GOR Method for Protein Structure Prediction

Gor for bioinformatics

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GOR Method for Protein Structure Prediction

Gor for bioinformatics

Uploaded by

Unnimaya G

We take content rights seriously. If you suspect this is your content, claim it here.

Available Formats

Download as PDF, TXT or read online on Scribd

GOR

METHOD

1
DEFINITION
The original method was published by Garnier, Osguthorpe,
and Robson in 1978 and was one of the first successful
methods to predict protein secondary structure from amino
acid sequence.
GOR method assumes that aminoacids upto 8 residues on
each side has influence on secondary structure of the central
aminoacid. The algorithm uses a sliding window of 17
aminoacids.
Accuracy 64%

2
GOR VS CHOU- FASMAN
Like Chou–Fasman, the GOR method is based on probability
parameters derived from studies of known protein tertiary
structures solved by X-ray crystallography. However, unlike
Chou–Fasman, the GOR method takes into account not only
the propensities of individual amino acids to form particular
secondary structures, but also the conditional probability of
the amino acid to form a secondary structure given that its
immediate neighbors have already formed that structure.

3
4

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GOR Method for Protein Structure Prediction

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GOR Method for Protein Structure Prediction

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GOR

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