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Use of Nile Tilapia (Oreochromisniloticus) skin in the management of skin burns

Article in Journal of the Pakistan Medical Association · December 2017

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LETTER TO THE EDITOR

An increase in burn cases has been reported with an ever every day.5 Recently, tilapia collagen nano-fibers are
increasing pace of life, leading to a negative socio- found to result in skin wound healing speedily and
economic impact.1 Literature shows that 0.5 million successfully in rats by promoting cell adhesion,
people with acute burn injuries are managed in the proliferation and differentiation.6 Yet another study
emergency department and 0.08 million patients are published in 2017 carried out in vitro and in vivo
hospitalized every year in the United States.2 In the experiments for wound healing evaluation, found
management of burn patients numerous topical drugs promising application of marine collagen peptides from
including 'Mafenide acetate Sol.' and 'Silver Sulfadiazine' talipia skin.4 According to the Brazilian researchers the
are used but are expensive and are associated with treatment is cheap, speeds up healing and decreases the
numerous drawbacks including severe side effects, poor need for pain medication,5 and perhaps this cheap yet
results in deep burn wounds and formation of prominent effective alternate treatment can also be employed in
scars.3 On the other hand collagen which comes from Pakistan.
sources such as cattle and pig skin or chicken waste is also
used for medicinal and pharmaceutical purposes.3,4 Disclaimer: None.
However these sources of collagen are inappropriate for Conflict of Interest: None.
use by some cultural and religious groups, and may be
contaminated leading to diseases such as mad cow Ethical Approval: As this is a "Letter to the Editor" this
disease, foot and mouth disease and transmissible manuscript does not require an Ethical Approval.
spongiform encephalopathy.3 Nile Tilapia (scientific name Funding Sources: None.
Oreochromisniloticus) is a fresh water fish and is
commonly found and cultivated in Thailand and Brazil.3,4 References
The skin of this fish is not consumed and is discarded. 1. Edelman LS. Social and economic factors associated with the risk
Talipia skin is rich in type I and III collagen fibers and has of burn injury. Burns 2007; 33: 958-65.
moisture and disease resistance similar to human skin. 2. Wasiak J, Spinks A, Ashby K, Clapperton A, Cleland H, Gabbe B. The
epidemiology of burn injuries in an Australian setting, 2000-2006.
Researchers in Brazil have developed a sterilized tilapia Burns 2009; 35: 1124-32.
skin wound dressing for second and third degree burns, 3. Potaros T, Raksakulthai N, Runglerdkreangkrai J,
on which clinical trials are being carried out and at least Worawattanamateekul W. Characteristics of collagen from nile
56 patients have received this treatment up till now.5 In tilapia (Oreochromis niloticus) skin isolated by two different
methods. Nat Sci 2009; 43: 584-93.
addition to being 75% cheaper than its alternative, Talipia 4. Hu Z, Yang P, Zhou C, Li S, Hong P. Marine Collagen Peptides from
skin wound dressing can stay as long as 10 days and the Skin of Nile Tilapia (Oreochromis niloticus): Characterization
peeled off easily afterwards, as compared to gauze and and Wound Healing Evaluation. Mar Drugs 2017; 15: 102.
silver sulfadiazine dressing which has to be changed 5. Whitaker P, Garcia P. Brazilian doctors use fish skin to treat burn
victims. [online] 2017 [Cited 2017 May 28]. Available from: URL:
[Link]
idUSKBN18L1WH.
6. Zhou T, Wang N, Xue Y, Ding T, Liu X, Mo X, et al. Electrospun
Foundation University Institute of Rehabilitation Sciences (FUIRS), Foundation
tilapia collagen nanofibers accelerating wound healing via
University, Islamabad. inducing keratinocytes proliferation and differentiation. Colloids
Correspondence: Email: osamadpt@[Link] Surf B Biointerfaces 2016; 143: 415-22.

J Pak Med Assoc

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