Anabolics and their effect on
Exercise performance
Presented to
Dr . Osama Khaled PT PhD
Exercise physiology PT5
Definition
Anabolic steroids, often referred to as anabolic-androgenic steroids (AAS), are
synthetic versions of testosterone, the male hormone, created to stimulate
muscle growth and improve athletic performance. Although these steroids
have valid medical applications for conditions such as muscle wasting and
hormonal imbalances, their use outside of a medical context, especially in
sports, poses considerable health risks.
Athletes, bodybuilders, and fitness enthusiasts frequently misuse these
substances to enhance muscle size and accelerate recovery from
rigorous exercise. However, such misuse can lead to serious health
issues, including heart problems, liver damage, psychological effects
like mood fluctuations and depression, and hormonal imbalances that
can result in infertility and unwanted breast development in men. While
anabolic steroids generally do not cause a euphoric effect, users may
develop a dependency and face withdrawal symptoms, including
depression, when discontinuing their use.
The difference between Anabolic and Catabolic
Anabolic processes Catabolic processes
involve the building up of break down complex molecules
complex molecules from simpler into simpler forms, releasing
ones, typically using energy. energy. These reactions provide
These processes are key to the fuel needed for cellular
growth, repair, and muscle activity, such as breaking down
building. For example, anabolic glucose during exercise
reactions include synthesizing
proteins from amino acids.
Differences in Exercise
Anabolic Exercise: This includes
short-duration, high-intensity
activities like weightlifting, sprinting,
and High-Intensity Interval Training
(HIIT). These exercises stimulate
muscle repair and growth by
creating micro-tears in muscle
fibers, which are rebuilt during
recovery using energy and
nutrients.
Differences in Exercise
Catabolic Exercise: Aerobic or
endurance activities such as
running, swimming, and cycling
fall into this category. They
involve sustained effort, breaking
down glycogen and fat to provide
energy during the activity.
Differences in Exercise
The combination of anabolic and
catabolic exercises is often
recommended for balanced fitness,
as anabolic workouts build muscle
while catabolic exercises improve
cardiovascular health and burn fat .
Effect of anabolic on exercise
Increased Muscle Mass: Anabolic steroids promote protein synthesis,
leading to increased muscle size and strength.
Enhanced Recovery:They can reduce recovery time after intense workouts,
allowing for more frequent training sessions.
Effect of anabolic on exercise
Improved Endurance : Some anabolic agents can enhance endurance by
increasing red blood cell production, which improves oxygen delivery to
muscles.
Fat Loss : Anabolic steroids can help in reducing body fat while preserving
lean muscle mass, contributing to a more defined physique.
Effect of anabolic on exercise
Psychological Effects :Users may experience increased aggression and
motivation, which can enhance performance during training.
Potential Side Effects : Long-term use can lead to serious health risks,
including cardiovascular issues, liver damage, hormonal imbalances, and
psychological effects like aggression and mood swings.
Effect of anabolic on exercise
Legal and Ethical Considerations :The use of anabolic steroids is banned in
most competitive sports, and their non-medical use is illegal in many
jurisdictions.
Contraindications
Anabolic steroids are prohibited for certain groups of
people due to health risks, ethical concerns, and legal
regulations. Those typically prohibited from using anabolic
steroids include:
1. Athletes : Many sports organizations, including the International Olympic
Committee and various professional sports leagues, ban the use of
anabolic steroids to ensure fair competition and to protect athletes’
health.
Contraindications
2. Minors : Individuals 3. Individuals with certain
under the age of 18 are medical conditions:
generally advised People with specific
against using anabolic health issues, such as
steroids due to the heart disease, liver
potential for serious disease, or hormone-
side effects and the related disorders, may be
impact on developing advised against steroid
use due to the associated
bodies.
risks.
Contraindications
4. Pregnant or 5. Individuals using
breastfeeding women: certain medications :
The use of anabolic Those taking medications
steroids can harm fetal that could interact
development or affect negatively with anabolic
nursing infants. steroids may be
prohibited from using
them.
Side effect
Anabolic-androgenic steroids (AAS) are synthetic derivatives of testosterone
widely used to enhance muscle mass, strength, and athletic performance.
However, their misuse poses significant health risks, including contraindications
and side effects that impact exercise performance.
1. Cardiovascular Risks: Prolonged use can lead to cardiomyopathy,
arrhythmias, hypertension, and atherosclerosis, which impair physical
endurance and increase the risk of life-threatening events during
exercise .
Side effect
2. Musculoskeletal Effects: While AAS may temporarily enhance muscle strength,
they can weaken tendons and increase the risk of ruptures. Additionally, in
adolescents, premature epiphyseal closure may stunt growth .
3. Reproductive and Hormonal Issues: AAS suppress natural testosterone
production, causing hypogonadism and infertility in males. Women may experience
virilization and menstrual irregularities, some of which are irreversible .
Side effect
4. Psychological Effects: Abuse is linked to mood swings, aggression, and
dependency, which can hinder consistent training and recovery .
5. Immune and Kidney Function: High doses can suppress immune function and
harm kidney structures, especially under dehydrated or high-stress conditions
during exercise .
Examples of Anabolics and Their Effects on Exercise Performance
[Link] [Link] [Link] Growth Hormone
• Effect: Enhances muscle • Effect: Promotes muscle
mass, strength, and • Effect: Increases fat growth, accelerates
recovery by increasing metabolism and lean recovery, and reduces
protein synthesis. muscle development. body fat.
• Risks: Hormonal • Risks: Heart palpitations, • Risks: Joint pain, insulin
imbalances, cardiovascular muscle cramps, and high resistance, and abnormal
disease, and liver damage. blood pressure. tissue growth.
Examples of some exercises that athletes can do
after taking Anabolic
1. Strength Training:
- squats: To build thigh and glute muscles.
- Deadlifts: To strengthen the lower back and legs.
- Pull-Ups: To strengthen back and arm muscles.
- Shoulder Press: To strengthen the shoulders.
Examples of some exercises that athletes can do
after taking Anabolic
2. Weight Training:
- Dumbbell Training:Such as bicep curls and tricep extensions.
- Bench Press: To strengthen chest muscles.
Examples of some exercises that athletes can do
after taking Anabolic
3. Endurance Training:
- Running: To improve cardiovascular fitness and endurance.
- cycling :To enhance endurance and overall fitness.
Examples of some exercises that athletes can do
after taking Anabolic
4. Functional Strength Training:
- Full-Body Workouts: Such as kettlebell exercises and CrossFit.
- Jump Squats: To increase strength and endurance.
Examples of some exercises that athletes can do
after taking Anabolic
5. Flexibility Training:
- Stretching: To improve flexibility and recovery.
These exercises help athletes maximize the effects of steroids,
leading to improved performance, increased strength, and
overall fitness.
Signs and effect of Anabolic Steroid in Women
There are significant negative physical and psychologic effects of anabolic
steroid use. Anabolic steroid use in women can cause significant changes .
such as :
Acne
Hirsutism
Deepening of the voice
Male pattern balding
Breast atrophy
Signs and effect of Anabolic Steroid in Women
There are significant negative physical and psychologic effects of anabolic
steroid use. Anabolic steroid use in women can cause significant changes .
such as :
Irregular menstrual cycles
Infertility
Significant muscle growth
Depression
Mood instability.
Biomechanics changes (tendon injuries)
Thank you
Students Names :
Aryam Mohammed Al-sharif 4455559
Aram khalid 4450863
Amaal Menwer Alharbi 4456150
Horya Salah Al-motabaqani 4454414
Reham hlil 4456942
Remas Sameer Abdulshakour 4453458
Maha shalah Al-harbi 4454110
Wasan Fares Al-Oufie 4456308
Reference :
1 - Buttner A, Thieme D. Side effects of anabolic androgenic steroids: pathological findings and structure-activity
relationships. Handb Exp Pharmacol. 2010;195:459–484.
2 - Casavant MJ, Blake K, Griffith J, Yates A, Copley LM. Consequences of use of anabolic androgenic steroids. Pediatr Clin
North Am. 2007;54(4):677–690.
3 - Maravelias C, Dona A, Stefanidou M, Spiliopoulou C. Adverse 145.
effects of anabolic steroids in athletes: a constant threat. Toxicol
Lett. 2005;158(3):167–175.
4 - Kicman, A. T. (2008). Pharmacology of anabolic steroids. British Journal of Pharmacology, 154(3), 502–521.
[Link]
5 - Russell, James B., and Gregory M. Cook. "Energetics of bacterial growth: balance of anabolic and catabolic reactions."
Microbiological reviews 59.1 (1995): 48-62.
6 -Russell, J. B., & Cook, G. M.-
(1995). Energetics of bacterial growth: balance of anabolic and catabolic reactions. Microbiological reviews, 59(1), 48-62.
7 - RUSSELL, James B.; COOK-, Gregory M. Energetics of bacterial growth: balance of anabolic and catabolic reactions.
Microbiological reviews, 1995, 59.1: 48-62.
8 - SportsRec. (n.d.). Anabolic Exercise vs. Catabolic Exercise. [online] Available at: [Link]
[Link] [Accessed Date].
Reference :
9 - Verywell Health. (n.d.). Catabolism vs. Anabolism. [online] Available at: [Link]
anabolism-7106982 [Accessed Date].
10 - Gunnarsson, B., Entezarjou, A., Fernández-Aranda, F., Jiménez-Murcia, S., Kenttä, G. and Håkansson, A. (2022)
'Understanding exercise addiction, psychiatric characteristics and use of anabolic androgenic steroids among recreational
athletes – An online survey study', *Frontiers in Sports and Active Living*, 4, pp. 903777.
11 - Harvard Medical School (2023) 'Belmont's McLean Hospital study finds long-term anabolic-androgenic steroid use
may severely impact visuospatial memory', *Harvard Medical School*.
13 - Falqueto, H., dos Santos, M.R. and Manfredi, L.H. (2022) 'Increased muscle mass: Anabolic steroids enhance protein
synthesis in muscles, leading to increased muscle mass. This effect is particularly noticeable in strength training', *Frontiers
in Physiology*, 13, 838526. Available at: [Link] (Accessed: 22 November 2024).
12 - Endocrine Society (2018) 'Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society
Scientific Statement', *PMC*.g
14 - [Link]
15 - [Link]
16 - [Link]
17 - [Link]