sodiumhypochlorite D. Astatine
D. Amylnitrite E. lodine
E. Noneofthese
254. Whatistheuseofmanganesedioxide?
249. Brimetoneischemicallyknownas
A. Oxidizingagent
A. Sulfur B. Antiseptic
B. Silicon C. Treatmentofammenorrhea
C. Lead D. Treamentofchlamydiainfection
D. Mercury E. Treatmentofacneandboils
E. Beryllium
255. What is the force that holds
250. Rochellesalt,usedmedicinallyasalaxative,hast atomstogetherorrestrainsthemotionofatomswithinamolecule?
hechemicalformulaof
A. Valence
A. KHC4H4O5 B. Oxidationnumber
B. Na3AlF6 C. Chemicalbond
C. NaKC4H4O6 D. Ionizationpotential
D. CaSO4●H2O E. Electronaffinity
E. CuSO4●5H2O
256. Whatisthepredominantionintheintracellularfl
251. WhatistheacidpresentinGentianElixir? uid?
A. Sulfuricacid A. Sodium
B. Phosphoricacid B. Potassium
C. Dilutehydrochloricacid C. Magnesium
D. Nitricacid D. Calcium
E. Aceticacid E. Iron
252. What compound is present in 257. What halogen possesses
Bordeauxmixture,analgaecide- ananticarcinogeniceffect?
fungicideagentusedinswimmingpools?
A. Fluorine
A. Zinc B. Chlorine
B. Copper C. Bromine
C. Lead D. Iodine
D. Sulfur E. Astatine
E. Chlorine
253.
INORGANICPHARMACEUTICALCHEMISTRY
258. A synthetic, radioactive noble gas is usedin the This ion is used very effectively
treatment of cervical cancer and orallesions: asastringent,protectiveandantiperspirant

A. Argon A. Mg++
B. Indium B. Al+++
C. Radon C. Zn++
D. Xenon D. Cu++
E. Helium E. Pb++
259. Artificialairisusedtherapeuticallytoalleviate 264. What in the chemical formula of
difficult respiration. What is thecomposition? Tartaremetic,aneffectiveanti-schistosomalagent?

A. 50%Oxygenand40%Helium A. KHC4H4O6
B. 20%Oxygenand80%Helium B. NKC4H4O5
C. 20%Heliumand80%Oxygen C. KSbOC4H4O6●½H2O
D. 80%Kryptonand20%Helium D. Na2C4H4O6
E. 80%Oxygenand20%Hydrogen E. KSbOC4H4O6
260. Pyrogen-freedistilledwateris 265. This inert gas is used to replace air
incontainersofsubstancesthatareadverselyaffectedbyai
A. PurifiedwaterUSP roxidation
B. Distilledwater
C. Waterforinjection,USP A. Helium
D. SterileWaterforInjection,USP B. Neon
E. BacteriostaticWaterforinjection,USP C. Nitrogen
D. Hydrogen
261. Whatistheonlyofficialbariumsaltusedinmedicine as a E. Argon
radiopaque substance
inroentgenographicexaminationoftheGItract? 266. Whichofthefollowingcompoundsisasystemicanta
cid?
A. Bariumchloride
B. Bariumsulphate A. Magnesiumtrisilicate
C. Bariumcitrate B. Sodiumbicarbonate
D. Bariumphosphate C. Aluminumhydroxide
E. Bariumhydroxide D. Dihydroxyaluminumphosphate
E. Noneoftheabove
262. WhatisthemetalpresentinGuignard’sreagent, a
valuable reagent used in organicsynthesis? 267. Thefollowingcompoundsareemulsifyingagent/surfact
antsEXCEPT:
A. Zinc
B. Magnesium A. Benzalkoniumsulfate
C. Iron B. Sodiumsulfate
D. Aluminum C. Sodiumlaurylsulphate
E. Lead D. Tragacanth
263. E. Noneofthese
INORGANICPHARMACEUTICALCHEMISTRY
268. Fromthepharmaceuticalstandpoint,themost Hartshornischemicallyknownas
important coordination compounds arethoseof
A. (NH4)2CO3
A. Fe B. LiquidNH3
B. Mn C. GaseousNH3
C. Zn D. NH4Cl
D. Al E. NH4I
E. C
274. WhatisthechemicalformulaofSaltpeterorsalitre,ame
269. Nuclides of different elements atpreservative?
havingidenticalmassnumbersbutdifferentatomicnumber
saretermedas A. KNO2
B. NaNO3
A. Isotopes C. NaNO2
B. Isobars D. KNO3
C. Isotones E. KHCO3
D. Isomers
E. Epimers 275. The bond that is formed when positivelycharged
particles are combines with
270. Whatsaltofcalciumformsthebasisofthehumanskeleton? negativelychargedparticlestoformacompoundisknownas

A. CaCO3 A. Ionicbond
B. CaSO3 B. Covalentbond
C. CaC2O4 C. Coordinatebond
D. Ca3(PO4)2 D. Vanderwaalsbond
E. CaSO4 E. Peptidebond

271. Nuclidesofdifferentelementshavingthesamenumbers 276. Thelawwhichstatesthatpressureisdirectly

ofneutronsaretermedas proportional to temperature, if
thevolumeisconstantisknownasthe
A. Isotopes
B. lsobars A. Boyle'sLaw
C. Isotones B. Avogadro'sLaw
D. Isomers C. Charles’Law
E. Epimers D. Gay-Lussac’sLaw
E. Henry’sLaw
272. What is the coloidal silver proteincontaining7-
8%ofsilver,thatisusedforthetreatmentofear,noseandthr 277. The energy required to remove
oatinfections? theelectronfromtheneutralatomistermedas

A. Argyrol A. Electronaffinity
B. Collargol B. Kineticenergy
C. Protargol C. Ionizationpotential
D. Solargantum D. Electricalenergy
E. Lunarcaustic E. Electronnegativity
273.
INORGANICPHARMACEUTICALCHEMISTRY
278. Amalgamsarealloysof Allofthefollowingaremechanismofantimicrobialaction,
EXCEPT:
A. Iron
B. Silver A. Oxidation
C. Copper B. Halogenation
D. Mercury C. Hydrolysis
E. Tin D. Proteinprecipitation
E. Noneofthese
279. Whichisnotpossibleaccordingtoquantumme
chanics? 284. Whichsolutionissuitableforapplicationtowound?
A. 2d A. ModifiedDakin'ssolution
B. 3d B. Dakin'ssolution
C. 4d C. Labarraquesolution
D. 5d D. Chlorinatedlime
E. Noneofthese E. SugarofLead
280. Theseelementsformbasicanhydrides,EXCEPT 285. Whatmetalisusedinthesurgicalrepairofbones,musclesa
ndtissues?
A. K
B. Na A. Ti
C. Mg B. V
D. Ca C. Ta
E. S D. Mo
E. Pt
281. Whatdoesthetermhalogenmean?
286. Whatistheofficialwaterusedintheextemporane
A. Saltproducer ous compounding of
B. Acidformer theparenteralsforeitherIVorIMinjection?
C. Waterformer
D. Niterproducer A. Waterforinjection,USP
E. Noneofthese B. Bacteriostaticwaterforinjection,USP
C. Sterilewaterforinjection,USP
282. Theseionsareusedasalkalinizerinmetabolicacido
D. Purifiedwater,USP
sis,EXCEPT
E. Waterforirrigation,USP
A. Bicarbonate 287. Whichofthefollowingisnativehydrousmagnesiumsili
B. Biphosphate cate?
C. Acetate
D. Citrate A. Talc
E. Noneofthese B. Pumice
283. C. Kaolin
D. Bentonite
E. Clay
INORGANICPHARMACEUTICALCHEMISTRY
288. Epsomsaltisusedas: What does the syllable “bi” in
sodiumbicarbonateandsodiumbiphosphateindicate?
A. Antiphlogistic
B. Anticonvulsant A. Thecompoundsandacidsalts.
C. Cathartic B. Thecompoundcomposedoftwoelements
D. Allofthese C. Thecompoundsareneutralsalts
E. Noneofthese D. Thecompoundsarebasicsalts
E. Noneofthese
289. Whatinorganicionisessentialforbloodcoagulation?
294. Oxideoftypicallynon-metallicelementsare
A. Ca+2
B. Na+1 A. Neutral
C. Fe+3 B. Basic
D. Mg+2 C. Acidic
E. K+1 D. Ampotheric
E. Noneofthese
290. Which is not a component of Ringer’sinjection?
295. Whatenzymecontainsbothcopperandiron?
A. NaCI
B. KCl A. Trypsinase
C. MgCl2 B. Cytochromeoxidase
D. CaCl2 C. Peroxidase
E. Fe D. Oxidase
E. Reductase
291. AllofthefollowingarescabicideEXCEPT
296. Whatvitaminincreasestheabsorptionofiron?
A. Sublimedsulfur
B. Sulfurdioxide A. VitaminE
C. Precipitatedsulfur B. VitaminD
D. Sulfuratedpotash C. VitaminC
E. Whitesulfide D. VitaminA
E. VitaminK
292. Positivelychargedionsarecalled
297. Whatisacommonsideeffectofmagnesium
A. Protons
-containingantacids?
B. Neutrons
C. Cations A. Constipation
D. Anions B. Irritatingeffect
E. Ions C. Laxative
293. D. Nausea
E. Pruritus
INORGANICPHARMACEUTICALCHEMISTRY

298. Whatisthemostimportantplasmabuffer?
A. HPO4-2
B. H2PO4-
C. HCO3-
D. H2CO3
E. Noneoftheabove
299. Buffersfoundinthecellsandkidneys
A. HCO3-/H2CO3
B. HPO4-/H2PO4-
C. Plasmaprotein
D. Hemoglobin
E. Boricacid
300. ThefollowingaretrueaboutCalcium,EXCEPT

A. Essentialforbloodclotting
B. 99%foundinthebones
C. Foundintheintracellularfluids
D. Absorbedfromtheupperpartofsmallintestines
E. Formssolublesaltswithchloride
For numbers 1-5, refer to the structure of a beta-lactam antibiotic. C.) Attaching a halogen to the parent compound
D.) Substituting the parent compound with a lipophilic group
E.) Increasing the molecular weight
1. The functional group attached to the acyl amino group is
called a/an: 7. Sodium pump is an example of
A.)enzyme-linked tyrosine kinase receptor
A.) Phenoxyethyl B.) G-protein coupled receptor
B.) Isoxazoyl C.) Ion- channel
C.) Imidazole D.)Gene transcription-linked receptor
D.) Benzyl E.) None of the above
E.) Methoxypheny
8. This is an approach in drug discovery wherein there is already
2. Halogen substituents are best placed in what position? an existing drug that can be used to identify a new lead
compound?
A.) 1,2-substitution
B.) 1,3-substitution A.) Random Screening
C.) 1,4-substitution B.) Molecular Docking
D.) Both A and B C.) Parent compound modification
E.) Both A and C D.) Biotechnology techniques
E.) Rational Drug Design
3. This antibiotic is primarily indicated for what type of
infection? 9. Azeotropic distillation of benzene is done in what
concentration of ethanol?
A.) Klebsiella
B.) Enterobacter A.) 95%
C.) Psudomonas B.) 70%
D.) Staphylococci C.) 50%
E.) Streptococi D.) 99%
E.) 10%
4. Adding more than 1 chloride atoms in the structure confers
what modification on the pharmacokinetic profile of the drug? 10. Radical reactions may also proceed using this reagent

A.) Liberation A.) Bromine water

B.) Absorption B.) Hydrogen peroxide
C.) Distribution C.) Nitric acid
D.) Metabolism D.) Sodium oxalate
E.) Excretion E.) Potassium bitartrate

5. What is the role of chloride atoms in the structure?

A.) Increase the susceptibility to penicillinase

B.) Increasing the plasma concentration
C.) Acid resistance property
D.) Increase in parenteral absorption
E.) Increase in oral absorption

For numbers 11-14, refer to the series of the reaction

6. Preservatives like parabens increase their preservative 11. What is the reagent needed for the first reaction?
property by
A.) NaOH/ Oxidizing agent
A.) Reducing the parent compound B.) CH3 Cl/AlCl3
B.) Decreasing molecular weight C.) HNO3/H2SO4
D.) NaOH/ Reducing agent
E.) CH3Br/NaNH2 A.) Anisole
B.) Toluene
12. The product formed with the reaction is C.) Aniline
D.) Xylene
A.) Benzyl alcohol E.) Anethole
B.) Phenol
C.) Benzoic acid 18. Which of the following compounds can be use to synthesize
D.) Xylene primary alcohol?
E.) Anisole
A.) Propane
13. The reagent needed for the reaction to proceed is B.) Formaldehyde
C.) 3-chloropentane
A.) CH3Br/NaNH2 D.) Acetone
B.) NaOH/Reducing agent E.) Ethanamine
C.) CH3COCl/AlCl3
D.) HNO3/H2SO4 19. Which of the following cephalosporin is excreted in bile?
E.) NaOH/ Oxidizing agent
A.) Cefixime
B.) Cefotaxime
14. The reagent needed for the reaction to proceed is C.) Ceftriaxone
D.) Moxalactam
A) NaOH/Oxidizing agent E.) Loracarbef
B) CH3Br/NaNH2/NO2
C) H2O/H2SO4 20. What is the product of aromatic hydroxylation of this drug?
D) NaOH/Reducing agent
E) NBS

15. When a carbonyl group reacts with a secondary amine, what 21. Preservatives use for molds
will be the resulting product?
A.) Ethylparaben
A.) Imine B.) Methylparaben
B.) Amide C.) Butylparaben
C.) Tertiary amine D.) Propylparaben
D.) Enamine E.) Isopropylparaben
E.) Secondary amine

22. Which is true about drug absorption?

16. The addition of hydrogen molecule to an alkene is catalyzed I. For weakly acidic drug, it must e in its unionized form
by what metal? II. For weakly acidic drug, it must be in its ionized form
III. For weakly basic drug, it must be in its unionized form
A.) Silver IV. For weakly basic drug, it must be in its ionized form
B.) Palladium
C.) Berrylium A.) I, II, III
D.) Gallium B.) I and III
E.) Osmium C.) II and IV
D.) III and IV
17. Methoxybenzene is also known as _____ E.) I and III
 D.) II and III
23. This anti-convulsant compound is susceptible to what E.) III and IV
metabolic pathway?
28. Aztreonam can elevate this enzyme
A.) Aromatic hydroxylation
B.) Methylation A.) Creatinine kinase
C.) Sulfate conjugation B.) Pyruvate kinase
D.) Oxidative deamination C.) Alanine aminotransferase
E.) GSH conjugation D.) Creatinine phosphokinase
E.) Thrombin
For numbers 24-26, refer to the general structure of penicillin
For numbers 29-33, Refer to the structure of this antibacterial agent
24. Which of the following will confer resistance against beta
lactamases when synthesizing analogs of penicillin? 29. The functional group in the box is an additional chemical
entity of this drug that makes it a prodrug, what is the
A.) Halogens probable reason of adding that moiety to the parent
B.) Ring deactivators compound?
C.) Electron withdrawing group
D.) Bulky group A.) Increase in absorption
E.) Ring activators B.) Increase in palatability
C.) Decrease in Protein binding
25. What functional group is being modified if formulation into a D.) Increase in solubility
salt is needed? E.) Decrease in absorption

A.) Amide
B.) Carboxylic acid 30. The main functional group of this prodrug is a/an
C.) Carbonyl
D.) Alkyl A.) Amide
E.) 225g B.) Nitro
C.) Alcohol
D.) Ester
E.) Acyl halide

31. When the drug will undergo metabolism, which of the

following enzymes will act on it?

26. What is the functional group attached to the beta lactam A.) Ligases
ring? B.) Hydrolases
C.) Transferases
A.) Aryl amide D.) Isomerases
B.) Acyl amide E.) Lyases
C.) Polyamide
D.) Carboxyamide 32. When the drug is acted upon by different enzymes during its
E.) Phenylamide metabolism, what is/are the products?

27. Which of the following is true on ideal antiseptic? A.) Alcohol

I. Low toxicity B.) Amide
II. Sustained and rapid lethal action against microorganisms C.) Carboxylic acid
III. High surface tension D.) A and B
IV. Non-irritating and non-allergenic E.) B and C

A.) I, II, IV 33. This drug is an example of

B.) III only
C.) I, II, III, IV A.) Cell wall synthesis inhibitor
 B.) Cell membrane disruptor D.) CNS depression
C.) Protein synthesis inhibitor E.) Sodium channel blockage
D.) Nucleic acid synthesis inhibitor
E.) Alkylating agent 40. The compound is an example of what class of drugs?

34. The compound use to identify the partition coefficient in- A.) Anesthetic
vitro B.) Barbiturate
C.) Sedatives
A.) Tert-butyl alcohol D.) Analgesic
B.) Phenol E.) Anxiolytics
C.) Isopentyl alcohol
D.) N-octanol 41. The absorption of this compound is governed by what
E.) Benzyl alcohol equation?

35. Isoniazid is metabolized by humans principally by A.) Noyes-Whitney equation

B.) Fick’s Law of Diffusion
A.) Aceylation C.) Beer’’s Law
B.) Deamination D.) Henderson-Hasselbalch equation
C.) Methylation E.) None of the above
D.) Conjugation
E.) Oxidation 42. This compound is derived from the destructive distillation of
castor oil and it is use as a keratolytic agent
36. The total affinity of the ligand to its receptor
A.) Salicylic acid
A.) Intrinsic activity B.) Undecylanic acid
B.) Agonistic activity C.) Benzoic acid
C.) Avidity D.) Chrysarobin
D.) Antagonistic activity E.) Propionic acid
E.) Agonistic affinity 43. The following are example of G protein coupled receptors,
except

37. Dimethylbenzene is also known as A.) GABA receptors

B.) Beta-2 receptors
A.) Anisole C.) Muscarinic receptors
B.) Aniline D.) Alpha -1 receptors
C.) Xylene E.) Beta -1 receptors
D.) Phenol
E.) Ethylene 44. DNA Alkylating agent binds to its target by means of what
bond?
For numbers 38-41, refer to the structure below
A.) Hydrogen bonding
38. The type of bond that exists in the structure B.) Electrostatic bonding
C.) Hydrophobic bonding
A.) Amide bond D.) Ionic bonding
B.) Ether bond E.) Covalent bonding
C.) Tert-amine bond
D.) Ester bond 45. In the presence of a full agonist, a partial agonist becomes
E.) Glycosidic bond
A.) Agonist
39. This compound may produce the following effects, except B.) Antagonist
C.) Partial agonist
A.) Vasoconstriction D.) Inverse agonist
B.) Bradycardia E.) No effect
C.) Metallic taste
46. A long-acting HMG-CoA reductase inhibitor A.) Substitution
B.) Elimination
A.) Rosuvastatin C.) Radical reactions
B.) Lovastatin D.) Addition
C.) Fluvastatin E.) Combustion
D.) Simvastatin
E.) Pravastatin 53. Alkylation of aminobenzene will likely proceed to what
position?
47. This is the most important CYP 450 isozyme that is
responsible for the metabolism of almost 50% of the drugs A.) Ortho position
available in the market B.) Meta position
C.) Para position
A.) CYP 2D6 D.) Both A and B
B.) CYP 3A4 E.) Both A and C
C.) CYP 2A9
D.) CYP 1A2 54. This is a derivative of two carboxylic acids, in which the
E.) CYP 2D10 compound is formed by the removal of one molecule of
water in two RCOOH
48. A theory that advances the idea that maximum
pharmacologic effect can be obtained if all the receptors are A.) Ether
occupied B.) Acid anhydride
C.) Amide
A.) Hypothesis of Paton D.) Acyl halide
B.) Lock and Key Theory E.) Ester
C.) Hypothesis of Clark
D.) Induced fit theory
E.) Hypothesis of Ariens & Stephenson For numbers 55-58, Refer to the structure of Bricanyl®
49. The anti-angina effect of nitrates is primarily due to the
release of what gas?
55. The drug is a derivative of
A.) Nitrous oxide
B.) Dinitrogen oxide A.) Catechol
C.) Nitrogen dioxide B.) Phenol
D.) Nitric oxide C.) Xylene
E.) Dinitrogen dioxide D.) Hydroquinone
E.) Resorcinol
50. Diuretic that acts on the distal convulated tubule
56. The compound is not affected by which enzyme during its
A.) Indapamide metabolism?
B.) Furosemide
C.) Ethacrinic acid A.) COMT
D.) Acetazolamide B.) MAO
E.) Spironolactone C.) Carboxylases
D.) Both A and B
51. What is 1,4- dihydroxybenzene? E.) Both A and C

A.) Catechol 57. The compound is a selective agonist of what receptor?

B.) Phenol
C.) Xylene A.) Alpha 1
D.) Hydroquinone B.) M1
E.) Resorcinol C.) Beta 1
D.) Beta 2
52. Halogenation of alkanes is possible in what type of reaction? E.) N1
 58. The compound is used to manage 64. The binding affinity of the compound to its receptor is highly
influenced by_______ in its structure
A.) Hypertension
B.) Asthma A.)Benzene ring
C.) Glaucoma B.) Chloro substituted benzene ring
D.) Arrhythmia C.) Carbonyl moiety
E.) Hypotension D.) Imidazole ring
E.) Seven membered heterocyclic nitrogen ring
59. Benzene undergoes what type of reaction?
65. Increase the concentration of _______ ions in the cell
A.) Nucleophilic substitution makes this drug a sedative - hypnotic.
B.) Electrophilic addition
C.) Electrophilic substitution A.) Calcium
D.) Radical reactions B.)Chloride
E.) Nucleophilic addition C.) Phosphate
D.) Potassium
60. Which of the following carbocation intermediate is the most E.) Sodium
stable?

A.) Primary
B.) Secondary
C.) Tertiary 66. An essential moiety for this compound to exert its sedative
D.) Quarternary hypnotic effect
E.) None of the above
A.) Benzene ring
61. Regioselectivity of an organic reaction in which the B.) Chloro substituted benzene ring
orientation of the substituents stabilizes the product is C.) Carbonyl moiety
governed by D.) Imidazole ring
E.) Seven membered heterocyclic nitrogen ring
A.) Le Chatelier’s Principle
B.) Markovnikov’s Rule 67. The acetylation of morphine yields
C.) Heck Reaction
D.) Hund’s Rule A.) Codeine
E.) Pauli’s Principle B.) Papaverine
C.) Noscapine
62. An enol is not a stable compound because it undergoes D.) Heroin
E.) Thebaine
A.) Electrophilic attack
B.) Hydrophobic attack 68. Primidone is a prodrug that is converted into
C.) Hydrophilic attack
D.) Hydrogen shift A.) Entacapone
E.) Tautomerization B.) Diazepam
C) Phenobarbital
For numbers 63-66, refer to the structure of an anxiolytic drug D.) Carbamazepine
E.) Aminophylline
63. The affinity of the drug to the receptor
exerts an anxiolytic and hypnotic effects For numbers 69-72, Refer to the structure of Zovirax

A.) Glutamate 69. The structure of Zovirax is an analog of

B.) Histamine
C.) Gamma-aminobutyric acid A.)Thymine
D.) Glycine B.) Adenine
E.) Dopamine C.) Guanosine
D.) Uracil
E.) Cytosine 76. Carbamazepine undergoes what Phase I metabolism reaction?

70. What is the difference of the structure of Zovirax to the A.) Aromatic hydroxylation
conventional Nucleic acid base? B.) Olefinic carbon oxidation
C.) Oxidative deamination
A.) It contains a ribose moiety D.) Allylic carbon oxidation
B.) It contains a deoxyribose moiety E.) Reduction of the - OH group
C.) It contains an open sugar moiety
D.) There is a substituted amino group 77. Thiopental is being converted into pentobarbital upon
E.) The hydroxyl group is not attached in the oxygen atom metabolism by what pathway?

71. The structure of Zovirax® competitively inhibits what A.) Oxidation

enzyme? B.) Desulfuration
C.) Dealkylation
A.) DNA polymerase D.) Reduction
B.) Reverse transcriptase E.) Direct amine conjugation
C.) Ligase
D.) RNA polymerase
E.) Protease
78. Which of the following is true about penciclovir?
72. Zovirax® is effective against the strain of
A.) The structure is similar to acyclovir, except with the side of
A.) Varicella oxygen which is replaced by a carbon and a hydroxyl group
B.) HSV B.) Short half life in tissues compared to acyclovir
C.) Vesicular Slomatitis Virus C.) Competes for the viral RNA Polymerase and inhibits its
D.) All of the above synthesis
E.) None of the above D.) It acts as a chain terminator
E.) All of the above
73. In phenols, substitution at _______ position increases
bactericidal activity 79. The first type of drugs for HIV to be available

A.) Ortho A.) NNRTI

B.) Meta B.) NRTI
C.) Para C.) Entry inhibitors
D.) All of the above D.) Protease inhibitors
E.) None of the above E.) Integrase inhibitors

74. C3H6O can be a/an 80. Which of the following HIV drugs is also used for Hepatitis B
infection?
A.) Ketone
B.) Ether A.) Azidothymidine
C.) Aldehyde B.) Saquinavir
D.) Both A and B C.) Didanosine
E.) Both A and C D.) Lamivudine
E.) Efavirenz
75. Zero order drug metabolism
81. Metabolic disorder is commonly seen in what type of HIV
A.) Saturated Kinetics drugs?
B.) Rate of metabolism is in constant concentration
C.) Rate of metabolism is not over time due to the presence of A.) Integrase inhibitors
enzymes B.) Protease inhibitors
D.) Dose dependent C.) NNRTI
E.) Constant fraction of the drug is metabolize D.) NRTI
E.) Entry inhibitors
 catalyst is needed for the reaction to proceed?
82. Acylation of the Ring II of aminoglycosides produces
______ A.) Lewis acid
B.) Bronsted acid
A.) Amikacin C.) Lewis base
B.) Streptomycin D.) Arrhenius base
C.) Tobramycin E.) Bronsted base
D.) Gentamicin
E.) Kanamycin 89. Sulfonamides are synthetic analogs of:

83. Coordination of what metal in tetracycline structure A.) Gamma aminobutyric acid
increases its activity? B.) Para amino benzoic acid
C.) Tricarboxylic acid
A.) Iron D.) Sulfonic acid
B.) Manganese E.) Carbolic acid
C.) Cobalt 90. Compounds with two or more chiral centers are termed as
D.) Palladium
E.) Nickel A.) Epimers
84. Glycopeptides exert their mechanism of action via B.) Enantiomers
C.) Stereoisomers
A.) Inhibition of 30s ribosomal subunit D.) Diastereomers
B.) Inhibition of cell wall synthesis E.) Constitutiona Isomers
C.) Inhibition of 50s ribosomal subunit
D.) Inhibition of DNA gyrase For numbers 91-95, Refer to the structure below
E.) Inhibition of cell membrane synthesis
91. This drug may likely bind to what protein?
85. Which if the following cephalosporins can cross the blood
brain barrier? A.) Albumin
B.) Alpha glycoprotein
A.) Cefprozil C.) Ubuquitin
B.) Cefuroxime D.) Globulin
C.) Cefalexin E. Bilirubin
D.) Cefmetazole
E.) Cefazolin 92. What is the IUPAC name of the drug?

86. This agent is used to chelate copper in which an excess A.) Octanoic acid
amount causes Wilson's disease B.) 2-propylpentanoic acid
C.) 4-propylpentanoic acid
A.) EDTA D.) 1-butylbutanoic acid
B.) Dimercaprol E.) 2-methylheptanoic acid
C. Penicillamine
D.) BAL 93. This drug may likely affects what neurotransmitter?
E.) Deferoxamine
A.) GABA
87. This class of penicillin contains a benzyl moiety that is B.) Dopamine
responsible for its acid labile property C.) Glutamate
D.) Norepinephrine
A.) Penicillin V E.) Serotonin
B.) Oxacillin
C.) Piperacillin 94. This drug affects what type of ion gated channel?
D.) Methicillin
E.) Penicillin G A.) Sodium
B.) Potassium
88. In the Freidles Craft Alkylation of Aromatic rings, what C.) Calcium
D.) Both A and B
E.) Both A and C 101. Decarboxylation of L- Dihydroxyphenylalanine produces

95. This drug is a powerful _____ A.) Tyrosine

B.) Epinephrine
A.) Antibiotic C.) Ephedrine
B.) Skeletal muscle relaxant D) Dopamine
C.) Antidepressant E.) Norepinephrine
D.) Anticonvulsant 102. Drugs with superior lipid solubility usually possess what
E.) Antipsychotic moiety?

A.) Oxygen
96. Insulin Receptors are classified as _______ B.) Nitrogen
C.) Chlorine
A.) Ion gated channel receptors D.) Sulfur
B.) Tyrosine kinase receptors E.) Fluorine
C.) G- protein coupled receptors
D.) Gene transcription linked receptor For numbers 103-107, Refer to the synthesis of Aspirin below
E.) Nuclear receptor
103. The compound that reacts to salicylic acid to make aspirin is
97. The efficacy of salicylic acid as well as its solubility in water an example of a/an______
as compared to p-hydroxybenzoic acid is greatly affected by
what phenomenon? A.) Alcohol
B.) Ketone
A.) Dipole movement C. Ether
B.) Common ion effect D.) Acid anhydride
C.) Hydrophobic interactions E.) Ester
D.) Hydrogen bonding
E.) Electrostatic forces 104. The major product (Aspirin) ia prone to hydrolysis, which of
the following is/are the product/s of its hydrolysis
98. The inhibition of the CYP 450 dependent lanosterol 14-alpha
demethylase is the main mechanism of action of? A.) Carboxylic acid
B.) Alcohol
A.) Ketoconazole C.) Ester
B.) Amphotericin B D. Both A and B
C.) Azelaic acid E. Both A and C
D.) Griseofulvin
E.) Nystatin 105. When aspirin has been hydrolyzed, one of its products
produces a keratolytic property, what is that product?
[Link] of aminobenzene will likely proceed to what position?
A.) Salicylic acid
A.) Ortho only B.) Undecylenic acid
B.) Ortho and Meta C.) Ester
C.) Meta and Para D. Methyl salicylate
D.) Para only E.)Alcohol
E.) Ortho and Para
106. What is the functional group of the major product has been
100. An aliphatic phenothiazine derivative formed?

A.) Chlorpromazine A.) Ether

B.) Thiorizadine B.) Alcohol
C.) Fluphenazine C.) Phenolic
D.) Perphenazine D.) Carboxylic acid
E.) Clozapine E.) Ester
 E.) Mannitol

113. This is a butyrophenone derived antipsychotic agent that is

frequently used for Tourette's syndrome

107. What is the color of the product when aspirin is treated with A.) Clozaril
Ferric Chloride? B.) Haldol
C.) Thorazine
A.) Blue D.) Daxolin
B.) Violet E.) Zoloft
C.) Yellow
D.) Red [Link] compound is the basis of the synthesis of thiazide
E.) Colorless diuretics by treating with acylating agents

108. Which of the following compounds can be used to A.) Acetazolamide

synthesize secondary alcohols? B.) Dichlorphenamide
C.) Chloraminophenamide
A.) Formaldehyde D.) Methazolamide
B.) Ethanoic acid E.) Indapamide
C.) Propanone
D.) Ethyl ethanoate 115. A non-prodrug ACE inhibitor
E.) Tert-butylbromide
A.) Quinapril
109. The following drugs undergo acetylation reaction upon B.) Captopril
metabolism except C.) Fosinopril
D.) Enalapril
A.) Hydralazine E.) Imidapril
B.) Ethanol
C.) Isoniazid For numbers 116-119, Refer to the structure of Azithromycin
D.) Procainamide
E.) Sulfanilamide 116. Compound such as Azithromycin possess the following
characteristics, except
110. Mercury exhibits is antimicrobial action by
A.) Large lactone ring
A.) Hydrolysis and protein denaturation B.) Ketone Group
B.) Oxidation of sulfhydryl group C.) Ether group
C.) Disruption of cytoplasmic membrane D.) Alkyl group
D.) Inhibitio of protein synthesis E.) Glycosidically linked sugar
E.) Protein denaturation inactivation of the bacterial enzyme
117. This class of antibiotic exerts its action by ________
111. Which of the following antibiotics is derived from
Streptomyces orientalis? A.) Binding to the 50s ribosomal subunit of bacteria
A.) Nystatin B.) Inhibition of cell wall cross linking
B.) Bacitracin C.) Inhibition of bacterial transpeptidation
C.) Vancomycin D.) Binding to the 30s ribosomal subunit of bacteria
D.) Amphotericin B E.) Inhibition of Nucleic acid synthesis
E.) Amikacin

112. Diuretic that acts on the thick ascending limb (TAL)

A.) Indapamide
B.) Furosemide
C.) Acetazolamide
D.) Amiloride
[Link] preparation of Azithromycin is done by ______ of its
analog. A.) Fentanyl
B.) Morphine
A.) Acetylation C.) Meperidine
B.) Oxidation D.) Codeine
C.) N-methylation E.) Naloxone
D.) Reduction
E.) Cross linking 125. Cyclophosphamide belongs to what class of
chemotherapeutic agents?
119. The presence of a tertiary amine group in the compounds
provides the following characteristics of A.) Antimetabolites
B.) Antibiotics
A.) Superior lipid solubility C.) Alkylating agents
B.) Increasing in plasma concentration D.) Microtubule synthesis inhibitors
C.) Acid - labile property E.) None of the above
D.) Stability to acid - catalyzed degradation
E.) Decreasing in plasma concentration 126. The amino acid precursor of catecholamines

120. Theophylline is also known as ____ A.) Tryptophan

B.) Threonine
A.) 5,7- Dimethylxanthine C.) Histidine
B.) 1,7- Dimethylxanthine D.) Tyrosine
C.) 3,7- Dimethylxanthine E.) Arginine
D.) 1,3- Dimethylxanthine
E.) 2,7- Dimethylxanthine 127. A nucleophile is a species that is rich in

For numbers 121-123, Refer to the structure below A.) Protons

B.) Neutrons
121. What functional group is attached to the primary amine C.) Radical
moiety? D.) Double bonds
E.) Electrons
A.) Carboxyl
B.) Acetyl 128. These are functional macromolecules that undergo structural
C.) Benzyl conformation when a substrate binds to it.
D.) Carbonyl
E.) Methyl A.) Receptors
B.) Enzymes
122. The main group of this compound C.) Ion channel
D.) Ligands
A.) Phenolic E.) Apienzymes
B.) Benzoic
C.) Amino 129. A drug with a pKa of 4.76 is likely to be excreted in what
D.) Amide medium?
E.) Hydroxyl
A.) Acidic
123. The compound possess only minimal ________ property. B.) Basic
C.) Neutral
A.) Analgesic D.) All of the above
B.) Anti-inflammatory E.) None of the above
C.) Anti-asthma
D.)Antipyretic
E.) Anti-platelet 130. The bond that connects the moieties of prilocaine is/ an

124. The prototype narcotic analgesic A.) Ester

B.) Amide C.) Levo isomer
C.) Carbonyl D.) Z- isomer
D.) Ether E.) E-isomer
E.) Amine
136. This product of arachidonic acid pathway is a potent platelet
For numbers 131-135, Refer to the structure of Adrenalin aggregator

A.) PGE
131. The drug is derivative of ________ B.) LTC4
C.) HETE
A.) Phenol D.) TXA2
B.) Resorcinol E.) PGF
C.) Benzene
D.) Catechol 137. A compound with a molecular formula of C2H6O is most like
E.) Hydroquinone to be a/a ______

132. The parent compound is highly susceptible to what type of A.) Alcohol
metabolic reaction? B.) Ether
C.) Ketone
A.) Reduction D.) Both B and C
B.) Methylation E.) Both A and B
C.) Hydrolysis
D.) Oxidation 138. Sulbactam is usually combined with what antibiotic?
E.) Glycine conjugation
A.) Amoxicillin
133. The compound is an endogenous substance in the body that B.) Methoxypenicillin
functions as C.) Piperacillin
D.) Benzylpenicillin
A.) Neurotransmitters E.) Ampicillin
B.) Enzyme
C.) Substrate 139. Addition of alcohol to an alkene yields what product?
D.) Ligand
E.) Hormone A.) Carboxylic acid
B.) Ether
134. The compound is used to manage _______ C.) Alkane
D.) Ester
A.) Tachycardia E.) Ketone
B.) Shock
C.) Pain 140. Orthohydroxybenzoic acid is _____
D.) Stroke
E.) Coagulation A.) Carboxylic acid
B.)Oxalic acid
C.) Citric acid
D.) Salicylic acid
E.) Tartaric acid

For numbers 141-145, Refer to the structure of Indocin

141. What is the most common adverse effect of this drug?

135. What configuration of this compound possess a biological
activity? A.) Optic neuritis
B.) Gastrointestinal irritation
A.) S-isomer C.) Tachycardia
B.) R-isomer D.) Adrenal insufficiency
E.) Hypoglycemia

142. In what enzyme does this drug acts? A.) Cell wall synthesis inhibition
B.) Inhibition of the 30s ribosomal subunit
A.) COX C.) Cell membrane synthesis inhibition
B.) COMT D.) Inhibition of the 50s ribosomal subunit
C.) LOX E.) DNA synthesis Inhibition
D.) PLA
E.) MAO 149. Which of the drugs below exhibit auto-oxidation?

143. This drug can be used to treat patients with A.) Carbamazepine
B.) Sotalol
A.) Acromegaly C.) Isoniazid
B.) Patent ductus arteriosus D.) Epinephrine
C.) Coagulation disorder E.) Metformin
D.) Renal failure
E.) Asthma 150. A rare spiro chemical structure is observed in what antifungal
drug?
144. This drug may likely bind to what protein?
A.) Amphothericin B
A.) Albumin B.) Griseofulvin
B.) Globulin C.) Tolnaftate
C.) Alpha glycoprotein D.) Miconazole
D.) All of the above E.) Azelaic acid
E.) None of the above
151. Typical reaction of alkanes
145. The drug is a derivative of what compound?
A.) Nucleophilic addition
A.) Imidazole B.) Radical halogenation
B.) Xanthine C.) Elimination
C.) Furan D.) Electrophilic substitution
D.) Piperidine E.) Cyclization
E.) Indole
152. Secondary alcohols are oxidized into
146. Name of this compound
A.) Aldehyde
A.) Pyran B.) Esters
B.) Indole C.) Ketone
C.) Pyrrole D.) Carboxylic acids
D.) Imidazole E.) Ethers
E.) Furan

153. Which of the following diuretic inhibits an enzyme?

A.) Furosemide
147. This is the common name of p- hydroxy phenol B.) Thiazides
C.) Mannitol
A.) Catechol D.) Indapamide
B.) Resorcinol E.) Acetazolamide
C.) Quinone
D.) Hydroquinone 154. Acetylene has a geometrical configuration of
E.) Benzoic acid
A.) Planar
148. Polyene anti-infectives exert their mechanism of action by B.) Octagonal
C.) Rhombic D.) Amide
D.) Tetrahedral E.) Alcohol
E.) Cubic
161. Predict the product of the reaction
155. A uricosuric agent used to prevent the rapid excretion of
penicillin A.) Ar-OCl
B.) Ar-OR
A.) Sulindac C.) Ar-Cl
B.) Probenecid D.) Ar-CO
C.) Colchicine E.) Ar- COR
D.) Felbamate
E.) Lamotrigine 162. Corticosteroids are protent Anti-inflammatory drugs because
they inhibit which enzyme?
156. Friedle - Crafts alkylation of benzene requires this catalyst
A.) Lipoxygenase
A.) Bronsted base B.) Phospholipase
B.) Lewis acid C.) Transferase
C.) Bronsted acid D.) Thromboxane
D.) Arrhenius acid E.) Cyclooxygenase
E.) Lewis base
163. G- protein coupled receptors are activated via these
157. This is the property of carbon atom where it form bonds secondary messengers, except
with other carbon atoms
A.) cAMP
A.) Covalent bonding B.) IP3
B.) Catenation C.) DAG
C.) Non- polar bonding D.) cGMP
D.) Electronegativity E.) NO
E.) Ionic bonding
164. An enol is not a stable compound because it undergoes
158. Geometry of an sp3 hybridized orbital
A.) Nucleophilic attack
A.) Rhombic B.) Hydrophobic interactions
B.) Planar C.) Hydrogen shift
C.) Tetrahedral D.) Tautomerization
D.) Cubic E.) Hydrophilic attack
E.) Octagonal
165. Which is the most stable conformation of cyclohexane
159. It is the strain occured when electrons in a C-H bond will
repel the electrons in another C-H bond if the bonds get too close A.) Chair
to each other B.) Boat
C.) Staggered
A.) Angular strain D.) Eclipsed
B.) Torsional strain E.) Planar
C.) Equatorial strain
D.) Steric strain 166. It is the strain put on a molecule when atoms
E.) Axial strain Or groups are too close to one another.

160. Lindlar's catalyst is employed to produce a/an ______ A.) Angular Strain
from the reaction of H2 to an alkyne B.) Torsional Srain
C.) Equatorial Strain
A.) Ketone D.) Steric Strain
B.) Alkene E.) Axial Strain
C.) Amine
167. An aliphatic phenothiazine derivative C.) sp2
D.) Octagonal
3
A.) Chlorpromazine E.) sp
B.) Fluphenazine
C.) Perphenazine 174. Reactions of terminal alkynes follow the ____ when it is
D.) Thioridazine treated with excess HCL/HBr
E.) Thiothixene
A.) Le Chatelier’s Principle
168. What is the prominent adverse effect of aminogycosides? B.) Markovnikov’s rule
C.) Heck Reaction
A.) Hepatotoxicity D.) Hund’s Rule
B.) Cardiotoxicity E.) Pauli’s Principle
C.) Neurotoxicity
D.) Nephrotoxicity 175. Addition of water to an alkyne leads to the formation of
E.) Dermal toxicity
A.) Alcohol
169. A theory that states that the effectiveness of the drug last B.) Carboxylic acid
as long as the receptors are occupied C.) Ketone
D.) Aldehyde
A.) Hypothesis of Paton E.) Ester
B.) Lock and Key theory
C.) Hypothesis of Clark 176. Primary reaction of alkyl halides
D.) Induced fit theory
E.) Hypothesis of Ariens & Stephenson A.) Nucleophilic addition
B.) Radical halogenations
170. Bacitracin is not usually given parenterally because of its C.) Elimination
D.) Electrophilic substitution
A.) Insolubility E.) Nucleophilic substitution
B.) Nephrotoxicity
C.) Pain on the administration site 177. SN2 reaction is primarily observed in
D.) Lack of stability
E.) Lack of potency A.) Secondary amines
171. Which of the following medications would represents arthritis B.) Tertiary alkyl
therapy that is least likely to cause gastric ulceration? C.) Primary alkyl halides
D.) Primary alcohols
A.) Sulindac E.) All of the above
B.) Rofecoxib
C.) Tolmetin
D.) Piroxicam 178. Which of the following is not a characteristic of an ideal
E.) Phenylbutazone antiseptic agent?

172. Methylbenzene is also known as A.) Low toxicity

B.) High surface tension
A.) Anisole C.) Non-allergenic
B.) Toluene D.) Low surface tension
C.) Aniline E.)Sustained and rapid lethal action against microorganisms
D.) Xylene
E.) Anethole 179. Which organism is the standard for determining the efficacy
of alcohols as antiseptic?
173. Alkyl substituent that are bounded to the ____ carbons of
an alkene have a stabilizing effect on the alkene. A.) Streptococcus agalactiae
B.) Staphylococcus aureus
A.) sp C.) Salmonella Typhi
B.) Tetrahedral D.) Hemophilus influenza
 E.) Klebsiella pneumonia D.) Cresol
E.) Alcohol
180. This agent is prepared by sulfuric acid catalyzed hydration of
propene 186. Organism used as standard for the efficacy of phenol and its
derivatives
A.) Methoxypropane
B.) N-Propanol A.) Streptococcus agalactiae
C.) Isopropyl alcohol B.) Staphylococcus aureus
D.) Propylene C.) Salmonella typhi
E.) Propanoic acid D.) Hemophilus influenzae
E.) Klebsiella pneumonia
181. Chlorocresol is primarily used as
187. Used to treat diaper rash in infants caused by Candida albbicans
A.) Preservative
B.) Alkylating agent A.) Methylbenzethonium chloride
C.) Astringent B.) Thimerosal
D.) Sterilant C.) Ethylene oxide
E.) Fungicidal D.) Chlorhexedine
E.) Methylene blue
182. In the structure of cephalosporins, the beta lactam ring
should have the ____ configuration that is essential for its activity

A.) Trans
B.) E
C.) Levo 188. Which of the following is used as a keratolytic agent?
D.) Dextro A.) Thymol
E.) Cis B.) Resorcinol
183. Which of the following characteristics of the bicyclic ring system C.) Eugenol
of penicillins is true? D.) Chlorocresol
E.)Hexachlorphene
A.) Strain is essential for greater activity
B.) Substitution of an alkyl group to the 189.) Which of the following is the salt of Penicillin G?
Hydrogen moiety in the beta lactam ring confers
Greater efficacy A.) Potassium
C.) The trans streochemistry in the beta lactam B.) Calcium
Ring ring confers greater efficacy C.) Sodium
D.) Activity increases when the carboxylic acid D.) All of these
Group is modified into an ester E.) None of these
E.) Sulfur is an essential atom in the bicycling
Ring system 190. Saponification is the alkali hydrolysis of
184. Which of the following is true for hydrogen peroxide
A.) R-O-R
A.) Active against aerobic microorganism B.)R-COOR
B.) Good only as topical agent C.) R-COOH
C.) Inactive for anaerobic microorganism D.) R-OH
D.) Superior tissue penetrability E.) Ar-OH
E.) Use as a preservative for heat sensitive chemicals
191. Aminobenzene is also known as
185. Which of the following exerts their action by distortion of cells
and eventually causing lysis? A.) Anisole
B.) Toluene
A.) Benzalkonium chloride C.) Aniline
B.) Phenol D.) Xylene
C.) Iodine E.) Anethole
192. This is a derivative of two carboxylic acids, in which the 198. DNA alkylating agents binds to its target by means of what bond?
compound is formed by the removal of one molecule of water in two
RCOOH A.) Hydrophobic
B.) Ionic
A.) Acyl halide C.) Covalent
B.) Esters D.) Electrostatic
C.) Alkyl halide E.) Hydrogen
D.) Acid anhydride
E.) Ethers 199. Theobromine is also known as

193. Saquinavir belongs to what group of HIV drugs? A.) 5, 7 –Dimethylxanthine

B.) 1, 7 - Dimethylxanthine
A.) Nucleosides Reverse Transcriptase Inhibitor C.) 3, 7- Dimethylxanthine
B.) Protease Inhibitor D.) 1, 3 – Dimethylxanthine
C.) RNA synthesis inhibitor E.) 2, 7- Dimethylxanthine
D.)Fusion inhibitor
E.) Non-Nucleoside Reverse Transcriptase Inhibitor

200. The following are the effects of protein binding, except

194. Dehydration of secondary alcohols yield A.) Prevent rapid excretion of the drug
B.) Limits the amount available for the metabolism
A.) Alkyne C.) Decreases free drug molecules
B.) Alkane D.) Decreases half-life of drugs
C.) Ketone E.) None of the above
D.) Akene
E.) Alkyl halide 201. This agent is used to chelate copper in which an excess amount
causes Wilsson’s disease
195. Thimerosal is a preservative that contains
A.) Hg A.) Deferoxamine
B.) Fe B.) EDTA
C.) Co C.) Penicillamine
D.) Ni D.)BAL
E.) Cu E.)Dimercaprol

196. Imidazole nucleus is primarily found in what type of anti-infective 202. A paraben used to preserve the drug from molds
agents? A.) Mehylparaben
B.) Ethylparaben
A.) Antiseptics C.) Propylparaben
B.) Antiviral D.) Butylparaben
C.) Disinfectants E.) N-butylparaben
D.) Antimycobacterials
E.) Antifungal 203. Reduction of Aldehydes yield

197. The receptor of steroidal hormones are primarily found in A.) Carboxylic acid
the____. B.) Primary alcohols
C.) Ethers
A.) Cell membrane D.) Ketones
B.) Nucleus E.) Secondary alcohols
C.) Ribosomes
D.) Cytoplasm 204. Alkenes have a general formula of
E.) Cell wall
A.) CnH2n+1 210. The heterocyclic ring in its structure is
B.) CnH2n+2
C.) CnH2n A.) Indole
D.) CnHn B.) Furan
E.) CnH2n-2 C.) Pyran
D.)Pyridine
205. In the presence of a full agonists, a partial agonist becomes E.) Imidazole
_____
211. This drug has a weak antiandrogenic effect, therefore, one of its
A.) Remained as partial agonist adverse effects is :
B.) Antagonist
C.) Both agonist and antagonist A.) Gynecomastia
D.) Inverse agonist B.) Hirsutism
E.) Full agonist C.) Adrenaline crisis
D.) Flushing
E.) Cushing syndrome

212. This drug antagonize what receptor?

206. These are substances that donate an electron pair
A.) Alpha 1
A.) Lewis acid B.) Dopamine
B.) Bronsted base C.) Muscarinic 3
C.) Lewis base D.) Histamine 1
D.) Arrhenius base E.) Beta 1
E.) Bronsted acid
213. The following molecules readily penetrate a variety of cells and
207. The following agents are used to treat hyperacidity and GI tissues, Except
ulceration, except
A.) Hydrophobic
A.) Cytotek B.) Non - ionized
B.) Ranitidine C.) Hydrophilic
C.) Omeprazole D.) Lipid soluble
D.) Aripiprazole E.) Non polar
E.) Maalox
214. Active site directed irreversible inhibition is exhibited in what type
208. The amino acid precursor of serotonin of bond

A.) Threonine A.) Electrostatic

B.) Arginine B.) Van der Waals
C.) Tyrosine C.) Hydrogen bonding
D.) Tryptophan D.) Ionic
E.) Histidine E.) Covalent

209. Dynacin® binds to the _____ ribsomal subunit For numbers 215-217, Refer to the structure of Aldomet®

A.) 20s 215. This drug is an analog of what neurotransmitter?

B.) 30s
C.) 60s A.) Norepinephrine
D.) 40s B.) Serotonin
E.) 50s C.) Glutamate
D.) GABA
E.) Histamine
For numbers 210-212, Refer to the structure of Tagamet®
216. This drug exerts effect as a _______
 A.) Benzodiazepine
A.) Hydroxylase inhibitor B.) Imidazole
B.) Decarboxylase inhibitor C.) Barbiturates
C.) Transferase inhibitor D.) Indole
D.) Carboxylase inhibitor E.) Pyrrole
E.) Protease inhibitor
223. Gq receptors stimulates________ that leads to increase in
217. This is primarily indicated for ______ the intracellular calcium level

A.) Cardiac failure A.) Phospholipase

B.) Hypertension B.) Lipoxygenase
C.) Muscle pain C.) DOPA Decarboxylase
D.) Aldosteronism D.) Carboxylase
E.) Cushing syndrome E.) Cyclooxygenase

218. A lipoxygenase enzyme inhibitor 224. Cholestyramine confers what type of antagonism?

A.) Montelukast A.) Pharmacodynamic

B.) Zileuton B.) Chemical
C.) Cromolyn C.) Physical
D.) Zafirlukast D.) Pharmacokinetic
E.) Nedocromyl E.) Physiological

For numbers 219-222, Refer to the structure of Luminal® 225. Dehydrated alcohol is prepared by the azeotropic distillation using
what solvent?

219. The compound may likely increase the concentration of ______ A.) Toluene
in the cell B.) Pyridine
C.) Chloroform
A.) Sodium D.) Benzene
B.) Calcium E.) Hexane
C.) Magnesium
D.) Potassium 226. Which of the following is the most effective?
E.) Chloride
A.) Tert-butyl alcohol
220. The compound has an affinity to what receptor? B.) N-decanol
C.) 3-hexanol
A.) Glutamate D.) Ethanol
B.) Serotonin E.) 4-pentanol
C.) GABA
D.) Glycine 227. Used in combination with camphor in liquid petrolatum
E.) Histamine
A.) P-Chlorophenol
221. The compound is used to treat what condition? B.) Eugenol
C.) Chlorhexidine
A.) Asthma D.) Cresol
B.) Fungal infection E.) Thymol
C.) Depression
D.) Convulsion 228. Which of the following substituents increase the activity of
E.) Hypertension phenol?

222. This compound resembles a/an A.) Chlorine

B.) Sulfur
C.) Phosphorus 235. The first step that determines the onset of action, rate of
D.) Oxygen absorption and bioavailability
E.) Nitrogen
A.) Liberation
229. It induces cell proliferation (epithelial) leading to sloughing and B.) Metabolism
repair C.) Elimination
D.) Absorption
A.) Carbamide peroxide E.) Distribution
B.) Hexylresorcinol
C.) Cetylpyridium chloride
D.)Chlorhexidine 236. Nevirapine is known to cause _______ for HIV patients with
E.) Benzoyl peroxide low CD4 count

A.) Renal failure

230. Which of the following dyes is used as vaginal suppository? B.) Rash
C.) Mouth sore
A.) Methylene blue D.) Vertigo
B.) Malachite green E.) Cardiomegaly
C.) Gentian violet
D.) Carbolfuchsin 237. Insulin preparation that is made of 70% crystalline and 30%
E.) Bromocresol amorphous form

231. Which of the following penicillin is prone to renal tubular secretion? A.) Humalin
B.) Insulin NPH
A.) Methicillin C.) Short acting insulin
B.) Pen G D.) Insulin glargine
C.) Carbenicillin E.) Insulin Lispro
D.) Cloxacillin
E.) Ampicillin 238. Type of antagonism that forms a chelate/ complex

232. The structure contains the salt of what amino acid? A.) Physical
B.) Pharmacokinetic
A.) Alanine C.) Physiological
B.) Valine D.) Chemical
C.) Lysine E.) Pharmacodynamic
D.) Isoleucine
E.) Arginine 239. Secondary messenger produced when adenyl cyclase is activated

233. The first type of drug released to treat HIV infection A.) IP3
B.) DAG
A.) Nucleoside Reverse Transcriptase Inhibitor C.) cAMP
B.) Protease Inhibitor D.) Both A and B
C.) RNA synthesis inhibitor E.) Both B and C
D.) Fusion Inhibitor
E.) Non-Nucleoside Reverse Transcriptase Inhibitor For numbers 240-241, Refer to the reaction :

234. The ability of a substance to exist in different crystalline form 240. The metabolic pathway is an example of

A.) Isomerism A.) Reductive elimination

B.) Lattice B.) Oxidative deamination
C.) Crystallization C.) Reductive deamination
D.) Polymorphism D.) Hydrolysis
E.) Ampotherism E.) Oxidative dealkylation
241. This pathway is true for what kind of compounds?

A.) Endogenous radicals

B.) Endogenous amides
C.) Endogenous amino acids
D.) Endogenous amines
E.) None of these 246. Which of the following compounds is considered as a
chromophore?
242. Which of the following is/are true regarding the phase I drug
metabolism? A.) Nitro
B.) Butyl
I. Also known as conjugation reaction C.) R-O-R
II. Includes oxidation, reduction and hydrolysis D.) R-OH
III. Generally tends to provide a functional group or "handle" to the E.) Cyclohexane
molecule
247. Which of the following catalyst is required for the synthesis of
A.) I only an ester
B.) I, II, III
C.) II only A.) HBr
D.) II and III B.) CH3Cl
E.) I and III C.) NH4NO3
D.) H2SO4
243. Biogenic amines are inactivated primarily by E.) CCl4

A.) Oxidation 248. Which of the following form is the stable?

B.) Methylation
C.) GSH conjugation A.) Tertiary carbocation
D.) Sulfate conjugation B.) Primary carbanion
E.) Reduction C.) Primary carbocation
D.) Methyl radical
244. Which of fhe following is /are true regarding phase II drug E.) Secondary carbocation
metabolism?
249. Which of the following reagents can be used to solubilize phenol
I. Allows the attachment of small, polar and ionizable endogenous in water?
compounds
II. Allows the termination or attenuated of a biologic activity A.) HCl
III. Serves to protect the body against chemically reactive compounds B.) NaOH
or metabolites C.) CH2Cl2
D.) HBr
A.) II and III E.) NH2CONH2
B.) I, II, III
C.) I only 250. Ethanol is identified by this reagent in its confirmatory test
D.) I and II
E.) III only A.) Ammonium cyanide
B.) Phosphomolybdic acid
245. Which of the following can be used to synthesize methyl orange? C.) Aluminum chloride
D.) Potassium perchlorate
A.) Methyl alcohol E.) Sodium nitroprusside
B.) Toluene
C.) Benzyl chloride 251. Violet color result with ferric chloride is commonly observed in
D.) Sulfanilic acid
E.) Ammonium nitrite A.) Aspirin
B.) Phenol
C.) Propylamide
D.) Benzene
E.) Acetic acid 258. The spectrum of activity of penicillin is governed by what
functional group?
252. Benzoic acid can be obtained from toluene by means of what
process? A.) Beta lactam ring
B.) Carbonyl group
A.) Reduction C.) Acyl amine group
B.) Substitution D.) Carboxylic acid group
C.) Oxidation E.) Thiazolidine ring
D.) Elimination
E.) Conjugation For numbers 259-263, Refer to the structure of this beta lactam
antibiotic :
253. Which of the following compounds inhibits squalene oxidase?
259. The functional group attached to the acyl amino group is called
A.) Tolnaftate a/an
B.) Undecylanic acid
C.) Natamycin A.) Benzyl
D.) Ketoconazole B.) Isoxazoyl
E.) Benzoic acid C.) Phenoxymethyl
D.) Phenyl
254. Inhibition of the production of folic acid is the mechanism of E.) Methoxyphenyl
action of
260. What is the role of chloride atoms in the structure?
A.) Griseofulvin
B.) Sulfamethoxazole A.) Increase the susceptibility to penicillinase
C.) Norfloxacin B.) Increase the plasma concentration
D.) Nystatin C.) Increase in parenteral absorption
E.) Nalidixic acid D.) Acid resistance property
E.) Increase spectrum of activity
255. Polyene antifungals bind to ______ to promote ion leakage
resulting to fungal death 261. Halogen substituents are best placed in what position?

A.) Microtubules A.) Ortho

B.) DNA B.) Meta
C.) Cell wall C.) Para
D.) Ribosomes D.) All of the above
E.) Ergosterol E.) None of the above

256. The second synthetic analog of Benzylpenicillin 262. Adding more than 1 chloride atom in the structure confers what
modification on the pharmacokinetic profile of the drug?
A.) Phenoxymethylpenicillin
B.) Methicillin A.) Liberation
C.) Oxacillin B.) Absorption
D.) Ampicillin C.) Excretion
E.) Cloxacillin D.) Distribution
E.) Metabolism
257. The subtype of the CYP 450 enzyme system responsible for
genetic polymorphism

A.) CYP 1A2

B) CYP 2A9
C.)CYP 2D6
D.) CYP 1A9
E.)CYP 3A4 263. This antibiotic is primarily indicated for what type of infection?
 A.) Hexetidine
A.) Enterobacter B.) Hexachlorophene
B.) Streptococci C.) Chlorocresol
C.) Pseudomonas D.) Chlorhexidine
D.) Klebaiella E.) Chlorophenol
E.) Staphylococci
270. Second generation cephalosporin that can cross the blood brain
264. Functional group of the beta - lactam ring barrier

A.) Ether A.) Cefamandole

B.) Ketone B.) Cefprozil
C.) Amide C.) Cefuroxime
D.) Amine D.) Cefaclor
E.) Carbonyl E.) Loracarbef

For numbers 265-269, Refer to the structure of a phenol derivative 271. Compounds that will kill or inhibit the growth of, in a living tissue
compound
A.) Disinfectant
265. This compound is insoluble in what medium? B.) Antibiotic
C.) Antiseptic
A.) Water D.) Preservativs
B.) Alcohol E.) Sterilant
C.) Ether
D.) Carbon tetrachloride 272. It is the characteristics of a substance that gives its ability to
E.) Benzene spread into wounds.

266. This compound is active against _______ organism A.) High viscosity
B.) Low zeta potential
A.) Gram positive C.) High partition coefficient
B.) Acid fast D.) Low surface tension
C.) Aerobic E.) High pH
D.) Facultative anaerobe
E.) Gram negative 273. Tigemonam is primarily administered in what route?

267. This compound has a greater potency of action due to the A.) IV
presence of what group? B.) Subq
C.) Topical
A.) Alkyl D.) IM
B.) Halogen E.) PO
C.) Phenolic
D.) Biphenyl 274. Redman syndrome is seen in
E.) Hydroxyl
A.) Telavancin
268. This preparation is to be delivered in what route? B.) Chloramphenicol
C.) Imipenem
A.) Intramuscular D.) Teicoplanin
B.) Intradermal E.) Vancomycin
C.) Topical
D.) Subcutaneous
E.) Intravenous

275. Preservative in BCG Vaccine

269. The compound is commonly known as
A.) Nitromersol
B.) Thimerosal E.) Decrease in protein binding
C.) Benzalkonium chloride
D.) Methylparaben 282. Aztreonam can elevate this enzyme
E.) Sodium benzoate
A.) Creatinine kinase
276. Metabolism of alcohol is a series of B.) Alanine aminotransferase
C.) Beta amylase
A.) Reduction D.) Angiotensin I
B.) Methyl transfer E.) Pyruvate kinase
C.) Glycine conjugation
D.) GSH conjugation 283. This group attached to the naphthalene group of nafcillin confers
E.) Oxidation beta lactamase resistance

277. Dye used to treat the inflammation of the bladder A.) Dichlorobenzene
B.) Ethoxy
A.) Methylene blue C.) Benzyl
B.) Malachite green D.) Isoxazoyl
C.) Gentian violet E.) Phenyl
D.) Carbolfuchsin
E.) Bromocresol 284. Acylation of the amino group in the second ring of
aminoglycosides produces ______
For numbers 278-281,Refer to the general structure of cephalosporin
A.) Kanamycin
278. Which moiety in the structure binds to the PBP? B.) Streptomycin
C.) Neomycin
A.) Amide group D.) Gentamicin
B.) Carboxy group E.) Amikacin
C.) Dihydrothiazine group
D.) Carbonyl group 285. This is the target site of HIV
E.) Acyl amino
A.) CD8
279. The R3 substituent confers the following properties, except B.) CCR5
C.) CD4
A.) Salt form D.) CD32
B.) Drug interaction E.) CD28
C.) Protein binding
D.) Chemical stability 286. Antitubercular drug that is in combination with pyridoxine
E.) Pharmacological property
A.) Isoniazid
280. The R7 substituent is importantin _______ B.) Ethambutol
C.) Rifampicin
A.) Spectrum of activity D.) Pyrazinamide
B.) Classification of generation E.) Streptomycin
C.) Synthesis of a newer version
D.) All of these
E.) None of these 287. The chances of methemoglobinemia and haemolytic anemia are
higher when administering :

281. Substitution of a bulky group in the X substituent confers I. Acetaminophen

II. Phenacetin
A.) Acid labile property III. Acetanilide
B.) Increase in metabolism
C.) Decrease in GFR A.) I only
D.) Increase in gram negative activity B.) I and II only
C.) II and III only groups.
D.) I, II and III B.) The aromatic ring that is directly attached to the side - chain
E.) III only carbonyl and ortho and para positions should be substituted by
methoxy groups.
288. This agent is the least active among all fluoroquinolones C.) The aromatic ring that is directly attached to the side - chain
carbonyl and meta and para positions should be substituted by methoxy
A.) Norfloxacin groups.
B.) Levofloxacin D.) A methylene between the aromatic ring and carbonyl group of side
C.) Ofloxacin chain
D.) Ciprofloxacin E.) None of the above
E.) Gatifloxacin
294. Triethylenephosphoramide is an active metabolite of
289. Inhibits the enzyme which is responsible for the assembly of
matured viral particles A.) Procarbazine
B.) Camustine
A.) Didanosine C.) Thiotepa
B.) Zidovudine D.) Ifosfamide
C.) Indinavir E.) None of the above
D.) Abacavir
E.) Lamivudine 295. Which of the following preparations contains 2% iodine in sodium
iodide?
290. This antifungal drug is derived from Ricinus communis
A.) Iodine solution
A.) Undecylenic acid B.) Lugol's solution
B.) Ricinoleic acid C.) Povidone-iodine
C.) Salicylic acid D.) Iodine tincture
D.) Ricin E.) None of the above
E.) Propionic acid
296. Which of the following belongs to the class of echinocandins?
291. Which of the following is unstable in acidic condition?
A.) Caspofungin
A.) Ampicillin B.) Griseofulvin
B.) Methicillin C.) Naftiline
C.) Phenoxymethylpenicillin D.) Ampothericin B
D.) Nafcillin E.) Nystatin
E.) Carbenicillin

297. Concentration of dehydrated alcohol

A.) 95%
292. Carbamazepine undergoes what metabolic pathway? B.) 49%
C.) 99%
A.) Aromatic hydroxylation D.) 70%
B.) Olefinic oxidation E.) 10%
C.) Reductive elimination
D.) Oxidative N-dealkylation 298. An acy ureidopenicillin
E.) Desulfuration
A.) Piperacillin
293. To Prepare beta-lactamase resistant penicillin, one should use B.) Carbenicillin
C.) Methicillin
A.) The aromatic ring that is directly attached to the side-chain D.) Ticarcillin
carbonyl and both ortho positions should be substituted by methoxy E.) Cloxacillin
299. Chemically known as 5-methyl-3-phenyl-4-isoxazoyl penicillin

A.) Nafcillin
B.) Ticarcillin
C.) Oxacillin
D.) Methicillin
E.) Mezlocillin

300. Synthesis of Orange II Dihydrate is possible via

A.) Freidel-Crafts Acylation

B.) Diazotization
C.) Elimination
D.) Electrophilic aromatic substitution
E.) Nucleophilic addition